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Grants for Nonprofits - Federal

Explore 5,329 grant opportunities

Cross Border University Partnership Initiatives
$75,000
U.S. Department of State (U.S. Mission to Cote d Ivoire)
Federal

Application Deadline

Jul 4, 2025

Date Added

May 28, 2025

This funding opportunity supports partnerships between accredited universities in the U.S. and Côte d’Ivoire to promote academic exchange, joint research, and professional development initiatives that foster mutual understanding and sustainability.

Education
Nonprofits
Countering Irregular Migration
$30,000
DOS-ECU (U.S. Mission to Ecuador)
Federal

Application Deadline

Jul 15, 2024

Date Added

Jun 12, 2024

The U.S. Mission to Ecuador through the Public Diplomacy Section (PDS), announces an open competition for organizations and individuals to submit proposals to implement projects with innovative approaches to counter irregular migration in Ecuador.

International Development
Nonprofits
Grants for Adaptive Sports Programs for Disabled Veterans and Disabled Members of the Armed Forces (Adaptive Sports Grants)
$750,000
Department of Veterans Affairs (National Veterans Sports Programs)
Federal

Application Deadline

Jul 2, 2025

Date Added

Jun 4, 2025

This funding opportunity provides financial support to organizations that create and manage adaptive sports programs for disabled Veterans and members of the Armed Forces, enhancing their independence and quality of life through sports activities.

Recreation
Nonprofits
Cancer Tissue Engineering Collaborative: Enabling Biomimetic Tissue-Engineered Technologies for Cancer Research (R01 Clinical Trial Optional)
$40,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 23, 2024

Date Added

Jan 21, 2022

This grant provides funding for researchers and institutions to develop advanced tissue-engineered models that better mimic cancer biology, aiming to improve understanding and treatment of various cancer types.

Education
State governments
DoD Traumatic Brain Injury and Psychological Health, Health Services Research Award
$15,500,000
Department of Defense - Dept. of the Army -- U.S.AMRAA
Federal

Application Deadline

Jul 18, 2024

Date Added

May 17, 2024

Maturing research ideas into clinical practice and patient benefit is at the heart of all CDMRP research programs. Despite significant investment, the gap between what is possible and what is achieved remains. Even after information, tools, and interventions have been successfully evaluated in their intended populations, the development of knowledge to support their broader dissemination and implementation has often remained outside the scope. The FY24 TBIPHRP HSRA intends to bridge the gap between research, practice, and policy by building real-world evidence on how interventions, clinical practices/guidelines, and policies can be deployed to targeted populations at the appropriate time.Research Scope: The FY24 HSRA will fund clinical research (including clinical trials). Preclinical and animal research are prohibited. Prospective or retrospective clinical research or clinical trials involving human subjects, human subject data/records, and human anatomical substances are allowed. Proposed clinical trials should include interventions, clinical practices/guidelines, and policies that are well-supported within the literature and in relevant patient population(s). This award may not be used to support studies requiring an exception from informed consent (EFIC).Key aspects of the FY24 TBIPHRP HSRA: Precision Medicine Approaches: When appropriate, the TBIPHRP encourages the use of precision medicine approaches. These tailored treatments deliver the right treatment at the right time while considering an individuals unique characteristics. Community-Based Participatory Research: The application must include Community-Based Participatory Research (CBPR) approaches in the development and execution of the clinical research/trial. CBPR approaches should be documented in Attachment 8. Preliminary data are required: Inclusion of preliminary data relevant to the proposed clinical research/trial is required. Untested novel interventions are discouraged: Novel interventions that have not been evaluated in the intended population(s) are discouraged. Applicants seeking funding for novel interventions should consider one of the other FY24 TBIPHRP announcements. Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical trial appropriate to the objectives of the study. Studies utilizing human biospecimens or datasets that cannot be linked to a specific individual, gender, ethnicity, or race (typically classified as exempt from Inquiry Review Board [IRB] review) are exempt from this requirement. Clinical Trial Start Date: If applicable, the proposed clinical trial is expected to begin no later than 6 months after the award date. Intervention Availability: If applicable, the application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study.The FY24 HSRA applications may include (not all inclusive): Research that accelerates the uptake and implementation of evidence-based research into clinical practice. Comparative effectiveness research comparing the benefits and harms of emerging or established interventions and strategies to prevent, diagnose, treat, and monitor health conditions in real-world settings. Development and evaluation of strategies to overcome barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, tools, policies, and guidelines. Analysis of existing data or resources to inform clinical practice. Modification of established clinical tools for their intended population or environment. Analysis of existing clinical tools to maximize patient-relevant outcomes. Identification and analysis of the circumstances that create a need to stop or reduce (de-implement) the use of interventions, tools, policies, and guidelines that are ineffective, unproven, low-value, or harmful are within scope. Analysis of TBI and/or psychological health outcomes associated with the implementation of clinical practice guidelines, evidence-based practices, and process improvements.Early-Career Investigator Partnering Option: The FY24 TBIPHRP HSRA includes an Early-Career Investigator Partnering Option that is structured to accommodate two Principal Investigators (PIs), one of whom is an Early-Career Investigator. The combined direct costs budgeted for the entire period of performance in the applications of the Initiating PI and Partnering PI should not exceed $2.5M. The PIs may have experience in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application. One PI will be identified as the Initiating PI and will be responsible for most of the administrative tasks associated with application submission. The other investigator will be the Partnering PI. At least one of the Initiating or Partnering PIs must be an Early-Career Investigator. The intent is not to create mentor-mentee arrangement. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application is expected to describe how the PIs unique experience/expertise combined as a partnership will better address the research question, how the unique experience/expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. If recommended for funding, each PI will be named to an individual award within the recipient organization(s). For individual FY24 TBIPHRP HSRA submission requirements for the Initiating and Partnering PI, refer to S Section II.D.2, Content and Form of the Application Submission.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials. For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document.pdf.Clinical trials may be designed to evaluate pharmacologic agents (drugs or biologics), diagnostics, devices, therapies, clinical guidance, behavioral interventions, emerging approaches and technologies, and/or new indications for products currently U.S. Food and Drug Administration (FDA)-approved or -cleared. Interventions that are not FDA-regulated (or international equivalent) are within scope but the regulatory status must be documented in Attachment 12, Regulatory Strategy.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.Multi-Institutional Clinical Research/Trials: As of January 20, 2020, U.S. institutions engaged in non-exempt cooperative research must rely on a single IRB to review and approve the portion of the research conducted at domestic sites (45 CFR 46.114(b)). If the proposed, non-exempt research involves more than one U.S.-based institution, a written plan for single IRB review arrangements must be provided at the time of application submission or award negotiation. The lead institution responsible for developing the master protocol and master consent form should be identified and should be the single point of contact for regulatory submissions and requirements.Communication and data transfer between or among the collaborating institutions, as well as how specimens and/or imaging products obtained during the study will be handled, should be included in the appropriate sections of the application. A separate intellectual and material property plan agreed on by all participating institutions is also required for multi-institutional clinical research/trials.Relevance to Military Health: Relevance to the health care needs of Service Members, their Families, and Veterans is a key feature of this award. Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health: Explanation of how the project addresses an aspect of psychological health conditions and/or TBI that has direct relevance to the health and/or readiness of Service Members, their Families, and Veterans. Description of how the knowledge, information, products, or technologies gained from the proposed research could be implemented in a dual-use capacity to benefit the civilian population and also address a military need. Use of military or Veteran populations, samples, or datasets in the proposed research, if appropriate.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $15.5M to fund approximately four HSRA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

Science and Technology
Nonprofits
Elder Justice Innovation Grants FY2025
$500,000
U.S. Department of Health & Human Services (Administration for Community Living)
Federal

Application Deadline

Aug 11, 2025

Date Added

Jul 1, 2025

This funding opportunity provides financial support for organizations to develop and evaluate innovative strategies aimed at preventing and addressing elder abuse and neglect among older adults and individuals with disabilities.

Health
City or township governments
ROSES 2024: C.9 Mars Data Analysis Program
$4,500,000
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Nov 14, 2024

Date Added

Sep 25, 2024

This grant provides funding for researchers and organizations to analyze data from Mars missions, supporting advancements in our understanding of the planet's geology, climate, and potential for life.

Science and Technology
Nonprofits
Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 2, 2025

Date Added

Jan 17, 2025

This funding opportunity is designed to support a centralized leadership and coordination center that will oversee a comprehensive study on the health of adults living with HIV and similar individuals, focusing on improving health outcomes and addressing disparities through community engagement and scientific research.

Education
State governments
Major Collaborative Archival Initiatives
$350,000
NARA (National Archives and Records Administration)
Federal

Application Deadline

May 8, 2024

Date Added

Nov 27, 2023

The National Historical Publications and Records Commission seeks projects that will significantly improve public discovery and use of historical records collections. All types of historical records are eligible, including documents, photographs, born-digital records, and analog audio and moving images. Projects may focus on broad movements in U.S. history, such as law, politics, social reform, business, military, the arts, and other aspects of the national experience, or on the papers of individual figure(s) in American history. Collections that center the voices and document the history of Black, Indigenous, and People of Color are especially welcome. With the 250th anniversary of the Declaration of Independence approaching, the Commission is especially interested in projects that promote discovery and access to collections that explore the ideals behind our nations founding and the continuous debate over those ideals to the present day. Major Collaborative Archival Initiatives must be collaborations among multiple institutions that undertake either of these two eligible activities to: digitize and publish as a virtual collection online historical records housed at multiple repositories but center on a common theme, organization, or important historical figure(s); or create and test new tools and methods for the archival field to enhance public access, especially for born-digital records. Projects that actively engage the public in the work of the project will be more competitive. If you have a project that will process and/or digitize collections and will not require more than $150,000 in grant funds, you should consult the Archival Projects program. A successful Major Collaborative Archival Initiative proposal will: demonstrate the value of the contents of the collections, outline a project that addresses best practices for the work, be appropriately staffed, propose a budget that accomplishes the project in a cost-effective manner, and outline activities that bring researchers to the collections included in the project as well as the rest of the repositorys holdings. Award Information A grant is for one to three years. Awards will be between $150,000 and $350,000. The NHPRC expects to make up to five grants in this category for a total of up to $1,000,000. Grants begin no earlier than January 1, 2025. The Commission requires that grant recipients acknowledge NHPRC grant assistance in all publicity, publications, and other products that result from its support. Eligibility Eligible applicants: U.S. nonprofit organizations or institutions U.S. colleges, universities, and other academic institutions State or local government agencies Federally-acknowledged or state-recognized Native American tribes or groups Projects must be collaborations that include at least one of the eligible activities described for this program. Applications must include all required elements (SF424, Project Narrative, NHPRC Budget form, and Supplemental Materials). Applications that do not meet either of these criteria will not be considered. In order to ensure eligibility, applicants should first review the rules and regulations governing NHPRC grants under the Administering an NHPRC Grant section. Cost Sharing The total costs of a project are shared between the NHPRC and the applicant organization. Cost sharing is required. The applicant's financial contribution may include both direct and indirect expenses, in-kind contributions, non-Federal third-party contributions, and any income earned directly by the project. NHPRC grant recipients are not permitted to use grant funds for indirect costs (as indicated in 2 CFR 2600.101). Indirect costs must be listed under the applicant's cost sharing contribution if they are included in the budget. The Commission provides no more than 50 percent of total project costs in the Major Collaborative Archival Initiatives program. Other Requirements Applicant organizations must be registered in the System for Award Management (SAM) prior to submitting an application, maintain SAM registration throughout the application and award process, and include a valid Unique Entity Identifier (UEI) number in their application. Details on SAM registration and requesting a UEI number can be found at the System for Award Management website at https://sam.gov. Please refer to the User Guides section and the Grants Registrations PDF. Ensure your SAM.gov and Grants.gov registrations and passwords are current. It may take up to one month to register or reactivate your registration with SAM.gov and Grants.gov. NHPRC will not grant deadline extensions for lack of registration.

Humanities
State governments
2025 Rural Emergency Medical Services Training Grant
$10,400,000
Substance AbU.S.e and Mental Health Services Administration (SAMHSA)
Federal

Application Deadline

Mar 20, 2025

Date Added

Feb 28, 2024

This grant provides funding to rural emergency medical services to train personnel in effectively addressing substance use disorders and mental health conditions, enhancing their ability to support underserved populations in emergency situations.

Health
Nonprofits
High Energy Cost Grants
$3,000,000
U.S. Department of Agriculture (Rural Utilities Service)
Federal

Application Deadline

Feb 28, 2025

Date Added

Dec 30, 2024

This program provides funding to communities facing extremely high energy costs to improve their energy infrastructure and promote renewable energy solutions.

Business and Commerce
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed)
$1,300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 10, 2024

Date Added

Sep 27, 2024

This funding opportunity is designed to support research sites that will enroll patients with Type 1 Diabetes at risk of kidney disease, enabling the study of kidney biopsies to advance understanding and treatment of diabetic nephropathy.

Health
State governments
Infrastructure Investment and Jobs Act (IIJA): Mine of the Future - Proving Ground Initiative
$40,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Jan 30, 2026

Date Added

Nov 17, 2025

This funding opportunity provides financial support for the establishment of national-scale testing facilities for innovative mining technologies, aimed at enhancing the U.S. critical minerals supply chain through collaborative projects among academia, industry, and other stakeholders.

Natural Resources
Public and State controlled institutions of higher education
NIJ FY24 Research and Evaluation on the Administration of Justice: Prosecution Practice, Justice, Case Tracking, and Workforce
$2,000,000
USDOJ-OJP-NIJ (National Institute of Justice)
Federal

Application Deadline

May 8, 2024

Date Added

Feb 25, 2024

With this solicitation, NIJ seeks to fund proposals for rigorous research and evaluation projects examining the impact of court and other criminal justice tools, practices, and policies on the administration of justice and public safety in state, local, and tribal jurisdictions. In FY2024, the solicitation is focused on four research priorities and their impact on charging, case flow, outcomes, and other prosecution functions: 1) advance prosecution practice and resource management; 2) promote fair prosecution and impartial administration of justice; 3) build prosecution data resources, research capacity, and transparency; and 4) enhance the prosecution workforce and court workgroup.

Science and Technology
State governments
U.S. Embassy Paraguay - PD Annual Program Statement Fiscal Year 2024
$20,000
DOS-PRY (U.S. Mission to Paraguay)
Federal

Application Deadline

Jul 5, 2024

Date Added

Jan 30, 2024

The Public Diplomacy Section of the Embassy of the United States in Paraguay is pleased to announce that funding is available through its Fiscal Year 2024 Public Diplomacy Grants Program. This is an Annual Program Statement, outlining our funding priorities, the strategic themes we focus on, and the procedures for submitting requests for funding. The PD section seeks to inform and share with audiences in Paraguay about the United States, its culture, society, government, legal, economic, and political systems, and values through programs focusing on the priority areas outlined in the full Annual Program Statement for FY 2024 document.

International Development
Nonprofits
Child Care and Development Fund (CCDF) Lead Agency Data and Research Capacity Grants
$150,000
HHS-ACF-OPRE (Administration for Children and Families - OPRE)
Federal

Application Deadline

Jun 20, 2024

Date Added

Jan 12, 2024

The Office of Planning, Research and Evaluation (OPRE), within the Department of Health and Human Services' (HHS) Administration for Children and Families (ACF), plans to solicit applications for cooperative agreements under the Child Care and Development Fund (CCDF) Lead Agency Data and Research Capacity: Planning Grants (Phase I). These projects are meant to support partnerships between CCDF Lead Agencies and researchers to develop and improve state, territory, and Tribal data systems and build the capacity of CCDF Lead Agencies to collect, analyze, and use data to guide child care policy decisions and program improvement efforts. Sponsored projects will work in collaboration to: (1) assess the current data and research capacity of the CCDF Lead Agency; (2) develop questions of interest to investigate state, territory, and Tribal child care policies and practices; (3) develop logic models to identify the data needed to address the questions of interest; (4) identify data sources available to answer questions of interest and assess the accessibility of those data; (5) identify possible data sources from other state, territory, Tribal, and local data systems for linking; (6) determine whether there is a need to collect data to answer policy-relevant questions; and (7) address the barriers to collecting, analyzing, and using data to inform child care policy decisions. These projects are intended to build the capacity of CCDF Lead Agencies to use data, including data on children, families, the workforce, and providers that participate in the child care subsidy system, to make data-informed decisions to improve child care policies and practices. These 18-month projects, with one project and budget period, will fund a planning phase to develop a research plan to address questions of interest to the CCDF Lead Agency, including a plan for identifying, linking, and using state, territory, and Tribal data to inform child care policy decisions. These planning projects may be followed by a second competition (Phase II), under a separate Notice of Funding Opportunity, to support execution of the research plans to develop and improve state, territory, and Tribal data systems. Projects must be conducted through partnerships between CCDF Lead Agencies (i.e., states, territories, Tribes, or local subsidy administering agencies) and researchers from institutions of higher education, within the state agency, research organizations, and/or other organizations with proven expertise conducting policy research. Applications are invited from CCDF Lead Agencies, institutions of higher education, research organizations, and other organizations with proven expertise conducting policy research. The research supported by this program should be collaborative from start to finish. The CCDF Lead Agency and their research partners must work together to assess the current data and research capacity of the CCDF Lead Agency and develop a feasible plan for identifying, linking, and using data to address questions of relevance to the CCDF Lead Agency. Sponsored projects will be expected to participate in a Consortium that will meet and communicate regularly to identify opportunities for coordination, such as to share information on facilitators and barriers to identifying and using data to inform child care policies and methods for linking data across systems, and to develop collective expertise and resources for the field. The Consortiums collaboration will support research capacity and learning within individual projects and across award recipients. Funding is subject to availability of funds and the best interests of the federal government.

Income Security and Social Services
State governments
Partnership for National Maternal and Child Health (MCH) Leadership
$1,622,500
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Jan 3, 2025

Date Added

Jul 26, 2024

This funding opportunity provides financial support to various organizations focused on improving maternal and child health services across the United States, including state programs, urban initiatives, and home visiting services.

Health
State governments
Career Skills Training Program
$1,100,000
U.S. Department of Energy
Federal

Application Deadline

Mar 6, 2025

Date Added

Jan 9, 2025

This program provides funding to nonprofit partnerships between industry and labor organizations to train individuals in energy efficiency technologies, helping them gain certifications and secure good jobs, particularly in underserved communities.

Workforce Development
Nonprofits
Poison Control Program Competitive Supplement
$265,188
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Apr 22, 2025

Date Added

Jan 21, 2025

This funding opportunity provides financial support to accredited organizations in Puerto Rico to enhance poison control services and improve public health responses to poisoning incidents.

Health
State governments
Innovative Approaches to Studying Cancer Communication in the New Information Ecosystem (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 22, 2024

Date Added

Jun 13, 2022

This grant provides funding for researchers to develop innovative methods for improving cancer communication and prevention strategies in today's digital landscape, focusing on the impact of online information and health disparities.

Education
State governments