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Grants for Nonprofits - Federal

Explore 6,018 grant opportunities

Expeditions in Computing
$15,000,000
National Science Foundation
Federal

Application Deadline

Mar 31, 2027

Date Added

Jul 18, 2025

This funding opportunity supports U.S. higher education institutions and their partners in conducting transformative, long-term research in computing and information science, with a focus on collaboration and broadening participation in the field.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Oct 24, 2024

This funding opportunity supports the development of advanced sensors and devices to better understand the connection between brain activity and behavior, inviting applications from a diverse range of organizations, including nonprofits, educational institutions, and small businesses.

Health
State governments
National Center for Construction Safety and Health Research and Translation (U54)
$5,750,000
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Dec 1, 2026

Date Added

Sep 13, 2023

This grant provides funding for organizations to conduct research and develop solutions aimed at improving safety and health for construction workers across the United States.

Health
State governments
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 7, 2024

This funding opportunity supports research projects that improve the use of mammalian models, like organoids and tumoroids, to advance cancer research and develop effective treatments for patients.

Education
State governments
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 7, 2024

This grant provides funding for researchers to develop and integrate imaging and liquid biopsy techniques to improve cancer treatment monitoring and early detection of treatment resistance.

Education
State governments
Rural Microentrepreneur Program(RMAP)
$500,000
U.S. Department of Agriculture (Rural Business-Cooperative Service )
Federal

Application Deadline

Jun 30, 2026

Date Added

Feb 27, 2026

This program provides financial support and technical assistance to nonprofit organizations, Indian Tribes, and educational institutions to help rural entrepreneurs start and grow their small businesses.

Business and Commerce
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2026

Date Added

Sep 26, 2024

This grant provides funding for researchers to develop small molecule drugs targeting nervous system disorders, with support from NIH resources for drug discovery and clinical testing.

Education
State governments
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 5, 2027

Date Added

Jun 18, 2025

This funding opportunity supports collaborative research projects that bring together NIH scientists and external researchers to advance patient-centered clinical studies using the unique resources of the NIH Clinical Center.

Health
State governments
NIJ FY25 Research and Evaluation on School Safety
$3,600,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Jun 3, 2026

Date Added

May 4, 2026

This funding opportunity provides financial support for non-federal entities to conduct long-term monitoring and analysis of phytoplankton and chlorophyll-a in the Great Lakes, helping to assess ecosystem health and inform environmental management decisions.

Environment
State governments
Grants for Arts Projects
$150,000
National Endowment for the Arts
Federal

Application Deadline

Jul 9, 2026

Date Added

Feb 14, 2025

This funding opportunity supports U.S.-based nonprofit organizations, local governments, and tribal communities in creating arts projects that engage the public and promote health and well-being through various artistic disciplines.

Arts
Nonprofits
DoD Multiple Sclerosis Investigator-Initiated Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 13, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, treatment, and quality of life for individuals affected by multiple sclerosis, particularly benefiting Service Members, Veterans, and their families.

Health
Nonprofits
DoW Military Burn, Technology/Therapeutic Development Award
$1,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers and organizations developing innovative technologies and treatments to improve burn care for military personnel injured in combat or training environments.

Science and Technology
Nonprofits
EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Infrastructure Innovation for Biological Research
$800,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 23, 2025

This program provides funding for the development of innovative research tools and methods that enhance biological research, targeting universities, community colleges, and nonprofit organizations involved in biological sciences.

Science and Technology
Public and State controlled institutions of higher education
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)
$249,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Nov 8, 2023

This grant provides financial support to early-stage postdoctoral researchers in cancer-related fields, helping them transition from mentored training to independent research careers.

Health
State governments
BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 17, 2026

Date Added

Nov 25, 2024

This funding opportunity supports research partnerships between resource-limited institutions and experienced technology developers to enhance the use of innovative neurotechnologies for better understanding and treating brain-related conditions.

Health
Public and State controlled institutions of higher education
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education