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Grants for Nonprofits - Federal

Explore 6,593 grant opportunities

NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 24, 2026

Date Added

Dec 19, 2024

This funding opportunity supports researchers conducting basic experimental studies with human participants to advance scientific knowledge in health and disease processes.

Education
State governments
FY 2026 Assistance for Local Emergency Response Training (ALERT) Grant
$500,000
U.S. Department of Transportation (Pipeline and Hazardous Materials Safety Admin)
Federal

Application Deadline

Jun 22, 2026

Date Added

May 19, 2026

This funding opportunity provides financial support to nonprofit organizations that deliver specialized training for emergency responders dealing with hazardous materials incidents, particularly those involving flammable liquids transported by rail.

Employment Labor and Training
Nonprofits
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
$2,400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 21, 2024

This funding opportunity supports the establishment of facilities that will produce and distribute specialized brain cell access tools for neuroscience research, enabling scientists to better study and manipulate specific brain cell types.

Health
Public and State controlled institutions of higher education
Leading Edge Acceleration Projects (LEAP) in Health Information Technology
$1,000,000
U.S. Department of Health & Human Services (Office of the National Coordinator)
Federal

Application Deadline

Jul 16, 2026

Date Added

Jun 14, 2022

This funding opportunity supports innovative projects that improve health information technology, focusing on artificial intelligence, API monitoring, and laboratory data interoperability, and is open to public and nonprofit institutions, including universities and local governments.

Health
Nonprofits
Strategies to Improve Health Outcomes and Reduce Health Disparities in Rural Populations (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 14, 2025

This funding opportunity supports research projects aimed at improving health outcomes and reducing disparities in rural communities by addressing social determinants of health through innovative interventions and collaborations.

Health
State governments
Alumni Engagement Innovation Fund (AEIF) 2026
$30,000
U.S. Department of State (U.S. Mission to Guinea)
Federal

Application Deadline

May 7, 2026

Date Added

Apr 9, 2026

This funding opportunity provides financial support for alumni of U.S. government-funded exchange programs in Guinea to implement community-based projects that promote shared values and address local challenges, particularly in celebration of the United States' 250th anniversary.

International Development
Nonprofits
FY26 Community Policing Development (CPD) Accreditation Program
$350,000
U.S. Department of Justice (Community Oriented Policing Services)
Federal

Application Deadline

Aug 27, 2026

Date Added

Jul 22, 2026

This funding opportunity provides financial support to organizations that help law enforcement agencies achieve accreditation, particularly focusing on small and rural departments, by removing barriers and enhancing accreditation systems.

Law Justice and Legal Services
State governments
Advisory Committee Coordination Support for the Chesapeake Bay Program Partnership
$2,450,000
U.S. Environmental Protection Agency
Federal

Application Deadline

May 1, 2026

Date Added

Mar 11, 2026

This funding opportunity provides financial support for organizations to coordinate and support advisory committees that contribute to the restoration and protection of the Chesapeake Bay, benefiting diverse stakeholders across the watershed.

Environment
Native American tribal organizations
Alumni Engagement Innovation Fund (AEIF) 2026
$35,000
U.S. Department of State (U.S. Mission to Burundi)
Federal

Application Deadline

May 4, 2026

Date Added

Apr 3, 2026

This funding opportunity supports alumni of U.S. government-sponsored exchange programs in Burundi to implement innovative projects that promote youth engagement, entrepreneurship, and educational access while strengthening ties with the United States.

International Development
Individuals
Office of Elementary and Secondary Education (OESE): Well-Rounded Education Programs: Jacob K. Javits Gifted and Talented Students Education (Javits) Program
$650,000
U.S. Department of Education
Federal

Application Deadline

Jun 23, 2026

Date Added

Apr 23, 2026

This funding opportunity provides financial support to educational agencies and organizations to develop innovative strategies for identifying and serving gifted and talented students, particularly those from underserved backgrounds.

Education
State governments
AFCEC Land Management Mapping for CONUS/Europe/PACAF Air Force Installations
$59,332,041
U.S. Department of Defense (Fort Worth District)
Federal

Application Deadline

May 26, 2026

Date Added

Apr 24, 2026

This funding opportunity is designed to support organizations involved in environmental conservation and land management by providing resources for geospatial data collection and analysis across U.S. Air Force installations in the continental U.S., Europe, and the Pacific.

Natural Resources
Public and State controlled institutions of higher education
Lewis Houghton Civics and Democracy Initiative - Continuing Awards
$250,000
Library of Congress
Federal

Application Deadline

May 18, 2026

Date Added

Apr 21, 2026

This funding opportunity provides financial support to existing partner organizations of the Library of Congress to enhance and expand civic education programs using the Library's digital collections.

Education
Nonprofits
AI3 Action Institute - Artificial Intelligence for American Indians
$3,500,000
U.S. Department of Health and Human Services (Administration for Children and Families - ANA)
Federal

Application Deadline

Aug 27, 2026

Date Added

May 7, 2026

This funding opportunity provides resources to Native American communities and organizations to establish a national institute focused on the responsible use and governance of artificial intelligence technologies for socioeconomic development and cultural alignment.

Opportunity Zone Benefits
Native American tribal organizations
Cooperative Agreement for affiliated Partner with the Great Lakes Northern-Forest Cooperative Ecosystem Studies Unit
$299,971
U.S. Department of the Interior (Geological Survey)
Federal

Application Deadline

Jun 29, 2026

Date Added

Nov 27, 2025

This funding opportunity provides financial support for institutions involved in scientific research and conservation efforts to restore native mussel populations in the Great Lakes region, specifically targeting the Indiana Dunes National Park.

Science and Technology
Public and State controlled institutions of higher education
Comprehensive Addiction and Recovery Act (CARA)
$75,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCIPC)
Federal

Application Deadline

Jun 8, 2026

Date Added

Feb 20, 2026

This funding opportunity provides financial support to community coalitions focused on preventing and reducing opioid and methamphetamine use, as well as prescription drug misuse among youth aged 12 to 18 in areas experiencing higher-than-average substance misuse rates.

Health
Nonprofits
National Communication System for Runaway and Homeless Youth Program
$1,800,000
U.S. Department of Health and Human Services (Administration for Children ; Families - ACYF/FYSB)
Federal

Application Deadline

Aug 19, 2026

Date Added

Apr 28, 2026

This funding opportunity provides financial support to nonprofit organizations and government entities to establish a nationwide communication system that assists runaway and homeless youth by connecting them with crisis intervention services and resources.

Income Security and Social Services
Nonprofits
DoW Prostate Cancer, Data Science Award
$1,400,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers and organizations using data science to analyze complex prostate cancer datasets, aiming to improve patient outcomes and advance scientific knowledge in the field.

Science and Technology
Nonprofits
NIJ FY 2026 Research and Evaluation of Services for Victims of Crime
$1,500,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Aug 14, 2026

Date Added

Jul 23, 2026

This funding opportunity provides financial support for research and evaluation projects aimed at improving services and outcomes for victims of crime, targeting a wide range of eligible organizations including nonprofits, educational institutions, and government entities.

Science and Technology
Nonprofits
U.S. Mission Iraq Public Diplomacy Annual Program Statement 2026
$500,000
U.S. Department of State (U.S. Mission to Iraq)
Federal

Application Deadline

Aug 15, 2026

Date Added

May 19, 2026

This funding opportunity provides financial support for projects that foster cultural, educational, and professional connections between the United States and Iraq, targeting nonprofit organizations, educational institutions, and individuals engaged in promoting U.S. values and partnerships.

International Development
Nonprofits
Infrastructure Investment and Jobs Act (IIJA) Speed to Power through Accelerated Reconductoring and other Key Advanced Transmission Technology Upgrades (SPARK)
$250,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

May 20, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support to U.S. entities involved in enhancing the electric grid's capacity and reliability through advanced transmission technologies and infrastructure upgrades.

Energy
State governments