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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

BJA FY24 Comprehensive Opioid, Stimulant and Substance Use Program (COSSUP) Overdose Fatality Review (OFR) Training and Technical Assistance (TTA)
$2,000,000
USDOJ-OJP-BJA (Bureau of Justice Assistance)
Federal

Application Deadline

Jul 17, 2024

Date Added

May 28, 2024

With this solicitation, BJA seeks a training and technical assistance (TTA) provider to help jurisdictions prevent and reduce overdose deaths as part of the Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP). COSSUP provides funding and TTA to state, local, and tribal governments to develop, implement, or expand comprehensive programs in response to the overdose crisis and impacts of illicit opioids, stimulants, or other substances. This COSSUP Overdose Fatality Review (OFR) TTA Program provides training and supports collaborations that prevent and reduce overdose deaths. This program helps jurisdictions build and enhance multidisciplinary collaborations, collect and use multisector data, and conduct confidential individual death reviews in order to identify trends, incidents, and gaps in prevention efforts and services to inform innovative, community-specific overdose prevention and intervention strategies.

Humanities
Public and State controlled institutions of higher education
BJA FY25 Staff-Led Restrictive Housing Reform Program
$2,000,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Mar 4, 2025

Date Added

Jan 13, 2025

This grant provides funding to organizations that will assist correctional facilities in reforming restrictive housing practices, focusing on reducing solitary confinement while ensuring safety and compliance with federal standards.

Law Justice and Legal Services
Public and State controlled institutions of higher education
HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)
$650,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 6, 2025

Date Added

Oct 9, 2024

This funding opportunity supports research projects that investigate individual differences in pain experiences and treatment responses, aiming to develop personalized pain management strategies while addressing the opioid crisis.

Education
State governments
Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 20, 2025

Date Added

May 22, 2025

This funding opportunity supports U.S.-based organizations in evaluating the impact of upcoming public policies and programs that aim to improve health behaviors and reduce chronic disease risk factors through behavioral changes.

Education
State governments
Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed) 2025
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 5, 2025

Date Added

Dec 10, 2024

This funding opportunity supports researchers conducting time-sensitive studies that enhance ongoing clinical projects related to arthritis, musculoskeletal, and skin diseases, aiming to improve understanding and treatment of these conditions.

Health
Public and State controlled institutions of higher education
Air Delivered Effects
$750,000,000
U.S. Department of Defense (Munitions Directorate)
Federal

Application Deadline

Not specified

Date Added

Mar 22, 2022

This funding opportunity supports research and development of advanced air-delivered weapon systems and technologies, inviting proposals from universities, nonprofits, and small businesses to enhance national defense capabilities.

Science and Technology
Private institutions of higher education
Precision Approaches in Radiation Synthetic Combinations (PAIRS, R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 16, 2025

Date Added

Jun 14, 2022

This funding opportunity supports innovative research to develop combination cancer therapies that integrate radiation treatment with targeted molecular agents, aimed at improving treatment effectiveness while reducing side effects.

Education
State governments
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
$300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 10, 2026

Date Added

Sep 9, 2025

This funding opportunity supports the advanced development and validation of innovative technologies aimed at improving cancer research, targeting a diverse range of organizations capable of contributing to this field.

Health
State governments
4th Mekong Research Symposium
$430,000
Department of State - Bureau of Oceans - Int. Environmental - Scientific
Federal

Application Deadline

Jul 21, 2024

Date Added

May 28, 2024

The U.S. Department of State, Bureau of Oceans and International Environmental and Scientific Affairs Office of Conservation, and Water (OES) announces the Notice of Funding Opportunity (NOFO) for a program to help address and identify solutions to shared water challenges in the Mekong sub-region by developing and hosting the 4th Mekong Research Symposium (MRS), under the Mekong-U.S. Partnership (MUSP). The MRS will convene stakeholders (including academia, private sector, media and journalists, local government, donors, development and financing partners, non-profits, civil society organizations, and indigenous communities) to present on advancements in science and technology, including local solutions, and raise awareness of existing initiatives and resources to provide long-term, equitable benefits across the sub-region.

Environment
Nonprofits
Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

May 22, 2025

This funding opportunity supports the establishment of Clinical Coordinating Centers for multi-site clinical trials focused on heart, lung, and blood health issues, encouraging collaboration and community engagement to improve trial efficiency and address health disparities.

Health
State governments
Disruptive DC Converters For Grid Resilient Infrastructure To Deliver Sustainable Energy Sbir/STTR (Dc-Grids Sbir/STTR)
$4,505,859
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Mar 3, 2025

Date Added

Nov 8, 2024

This funding opportunity provides financial support for small businesses and research institutions in the U.S. to develop innovative high-voltage direct current technologies that improve grid resilience and facilitate the integration of renewable energy sources.

Opportunity Zone Benefits
Small businesses
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs
$305,000
National Science Foundation
Federal

Application Deadline

Nov 5, 2025

Date Added

Jun 2, 2025

This grant provides funding to small businesses in the U.S. to develop innovative technologies with the potential for commercial success and societal impact.

Science and Technology
Small businesses
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 8, 2025

Date Added

Oct 31, 2023

This funding opportunity supports U.S.-based researchers and organizations in developing non-addictive pain relief therapies to combat the opioid crisis, with a focus on advancing preclinical candidates toward clinical trials.

Education
State governments
ROSES25: D.7 Strategic Astrophysics Technology
$5,000,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This grant provides funding to universities, research organizations, and private companies to develop and validate advanced technologies for future NASA space missions focused on understanding the universe and detecting exoplanets.

Science and Technology
Public and State controlled institutions of higher education
Changing Health Systems Using Evidence-based interventions to increase Colorectal Cancer Screening
$900,000
U.S. Department of Health & Human Services (Centers for Disease Control - NCCDPHP)
Federal

Application Deadline

Feb 20, 2025

Date Added

Aug 13, 2024

This funding opportunity provides financial support to various organizations, including health centers and nonprofits, to implement evidence-based strategies that increase colorectal cancer screening rates among underserved populations aged 45 to 75.

Health
State governments
NCI National Clinical Trials Network - Network Lead Academic Participating Sites (UG1 Clinical Trial Not Allowed)
$1,700,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 24, 2025

Date Added

Oct 11, 2024

The "NCI National Clinical Trials Network - Network Lead Academic Participating Sites" grant is a funding opportunity from the National Cancer Institute for academic centers to provide scientific leadership and patient recruitment for large-scale, multi-institutional cancer clinical trials, with a focus on treatment trials, rare cancers, and underserved populations, offering up to $1.7 million per year for a six-year project period.

Education
State governments
Infrastructure Investment and Jobs Act (IIJA) Section 40207 Battery Materials Processing Battery Manufacturing and Recycling Grant Programs
$100,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Apr 24, 2026

Date Added

Mar 16, 2026

This funding opportunity provides financial support to U.S. entities for developing domestic infrastructure in battery material processing, manufacturing, and recycling to strengthen the supply chain for critical minerals essential for advanced batteries.

Energy
Nonprofits
Rural Community Health Support Program
$4,500,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Jul 8, 2026

Date Added

Feb 19, 2026

This funding opportunity provides financial support to organizations that deliver technical assistance to improve healthcare access and outcomes in underserved rural communities across the United States.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Contact for amount
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

May 28, 2024

Date Added

Nov 24, 2023

The purpose of this Notice is to announce the intention of National Institutes of Neurological Disorders and Stroke (NINDS) to reissue RFA-NS-21-021 to solicit applications for research pursuing translational activities and small clinical studies to advance the development of low risk therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Spring 2024 with an expected application due date in Summer 2024. This NOFO will utilize the R61/R33 activity code. Details of the planned NOFO are provided below.

Health
State governments
Supplemental Opportunity for SBIR/STTR Memberships in I/UCRCs
Contact for amount
National Science Foundation
Federal

Application Deadline

Feb 18, 2026

Date Added

Feb 19, 2026

This funding opportunity provides financial support for small businesses with existing SBIR or STTR grants to join collaborative research centers, enhancing their access to academic research and industry partnerships for innovation and commercialization.

Science and Technology
Small businesses