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Grants for Small businesses - Federal

Explore 1,531 grant opportunities

DRL FY23 Citizens Engage on New GBV Law in Uzbekistan
$900,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

May 6, 2024

Date Added

Mar 8, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for projects that combats Gender Based Violence in Uzbekistan. The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for projects that combat gender-based violence (GBV) in Uzbekistan.        ​​​On April 6, 2023, Uzbekistan’s Senate unanimously adopted amendments criminalizing domestic violence and strengthening protections for women and children.  The legislation, signed into law by President Mirziyoyev on April 11, amends the Criminal and Administrative Codes.  While this legislation amended the Criminal and Administrative Codes, there are a few barriers to making the law a reality.  First, there is uneven implementation across localities because of cultural and resource variances across urban, peri-urban, and rural communities.  Second, limited public knowledge about the new law has resulted in few people seeking access to legal assistance.  Lastly, societal norms impede individuals from reporting domestic violence.     Through this award, DRL aims to address these gaps by:      Increasing awareness among all Uzbekistanis about the new GBV law at the local level and how it applies to women and communities across Uzbekistan.  Raising awareness about harmful practices that normalize and excuse GBV toward women and girls.  Supporting local civil society, community leaders, and social workers as they advocate to local law enforcement and local governance structures for the consistent implementation of the new law at the local level.     The proposed program should achieve the following outcomes:    Local civil society organizations (CSOs) and community advocates are better equipped to promote awareness of the new GBV law and advocate for its consistent and accountable implementation with law enforcement and government structures.   CSOs are better able to advocate for and assist GBV survivors to ensure they have access to resources and all provisions provided under the new GBV law.   Communities better understand and can advocate for the even implementation of the new GBV law at the local level.  Improved data collection and monitoring of GBV case response under the new law, All programs should aim to have impact that leads to reforms and have the potential for sustainability beyond DRL resources.  DRL’s preference is to avoid duplicating past efforts by supporting new and creative approaches.  This does not exclude from consideration projects that improve upon or expand existing successful projects in a new and complementary way.  DRL is committed to advancing equity and support for underserved and underrepresented communities. In accordance with the Executive Order on Advancing Racial Equity and Underserved Communities, programs should implement strategies for integration and inclusion of individuals/organizations/beneficiaries that can bring perspectives based on their religion, sex, disability, race, ethnicity, sexual orientation, gender identity, gender expression, sex characteristics, national origin, age, genetic information, marital status, parental status, pregnancy, political affiliation, or veteran’s status.  Programs should be demand-driven and locally led to the extent possible.  DRL requires all programs to be non-discriminatory and expects implementers to include strategies for nondiscrimination of individuals/organizations/beneficiaries based on race, color, religion, sex, gender identity, gender expression, sex characteristics, sexual orientation, pregnancy, national origin, disability, age, genetic information, marital status, parental status, political affiliation, or veteran’s status.  Competitive proposals may also include a summary budget and budget narrative for no additional months following the proposed period of performance, indicated above. This information should indicate what objective(s) and/or activities could be accomplished with additional time and/or funds beyond the proposed period of performance. Where appropriate, competitive proposals may include: Opportunities for beneficiaries to apply their new knowledge and skills in practical efforts; Solicitation of feedback and suggestions from beneficiaries when developing activities in order to strengthen the sustainability of programs and participant ownership of project outcomes; Input from participants on sustainability plans and systematic review of the plans throughout the life of the project, with adjustments made as necessary; Joint identification and definition of key concepts with relevant stakeholders and stakeholder input into project activities; Systematic follow-up with beneficiaries at specific intervals after the completion of activities to track how beneficiaries are retaining new knowledge as well as applying their new skills. Activities that are not typically allowed include, but are not limited to: The provision of humanitarian assistance; English language instruction; Development of high-tech computer or communications software and/or hardware; Purely academic exchanges or fellowships; External exchanges or fellowships lasting longer than six months; Off-shore activities that are not clearly linked to in-country initiatives and impact or are not necessary per security concerns; Theoretical explorations of human rights or democracy issues, including projects aimed primarily at research and evaluation that do not incorporate training or capacity-building for local civil society; Micro-loans or similar small business development initiatives; Initiatives directed towards a diaspora community rather than current residents of targeted countries.

International Development
Nonprofits
NIOSH Small Research Grant Program
$50,000
U.S. Department of Health & Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Nov 21, 2025

Date Added

Jan 14, 2025

This program provides funding to various organizations for research projects that improve workplace safety and health by identifying and reducing occupational hazards.

Health
State governments
U.S. Wave Energy Open Water Testing
$25,313,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Jan 30, 2025

Date Added

Sep 25, 2024

This funding opportunity provides financial support for projects that advance the development and testing of wave energy technology, targeting distributed, community, and utility applications in the United States.

Energy
Nonprofits
Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2024

Date Added

Nov 10, 2022

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states.

Health
State governments
DOD Amyotrophic Lateral Sclerosis, Pilot Clinical Trial Award
$2,800,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 27, 2025

Date Added

May 27, 2025

This funding opportunity supports clinical trials aimed at improving treatments and care for individuals with amyotrophic lateral sclerosis (ALS), encouraging collaboration with patients and caregivers in the research process.

Science and Technology
Nonprofits
Miniaturization and Automation of Tissue Chip Systems (MATChS) (UT1/UT2 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Nov 21, 2023

This funding opportunity supports U.S. small businesses in developing innovative, automated, and miniaturized tissue chip systems for biomedical research, drug development, and precision medicine.

Health
Small businesses
Knowledge SUCCESS II
$50,000,000
U.S. Agency for International Development
Federal

Application Deadline

Oct 18, 2024

Date Added

Aug 23, 2024

The "Knowledge SUCCESS II" grant is intended to enhance the integration of Knowledge Management (KM) into global health and development programs, aiming to improve accessibility, engage marginalized groups, and achieve better outcomes by serving stakeholders like health officials, advisors, and donor staff.

Health
Nonprofits
DoD Epilepsy Virtual Post-Traumatic Epilepsy Research Center Faculty Award
$1,680,000
DOD-AMRAA (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jun 20, 2024

Date Added

Mar 26, 2024

The ERP seeks to solicit Faculty members to join the Virtual Post-Traumatic Epilepsy Research Center (P-TERC) in order to advance PTE research through development of early-career investigators and investigators new to the PTE field. The ERP Virtual P-TERC is a unique, interactive virtual research center providing intensive mentoring, national networking, collaborations, and a peer group for new PTE investigators. The overarching goal of the Virtual P-TERC is to develop successful, highly productive PTE researchers in a collaborative research and career development environment to enhance quality and expand quantity of the PTE research field. The Virtual P-TERC is a multi-institutional career development and research training platform that consists of Faculty and their Career Guides (primary mentors) and is managed by a Director and Deputy Director. The Virtual P-TERC Leadership (the Director and the Deputy Director) serve as a resource for the Faculty and Career Guides, assessing the progress of Faculty and facilitating communication and collaboration among all of the Faculty and Career Guides, as well as with national research societies and representatives from the community with lived PTE experience. In addition to fostering scientific development, the Virtual P-TERC, through its Leadership, provides for professional and leadership development of the Faculty to include skills and competencies needed to fund and manage a productive PTE research laboratory.

Science and Technology
Nonprofits
DoD Peer Reviewed Medical, Impact Award
$47,400,000
DOD-AMRAA (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jun 6, 2024

Date Added

Mar 27, 2024

The FY24 PRMRP Impact Award supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from the real-world environment, to foster clinical applicability. The intent of the Impact Award is to translate the fundamental understanding of underlying mechanisms toward practical applications that have the potential for major near-term impact on patients affected by one of the diseases and conditions included in the FY24 PRMRP Topic Areas.Proposed research should refine mature concepts and ideas into translatable solutions with a view toward evaluating technical feasibility of promising new pharmacological agents, knowledge products, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance, and/or emerging approaches and technologies. The FY24 PRMRP Impact Award is not intended to support basic research.For the purposes of this funding opportunity, basic research is defined as exploratory science directed toward greater knowledge or understanding of the fundamental aspects of phenomena or outcomes, without specific applications toward process and products. Examples include, but are not limited to, high-risk/high-gain approaches, mechanistic studies, and preliminary data generation/validation. Applicants seeking funding for research that meets this definition should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.Pre-Application (Letter of Intent) Submission Deadline: 5:00 p.m. Eastern time (ET), May 13, 2024

Science and Technology
Nonprofits
Viral INfections in the Young Lung- The VINYL Clinical Consortium- Data Analytics and Coordinating Center (DACC) (U24 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 10, 2025

Date Added

Jul 9, 2025

This grant provides funding to establish a Data and Analytics Coordinating Center that will support research on viral lung infections in young children by managing data and coordinating efforts among multiple clinical sites.

Health
State governments
DoD Spinal Cord Injury Research Program Investigator-Initiated Research Award
$6,720,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 30, 2024

Date Added

Mar 26, 2024

The SCIRP IIRA is intended to support studies that have the potential to make an important contribution to SCI research, patient care, and/or quality of life.Important aspects of this award mechanism include: Impact: Applications should articulate the short- and long-term impact of the proposed research on both the SCI research field as well as the SCI community. Projects must address one or more of the FY24 SCIRP Focus Areas. Relevance to Military Health: Projects should be relevant to spinal cord-injured military Service Members, Veterans, and/or their Family members and care partners. Collaboration with military and VA researchers and clinicians is encouraged. Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinicians first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and support the proposed research project.IIRA applications may focus on any phase of research from basic through translational, though studies focused exclusively on target identification are discouraged. Permitted research includes preclinical studies in animal models (except where otherwise specified), research with human subjects or human anatomical substances, as well as ancillary studies associated with an existing clinical trial.

Science and Technology
Nonprofits
BJA FY25 Prison Rape Elimination Act (PREA) Training Curriculum for New Corrections Staff
$1,750,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Feb 24, 2025

Date Added

Jan 2, 2025

This funding opportunity provides resources to develop a standardized training curriculum for new corrections staff to effectively prevent and respond to sexual abuse and harassment in various confinement facilities across the country.

Law Justice and Legal Services
Public and State controlled institutions of higher education
NIAID New Innovators Awards (DP2 Clinical Trial Not Allowed)
$300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

Jun 2, 2023

This funding opportunity supports early-stage researchers in the U.S. who are pursuing innovative and high-impact projects in infectious, immunologic, and allergic diseases, without requiring extensive preliminary data.

Health
State governments
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2025

Date Added

Dec 22, 2023

This funding opportunity supports early stage researchers in pursuing innovative and high-risk scientific projects that significantly diverge from their previous work, without the need for preliminary data.

Education
State governments
Investigator Initiated Extended Clinical Trial (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 15, 2025

Date Added

Jan 12, 2023

This funding opportunity supports long-term, investigator-led clinical trials aimed at advancing research in allergy, infectious diseases, and aging, available to a wide range of eligible institutions both in the U.S. and internationally.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Novel Preclinical Models of NeuroHIV in the cART Era (R61/R33 - Clinical Trial Not Allowed)
$750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2024

Date Added

Mar 22, 2024

The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with the National Institute of Mental Health (NIMH), intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications that propose the development and early stage validation of novel humanized small animal models and/or human cellular microphysiological systems for NeuroHIV preclinical research. The goal of this initiative is to promote a significant improvement in the translational relevance of NeuroHIV models, specifically in the context of chronic HIV infection of the central nervous system (CNS) in the modern antiretroviral therapy (ART) era under conditions of viral suppression. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Summer 2024 with an expected application due date in Fall 2024. This NOFO will utilize the R61/R33 activity code. Details of the planned NOFO are provided below.

Health
State governments
DRL Advancing Freedom of Association and Improving Workers' Rights in Indonesia's Palm Oil Sector
$800,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Jul 8, 2024

Date Added

May 24, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in advancing freedom of association and improving working conditions in the palm oil sector in Indonesia.

International Development
Nonprofits
Organs-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 19, 2024

Date Added

Sep 10, 2024

This funding opportunity supports researchers and institutions developing innovative organ-on-a-chip technologies to advance disease modeling and preclinical studies in dental, oral, and craniofacial health.

Health
State governments
Strengthening Integrated Health Services Activity (SIHSA)
$45,000,000
USAID-GUI (Guinea USAID-Conakry)
Federal

Application Deadline

May 15, 2024

Date Added

Mar 14, 2024

The United States Agency for International Development (USAID) is seeking applications for a Cooperative Agreement with a Total Estimated Amount of $45,000,000 from qualified entities to implement the program entitled Strengthening Integrated Health Services Activity (SIHSA) in Sierra Leone.USAID anticipates awarding a five-year cooperative agreement (CA) to advance and sustain improved health outcomes for Sierra Leoneans with a focus on, but not limited to: children under five, pregnant and postpartum women, youth and especially adolescent girls, and women and children living in hard-to-reach areas with limited access to health services. Special attention will be paid to those especially vulnerable within these groups, such as the disabled, gender andsexual minorities (GSM), and ethnic and religious minorities.SIHSA seeks to build a sustainable and resilient health system response to improving access, quality, and effectiveness of family planning (FP), reproductive health (RH), maternal, newborn and child health (MNCH), adolescent health, and malaria services. In addition, SIHSA aims at strengthening communities;apos; active engagement for community-driven solutions to improve health outcomes. Finally, SIHSA seeks to promote a paradigm shift within the health system, supporting system-wide action, especially at community and district levels, including reforms that act on the foundations of the health system and create opportunities for partnering with the local civil society and private sector for improved health outcomes.

Health
Individuals
Alzheimers Research Program Transforming Diagnosis Award
$1,700,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 29, 2025

Date Added

Apr 21, 2025

This funding opportunity supports innovative research projects that improve the early diagnosis and prognosis of Alzheimer’s disease and related dementias, emphasizing community collaboration and inclusivity for underrepresented populations.

Science and Technology
Nonprofits