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Grants for Small businesses - Federal

Explore 1,854 grant opportunities

Advancing Research to Understand Congenital Malformations (R01 Clinical Trial Not Allowed)
$499,999
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2024

Date Added

Aug 9, 2022

This grant provides funding for researchers to investigate the genetic and environmental causes of structural birth defects, promoting collaboration between scientists and clinicians to improve prevention and treatment strategies.

Health
State governments
Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Administrative Resource Core (U24) (Clinical Trial Optional)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research projects focused on understanding the brain and body mechanisms that contribute to excessive alcohol consumption and Alcohol Use Disorder, encouraging innovative approaches and partnerships among researchers.

Health
State governments
ROSES 2024: C.22 Precursor Science Investigations for Europa
$2,500,000
NASA-HQ (NASA Headquarters)
Federal

Application Deadline

Jul 11, 2024

Date Added

May 21, 2024

Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

Science and Technology
Nonprofits
DoD Melanoma, Focused Program Award Rare Melanomas
$2,800,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 1, 2025

Date Added

May 27, 2025

This grant provides funding for multidisciplinary research teams to investigate and develop treatments for rare types of melanoma, aiming to improve prevention, early intervention, and quality of life for patients.

Science and Technology
Nonprofits
Future Manufacturing
$3,000,000
National Science Foundation
Federal

Application Deadline

Jun 18, 2025

Date Added

May 16, 2025

This grant provides funding for innovative research projects that aim to transform manufacturing processes in the U.S. by addressing scientific, technological, and educational challenges, while promoting workforce development and inclusivity in STEM fields.

Science and Technology
Nonprofits
Epilepsy Incidence Among Children in the United States
$500,000
U.S. Department of Health & Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Jan 23, 2025

Date Added

Nov 7, 2024

This funding opportunity provides financial support for eligible organizations to research and analyze the incidence of epilepsy among children in the U.S., focusing on disparities and risk factors using advanced data science techniques.

Health
State governments
Strengthening Teamwork for Robust Operations in Novel Groups (STRONG)
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Jan 31, 2025

Date Added

Dec 11, 2024

This program provides funding to researchers and organizations to develop innovative technologies that improve teamwork between humans and intelligent agents in military operations.

Safety
Public and State controlled institutions of higher education
Request For Information Mutually Beneficial Multidisciplinary Innovation Ecosystems
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Mar 17, 2026

Date Added

Dec 18, 2025

This grant seeks to foster collaborative research partnerships between U.S.-based universities, research institutions, and the Army to accelerate the development and integration of advanced technologies for national defense.

Science and Technology
City or township governments
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 13, 2025

Date Added

Apr 18, 2024

This grant provides funding for research on behavioral sleep interventions aimed at improving sleep and mental health outcomes for adolescents and young adults, particularly those from underserved populations.

Health
State governments
Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed)
$400,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 10, 2024

Date Added

Sep 27, 2024

This funding opportunity provides financial support for research sites to study Type 1 diabetic nephropathy by recruiting patients, conducting kidney biopsies, and collecting data to identify new treatment targets and improve precision medicine approaches.

Food and Nutrition
State governments
Grants to Support New Investigators in Conducting Research Related to Preventing Interpersonal Violence and Suicide Among Children and Youth (K01)
$150,000
U.S. Department of Health & Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Jun 22, 2026

Date Added

May 1, 2024

This funding opportunity supports early-career researchers in developing independent studies aimed at preventing violence and suicide among children and youth, with a focus on practical applications and community impact.

Health
Public and State controlled institutions of higher education
Continuation of the NIDDK Hematology Central Coordinating Center (U24 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 18, 2025

Date Added

Dec 17, 2024

This funding opportunity supports a central coordinating center that will enhance collaboration and provide resources for research in nonmalignant hematology, particularly aimed at fostering the development of junior investigators and innovative projects across multiple institutions.

Food and Nutrition
State governments
DoD VRP, Translational Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Nov 8, 2024

Date Added

May 17, 2024

This grant provides funding for researchers to develop and test new treatments or technologies aimed at preventing and addressing eye injuries and visual dysfunction related to military service.

Science and Technology
Nonprofits
Targeting Inflammasomes in HIV and Substance Use (R21 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 13, 2025

Date Added

Oct 30, 2024

This funding opportunity provides financial support for research on the role of inflammasomes in the brain related to HIV and substance use disorders, targeting innovative studies that explore their impact on inflammation and neurocognitive health.

Education
State governments
BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

Feb 16, 2024

This grant provides funding for interdisciplinary research teams to explore the ethical implications of new neurotechnologies and brain science advancements, focusing on issues like data privacy, informed consent, and public attitudes toward brain research.

Education
State governments
Closing inequities in HIV Prevention, Care and Treatment among key populations in Burkina Faso Activity (Equity KP Burkina Faso)
$5,000,000
U.S. Agency for International Development (West Africa USAID-Ghana)
Federal

Application Deadline

Oct 13, 2024

Date Added

Aug 22, 2024

The "Closing inequities in HIV Prevention, Care and Treatment among key populations in Burkina Faso Activity (Equity KP Burkina Faso)" grant aims to support local entities in Togo and Burkina Faso in providing quality HIV services, improving the environment for key populations and their partners, and enhancing monitoring and sustainability efforts for HIV epidemic control by 2030.

Health
Individuals
FY 2025 Phase I Release 1
$250,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Oct 8, 2024

Date Added

Aug 5, 2024

The "FY 2025 Phase I Release 1" grant is a funding opportunity provided by the Department of Energy (DOE) for small businesses to conduct innovative research or development projects that have commercial potential and support the DOE's mission, with successful Phase I grantees eligible to apply for further support in Phase II.

Science and Technology
Small businesses
NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 26, 2023

This funding opportunity supports organizations conducting large-scale clinical trials focused on innovative treatments for vision disorders, ensuring effective management and oversight of the research process.

Health
State governments
Forecast for NIH Blueprint and BRAIN Initiative ACTION Potential Program (F99/K00 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 20, 2026

Date Added

May 28, 2025

This funding opportunity supports neuroscience graduate students in completing their doctoral studies and transitioning to postdoctoral research positions, fostering their development into independent investigators in the field.

Health
State governments
NIH Directors Transformative Research Awards (R01 Clinical Trial Optional)
$8,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 3, 2025

Date Added

May 13, 2025

This funding opportunity supports innovative researchers and teams in the U.S. who propose groundbreaking projects that could significantly advance biomedical and social sciences, without the need for preliminary data.

Health
State governments