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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Alzheimer's Disease Research Centers (P30 Clinical Trial Not Allowed)
$2,925,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2025

Date Added

Jan 11, 2023

This funding opportunity provides financial support to higher education institutions and nonprofits to establish or renew research centers focused on advancing studies related to Alzheimer's disease and related dementias, promoting collaboration, innovation, and diversity in research efforts.

Health
State governments
BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

Feb 16, 2024

This funding opportunity supports short-term research projects that explore the ethical challenges arising from advancements in neurotechnology and brain science, encouraging collaboration between ethicists and neuroscientists.

Health
State governments
FY25 NOAA Marine Debris Interception Technologies under the Bipartisan Infrastructure Law
$1,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Feb 7, 2025

Date Added

Jul 26, 2024

This funding opportunity provides financial support for projects that install and maintain technologies to intercept and remove marine debris, benefiting coastal habitats and marine resources.

Environment
State governments
Exponentiating Mathematics (expMath)
Contact for amount
U.S. Department of Defense (DARPA - Information Innovation Office)
Federal

Application Deadline

Jul 15, 2025

Date Added

May 14, 2025

This funding opportunity seeks innovative research proposals from universities, businesses, and nonprofits to develop advanced AI technologies that can significantly accelerate mathematical progress and enhance national competitiveness.

Science and Technology
City or township governments
Novel AI Techniques for Insights
$2,000,000
Department of Defense (DoD)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2025

This funding opportunity is designed for small businesses to develop innovative AI technologies that analyze large datasets for detecting anomalies and patterns, ultimately improving decision-making across various sectors.

Science and Technology
Small businesses
Closing inequities in HIV Prevention, Care and Treatment among key populations in Togo Activity (Equity KP Togo)
$5,000,000
U.S. Agency for International Development (West Africa USAID-Ghana)
Federal

Application Deadline

Oct 13, 2024

Date Added

Aug 22, 2024

The "Closing inequities in HIV Prevention, Care and Treatment among key populations in Togo Activity (Equity KP Togo)" grant aims to support local entities in Togo and Burkina Faso in providing quality HIV services, improving the environment for key populations and their partners, and enhancing monitoring and sustainability efforts for HIV epidemic control by 2030.

Health
Individuals
Spinal Cord Injury Research Program Clinical Trial Award
$14,560,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 30, 2024

Date Added

Mar 26, 2024

The SCIRP CTA supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of SCI. Applications should articulate both the short- and long-term impact of the proposed research on individuals with SCI and/or their care partners. The proposed intervention(s) to be tested should offer significant potential impact for individuals affected by SCI within the context of one or more of the FY24 SCIRP Focus Areas. The U.S. Army Medical Research Acquisition Activity (USAMRAA) is soliciting applications to the Fiscal Year 2024 (FY24) Spinal Cord Injury Research Program (SCIRP) using delegated authority provided by United States Code, Title 10, Section 4001 (10 USC 4001). The Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC) is the program management agent for this funding opportunity. Congress initiated the SCIRP in 2009 to provide support for traumatic spinal cord injury (SCI)-related research of exceptional scientific merit that has the potential to make a significant impact on improving the health and well-being of military Service Members, Veterans, and other individuals living with SCI. Appropriations for the SCIRP from FY09 through FY23 totaled $437.85 million (M). The FY24 Defense Appropriations Act provides $40M to the SCIRP through the appropriation for peer-reviewed spinal cord research. The vision of the SCIRP is to advance the treatment and management of SCI and ameliorate its consequences. The FY24 SCIRP challenges the scientific community to design research that will advance the development or translation of health care solutions for people living with SCI. Innovative research that fosters new directions or addresses neglected issues in the field of traumatic SCI is also supported, although studies focused exclusively on target identification are discouraged. The SCIRP encourages impactful research across the continuum of care from time of injury and across the life span that is well reasoned and scientifically supported. Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, their Families and/or care partners.

Science and Technology
Nonprofits
NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Mar 3, 2023

This funding opportunity supports U.S. institutions in developing educational programs for psychiatry residents to enhance their research skills and encourage careers in mental health research.

Health
State governments
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens
$4,500,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Nov 6, 2024

This funding opportunity provides financial support to a wide range of organizations, including governments, educational institutions, and nonprofits, to enhance surveillance and detection of antibiotic resistance in food products, ultimately improving public health and food safety.

Consumer Protection
State governments
F26AS00007-NAWCA 2026 US Small Grants
$250,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Jun 25, 2026

Date Added

Apr 21, 2026

This grant provides funding to a wide range of organizations and individuals for projects that protect and restore wetlands and habitats for migratory birds and other wildlife across the United States.

Natural Resources
State governments
NINR Mentoring Resources and Activities
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 27, 2026

Date Added

May 29, 2025

This funding opportunity supports projects that provide mentoring and career development for nurse scientists to enhance their professional growth and increase the number of nurse researchers with NIH-funded projects.

Health
County governments
Transforming Pediatrics for Early Childhood (TPEC) Program
$4,750,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Jul 10, 2026

Date Added

Mar 16, 2026

This funding opportunity provides financial support to various organizations for integrating early childhood development experts into pediatric practices, enhancing healthcare for young children, particularly those from low-income families.

Health
State governments
DoW Peer Reviewed Medical, Lifestyle and Applied Health Research Award
$4,200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This funding opportunity provides substantial financial support for clinical research projects that focus on nonpharmacological health interventions and improve the well-being of Service Members, Veterans, and their families through patient-centered care.

Health
Nonprofits
DoD Kidney Cancer, Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 15, 2024

Date Added

Jul 12, 2024

The DoD Kidney Cancer, Idea Development Award is a funding opportunity aimed at supporting innovative, high-impact kidney cancer research projects, with a focus on scientific rationale, preliminary data, innovation, and potential impact, and encourages collaborations among academia, industry, military services, and other federal agencies, with a budget not exceeding $800,000 for individual projects and $1.2M for partnered projects.

Science and Technology
Nonprofits
DRL Promoting an Inclusive West Africa (PIWA)
$1,250,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

May 7, 2024

Date Added

Mar 8, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights and Labor announces an open competition for organizations interested in submitting applications for a project to address the ethnic marginalization across Coastal West Africa. The U.S. Department of State, Bureau of Democracy, Human Rights and Labor (DRL) announces an open competition for organizations interested in submitting applications for a project to address the ethnic marginalization across Coastal West Africa. The consolidation of power, poor governance, and rise of violent extremism in some Coastal West African countries have contributed to the exclusion and discrimination of certain ethnic groups in politics and everyday life. While certain ethnic groups are not legally excluded from civic and political participation, their full engagement in decision-making roles remains limited. Certain ethnic groups are particularly marginalized in the government, the civil service, and the armed forces. Some ethnic groups also experience discrimination in employment and access to credit, health care, and education. Hundreds of thousands of individuals, including migrants and rural-based members of society, lack documentation to obtain citizenship or access public resources despite protections under the law. In addition, certain ethnic groups face societal discrimination, including stigmatization, harassment, and attacks. Militant groups have exploited the marginalization of certain ethnic groups by playing on grievances and amplifying 2 feelings of distrust in government to recruit members. For example, the targeting of Fulbe communities—based on the belief that they all support jihadi insurgents—has perpetuated conflict, facilitated jihadi recruitment, and risks spreading the violence into new areas. The property and land rights systems across Coastal West Africa has disenfranchised certain ethnic groups historically, causing violence to erupt at times. For example, pastoralist communities who have lived in certain areas for decades have faced the encroachment of agriculturalists on land that they typically use for grazing. In addition, governments across the region have introduced new laws and policies that limit pastoralists’ way of life. Further problematic is that the agencies in charge of developing new land rights policies and programs do not include members of the ethnic groups that would be heavily impacted by the changes. To respond to these challenges, DRL is seeking proposals with the goal of supporting members of marginalized communities in Coastal West Africa—specifically Ghana, Cote d’Ivoire, Benin, and /or Togo—to improve respect for their political rights and civil liberties. Proposals may focus on individual countries or multiple countries, but approaches must be led by, or have strong support from and participation by, groups and individuals representing marginalized ethnic groups. Proposals may include but do not need to support members of pastoralist communities. DRL recognizes that there are numerous other ethnic groups in the region that do not fully enjoy the rights enumerated by law. Applicants are encouraged to complement and deconflict with existing programs that address ethnic marginalization in the region. DRL seeks proposals for programming that are ambitious but also targeted and achievable. DRL will consider proposals that address the goal reflected above but include different, though similar and related, objectives. While proposals may include additional objectives, inclusion of additional objectives will not make a proposal more competitive.

International Development
Public and State controlled institutions of higher education
Air Dominance Broad Agency Announcement (BAA)
$750,000,000
U.S. Department of Defense (Munitions Directorate)
Federal

Application Deadline

Not specified

Date Added

Apr 15, 2025

This funding opportunity supports a wide range of research and development projects aimed at advancing technologies for national defense and air superiority, inviting participation from educational institutions, nonprofits, private industry, and small businesses.

Science and Technology
Small businesses
Integrated Health Initiative (IHI) Activity
$92,500,000
Agency for International Development (Afghanistan USAID-Kabul)
Federal

Application Deadline

Jan 24, 2025

Date Added

Dec 16, 2024

This funding opportunity is designed to improve access to quality health services for women and children in five provinces of Afghanistan, focusing on critical health issues such as maternal and newborn health, family planning, and nutrition.

Health
Nonprofits
Limited Competition: Small Grant Program for ORIP Special Emphasis Research Career Award (SERCA) K01 Recipients (R03 Clinical Trial Not Allowed)
$75,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 7, 2026

Date Added

Nov 19, 2024

This funding opportunity provides financial support to veterinary scientists who have received a specific career development award, helping them transition to independent research by enabling small-scale projects that build on their existing work.

Health
State governments
Master Announcement Instructions (MAI)
Contact for amount
Department of Health and Human Services - Advanced Research Projects Agency for Health
Federal

Application Deadline

Oct 20, 2024

Date Added

Jun 26, 2024

Amendment 1 (June 25, 2024): The purpose of this Amendment 1 is to: 1) make administrative updates to Section 1.1, 1.2, 2.1.2, 3.1, 3.2 and 5.2.6; 2) replace Section 2.1.1 with new language pertaining to Federally Funded Research and Development Centers (FFRDCs) and Government Entities. Additionally, Section 4.2, Evaluation Criteria #2 is updated to remove the reference to Government Entities (removal is not highlighted in yellow); 3) change references from Abstract to Solution Summaries (intent behind the document is unchanged); 4) update proposal submission instructions in Section 3.2; and 5) update Section 5.1 to remove the Stage 2 Notification Letter. All changes are highlighted in yellow.Also, please note that the title of this opportunity has bee revised to eliminate confusion. The opportunity should have been titled, "Master Announcement Instruction (MAI)" instead of "ARPA-H BDF Tool Box".The Master Announcement Instructions (MAI) is a new ARPA-H announcement that aims to create standard tiered proposal submission requirements, so the amount of work required to write a proposal is commensurate with the size of the proposed effort. It also aims to reduce the up-front work required to submit cost information to reduce the barrier to entry for non-traditional performers. Module announcements that link to this MAI will provide more specific instructions about how the proposal requirements vary across tiers of effort.All responsible sources capable of satisfying the Governments needs may submit a proposal to a Module Announcement. Specifically, universities, non-profit organizations, small businesses and other than small businesses are eligible and encouraged to propose to Module Announcements.NOTE: Proposals shall NOT be submitted against the MAI. Proposals shall only be submitted against a Module Announcement.

Health
Public and State controlled institutions of higher education
Delta Health Systems Implementation Program
$2,020,000
HHS-HRSA (Health Resources and Services Administration)
Federal

Application Deadline

May 21, 2024

Date Added

Apr 5, 2024

The purpose of the Delta Health Systems Implementation Program (DSIP) is to improve healthcare delivery in rural areas by implementing projects that will improve the financial sustainability of hospitals and allow for increased access to care in rural communities. These projects focus on financial and operational improvement, quality improvement, telehealth, and workforce development in hospitals in the in the rural counties and parishes of the Delta region. This program supports HRSA's collaboration with the Delta Regional Authority.

Health
State governments