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Grants for Small businesses - Federal

Explore 1,517 grant opportunities

BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This grant provides funding for researchers and organizations to develop innovative technologies that can record and manipulate neural activity in the nervous system, with a focus on enhancing precision and scalability in studies involving animals or humans.

Health
State governments
Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
$1,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 31, 2024

This funding opportunity supports preclinical research to identify and test existing drugs or drug combinations for their potential to treat Alzheimer’s Disease and related dementias, encouraging collaboration between academic and industry partners.

Health
State governments
Neural Ensembles Used Substances (NExUS) Collaboratory : Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances
$700,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 2, 2026

Date Added

Sep 12, 2025

This grant provides funding for a diverse range of organizations to conduct collaborative research on how neural cell populations are affected by addictive substances, aiming to improve understanding of addiction mechanisms.

Health
City or township governments
Perception, Action Cognition
$715,000
National Science Foundation
Federal

Application Deadline

Aug 3, 2026

Date Added

Apr 17, 2025

This funding opportunity supports researchers investigating human perception, action, and cognition, encouraging innovative studies that have practical societal benefits.

Science and Technology
Individuals
Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research into the biological mechanisms behind complex brain disorders, targeting institutions and organizations that can investigate genetic and environmental risk factors to advance therapeutic interventions.

Health
State governments
Small Business Innovation Research (SBIR) program, Phase I
$100,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support to small businesses for innovative research and development projects that aim to improve the quality of life for individuals with disabilities.

Science and Technology
Small businesses
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 16, 2025

This funding opportunity supports collaborative research teams in developing innovative drugs and devices to improve treatments for mental health disorders.

Health
State governments
Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity supports U.S. organizations in developing and optimizing medical devices and diagnostics aimed at addressing significant health challenges related to heart, lung, blood, and sleep diseases.

Health
State governments
Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access (X01, Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This grant provides access to specialized resources and expertise for researchers developing gene-based therapies for ultra-rare neurological and neuromuscular diseases, helping them advance their projects toward regulatory approval.

Health
State governments
The Conservation Stewardship Program
Contact for amount
USDA Natural Resources Conservation Service
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 16, 2025

This program provides financial rewards to agricultural producers in Montana who implement conservation practices that improve natural resources while maintaining land productivity.

Agriculture
Individuals
Archiving and Documenting Child Health and Human Development Data Sets (R03 Clinical Trial Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports higher education institutions, non-profits, government entities, and small businesses in archiving and enhancing child health and human development datasets to promote secondary research and data accessibility.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Morris K. Udall Discovery Centers without Walls (DCWoW) for Parkinson's Disease Research (RM1 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 28, 2025

This funding opportunity supports collaborative biomedical research initiatives aimed at uncovering the causes of Parkinson's disease, inviting a wide range of eligible applicants, including universities, nonprofits, and private organizations, to develop innovative projects.

Health
State governments
In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 7, 2025

This funding opportunity supports the development of advanced imaging technologies for the inner ear to improve diagnosis and treatment of hearing and balance disorders, targeting researchers and institutions with expertise in medical imaging and related fields.

Health
State governments
Unveiling Health and Healthcare Disparities in Non-Communicable and Chronic Diseases in Latin America: Setting the Stage for Better Health Outcomes Across the Hemisphere (R01 - Clinical Trials Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 9, 2025

This funding opportunity supports collaborative research projects aimed at addressing health disparities in non-communicable diseases among underserved populations in Latin America and U.S. Hispanic and Latino communities.

Education
State governments
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
$1,515,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 6, 2024

This funding opportunity supports early-phase clinical trials for innovative treatments and diagnostics targeting heart, lung, blood, and sleep disorders in both adults and children, encouraging diverse participation and addressing unmet medical needs.

Health
State governments
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Jul 30, 2025

This funding opportunity supports innovative research on how human behaviors impact oral and systemic health in individuals with chronic conditions, encouraging collaborations among experts in health and social sciences.

Health
Public housing authorities
Astronomy and Astrophysics Research Grants
$50,000,000
National Science Foundation
Federal

Application Deadline

Nov 15, 2026

Date Added

Nov 25, 2024

This funding opportunity supports U.S.-based researchers and teams in advancing studies and projects in astronomy and astrophysics, including observational, theoretical, and educational initiatives.

Science and Technology
Public and State controlled institutions of higher education
Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity supports the early-stage development of medical devices and diagnostics aimed at addressing heart, lung, blood, and sleep disorders, targeting higher education institutions, nonprofits, small businesses, and local governments.

Health
State governments
Notice of Intent to Publish a Forecast for EmbraceHealth Clinical Research Network to Reduce Health Disparities Research Sites
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity is designed to support a network of research sites that will develop and implement interventions to address health disparities affecting underserved and marginalized populations across the United States.

Health
Private institutions of higher education
Dementia Care and Caregiver Support Intervention Research - Stage I Only
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity supports early-stage research projects that develop behavioral interventions for individuals living with Alzheimer’s disease and their caregivers, encouraging diverse organizations to enhance dementia care and support.

Health
State governments