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Grants for Small businesses - Federal

Explore 1,517 grant opportunities

Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required) FOR-HL-25-018
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Aug 5, 2025

This funding opportunity is designed to support organizations that will manage and coordinate data for multi-site clinical trials focused on heart, lung, and blood diseases, encouraging collaboration among various research institutions.

Health
Independent school districts
Broad Agency Announcement for Fundamental AI Research
Contact for amount
U.S. Department of Defense (Army Contracting Command Rock Island)
Federal

Application Deadline

Not specified

Date Added

Apr 17, 2025

This funding opportunity invites universities, non-profits, and for-profit organizations to propose innovative research in artificial intelligence that enhances military capabilities and decision-making processes.

Science and Technology
Public and State controlled institutions of higher education
Rare Diseases Are Not Rare! 2025 Challenge
$3,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This competition invites artists, researchers, and advocates to create innovative media that raises awareness and promotes collaborative treatment strategies for the millions affected by rare diseases in the U.S.

Health
Individuals
Novel Experiential Technologies Assisting Individual Learning (NExT AI) Hubs
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 4, 2026

Date Added

Jul 9, 2025

This funding opportunity supports research centers focused on exploring how innovative artificial intelligence technologies can improve learning outcomes for children with specific learning disabilities affecting literacy and numeracy skills.

Health
For profit organizations other than small businesses
Research on System Support and Tools for Provider Training and Quality Monitoring for Suicide Preventive Care
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 18, 2025

This funding opportunity provides financial support for organizations to develop and evaluate tools that improve training and quality monitoring for healthcare providers delivering suicide prevention care.

Health
County governments
Forecast to Publish a Funding Opportunity Announcement for Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project Sites (U01 Clinical Trials Optional)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 14, 2025

This funding opportunity is designed to support existing research sites studying the impact of adolescent alcohol exposure on brain development and long-term health outcomes.

Health
State governments
Elder Justice Innovation Grants FY2026
$500,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

May 5, 2026

Date Added

Sep 8, 2025

This funding opportunity provides financial support to U.S.-based organizations working on innovative projects to prevent and address elder abuse, neglect, and exploitation, with a focus on creating resources that can be widely shared and implemented.

Income Security and Social Services
Nonprofits
2025 "$100,000 Start an SUD Startup" Challenge
$10,000
U.S. Department of Health and Human Services (National Institute on Drug Abuse)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This grant provides funding and mentorship to interdisciplinary teams developing innovative solutions for drug use and substance use disorders, aiming to support the formation of early-stage biotech startups in the U.S.

Health
Individuals
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 21, 2024

This funding opportunity supports multi-site clinical trials and biomarker studies aimed at improving stroke treatment, recovery, and prevention, encouraging collaboration with the NIH StrokeNet infrastructure.

Health
State governments
Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity supports a collaborative research initiative aimed at improving cardiovascular health outcomes through innovative surgical techniques and technologies, inviting participation from a diverse range of organizations, including universities, nonprofits, and businesses.

Health
Public and State controlled institutions of higher education
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 3, 2024

This funding opportunity supports researchers in developing innovative screening methods and therapies for newborn disorders to improve early detection and treatment outcomes.

Health
State governments
Clinical Research Network on Antimicrobial Resistance
$15,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 29, 2026

Date Added

Dec 30, 2025

This funding opportunity supports research institutions and organizations in developing innovative solutions to combat antimicrobial resistance, particularly for vulnerable populations facing serious infections.

Health
City or township governments
Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers
$55,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 13, 2025

This funding opportunity supports research centers focused on improving the prevention and management of multiple chronic diseases, particularly in underserved populations, by encouraging innovative and collaborative projects.

Health
Private institutions of higher education
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 19, 2025

This funding opportunity provides financial support to small businesses in the U.S. for innovative research and development projects that advance health and biomedical innovation without involving clinical trials.

Health
Small businesses
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 3, 2025

This funding opportunity supports researchers exploring the ethical, legal, and social implications of genetic and genomic research, encouraging innovative studies that address real-world issues in these fields.

Education
State governments
Single Source: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Renal and Environmental Science Core (U01-Clinical Trial Not Allowed)
$1,750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 6, 2026

This funding opportunity provides $1.75 million to support research institutions and organizations investigating the causes and impacts of chronic kidney disease linked to environmental factors in agricultural communities, both in the U.S. and internationally.

Health
State governments
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 11, 2025

This grant provides funding to U.S. small businesses that have received prior SBIR or STTR Phase II awards, helping them advance their projects towards commercialization by supporting late-stage research and development activities.

Health
Small businesses
Nonprofit Security Grant Program
$210,000,000
Department of Homeland Security
Federal

Application Deadline

Not specified

Date Added

Oct 3, 2024

This funding opportunity provides financial support to nonprofit organizations, especially faith-based groups, to improve their security measures against targeted violence and hate crimes.

Safety
Nonprofits
Learning Collaborative for HIV Oral Health and Primary Care Integration
$600,000
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity provides financial support to organizations focused on improving oral health services for low-income individuals living with HIV by promoting the integration of dental care and primary HIV care through a collaborative learning approach.

Health
Public and State controlled institutions of higher education
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research into how certain diabetes medications may influence cancer risk, targeting institutions and organizations capable of conducting innovative studies in this area.

Education
State governments