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Grants for Small businesses - Federal

Explore 1,517 grant opportunities

Title V Competitive Sexual Risk Avoidance Education
$450,000
U.S. Department of Health & Human Services (Administration for Children ; Families - ACYF/FYSB)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This grant provides funding to local organizations in underserved states and territories to implement educational programs that encourage youth aged 10 to 19 to avoid non-marital sexual activity and promote healthy life choices.

Youth
Nonprofits
Rural Energy for America Program (REAP) : Renewable Energy Systems Grant
$1,000,000
U.S. Department of Agriculture (Rural Development)
Federal

Application Deadline

Not specified

Date Added

Feb 1, 2024

This program provides financial assistance to farmers and small rural businesses for implementing renewable energy projects and improving energy efficiency.

Energy
Small businesses
Core Centers for Clinical Research (CCCR) (P30 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2026

Date Added

Jun 13, 2025

This funding opportunity is designed to support research centers that develop innovative methods and metrics to improve clinical research in musculoskeletal, rheumatic, and skin diseases, emphasizing collaboration and community involvement.

Health
State governments
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
$1,515,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 6, 2024

This funding opportunity supports researchers conducting early-phase clinical trials to develop new treatments and diagnostic tools for heart, lung, blood, and sleep disorders in both adults and children.

Health
State governments
Spinal Cord Injury Model Systems Centers
$640,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Apr 24, 2026

Date Added

Sep 8, 2025

This funding opportunity supports organizations that provide comprehensive rehabilitation care for individuals with spinal cord injuries, enabling them to conduct research and contribute to a national database for improved clinical practices and outcomes.

Health
State governments
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Contact for amount
National Institute of Mental Health (NIMH)
Federal

Application Deadline

Not specified

Date Added

Apr 18, 2025

This funding opportunity supports partnerships between academic institutions and industry to develop new drugs and devices for treating mental health disorders, encouraging innovative research and early clinical trials.

Health
Public and State controlled institutions of higher education
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional) - PAR-25-032
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports research projects that help refine the design of future clinical trials focused on heart, lung, blood, or sleep disorders, encouraging participation from diverse and underrepresented groups.

Health
State governments
Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports a national resource for clinician-investigators focused on aging research, promoting collaboration, mentorship, and interdisciplinary projects to improve care for older adults.

Health
State governments
Assessing the Feasibility of Incorporating Mechanisms in Multisite Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2026

Date Added

Jul 9, 2025

This funding opportunity supports multisite studies that explore how mind and body interventions, like meditation and yoga, can improve overall health and emotional well-being, emphasizing the importance of understanding the mechanisms behind these effects.

Health
State governments
NLM Research Grants in Biomedical Informatics and Data Science (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 21, 2025

This funding opportunity supports innovative research projects that advance biomedical informatics and data science, aimed at improving health outcomes through data-driven discovery and technology integration.

Education
State governments
Molecular, Neural, and Cognitive Mechanisms of Non-Invasive Brain Stimulation to Treat Substance Use Disorders
$3,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

May 29, 2025

This funding opportunity supports research on non-invasive brain stimulation techniques to better understand and treat substance use disorders, encouraging collaboration among institutions and experts in addiction science.

Health
Nonprofits
Forecast to Publish a Funding Opportunity Announcement for Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 3, 2025

This funding opportunity supports the development of innovative informatics tools to improve cancer research and management, inviting a wide range of organizations to create user-friendly technologies that enhance data analysis and accessibility in the field.

Health
Native American tribal organizations
Rural Health Clinic Technical Assistance Program
$110,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Apr 17, 2026

Date Added

Dec 23, 2025

This program provides funding to organizations that will offer technical assistance to improve healthcare quality and delivery in rural health clinics across the United States.

Health
Nonprofits
National Ombudsman Resource Center
$520,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides resources and support to enhance the advocacy and operational capacity of state programs that protect the rights and well-being of residents in long-term care facilities across the United States.

Income Security and Social Services
Nonprofits
Research Opportunities in Crisis Response Services for Suicide Prevention
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity supports research projects that improve crisis response services for suicide prevention, targeting a wide range of organizations involved in mental health services and research.

Health
State governments
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity provides financial support for researchers and organizations developing innovative therapies for heart, lung, blood, and sleep disorders, focusing on early-stage product definition and validation.

Health
State governments
Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 9, 2025

This funding opportunity supports researchers in conducting real-world studies to evaluate the effectiveness of existing neurological treatments and interventions, particularly for underserved populations and health disparities.

Health
State governments