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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 2026

Date Added

Jun 11, 2025

This grant provides funding to U.S. small businesses with prior SBIR or STTR support to help advance their biomedical and health-related technologies toward market readiness and regulatory approval.

Health
Small businesses
Nonprofit Security Grant Program
$210,000,000
Department of Homeland Security
Federal

Application Deadline

Not specified

Date Added

Oct 3, 2024

This funding opportunity provides financial support to nonprofit organizations, especially faith-based groups, to improve their security measures against targeted violence and hate crimes.

Safety
Nonprofits
Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 5, 2026

Date Added

Jul 1, 2025

This funding opportunity supports research on the harmful effects of chemical exposures on skin, aiming to improve treatments and national preparedness for chemical emergencies, and is open to a wide range of eligible organizations, including universities and nonprofits.

Science and Technology
Public and State controlled institutions of higher education
Learning Collaborative for HIV Oral Health and Primary Care Integration
$600,000
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity provides financial support to organizations focused on improving oral health services for low-income individuals living with HIV by promoting the integration of dental care and primary HIV care through a collaborative learning approach.

Health
Public and State controlled institutions of higher education
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research into how certain diabetes medications may influence cancer risk, targeting institutions and organizations capable of conducting innovative studies in this area.

Education
State governments
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 31, 2024

This funding opportunity supports pilot research projects aimed at improving mental health services by generating preliminary data and exploring factors that affect access, quality, and outcomes, targeting a wide range of eligible applicants including educational institutions, nonprofits, and government organizations.

Health
State governments
Rehabilitation Research and Training Center (RRTC) On Employer Practices Leading to Successful Employment Outcomes Among People With Disabilities
$925,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This grant provides funding to various organizations to conduct research and training on effective employer practices that improve job opportunities for individuals with disabilities.

Employment Labor and Training
State governments
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for researchers and institutions to explore the brain's neural circuits related to mental health disorders through invasive techniques, fostering collaboration across various scientific fields to improve understanding and potential treatments.

Health
State governments
Kidney Precision Medicine Project Recruitment Sites (U01 Clinical Trial Not Allowed)
$4,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 5, 2026

Date Added

Sep 11, 2025

This funding opportunity supports various organizations in recruiting and managing participants with kidney diseases for a national study aimed at improving understanding and treatment of these conditions.

Health
Public and State controlled institutions of higher education
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This funding opportunity provides financial support for short-term clinical trials aimed at improving treatments for arthritis, musculoskeletal, and skin diseases, targeting researchers and institutions focused on innovative healthcare solutions.

Health
State governments
Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 16, 2025

This funding opportunity supports collaborative research projects that utilize existing biosamples and data from clinical studies on type 1 diabetes to enhance understanding of the disease and promote diverse research perspectives.

Food and Nutrition
State governments
Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports innovative research into the biological mechanisms of complex brain disorders, targeting early-stage projects that explore genetic and environmental risk factors affecting conditions like schizophrenia and depression.

Health
State governments
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports researchers investigating the biological and social factors behind neuropsychiatric symptoms in Alzheimer's disease to improve patient care and identify new treatment targets.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Infrastructure for Population Dynamics Research Program (iPOP) (P2C Clinical Trial Not Allowed)
$4,179,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 27, 2024

This funding opportunity provides financial support to a wide range of organizations to develop infrastructure that enhances research in population dynamics, focusing on demographic, economic, social, and health-related studies.

Health
Public and State controlled institutions of higher education
Screening for Conditions by Electronic Nose Technology (SCENT III) (Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Sep 30, 2025

This funding opportunity supports the development of noninvasive diagnostic technologies that utilize electronic nose systems to detect disease biomarkers, encouraging participation from a wide range of organizations, including governments, educational institutions, and nonprofits.

Health
State governments
Growing Great Ideas: Research Education Course in Product Development and Entrepreneurship for Life Science Researchers
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 1, 2026

Date Added

Sep 12, 2025

This funding opportunity is designed to equip researchers focused on substance use disorders with the entrepreneurial skills needed to turn their scientific discoveries into impactful products that benefit affected communities.

Health
Small businesses
DoW Tick-Borne Disease Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 22, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, treatment, and diagnosis of Lyme disease and other tick-borne diseases, targeting both established and early-career researchers.

Health
Nonprofits
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 6, 2024

This grant provides funding for researchers to develop and test innovative devices that diagnose and treat conditions affecting the nervous system in humans.

Education
State governments
Biology of Bladder Cancer (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 21, 2024

This funding opportunity supports innovative research to uncover the biological mechanisms of bladder cancer, inviting diverse teams to explore areas such as tumor development, microenvironment, and health disparities.

Education
State governments
Reflective Supervision in Home Visiting Research Awards
$330,000
U.S. Department of Health and Human Services (Administration for Children and Families - OPRE)
Federal

Application Deadline

Aug 3, 2026

Date Added

May 1, 2026

This funding opportunity provides financial support for research projects that explore and improve reflective supervision practices in early childhood home visiting programs, aimed at enhancing outcomes for families and home visitors.

Income Security and Social Services
State governments