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Grants for Small businesses - Federal

Explore 1,748 grant opportunities

Building National Partnerships for the Prevention of Emerging and Reemerging Infectious Diseases
$30,000,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCEZID)
Federal

Application Deadline

Not specified

Date Added

Oct 1, 2025

This funding opportunity provides substantial financial support to a wide range of organizations, including governments, nonprofits, and educational institutions, to enhance national efforts in preventing and responding to infectious disease threats across the United States.

Health
Nonprofits
Community Services Block Grant (CSBG) Essentials for Improved Outcomes
$600,000
U.S. Department of Health and Human Services (Administration for Children and Families - OCS)
Federal

Application Deadline

Aug 3, 2026

Date Added

Apr 28, 2026

This funding opportunity provides $600,000 to a single organization that will deliver training and technical assistance to improve the effectiveness of programs aimed at reducing poverty and supporting low-income communities across the U.S.

Income Security and Social Services
State governments
National Research Center for Promoting Work and Strong Families
$1,500,000
U.S. Department of Health and Human Services (Administration for Children and Families - OFA)
Federal

Application Deadline

Jul 16, 2026

Date Added

May 4, 2026

This funding opportunity provides financial support to a wide range of organizations for establishing a research center focused on improving employment, economic self-sufficiency, and family stability through evidence-based policy research and collaboration with policymakers.

Income Security and Social Services
State governments
DoW Vision, Clinical Trial Award
$2,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 4, 2026

This funding opportunity supports clinical trials aimed at improving the treatment and management of eye injuries and visual dysfunction in Service Members, Veterans, and their families.

Health
Nonprofits
Community Services Block Grant (CSBG) Tribal Capacity Building Training and Technical Assistance (TCBTTA)
$500,000
U.S. Department of Health and Human Services (Administration for Children and Families - OCS)
Federal

Application Deadline

Aug 3, 2026

Date Added

Apr 28, 2026

This funding opportunity provides financial support for an organization to deliver specialized training and technical assistance to tribal governments and organizations, helping them improve their capacity to serve low-income communities effectively.

Income Security and Social Services
Nonprofits
Extracellular Vesicle Therapeutics for Regenerative Medicine (ExTReMe)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity supports a wide range of organizations in developing innovative therapies using extracellular vesicles to advance regenerative medicine.

Health
Native American tribal organizations
Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 6, 2025

This funding opportunity provides financial support for short-term research training experiences for health professional and graduate students in biomedical, behavioral, or clinical research, helping them prepare for careers in scientific research.

Environment
State governments
Pilot Effectiveness Trials of Peer Support Services for Suicide Prevention
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 18, 2025

This funding opportunity supports research projects that evaluate peer support strategies for preventing suicide, targeting a wide range of eligible organizations, including universities, nonprofits, and government entities across the U.S.

Health
Public and State controlled institutions of higher education
The Experimental Therapeutics Clinical Trials Network (ETCTN) Lead Academic Organizations (UM1 Clinical Trial Required)
$11,800,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 30, 2026

Date Added

May 28, 2025

This funding opportunity supports academic organizations in the U.S. and Canada to lead early-phase cancer clinical trials, advancing innovative treatments and improving patient outcomes through collaborative research efforts.

Health
Public and State controlled institutions of higher education
Community Services Block Grant (CSBG) Communities of Practice (COP)
$725,000
U.S. Department of Health and Human Services (Administration for Children and Families - OCS)
Federal

Application Deadline

Aug 3, 2026

Date Added

Apr 28, 2026

This funding opportunity provides resources to organizations that support low-income individuals and families by enhancing training and technical assistance to improve economic security and service delivery systems across diverse communities in the U.S.

Income Security and Social Services
Nonprofits
NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
$6,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 18, 2026

Date Added

Mar 2, 2026

This funding opportunity supports the development of advanced diagnostic and therapeutic devices to address brain disorders and the opioid crisis, inviting a wide range of organizations, including universities, nonprofits, and businesses, to apply for resources to enhance their technologies for human use.

Health
Public and State controlled institutions of higher education
Silvio O. Conte Digestive Diseases Research Core Centers
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Sep 3, 2025

This grant provides funding to institutions with a strong foundation in digestive and liver disease research to foster collaboration and enhance innovative research through shared resources.

Health
State governments
NICHD Small Research Grant Program (R03 Clinical Trial Required)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports small-scale clinical trials focused on human development and health issues affecting children, adolescents, and individuals with intellectual disabilities, providing up to $50,000 for innovative research projects.

Health
State governments
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity supports researchers and organizations developing innovative drug therapies for Alzheimer's disease and related dementias, focusing on early-stage clinical trials to ensure safety and effectiveness.

Health
State governments
Novel AI Techniques for Insights
$2,000,000
Department of Defense (DoD)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2025

This grant provides funding for small businesses to develop innovative AI technologies that analyze large datasets for detecting anomalies and patterns, ultimately improving decision-making and operational efficiency across various sectors.

Science and Technology
Small businesses
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens
$4,500,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Nov 6, 2024

This funding opportunity provides financial support to a wide range of organizations, including governments, educational institutions, and nonprofits, to enhance surveillance and detection of antibiotic resistance in food products, ultimately improving public health and food safety.

Consumer Protection
State governments
Transforming Pediatrics for Early Childhood (TPEC) Program
$950,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Mar 16, 2026

This funding opportunity provides financial support to a wide range of organizations for implementing team-based early childhood development services within pediatric practices, focusing on improving health outcomes for young children and their families, particularly those enrolled in Medicaid and CHIP.

Health
Nonprofits
Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 13, 2025

This funding opportunity supports researchers in conducting innovative studies that build on existing clinical projects related to arthritis, musculoskeletal disorders, and skin diseases, without initiating new clinical trials.

Health
Public and State controlled institutions of higher education
Rural Health Network Advancement Program
$500,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Dec 12, 2025

This funding opportunity provides financial support to various organizations, including hospitals and community health centers, to collaborate and strengthen healthcare services in underserved rural areas, ensuring they can operate independently while improving access to care.

Health
Nonprofits
Growth Accelerator Fund Competition
$75,000
U.S. Small Business Administration (SBA)
Federal

Application Deadline

Not specified

Date Added

Jan 17, 2025

This funding opportunity supports organizations that help entrepreneurs in underserved areas by providing cash prizes to develop innovative solutions that enhance local business ecosystems.

Science and Technology
Nonprofits