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Grants for Small businesses - Federal

Explore 1,965 grant opportunities

Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites
$6,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Oct 1, 2025

This funding opportunity provides financial support to a diverse range of organizations for research on chronic kidney diseases in agricultural communities, focusing on participant recruitment, data collection, and collaborative studies to uncover the causes and potential interventions for this health issue.

Health
State governments
Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
$400,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 12, 2025

This funding opportunity provides financial support for innovative research studies aimed at improving understanding and treatment of rare diseases, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Health
Public and State controlled institutions of higher education
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 7, 2025

This funding opportunity supports clinical trials that develop and test new treatments for communication disorders, such as those affecting hearing, speech, and language, and is open to a wide range of eligible organizations, including universities and nonprofits.

Health
State governments
Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity supports institutions in training clinician-scientists to advance cancer research through structured mentorship and research programs.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for NIDA REI: Reaching Equity at the Intersection of HIV and Substance Use: Novel Approaches to Address HIV Related Health Disparities in Underserved Racial and/or Ethnic Populations (R01)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 26, 2024

This funding opportunity is designed to support innovative research projects that address health disparities related to HIV and substance use in underserved racial and ethnic communities.

Health
Small businesses
Alliance for Innovation on Maternal Health (AIM) Technical Assistance Center
$3,000,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Nov 13, 2026

Date Added

Aug 12, 2026

This grant provides funding to support technical assistance for improving maternal health outcomes across all states, territories, and tribal communities in the U.S.

Health
Nonprofits
Industrial Energy Storage Systems Prize
$400,000
U.S. Department of Energy (DOE)
Federal

Application Deadline

Not specified

Date Added

Oct 22, 2024

This competition provides $4.8 million in funding to encourage the development of innovative energy storage technologies that improve efficiency and reduce emissions in the U.S. industrial sector.

Energy
For profit organizations other than small businesses
Targeted Genome Editor Delivery (TARGETED) Challenge
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This grant provides funding to researchers and innovators developing advanced delivery systems for genome editing technologies, particularly targeting hard-to-reach tissues and overcoming the blood-brain barrier.

Science and Technology
For profit organizations other than small businesses
Science of Organizations
$3,270,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Feb 18, 2024

This program provides funding for researchers to explore and enhance the understanding of organizations across various sectors, focusing on theoretical contributions and rigorous methodologies.

Science and Technology
Public and State controlled institutions of higher education
Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports research to identify and develop treatments for central nervous system complications in people living with HIV, encouraging collaboration among diverse organizations and experts in related fields.

Health
State governments
New Investigator Grants to Conduct Research to Prevent Interpersonal Violence and Suicide Among Children and Adolescents (K01)
$150,000
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Dec 1, 2026

Date Added

Jul 3, 2026

This funding opportunity supports early-career researchers in developing projects that prevent violence and suicide among children and adolescents, with a focus on building their research skills and independence.

Health
State governments
Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2026

Date Added

Jun 18, 2025

This funding opportunity supports research to improve mental health interventions for older adults with serious mental illnesses, focusing on real-world applications in various care settings.

Health
Public and State controlled institutions of higher education
Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
Contact for amount
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 12, 2025

This funding opportunity supports clinical research aimed at developing new treatments for rare diseases, targeting a wide range of eligible organizations, including universities, nonprofits, and small businesses.

Health
Public and State controlled institutions of higher education
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This funding opportunity supports researchers conducting observational studies to improve understanding and treatment of musculoskeletal, rheumatic, and skin diseases, ultimately informing future clinical trials.

Health
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports research projects that involve clinical trials to improve health outcomes, targeting a wide range of eligible applicants including universities, nonprofits, and international organizations.

Education
State governments
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for researchers to study the neurobiological and behavioral mechanisms of mood and psychosis symptoms in women undergoing menopause, with the goal of developing new interventions and improving mental health outcomes.

Health
State governments
Improving Working Conditions in the Processing of Waste from Electrical and Electronic Equipment (E-Waste)
Contact for amount
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Not specified

Date Added

Apr 7, 2026

This initiative seeks insights from various stakeholders to improve labor conditions and promote decent work in the global e-waste processing sector, which involves millions of workers often in hazardous environments.

Employment Labor and Training
Nonprofits
Rural Communities Opioid Response Program - Community Systems Development
$500,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Apr 6, 2027

Date Added

Aug 17, 2026

This funding opportunity provides financial support to rural communities for developing and expanding behavioral health systems to effectively address substance use disorders through coordinated, evidence-based services.

Health
Nonprofits
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research projects that develop innovative and culturally responsive tools for measuring children's language development and identifying predictors of language impairments, with a focus on community engagement and inclusivity.

Health
State governments
AIM-AHEAD & NCATS Training Program
$10,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Not specified

Date Added

Sep 11, 2025

This program provides training and financial support for researchers from diverse backgrounds to learn how to analyze real-world clinical data using artificial intelligence and machine learning methods.

Health
Nonprofits