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Grants for Small businesses - Federal

Explore 1,965 grant opportunities

NIH Director's New Innovator Award (DP2 Clinical Trial Optional)
$475,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 19, 2027

Date Added

Sep 4, 2026

This grant provides funding to innovative early-stage researchers across various fields to support groundbreaking projects that have the potential to significantly advance scientific knowledge and health.

Health
State governments
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports researchers exploring how certain diabetes medications may affect cancer risk, focusing on innovative studies that investigate underlying biological mechanisms.

Education
State governments
NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System
$1,200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 8, 2026

This funding opportunity provides financial support for researchers and institutions to develop innovative gene-editing tools aimed at understanding and addressing neurological and neurodevelopmental disorders in the nervous system.

Health
State governments
Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports innovative research projects that explore the biological and genetic factors behind cancer health disparities, particularly among underserved racial and ethnic populations, encouraging early-career and underrepresented scientists to contribute to this critical field.

Education
State governments
Health and Extreme Weather Research Coordination and Data Center (U2C - Clinical Trial Not Allowed)
$3,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 29, 2027

Date Added

Jun 29, 2026

This funding opportunity is designed to establish a centralized hub for coordinating research and improving data access related to the health impacts of extreme weather events, targeting a wide range of eligible organizations including governments, educational institutions, and nonprofits.

Health
State governments
NIDCR Research Grants for Analyses of Existing Genomics Data (R01) (Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports researchers analyzing existing genomic data related to dental, oral, and craniofacial health, with a focus on addressing health disparities and identifying new intervention targets.

Health
State governments
Ryan White HIV/AIDS Program Part C Capacity Development Program
$150,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Mar 16, 2027

Date Added

Jul 14, 2026

This program provides funding to a wide range of organizations to strengthen their capacity to deliver effective HIV care and improve health outcomes for individuals living with HIV across the United States.

Health
State governments
Forecast to Publish a Funding Opportunity Announcement for EmbraceHealth Clinical Research Network to Reduce Health Disparities Coordinating Center
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity is designed to establish a Coordinating Center that will support research initiatives aimed at reducing health disparities in marginalized communities across the U.S. through effective clinical and behavioral interventions.

Health
State governments
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity supports innovative research on mood and psychotic disorders that may arise or worsen during the menopausal transition, targeting researchers and institutions focused on understanding and treating these conditions.

Health
State governments
Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 9, 2024

This funding opportunity supports research projects that develop and test non-drug interventions to improve sleep health and reduce sleep-related health disparities among underserved populations in the U.S.

Education
State governments
Advanced Technologies and Instrumentation for the Astronomical Sciences
$8,000,000
National Science Foundation
Federal

Application Deadline

Nov 15, 2026

Date Added

Aug 18, 2022

This funding opportunity supports researchers and institutions in developing innovative technologies and instruments to enhance ground-based astronomical observations and advance the field of astronomy in the U.S.

Science and Technology
Public and State controlled institutions of higher education
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports researchers analyzing existing genomic data related to dental, oral, and craniofacial health, particularly focusing on health disparities and genetic factors, with a goal of advancing knowledge in these areas.

Health
State governments
Disruptioneering Program
$2,000,000
Defense Advanced Research Projects Agency (DARPA)
Federal

Application Deadline

Not specified

Date Added

Mar 18, 2025

This funding opportunity is designed for researchers and organizations to explore and develop high-risk, high-reward technologies that can lead to innovative prototypes for national defense applications.

Science and Technology
For profit organizations other than small businesses
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports early-career researchers in dental, oral, and craniofacial science to develop preliminary data for future independent research projects.

Health
State governments
NIDA Core "Center of Transformative Science" Grant Program
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 8, 2026

This funding opportunity supports research centers that foster collaboration and innovation in the fields of substance use, addiction, and HIV, encouraging interdisciplinary approaches and career development for investigators across various organizations.

Health
State governments
Core Centers for Clinical Research (CCCR) (P30 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 13, 2025

This funding opportunity supports the establishment of research centers that enhance clinical study methods and community engagement in the fields of arthritis, musculoskeletal, rheumatic, and skin diseases.

Health
Public and State controlled institutions of higher education
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
$1,515,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 6, 2024

This funding opportunity supports researchers conducting early-phase clinical trials to develop new treatments and diagnostic tools for heart, lung, blood, and sleep disorders in both adults and children.

Health
State governments
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional) - PAR-25-032
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports research projects that help refine the design of future clinical trials focused on heart, lung, blood, or sleep disorders, encouraging participation from diverse and underrepresented groups.

Health
State governments
Assessing the Feasibility of Incorporating Mechanisms in Multisite Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 9, 2025

This funding opportunity supports multisite studies that explore how mind and body interventions, like meditation and yoga, can improve overall health and emotional well-being, encouraging collaboration among researchers in complementary health and clinical trial methodologies.

Health
State governments
NLM Research Grants in Biomedical Informatics and Data Science (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 21, 2025

This funding opportunity supports innovative research projects that advance biomedical informatics and data science, aimed at improving health outcomes through data-driven discovery and technology integration.

Education
State governments