Grants for Special district governments - Federal

This notice of funding opportunity (NOFO) will support development, adaptation, and/or applications of computational tools to aggregate and analyze orthogonal chemical and/or biological data sets related to natural products with the aim of generating novel testable hypotheses regarding their biological activity and role in the context of whole person health research. Projects must leverage and merge multiple compatible or interoperable sources and/or types of data. Use of artificial intelligence and machine learning approaches is encouraged. This NOFO is part of the Consortium Advancing Research on Botanicals and Other Natural Products (CARBON) Program. Other components of this Program include the Botanical Dietary Supplements Translational Research Teams (RM1) and Limited Competition: Research Resource for Natural Product Nuclear Magnetic Resonance Data (R24).

This grant provides funding to state and local governments, tribal organizations, and nonprofits for the recovery and preservation of historic sites damaged by natural disasters in 2023 and 2024.

This funding opportunity supports research on how sex differences influence the risk and treatment responses of Alzheimer's Disease and related dementias, inviting applications from a wide range of organizations, including universities, nonprofits, and businesses.

The Administration for Children and Families (ACF) plans to solicit applications for awards to support researchers conducting secondary analyses of data to address key questions of relevance to the Child Care and Development Fund (CCDF). CCDF is the primary federal funding source for child care subsidies and aims to help eligible low-income working families access child care and to improve the quality of child care for all children. CCDF also aims to improve implementation of high-quality child care programs to 1) promote childrens healthy development and learning and 2) support the education, training, and well-being of child care workers through efforts that include child care licensing, quality rating and improvement systems (QRIS) and professional development opportunities. Analyzing existing data sets may provide researchers an efficient and cost-effective method for answering critical research questions of relevance to CCDF. Findings from these awards are intended to inform policy, program administration, and future research.Topics of particular interest to ACF may include, but are not limited to: reducing barriers to access and/or improvements in access to child care and early education, particularly high-quality programs for those most in need of services; consumer education; recruiting and retaining a qualified early care and education (ECE) workforce; stabilizing the supply of high-quality care and education programs; improving teacher and caregiver competencies through professional development; supporting workforce well-being; and, approaches to engage, support, and meet the needs of families. Data sets of particular interest to ACF may include, but are not limited to, the 2019 National Survey of Early Care and Education and state- or territory-level workforce registry, subsidy, Quality Rating and Improvement System (QRIS), licensing, monitoring, Child Care Resource and Referral (CCR), or Preschool Development Grants B-5 data.

Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research. Background A major goal of the National Plan to address Alzheimer’s Disease (AD) and Alzheimer’s Disease-related Dementias (ADRD) is to reduce the burden of AD/ADRD by accelerating research toward treatments, improving care and support for people facing these conditions now, and reducing the risk of AD/ADRD by promoting brain health. Despite this, there is a shortage of scientists conducting the wide variety of necessary innovative and interdisciplinary research projects, including basic biomedical, clinical, translational, prevention, and treatment research on AD/ADRD. This Funding Opportunity Annoucnment (FOA) aims to address goal G-4 of the National Institute on Aging's Strategic Directions for Research (2020-2025): "Attract and train more researchers from diverse scientific and cultural backgrounds." This will include supporting the recruitment of a variety of early-stage investigators from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to the NIH AD/ADRD portfolio. This FOA also aims to address the lack of early exposure to high-quality, hands-on research education experiences in the AD/ADRD field, another major barrier to increasing the AD/ADRD capable workforce. To further expand the AD/ADRD training pipeline, NIA will support one-to-two-year intensive research experiences for recent baccalaureates, with a focus on receipt of mentorship for pursuing future research careers. The expectation is that such a program would help to transition the next generation of early-stage investigators into research careers representative of NIA mission critical areas, namely AD/ADRD research. Proposed programs should involve participants in independent research projects in AD/ADRD as it relates to aging. Participants will be required to work as research postbaccalaureates at nine person-months (75% full-time) effort, with the other three person-months (25% full-time effort) devoted to further academic and professional development. Academic development opportunities may include courses, seminars, or supplemental instruction that will enhance the technical, operational, and professional skills of the participants. Training in rigor and reproducibility is required. Professional development opportunities may include entrance exam preparation and conference and workshop participation. Program training objectives and mentoring activities should be grounded in literature and enable trainees to pursue advanced degrees and other research-related science career opportunities. Focus on Postbaccalaureates: Postbaccalaureate programs consist of studies pursued after the completion of one's bachelor’s degree, but before entering an advanced degree program, such as a master s, doctoral, or clinical degree program. The Association of American Medical Colleges (AAMC) reports an increased number of prospective medical students taking time off between the completion of their undergraduate education and enrollment in medical school. While students may take these gap years for a variety of reasons and be involved in a range of activities, almost half of such students report being involved in research during this time. Moreover, the COVID-19 pandemic has impacted students decisions to take gap years in a way that has been leading to a rise in the number of students taking this path. Literature shows that postbaccalaureate programs enable recent graduates to pursue advanced degrees and other research-related science career opportunities. For the purpose of this announcement, institutions should explain how this program will be developed in a way that will foster diversity and inclusion at their organization. As indicated below, applicants must include a Recruitment Plan to Enhance Diversity which describes the program’s proposed recruitment efforts and how the proposed plan reflects past experiences in recruiting individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences (see NOT-OD-20-031 for additional information on NIH's Notice of Interest in Diversity). All programs are expected to be inclusive, supportive, and safe, and to provide opportunities for participants to interact with investigators who could contribute to their growth. Applications from a variety of institutions, including those from minority serving institutions (MSIs), are encouraged. Applicants should consider how the developed programs can optimize participation and potentially include additional participants from outside the applicant institution, especially those in local and/or affiliated institutions. Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution. Each institution must have a unique program structure that maximizes resources, departments, and faculty at the applicant institution. Applicants are encouraged to propose collaborations with affiliated and/or local institutions, as appropriate. Applicants are also encouraged to partner with existing NIH-funded or other federally funded resources and programs and leverage training activities from both federal and private-sector partners including, but not limited to, the following: Alzheimer's Disease Research Centers (ARDCs) Centers on the Demography and Economics of Aging Claude D. Pepper Older Americans Independence Center (OAIC) Edward R. Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging Nathan Shock Centers Resource Centers for Minority Aging Research (RCMAR) NCATS Clinical and Translational Science Awards (CTSA) Research Centers in Minority Institutions Program (RCMI) Non-Responsiveness Criteria Applications that propose programs primarily outside of AD/ADRD research, or have a general STEM focus, will be considered non-responsive to this FOA and will be withdrawn prior to review. Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.

This funding opportunity supports innovative, interdisciplinary research projects that aim to fill critical knowledge gaps and advance scientific understanding in areas related to kidney, diabetes, and digestive diseases.

This grant provides funding to public health departments for collaborative research and initiatives aimed at improving food safety practices in retail food establishments and investigating foodborne outbreaks.

The specific purpose of this NOFO is to promote the development of a diverse, interdisciplinary workforce needed to conduct translational research on Alzheimer's disease and Alzheimer's-related dementias from target discovery through clinical development. This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). The program invites eligible institutions to develop interdisciplinary training programs that will provide trainees with the knowledge and skills in data science, disease biology, behavioral research, and traditional and emerging drug discovery disciplines necessary to conduct rigorous and cutting-edge basic, translational, and clinical research for AD/ADRD.

Grant Title: Pilot projects to enhance utility and usage of data sets from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) aims to fund small research projects that develop innovative methods to analyze and utilize MoTrPAC data, particularly focusing on how physical activity affects health, with a budget of up to $50,000 for one year.

The INFRA program, part of the MPDG, allocates $2.7 billion towards competitive grants for significant multimodal freight and highway projects that aim to improve the safety, efficiency, and reliability of freight and people movement across rural and urban areas. It focuses on projects that enhance economic benefits, reduce congestion, increase resiliency, and improve critical freight movements. The program encourages applications that address supply chain bottlenecks and are of national or regional significance. The application deadline is May 6, 2024.

This funding opportunity provides financial support to state and tribal agencies, community organizations, and collaborations focused on improving safety and well-being for families affected by domestic violence and child welfare issues.

This grant provides funding for research projects focused on improving health outcomes through lifestyle medicine for individuals affected by the 9/11 attacks, including responders and survivors receiving care under the WTC Health Program.

The "Blueprint Medtech: Small Business Translator" grant aims to support small businesses in developing and testing therapeutic and diagnostic devices for nervous or neuromuscular disorders, with funding and expert assistance provided for activities such as clinical studies, safety testing, and design validation, ultimately leading to FDA or IRB approval.

The REDI: NIA Entrepreneurship Enhancement Award (R25) is a grant aimed at providing entrepreneurial training to graduate students, postdocs, and early career scientists in fields related to aging and Alzheimer's disease research, to prepare them for diverse career paths.

This funding opportunity supports promising predoctoral students from diverse backgrounds to conduct research in translational studies related to Alzheimer's disease and related dementias, fostering skills essential for advancing this critical field.

Notice of Funding Opportunity Description Background Although vaccines are among the most effective approaches to control viral diseases, developing a prophylactic or therapeutic HIV vaccine has proven elusive. There are no licensed vaccines for HIV. Strategies for induction of HIV broadly neutralizing antibodies will likely require repeated exposures over long periods, including immunization with distinct antigens in sequential order. Such immunization strategies will require development of technologies for controlled vaccine release. Recent advances in materials-based science, controlled release technologies, delivery systems, and immunology provide opportunities to enhance the quality, potency and durability of vaccine-induced T cell and antibody responses to HIV-1. Materials-based approaches can be engineered to improve the stability, spatiotemporal release, and presentation of multiple vaccine components; for example, by controlling the time frame and dose of vaccine delivery over days to weeks. Recent studies have shown that a slow-release vaccine is superior to bolus administration at inducing breadth, potency, and durability of antibody responses to HIV antigens by prolonging antigen exposure in the germinal centers, thereby enhancing the maturation of B cells and generating stronger humoral immune responses. Further research is needed to elucidate the mechanisms underlying the immunological improvements observed with slow-release vaccine delivery and to translate such concepts into clinical application. It will be crucial to determine how the duration of exposure to vaccine components impacts immune cell biology, and how to calibrate vaccine release to improve responses while avoiding immune exhaustion and over-activation. Advancing safe, effective, and well-tolerated controlled release vaccines is an unmet need that may enhance vaccine effectiveness and practicality, leading to better adherence to complex regimens, fewer adverse reactions, and cost savings. Finally, iterative behavioral studies during product development to determine vaccine/provider product expectation/preferences are critical to facilitate product uptake and use.

This funding opportunity provides up to $100 million to various organizations for innovative projects aimed at developing vaccines, therapeutics, and research strategies to combat highly pathogenic avian influenza in the U.S. poultry industry.

This funding opportunity supports primary care centers in implementing genomic screening for common genetic conditions to improve disease prevention and care, particularly in underrepresented communities.

The U.S. Department of Justice (DOJ), Office of Justice Programs (OJP), Office for Victims of Crime (OVC) is seeking applications for funding. OJP is committed to advancing work that promotes civil rights and equity, increases access to justice, supports crime victims and individuals impacted by the justice system, strengthens community safety, protects the public from crime and evolving threats, and builds trust between law enforcement and the community. With this solicitation, OVC seeks to enable an organization to provide financial and technical assistance to approximately 300 communities (100 each year) nationwide to conduct public education and awareness activities on crime victims rights and services in their jurisdictions during the 20252027 National Crime Victims Rights Weeks (NCVRW). This program furthers the DOJs mission to uphold the rule of law, to keep our country safe, and to protect civil rights.

This funding opportunity provides financial support to state, local, and tribal governments, educational institutions, and nonprofits to improve recreational access and services on public lands in Alaska, particularly for underserved communities and in alignment with climate resilience and environmental stewardship goals.