Grants for Special district governments - Federal

This grant provides funding for researchers to explore how HIV and substance use disorders affect protein interactions in microglia, aiming to uncover mechanisms that could lead to new treatments for these interconnected conditions.

This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

This funding opportunity provides financial support to healthcare organizations and educational institutions for developing clinical decision support systems that integrate the latest research on Long COVID care, with a focus on improving patient outcomes and equity in underserved populations.

This funding opportunity is designed for researchers with existing NCI R01 grants to integrate innovative cancer research technologies into their projects, enhancing the study's impact and advancing the field of cancer research.

This funding opportunity supports innovative research projects aimed at understanding and improving the diagnosis, treatment, and services for individuals with Autism Spectrum Disorders, welcoming applications from a diverse range of organizations, including universities and nonprofits.

The purpose of this Notice of Funding Opportunity (NOFO) is to address the needs of the maternal and pediatric HIV scientific community for research data translation and sharing. This initiative will support secondary data analyses using archived HIV/AIDS data and specimens to generate new research questions and findings relevant to the scientific mission and priorities of the NICHD, Maternal and Pediatric Infectious Disease Branch (MPIDB) and Office of AIDS Research (OAR). The goal of this initiative is to encourage applicants to leverage existing datasets and employ new and advanced analysis techniques to answer scientific questions about the epidemiology, pathogenesis, treatment, clinical manifestations and complications of HIV/AIDS in maternal, pediatric and adolescent populations.

This funding opportunity is designed to support a network of organizations that will improve influenza modeling and forecasting to enhance public health responses and reduce illness in vulnerable populations.

Grant Title: Advanced Hydrogen and Fuel Cell Technologies to Drive National Goals aims to fund research and development of hydrogen and fuel cell technologies to help achieve a net-zero emissions economy by 2050, focusing on clean energy solutions for transportation, industrial processes, and energy storage.

The Pool Safely Grant Program funding opportunity assists states, local governments, and Native American Tribal Governments in implementing enforcement and education programs to prevent the drowning and drain entrapment of children in pools and spas.

This funding opportunity provides financial support for organizations to create and share resources that improve community policing practices and strengthen trust between law enforcement and the communities they serve.

This grant provides funding to state and local governments, tribal authorities, and other eligible entities for large bridge construction, rehabilitation, and replacement projects that improve safety and mobility across the United States.

This funding opportunity is designed to support organizations conducting rigorous evaluations of effective prevention strategies for intimate partner violence and sexual violence, particularly those that have been successfully implemented in communities for at least two years.

This funding opportunity supports the development of innovative informatics tools to improve cancer research and management, targeting researchers and institutions focused on enhancing data handling and analysis in the field of oncology.

This grant provides funding for early-career researchers from diverse backgrounds to receive mentorship and training in biomedical research focused on cardiovascular, pulmonary, and hematologic diseases, as well as sleep disorders, with an emphasis on addressing health disparities.

The grant titled "Investigating Distinct and Overlapping Mechanisms in TDP-43 Proteinopathies, including in LATE, FTD and other ADRDs" aims to fund research that deepens understanding of the mechanisms underlying TDP-43 proteinopathies, particularly their role in Alzheimer's Disease and related dementias, with the goal of improving diagnosis, treatment, and awareness of these conditions.

This funding opportunity provides financial support for state, local, and tribal governments, as well as nonprofits and educational institutions, to evaluate and improve crisis intervention programs aimed at enhancing public safety and addressing individuals in crisis.

This funding opportunity supports existing clinical research centers focused on liver cirrhosis to enhance patient recruitment, retention, and biospecimen collection while advancing research on disease outcomes and treatment strategies.

Scientific observations, experiments, and simulations are producing data at rates beyond our capacity to store, analyze, stream, and archive the data in raw form. Of necessity, many research groups have already begun reducing the size of their data sets via techniques such as compression, reduced order models, experiment-specific triggers, filtering, and feature extraction. Once reduced in size, transporting, storing, and analyzing the data is still a considerable challenge a reality that motivates SCs Integrated Research Infrastructure (IRI) program [1] and necessitates further innovation in data-reduction methods. These further efforts should continue to increase the level of mathematical rigor in scientific data reduction to ensure that scientifically-relevant constraints on quantities of interest are satisfied, that methods can be integrated into scientific workflows, and that methods are implemented in a manner that inspires trust that the desired information is preserved. Moreover, as the scientific community continues to drive innovation in artificial intelligence (AI), important opportunities to apply AI methods to the challenges of scientific data reduction and apply data-reduction techniques to enable scientific AI, continue to present themselves [2-4].The drivers for data reduction techniques constitute a broad and diverse set of scientific disciplines that cover every aspect of the DOE scientific mission. An incomplete list includes light sources, accelerators, radio astronomy, cosmology, fusion, climate, materials, combustion, the power grid, and genomics, all of which have either observatories, experimental facilities, or simulation needs that produce unwieldy amounts of raw data. ASCR is interested in algorithms, techniques, and workflows that can reduce the volume of such data, and that have the potential to be broadly applied to more than one application. Applicants who submit a pre-application that focuses on a single science application may be discouraged from submitting a full proposal.Accordingly, a virtual DOE workshop entitled Data Reduction for Science was held in January of 2021, resulting in a brochure [5] detailing four priority research directions (PRDs) identified during the workshop. These PRDs are (1) effective algorithms and tools that can be trusted by scientists for accuracy and efficiency, (2) progressive reduction algorithms that enable data to be prioritized for efficient streaming, (3) algorithms which can preserve information in features and quantities of interest with quantified uncertainty, and (4) mapping techniques to new architectures and use cases. For additional background, see [6-9].The principal focus of this FOA is to support applied mathematics and computer science approaches that address one or more of the identified PRDs. Research proposed may involve methods primarily applicable to high-performance computing, to scientific edge computing, or anywhere scientific data must be collected or processed. Significant innovations will be required in the development of effective paradigms and approaches for realizing the full potential of data reduction for science. Proposed research should not focus only on particular data sets from specific applications, but rather on creating the body of knowledge and understanding that will inform future scientific advances. Consequently, the funding from this FOA is not intended to incrementally extend current research in the area of the proposed project. Rather, the proposed projects must reflect viable strategies toward the potential solution of challenging problems in data reduction for science. It is expected that the proposed projects will significantly benefit from the exploration of innovative ideas or from the development of unconventional approaches. Proposed approaches may include innovative research with one or more key characteristics, such as compression, reduced order models, experiment-specific triggers, filtering, and feature extraction, and may focus on cross-cutting concepts such as artificial intelligence or trust. Preference may be given to pre-applications that include reduction estimates for at least two science applications.

This grant provides funding to local governments and nonprofits for technologies and programs that help locate individuals with dementia or developmental disabilities who are at risk of wandering, enhancing public safety and community support.

This funding opportunity supports innovative research projects focused on understanding and advancing treatments for nonmalignant blood disorders, encouraging collaboration and involvement from new researchers in the field.