Federal Health Grants

The NIH Directors Pioneer Award Program supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Directors Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

This grant provides funding to higher education institutions and nonprofit organizations to train future professionals in vocational rehabilitation services for individuals with disabilities, addressing personnel shortages in the field.

This funding opportunity provides financial support to healthcare systems for implementing comprehensive suicide prevention strategies, particularly targeting vulnerable populations such as older adults, Native Americans, and veterans.

This funding opportunity provides financial support to organizations implementing strategies to prevent diabetes and improve health equity for populations at risk, focusing on statewide, local, or multisectoral approaches.

This funding opportunity supports research centers focused on understanding how biological sex differences affect women's health, promoting interdisciplinary collaboration and workforce diversity in the scientific community.

This funding opportunity supports the establishment of a center that fosters collaboration between researchers in substance use epidemiology and prevention to develop effective strategies for preventing substance use and related issues.

This funding opportunity provides financial support to state and tribal governments to improve prescription drug monitoring systems, enhance data sharing, and combat the misuse of controlled substances, particularly opioids.

trainer program to educate, train, and prepare jail and prison staff so they are equipped to appropriately interact with people in a carceral setting who have mental illness (MI) and intellectual and developmental disabilities (IDD). This training should be developed by an institution of higher education or non-profit, for profit or tribal in conjunction with health care and corrections professionals to ensure a multidisciplinary approach. The training must focus on understanding behavioral health, including MI and substance use disorders, IDD, developing empathy, navigating community resources, and de-escalation skills and practical application training of those skills in a trauma-informed manner for all staff working in prisons and jails. The centerpiece of this training must be a 40-hour CIT train-the-trainer program.

This funding opportunity provides financial support to U.S. state and territorial governments for implementing and improving residential substance use disorder treatment programs in correctional facilities, with a focus on reducing recidivism and ensuring continuity of care after release.

Synopsis: NOFO # DD24-0051 solicits non-research, cooperative agreement applications to conduct population-based surveillance of congenital heart defects (CHD) to describe health outcomes including health equity, with the goal of identifying opportunities to improve the health of all people living with CHD. This project will involve a required component (A) and an optional component (B). The population included in this surveillance activity can be an entire state or a region within a state. Individuals with CHD should be identified through existing data sources including the jurisdiction birth defects surveillance system, electronic health records, administrative data (e.g., Medicaid/Medicare, hospital discharge), or other sources available to funding recipients. Background: Congenital heart defects (CHD) affect about 1% of all births in the United States, and are a leading cause of birth defect-associated infant mortality, morbidity, and healthcare costs. Improvements in early detection and treatment of CHD and consequently in survival have resulted in many people, including those affected by a severe CHD, living into adolescence and adulthood. An estimated two million persons in the U.S. are living with a CHD, including over one million adults; about 12% of these affected adults have a severe CHD. Most current efforts to conduct population-based surveillance of CHD have focused on monitoring newborns. However, little data exist on the descriptive epidemiology of CHD beyond early childhood in the U.S. Despite the public health burden, the lack of population-based surveillance precludes reliable data on people with CHD, their survival, healthcare utilization, and characteristics associated with long-term outcomes. Through this surveillance activity, these data will be assessed, enabling and informing efforts to improve the health and well-being of people with CHD. Objectives: Component A objectives include: (1) assess survival, comorbidities, healthcare utilization during the period 2021-2023, and characteristics associated with long-term outcomes among people with CHD; (2) assess health equity among people with CHD; (3) examine state and national healthcare policies that have an impact on people with CHD; (4) examine COVID-19 and related data such as health care utilization during the pandemic among people with CHD; and (5) work with local/state partners to use site-specific CHD data. Component B objectives include: (1) develop and refine a machine learning algorithm for the surveillance data collected through Component A; and (2) apply this machine learning algorithm to data collected from all recipients funded through Component A.

This funding opportunity supports experienced researchers looking to expand their expertise or shift their career focus through advanced training and research experiences at various institutions.

The National Institutes of Health (NIH) Institutes and Centers (ICs) intend to reissue a Notice of Funding Opportunity (NOFO) to continue the Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) program. The full list of participating ICs will be available in the published NOFO. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications. The NOFO is anticipated to be published in Spring 2024 with an expected first application due date in Summer 2024. The NOFO will utilize the R15 activity code. Pertinent details of the planned NOFO are provided below.

This funding opportunity provides financial support to federally recognized Indian Tribes and Alaska Native organizations to enhance victim services and address the needs of families affected by missing or murdered Indigenous persons in their communities.

This grant provides funding to Indian Tribes and authorized tribal organizations to develop tailored AmeriCorps programs that address community needs and enhance local capacity for future service initiatives.

This funding opportunity provides financial support to small businesses collaborating with academic or non-profit labs to develop and commercialize innovative technologies and treatments for arthritis, musculoskeletal, and skin diseases.

This funding opportunity supports innovative research into the biological mechanisms behind complex brain disorders, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

This funding opportunity supports a wide range of organizations in developing innovative drug therapies for Alzheimer's disease and related dementias, focusing on non-traditional treatment targets and requiring collaboration with NIH throughout the clinical trial process.

This funding opportunity supports innovative research into new risk factors for liver cancer, particularly focusing on non-viral causes and their interactions with established risks, aimed at improving prevention strategies in the U.S. population.

This funding opportunity provides financial support for researchers and organizations to investigate the factors driving tuberculosis transmission and develop innovative methods for prevention and detection in high-burden areas.

This grant provides funding to organizations in Maine, New Hampshire, New York, and Vermont to train and place behavioral health professionals in rural areas facing a shortage of providers.