Federal Health Grants

This funding opportunity supports U.S.-based small businesses in the clinical validation of biomarkers for neurological or neuromuscular disorders, promoting inclusivity and collaboration while ensuring rigorous scientific standards for potential diagnostic and therapeutic applications.

Reissue of PAR-20-118. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This FOA using the U01 mechanism supports a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies Projects seeking support for a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach should consider the companion U19 FOA.

This grant provides funding for research studies that explore the relationship between autophagy, HIV infection, and substance use disorders, aiming to uncover mechanisms that could lead to new therapeutic strategies for affected individuals.

This grant seeks to improve health and support services for children, adolescents, youth, and families affected by the HIV epidemic in Eswatini, focusing on prevention, resilience, and sustainable interventions.

This grant provides $7.5 million to local organizations in Madagascar to strengthen public health surveillance, research, and data use, particularly in response to health security threats and outbreaks.

This grant provides funding to coalitions of local governments and nonprofit organizations to assess and plan for the redevelopment of contaminated properties, helping communities revitalize brownfield sites safely.

This funding opportunity provides resources to support global health initiatives aimed at preventing, detecting, and responding to public health threats in collaboration with health ministries and governmental institutions worldwide.

This funding opportunity provides financial support for research projects that evaluate effective strategies to prevent child sexual abuse and problematic sexual behavior among youth, particularly through community partnerships and addressing health equity.

This funding opportunity supports educational programs that provide research experiences for undergraduate students from diverse backgrounds to encourage their pursuit of careers in aging-related research.

The National Cancer Institute (NCI) intends to issue a notice of funding opportunity (NOFO) for the Research Specialist Award (R50) specifically for clinician scientists supporting NCI-funded clinical trials research. The Research Specialists Award is designed to encourage the development of stable research career opportunities for exceptional clinician scientists who want to continue to participate in the NCI clinical trials networks through leadership in the 1) development of clinical trials, 2) implementation of NCI clinical trials in their institutions, and 3) national service to the NCI clinical trials networks through participation in the scientific review committees, monitoring committees and other activities, but not serve as principal investigator of research project grants. This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications. Applications are limited to four per institution per receipt date including new (A0) and resubmissions (A1). NCI-designated cancer center consortia are considered one institution. NCI seeks a broad representation of institutions for this award mechanism and may take this into account when making funding decisions. The NOFO is expected to be published in late summer 2024 with only one expected application due date of November 5, 2024.

This grant provides funding for research projects that explore how climate change affects cancer risks and care, particularly focusing on vulnerable populations and aiming to reduce health disparities.

This funding opportunity provides financial support to public and nonprofit organizations to deliver comprehensive primary health care services in underserved communities across the United States.

The activity seeks to achieve improved TB and HIV/AIDS client outcomes through supporting community-led monitoring activities that will lead to improvements in health service quality. This activity will bolster community leadership, support robust community health sector engagement and increase community participation inhealth system decision-making. Specifically, the activity will: (1) enhance the functionality and coordination of networks of community-led and community-based organizations engaged in the TB and HIV response; (2) strengthen existing platforms to collect and analyze data to inform TB and HIV programming; and (3) bolster the capacity of community-based organizations to carry out data-driven advocacy at the national and local levels.

The U.S. Department of State, U.S. Embassy in Kinshasa - Democratic Republic of Congo through the U.S. Presidents Emergency Plan for AIDS Relief (PEPFAR) Coordination Office (PCO) is pleased to announce an open Notification of Funding Opportunity (NOFO) for organizations to submit applications that support Community - led Monitoring (CLM) activities, to be implemented in close collaboration with local Community-based organizations and other civil society groups, networks of key populations (KP), people living with HIV (PLHIV), youth and adolescents including children and other HIV-affected groups. The CLM program will be implemented in the three PEPFAR provinces including Kinshasa, Haut-Katanga and Lualaba. Community-led monitoring or CLM is a routinized process initiated and implemented by local HIV-positive and HIV-affected communities, community-based organizations and other civil society groups that identifies HIV service delivery successes, diagnoses problems, uses quantitative and qualitative data to overcome barriers and ensure that HIV service beneficiaries receive optimal client-centered services. The intention of CLM is for local community leadership to get inputs from recipients and providers of HIV services, including key populations and underserved groups, in a routine and systematic manner and translate their findings into action and change in collaboration with host governments and health systems. CLM is a tool within the community engagement process, a strategic collaboration of multiple partnerships within a designated geographic location. CLM leverages community engagement to empower community members to identify successes, diagnose problems, use data-driven approaches to overcome barriers, and ensure beneficiaries receive optimal client-centered services in a productive, collaborative, respectful, and solutions-oriented manner. This community-driven approach to addressing health challenges often evolves into advocacy, whether driven by the individual, community, organizations, or institutions. The CLM program is funded through the U.S. Presidents Emergency Plan for AIDS Relief (PEPFAR). The goal of PEPFAR in DRC is to support efforts to achieve HIV epidemic control through implementation of evidence-based interventions to drive progress in HIV prevention, care and treatment and ultimately, save lives. Through the PEPFAR Coordination Office, the U.S. Embassy in Kinshasa administers this Community grants program and is seeking proposals from registered local Community-based organizations and other civil society groups, networks of key populations (KP), people living with HIV (PLHIV), youth and adolescents including children and other HIV-affected groups, or community entities that gather quantitative and qualitative data about HIV services and whose mission and activities focuses on HIV programming. CLM plays key role to ensuring availability, accessibility, affordability, acceptability, and delivery of timely and quality HIV care and services. CLM will raise public awareness on the rights of PLHIV, KP groups, youth and adolescents and other affected communities, will empower beneficiaries and affected communities to speak out, to increase health literacy, to expand engagement with health service providers, to support demand creation, on one hand; and on the other hand, CLM will hold decisions makers accountable for executing changes to improve HIV service delivery. CLM data will be collected using standardized tools and synthesized through a variety of methods that reveal insights from communities about problems and solutions to health and HIV service delivery at: the facility, community, sub-national and national levels. Thus, CLM data builds evidence on what works well, what is not working and what needs to be improved, with suggestions for targeted action to improve outcomes. Monitoring data should reflect an added value and not duplicate collection of routine data already available to PEPFAR, through its standard reporting. Added value monitoring data includes, but not limited to information from beneficiaries about their experience with the health facility, information about barriers and enablers to access and retention in services etc. CLM mechanisms must be routine to ensure follow up and continuous improvement for sustainability. Results from CLM will be shared with all the stakeholders including host governments, health systems, PEPFAR implementing partners and the PEPFAR team on a regular and systematic basis (monthly, quarterly, and annually), for informing decisions, to improve time and quality service delivery.

ATTENTION: All Interested PartiesThe United States Government, represented by the U.S. Agency for International Development (USAID)/Afghanistan, is seeking input from interested organizations and individuals who may provide information, opinions, and recommendations in response to the questions outlined in this RFI for potential USAID interventions to increase equitable access to and utilization of quality health and nutrition services and adoption of healthy behaviors, especially for women and children in targeted areas. This is not a solicitation. This Request for Information (RFI) notice is solely issued for information and planning purposes only. Responses to this notice are not considered an application and will not be accepted or evaluated by the Government as a result of this RFI. Only responses with the information requested in this RFI will be reviewed. Responses received may be used for planning and design purposes. USAID is exploring the design of a new health activity to increase equitable access to and utilization of quality health and nutrition services and adoption of healthy behaviors, especially for women and children. This RFI solicits information, opinions and recommendations from interested organizations and individuals related to the questions below.Please refer to the attached RFI document for more details.

This Annual Program Statement (APS) offers USAID Operating Units a mechanism to facilitate assistance awards to local and non-traditional partners for innovative, adaptive, and locally led development approaches. OUs may issue addenda under this umbrella to solicit, co-create, and fund a wide range of flexible and innovative approaches to locally led development related to their specific priorities, objectives, and programs. The APS aims to advance USAIDs capability to work with local partners, to learn from these engagements, and to share this learning broadly. INTERESTED APPLICANTS - PLEASE READ: This Locally Led Development APS is not a Request for Applications or a Request for Proposals, and this APS does not serve as a general request for locally led development concepts. Do not email concepts to LLD-APS@usaid.gov or submit concepts via grants.gov, as they will not be accepted. Interested Applicants must respond to specific documents that share USAID priorities in a specific country(ies) called addenda that may be issued throughout the year on grants.gov. These addenda, when added, can be found under Related Documents on this page. Please visit this page periodically for opportunities that may be relevant to your country and focus areas. Please see the attachment for further detailed information. This APS was last updated April 26, 2024, with Amendment 1 - 7200AA19APS00007 Locally Led Development Annual Program Statement (APS) 2024-4-26

This funding opportunity supports research that investigates how sex and gender differences impact health outcomes and disease management, targeting a wide range of eligible organizations, including universities and nonprofits.

This funding opportunity supports a variety of organizations in developing and testing new clinical applications derived from basic research to improve health outcomes for individuals with communication disorders.

The purpose of the Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01) is to provide support and protected time (three, four, or five years) for an intensive, supervised career development experience in biomedical, behavioral, and social science research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing and that will lead to research independence. Research projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) as mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31.

The National Institute on Alcohol Abuse and Alcoholism ( NIAAA) intends to reissue RFA-AA-23-001, Specialized Alcohol Research Centers (P50, Clinical Trial Optional), by publishing a NOFO to solicit applications for a broad-based Alcohol Research Centers program to foster and conduct interdisciplinary, collaborative research on Alcohol Use Disorder (AUD), alcohol misuse and alcohol-related problems, and other health-related consequences across the lifespan. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Spring 2024 with an expected application due date in Fall 2024. This NOFO will utilize the P50 activity code. Details of the planned NOFO are provided below.