Federal Health Grants

This funding opportunity supports small research teams in developing innovative biomedical technologies that address critical health challenges and improve healthcare accessibility.

This program will support projects to identify and characterize factors associated with gender-affirming hormone therapy (GAHT) that may impact/contribute significantly to the prevention and treatment of HIV and/or co-infections with other sexually transmitted infections (STI)s in transgender individuals. For this funding opportunity GAHT is defined as a medical intervention, including but not limited to estrogen and/or testosterone treatment, that results in acquisition of secondary sex characteristics that align with an individual's gender identity. A growing body of data indicates that GAHT may impact the effectiveness and implementation of biomedical HIV prevention or treatment strategies and/or co-infections with other STIs. A number of factors in transgender populations present research challenges including variability in GAHT regimens, use of auxiliary drugs during GAHT care, access to participants, and access to existing cohorts, datasets, and samples. Consideration of appropriate controls, including cis-gender men and women is also a barrier. Recent studies demonstrating recruitment and retention of participants undergoing GAHT provide the opportunity to build on those studies and provide confidence that these critical studies are feasible.Letter of Intent Due Date(s) 30 days prior to the application due date

The Preventive Health and Health Services (PHHS) Block Grant Program allows recipients to address their own unique public health needs and challenges with innovative and community-driven methods. Recipients set their own goals and program objectives and implement local strategies to address Healthy People 2030 priorities.

This funding opportunity supports research centers focused on improving maternal and child health outcomes through innovative studies and partnerships, particularly addressing disparities and critical health challenges.

This grant provides funding to nonprofit organizations serving culturally specific communities to enhance and expand support services for victims of sexual assault.

This funding opportunity supports innovative research projects aimed at improving understanding and treatment of tuberous sclerosis complex, targeting areas such as neuropsychiatric disorders, tumor management, and patient care advancements.

This funding opportunity supports postdoctoral researchers in the National Institute of Mental Health's intramural program as they transition to independent academic careers in mental health research.

The NINDSintends to reissuePAR-23-027 to solicit applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pesticides that have primary or secondary effects on the nervous system. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. Projects supported by this NOFO are expected to generate data that elucidate mechanisms of toxicity of these agents, possible new manifestations of toxic exposures, and potential new targets for therapeutic development. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Winter 2024 with an expected application due date in Spring 2024. This NOFO will utilize the R01 activity code. Details of the planned NOFO are provided below.

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma. The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying those patients at high risk of PDAC (because of genetic factors or presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; determine which pancreatic cysts are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens and data within the Consortium. The other scientific component of the PCDC will be the Management and Data Coordination Unit (MDCU). The PCDC-MDCU will provide support toward study design, protocol development, statistical analysis, coordination, harmonization, data management and stewardship for the trans-PCDC collaborative projects, including biorepository building effort.

This funding opportunity supports researchers and organizations in validating biomarkers for neurological and neuromuscular disorders to improve clinical trials and patient care.

This funding opportunity supports U.S. higher education institutions with doctoral programs in health professions to enhance their research capabilities and address health disparities through collaborative research projects.

This funding opportunity provides financial support to small U.S.-based businesses for the development and validation of analytical methods to measure biomarkers related to neurological and neuromuscular disorders, with an emphasis on enhancing inclusivity and collaboration in research.

This funding opportunity supports innovative research to improve personalized probiotic treatments by studying individual biological factors that influence how people respond to probiotics.

This funding opportunity supports the establishment of a 24-hour hotline to provide crisis intervention and resources for Indigenous victims and survivors of family violence, ensuring they receive culturally relevant and accessible services.

This grant provides funding for innovative research projects that explore the effects of HIV/AIDS on communication disorders and develop strategies to improve the quality of life for individuals living with HIV.

This funding opportunity provides financial and technical support to federally recognized Indian Tribes and Tribal Organizations to strengthen their health management capabilities and improve service delivery under the Indian Self-Determination and Education Assistance Act.

The purpose of this Notice is to alert the community that the National Institute of Neurological Disorders and Stroke (NINDS) plans to reissue initiativeRFA-NS-21-033 Materials to Enhance Training in Experimental Rigor (METER) with one receipt date. The program is designed to support the compilation and refinement of educational materials that will be incorporated into a new cutting-edge online resource that aims to promote awareness, understanding, and practice of fundamental principles of rigorous biomedical research for scientists in various career stages and learning environments. Awardees will collaborate with the established coordinating center, which is funded by the companionRFA-NS-21-009 Creating an Educational Nexus for Training in Experimental Rigor (CENTER). This coordinating center (CENTER) is responsible for organizing the initiative, building the final web-based platform, harmonizing the educational units, and producing digital elements (e.g., videos, graphics, interactive components) that are beyond the technical capabilities of METER awardees. This collaboration between CENTER and METER awardees will include activities to improve, finalize, evaluate, and disseminate the resulting educational units drafted by METER awardees. More information about the initiative, its current progress, and frequently asked questions can be found at https://www.ninds.nih.gov/current-research/trans-agency-activities/rigor-transparency/initiative-improve-education-principles-rigorous-research. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The overall objectives of the program have not changed; however, potential applicants can expect minor changes to improve the clarity of the previous announcement. The NOFO is expected to be published in Summer 2024 with an expected application due date in October 2024. This NOFO will utilize the UE5 activity code. Details of the planned NOFO are provided below.

This funding opportunity provides financial support to U.S.-based organizations for the late-stage development and dissemination of biomedical technologies that have shown laboratory feasibility, aiming to enhance their accessibility and usability in the research community.

This funding opportunity supports researchers in developing new medications to prevent and treat opioid and stimulant use disorders and overdose, with a focus on advancing promising treatments towards FDA approval.

This funding opportunity provides financial support to nonprofit organizations and government entities to improve access to meal programs for older adults with behavioral health conditions, including those experiencing homelessness, across the state.