Federal Science and Technology Grants

This funding opportunity provides financial support for U.S.-based researchers and organizations to develop and implement innovative technologies and strategies that prevent, control, or mitigate the impacts of harmful algal blooms on public health and coastal economies.

This funding opportunity supports innovative research on rare cancers, providing up to $490,000 for early-stage projects that aim to improve diagnosis, understanding, and treatment, particularly benefiting military service members, veterans, and the general public.

This funding opportunity provides financial support for innovative projects that develop practical solutions to improve the lives of individuals with disabilities, particularly those with the greatest support needs.

This funding opportunity provides financial support to nonprofit organizations and higher education institutions for initiatives that improve earthquake safety and awareness across multiple states or nationally.

This is a Request for Information (RFI) only. This RFI is not accepting applications for financial assistance. The purpose of this RFI is solely to solicit input for ARPA-E consideration to inform the possible formulation of future programs. The purpose of this Request for Information (RFI) is to solicit input for a potential ARPA-E program focused on the development of technologies to recover high energy-value materials from wastewater to reduce energy demands and greenhouse gas (GHG) emissions associated with conventional sourcing and waste stream treatment. Wastewater in this RFI is broadly defined, and includes municipal, livestock, industrial, and mining sources. High energy-value materials under consideration are nutrients (i.e., ammonia and phosphorus) and critical minerals, where the latter are a group of 50 elements in the periodic table including lithium and rare earth elements (REEs). To view the RFI in its entirety, please visit https://arpa-e-foa.energy.gov.

This funding opportunity is designed to support partnerships among industry, government, and academia in developing and testing innovative mining technologies to strengthen the U.S. supply chain for critical minerals essential for energy and national security.

This grant provides funding to non-profit organizations in the U.S. and Ukraine to establish and strengthen partnerships between cities, promoting economic development, innovation, and cultural exchange in support of Ukraine's recovery and democratic growth.

This funding opportunity is designed for U.S.-based research institutions to advance the measurement of exoplanet masses, enhancing our understanding of their characteristics and formation processes.

The OCRP seeks to advance ovarian cancer research through development of early-career investigators. The OCRP Ovarian Cancer Academy (OCA) is a unique, interactive environment providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty to move ovarian cancer research into a new frontier. The overarching goal of the OCA is to develop successful, highly productive ovarian cancer researchers in a collaborative research and career development environment to enhance quality and expand quantity of the ovarian cancer research field.

This grant provides funding to U.S.-based organizations, including universities and companies, to develop innovative technologies that enhance plant engineering for sustainable energy and bioenergy production.

This funding opportunity provides financial support to research institutions and organizations to establish centers that advance tuberculosis research through collaboration, shared resources, and the development of new scientific leaders.

The FY24 KCRP Concept Award supports highly innovative, untested, potentially groundbreaking novel concepts in kidney cancer. The Concept Award is not intended to support an incremental progression of an already established research project but, instead, it allows Principal Investigators (PIs) the opportunity to pursue serendipitous observations. Preliminary data are not allowed and should not be discussed. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for investigation. Applications must describe how the new idea will enhance the existing knowledge of kidney cancer or develop an innovative and novel course of investigation. Research completed through a Concept Award may generate sufficient preliminary data to enable the PI to prepare an application for future research.Organizational-Level Emphasis Areas:The following areas of emphasis are broadly applicable to many CDMRP programs, not just the KCRP. Investigators are encouraged to consider addressing these areas in their applications if doing so is appropriate for their line of research, addresses the FY24 KCRP strategic priorities and/or focus areas described in Section II.A.1 and Section II.A.2.Nuclear Medicine: Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Womens Health: CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in womens health outcomes and/or advancing knowledge for womens health.Metastatic Cancer Task Force: A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 KCRP priorities.Rigorous Study Design: All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Military Service Involvement: Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborator(s), and their organization(s). Refer to Section II.D.2.b.i, Full Application Guidelines, for more information.Clinical trials are not allowed under this funding opportunity.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 KCRP Concept Award should not exceed $100,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $1.44M to fund approximately nine Concept Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity supports U.S. institutions conducting theoretical astrophysics research to improve our understanding of cosmic phenomena through innovative modeling and data interpretation.

This grant provides funding for interdisciplinary teams of graduate students, researchers, and industry professionals to explore and propose solutions for integrating renewable energy into the U.S. electric grid.

This funding opportunity supports collaborative research and mentorship projects in science, particularly aimed at enhancing participation and career development for underrepresented groups in STEM fields across diverse academic institutions.

This funding opportunity provides financial support for local non-government organizations in Algeria to implement projects that foster cultural, educational, and scientific exchanges between the United States and Algeria.

This grant provides funding for researchers focused on understanding solar activity and its effects on the Earth's environment, aiming to improve predictions of space weather events.

This grant provides funding for research in physical sciences, targeting a wide range of organizations, including government and private entities, to advance knowledge and technology in space and Earth sciences.

Collaboration Opportunity Announcement (COA) for Parties Interested in Partnering with the National Energy Technology Laboratory (NETL) under FOA 24-3210 Competitive Portfolios for Advanced Scientific Computing Research This is only an opportunity notice. Any information contained in this opportunity notice is subject to change. DOE will not respond to individual submissions or publish a compendium of the responses made to this opportunity notice. A submittal in response to this opportunity notice shall not constitute or create a binding commitment to develop or pursue the project or ideas discussed within a particular submittal. DOE is under no obligation to partner or collaborate with any entity who submits a response to this opportunity notice. DOE may choose to partner or collaborate with one or more or none of the responding entities. The terms and conditions of any resulting partnership or collaboration shall be memorialized in a future written agreement. The costs incurred to submit a response to this opportunity notice will not be borne by the Government.

This funding opportunity provides financial support for researchers to explore the molecular mechanisms that enhance the productivity and resilience of bioenergy crops, while also investigating the role of microbial communities in promoting plant health and sustainability.