Federal Science and Technology Grants

The "DoD Rare Cancers, Idea Development Award" is a grant aimed at supporting early-stage research ideas with high potential impact, which could lead to significant advancements in the diagnosis, treatment, and improved health outcomes for individuals suffering from rare cancers, with a particular focus on innovative research involving nuclear medicine, women's health, and adherence to rigorous study design standards.

The NNSA Academic Programs and Community Support, Office of Advanced Simulation and Computing (ASC) and Institutional Research and Development Programs (NA-114), Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL) and Sandia National Laboratories (SNL), are initiating the next phase of its academic program, called Predictive Science Academic Alliance Program IV (PSAAP IV). PSAAP IV will add an additional focus, on the development and application of artificial intelligence (AI) and machine learning (ML) technologies to improve quantified predictive capabilities. The DOE NNSA Academic Programs and Community Support PSAAP IV Notice of Funding Opportunity (NOFO), DE-FOA-NA0003284, and succeeding awarded agreements, are made possible from NNSAs statutory authority, and are managed by applicable guidance, regulations, and laws. Predictive Science Academic Alliance Program IV (PSAAP IV) will support leading U.S. institutions of higher education, with doctoral programs, engaging in five major focus areas: 1. Discipline-focused research to further predictive science and enabled by effective exascale computing and data science technologies; 2. Mathematics and computer science (CS) technologies and methodologies to support effective exascale computing in the context of science/engineering applications (development and demonstration); 3. State-of-the-art machine learning (ML) and data science technologies for predictive science and engineering (utilization and advancement); 4. Predictive science based on verification, validation, and uncertainty quantification (VVUQ) for large-scale simulations; and 5. Workforce development of the next-generation computational scientists. PSAAP IV will create a program consisting of two types of Centers: Predictive Simulation Centers (PSCs) and Focused Investigatory Centers (FICs). 1. Predictive Simulation Centers (PSCs) will be required to focus their research on scalable application simulations, targeting either large-scale, integrated multidisciplinary problems or a broad single science/engineering discipline, to be carried out on ASCs unclassified high-performance computing (HPC) systems that will be made available to the funded PSAAP IV Centers. A PSC must (1) develop and demonstrate computer and/or data science technologies and methodologies that will advance exascale computing, and (2) demonstrate a verified and validated predictive simulation (or simulation-driven workflow) with uncertainty quantification. Both (1) and (2) must be demonstrated within the context of the proposed application. It is expected that a PSC will demonstrate a compelling and significant advance in predictive science, in the context of their application. The overall goal should require the integration of state-of-the-art techniques and advances in physical science, scientific machine learning, and exascale-enabled computer/computational science to demonstrate improved predictive capability. This should be manifested as predictions of a wider range of phenomena, with improved predictive accuracy and reduced uncertainty, in comparison to existing capabilities at the beginning of the project. Integrated system simulation (or simulation-driven workflow) results for a single demonstration problem must be produced each year, beginning in the second year of the program. All research efforts within a PSC must contribute towards advancing this predictive capability and be integrated no later than the year 4 demonstration. It is anticipated that PSCs will be 5-year awards at $1.5-3.5M per year, with the larger-award sizes for Centers targeting multidisciplinary problems and advancing both CS and ML technologies. 2. Focused Investigatory Centers (FICs) will be required to be tightly focused on a specific research topic either in one of the disciplines or one or more of the exascale-enabling CS, ML, or VVUQ technologies listed below. FICs will not necessarily have a tie to an application or be required to demonstrate a verified, validated predictive simulation with uncertainty quantification. Successful FIC will demonstrate a compelling and significant scientific advance in the single discipline or enabling technology. The technical advance should represent a qualitative step up in the discipline, as opposed to incremental progress. It is anticipated that FIC awards will be up to 5-year awards, at $0.5-1.0M per year. DOE/NNSA will award cooperative agreements under this NOFO. DOE/NNSA will consider funding multi-institution teams submitted as a prime and subaward model with one application submitted by the lead institution (prime applicant). Approximately $20,000,000 annually is anticipated to be available for awards under this NOFO. Funding for all awards and future budget periods are contingent upon the availability of funds appropriated by Congress for the purpose of this program and the availability of future-year budget authority. Grants.gov Questions Direct questions relating to the Grants.gov registration process, system requirements, application form, or the submittal process must be directed to Grants.gov at 1-800-518-4726 or support@Grants.gov. DOE/NNSA staff are unable to answer Grants.gov questions. NOFO Questions Direct specific program and technical questions through FedConnect found at FedConnect - Gateway to Government Opportunities. Responses to FAQs will be posted periodically via FedConnect to registered applicants. Responses to FAQs will also be posted to the PSAAP IV FAQs website at PSAAP-IV NOFO FAQ PSAAP (llnl.gov)

This funding opportunity supports innovative research aimed at preventing Alzheimer’s disease and related dementias, particularly in relation to military service and traumatic brain injury, targeting independent researchers from various eligible organizations.

The U.S. Department of Justice (DOJ), Office of Justice Programs (OJP), National Institute of Justice (NIJ) is seeking applications for funding. OJP is committed to advancing work that promotes civil rights and equity, increases access to justice, supports crime victims and individuals impacted by the justice system, strengthens community safety and protects the public from crime and evolving threats, and builds trust between law enforcement and the community. With this solicitation, NIJ seeks proposals for rigorous applied research and evaluative studies on innovations, initiatives, and strategies in both institutional and community corrections. This program furthers DOJs mission to uphold the rule of law, to keep our country safe, and to protect civil rights.

With this solicitation, NIJ seeks to continue funding to support the Law Enforcement Advancing Data and Science (LEADS) Scholars Program, an ongoing NIJ program designed to increase the in-house research capabilities of law enforcement agencies by building data and research skills of individuals employed by and engaged with these agencies.

This initiative seeks input from various stakeholders, including businesses, researchers, and government entities, to enhance the recycling and reuse of products and materials, ultimately promoting environmental sustainability and economic resilience.

This funding opportunity supports U.S. and Canadian organizations in creating public diplomacy projects that foster mutual understanding and cooperation between the two countries, focusing on shared interests like innovation, security, and cultural exchange.

The U.S. National Science Foundations Directorate for Technology, Innovation and Partnerships (TIP) is charged with accelerating use-inspiredand translationalresearch and development (R) to advance U.S. competitiveness in key technology focus areas. The Advancing Cell-Free Systems Toward Increased Range of Use-Inspired Applications (CFIRE) initiative will accelerate the adoption of cell-free systems, enable new applications of this technology and contribute to the growth of the U.S. bioeconomy. A nascent industry has formed around the ability to carry out biochemical processes, such as DNA transcription/translation, in cell-free in-vitro systems instead of in traditional cell-based in-vivo bio-reactors. This approach has a number of potential advantages, including rapid turn-around, distributed and highly retargetable manufacturing, high-fidelity instrumentation and control of the manufacturing environments without the constraints of biological growth and the interference caused by cell biomass and cell membranes during product purification. Furthermore, cell-free systems can produce products that are challenging to manufacture in cell-based cultures, such as those inherently toxic to cells or hydrocarbon products that are consumed by the cellular machinery. Despite these advantages, present-day cell-free manufacturing is significantly more expensive than cell-based methods and cell-free systems have a limited range of applications. CFIRE aims to: 1. Reduce the cost of cell-free systems; 2. Increase the range and capabilities of cell-free systems; and 3. Develop and demonstrate cost-effective use-inspired applications. CFIRE will address the key limitations of cell-free technology by identifying technical approaches that can enable ongoing cycles of improvement. The objective is to place cell-free technology on an exponential growth path in which reduced costs lead to increasing adoption which, in turn, generates the learning and investment required to further reduce costs. In order to keep the work focused and to stimulate increasing adoption, efforts funded through this initiative will focus on one or more specific use cases. CFIRE seeks significant breakthroughs that will accelerate the adoption of cell-free systems by: (a) Demonstrating the feasibility and advantages of cell-free systems through use-inspired applications with specific emphasis on applications beyond human therapeutics; (b) Creating infrastructure components, such as tools, protocols, kits, datasets, and characterization services that can readily be accessed by third parties; and (c) Investing in workforce components focused on the training of translational talent with the skills and passion to engage in use-driven cell-free applications. CFIRE will use the Ideas Lab process (see PAPPG Chapter II.F.6), starting with an intensive meeting that brings together multiple diverse perspectives. The primary objectives of this Ideas Lab workshop will be to: identify specific opportunities to significantly reduce the cost of cell-free systems; establish acceptable standards for the fidelity and reproducibility; expand the range of capabilities in order to facilitate broader adoption of the technology; and identify and prioritize use-driven applications beyond human therapeutics.

This grant provides funding for research organizations and educational institutions to study the ecological and evolutionary factors influencing the spread of infectious diseases, particularly in low- and middle-income countries.

Please note that this program requests optional Notices of Intent, which are due via NSPIRES by March 28, 2024. See the full posting on NSPIRES for details. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

This funding opportunity provides financial support for research projects focused on forest management and ecosystem health in the Upper Mississippi River System, targeting non-federal partners with expertise in floodplain ecosystems.

This funding opportunity supports independent researchers in studying the prevention, diagnosis, and treatment of diseases related to military toxic exposures, benefiting Service Members, Veterans, and their families.

The long-range goal of the Research Training Groups in the Mathematical Sciences (RTG) program is to strengthen the nation's scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences, be they in academia, government, or industry. The RTG program supports efforts to improve graduate student research training and professional development through structured groups pursuing collaborative research. In addition to graduate student trainees working with faculty members, RTG supported research teams may, but are not required to, include undergraduate or postdoctoral trainees. The RTG program invites submissions in all fields within mathematical sciences; especially encouraged in 2024-2025 are those that align and integrate research in mathematics and statistics with emerging areas such asArtificial Intelligence, Biotechnology,Quantum Computing, and Cybersecurity.

This initiative seeks input from industry stakeholders, researchers, and communities to help define and promote sustainable maritime fuels that align with national decarbonization goals and reduce greenhouse gas emissions in the maritime sector.

Please note that this program requests optional Notices of Intent, which are due via NSPIRES by July 8, 2024. See the full posting on NSPIRES for details. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

The key aspects of this award are: Impact: The SRA is intended to support research designed to have a major impact on the health and well-being of melanoma survivors, their families, and/or caregivers. Impactful research will accelerate the movement of promising ideas into clinical applications or other real-world applications and advance the field of melanoma-specific quality of life and survivorship. Study Design: Applications should clearly articulate and justify the chosen study design. Studies proposing retrospective analyses or prospective enrollment should clearly describe the architecture of the study (e.g., descriptive, correlational, field experimental, meta-analyses) and the study population(s). The study population(s) should be representative of the people who are anticipated to benefit from the research. If applicable, questionnaires should be described in sufficient detail to justify interpretation of potential results. Melanoma Consumer Collaboration: For the purposes of the SRA, a melanoma consumer is defined as a melanoma survivor, family member, and/or caregiver who can provide lived experience expertise to the research project team. Applicants to the SRA are required to establish a collaborative research approach with the melanoma consumer community to maximize the impact and translatability of the research for the benefit of the intended melanoma community(ies). The research team must include at least one melanoma consumer or a melanoma-community supporting organization who will be integral to the planning, execution, and implementation of the proposed research. The role of the melanoma consumer collaborator(s) should include providing objective input on the research question being addressed; the study design, execution, and evaluation; and the potential impact of the research outcomes on the health and well-being of melanoma survivors, their families, and/or their caregivers. The melanoma consumer collaborator(s) should be active participants and integrated into the research team; their participation should not be limited only to passive activities (e.g., attending seminars or quarterly team meetings). Additional information and resources for establishing a collaborative research approach with the melanoma consumer community is provided below.Other Important Considerations:Collaborative Research Approaches: Collaborative research approaches create partnerships between scientific researchers and, for the purposes of the SRA, melanoma consumers to create knowledge useable by both sets of stakeholders. Recognizing the strengths of each partner, scientific researchers and melanoma consumers collaborate and contribute equitably on all aspects of the project, which may include needs assessment, planning, research intervention design, implementation, evaluation, and dissemination. Collaborative research approaches feature shared responsibility and ownership for the research project to ensure non-tokenistic involvement of the melanoma consumers within the research team. Research results are jointly interpreted, disseminated, and fed back to affected communities and in some instances may be translated into interventions or policy.Collaborative relationships with the melanoma consumer community may be established through integrating melanoma consumers and/or melanoma-community supporting organizations into research teams as co-researchers, advisors, and/or consultants. Examples for implementing collaborative research approaches are listed below, but each research team may pursue other options as appropriate for the proposed research: The research team includes at least one melanoma consumer who will provide advice and consultation throughout the planning and implementation of the research project. The consumer(s) should be able to speak to the needs of the melanoma consumer community, not just speak to their own personal experiences. The research team establishes partnerships with at least one community-supporting organization that provides advice and consultation throughout the planning and implementation of the research project. Community-supporting organizations may include advocacy groups or other formal organizational stakeholders that can speak to the needs of the melanoma consumer community. The research team assembles a melanoma consumer community advisory board. The advisory board may include melanoma consumers, a coalition of community-supporting organizations, or any combination thereof that provides advice and consultation throughout the planning and implementation of the overall program and/or individual research projects.

This funding opportunity supports not-for-profit organizations and educational institutions in the UAE to develop programs that strengthen U.S.-UAE relations through cultural events, space exploration initiatives, and entrepreneurship activities.

This funding opportunity provides supplemental support for NSF-funded researchers to collaborate with NIST scientists, enhancing their scientific projects in biological sciences, engineering, and mathematical and physical sciences through access to advanced measurement tools and expertise.

The U.S. Geological Surveys Northern Rocky Mountain Science Center (NOROCK) is offering a funding opportunity to a CESU Partner for research to assess distribution and threats to at-risk amphibians in the western USA. This research will focus specifically on how threats such as drought, non-native predators, habitat loss or transformation, environmental degradation, and pathogens are affecting the distribution and abundance of amphibians in the West. Field work will occur in the Northwest, Southwest, Rocky Mountains, and Great Plains, will occur primarily on BLM, NPS, USFWS, and USFS lands, and will focus on many species that are priorities to the Department of Interior and other partner agencies or stakeholders.

This funding opportunity provides financial support for research organizations within the Piedmont-South Atlantic Coast region to study the dynamics of avian influenza in wild bird populations, focusing on disease impacts and early warning systems.