Grants for Small businesses - State

Funding available through this RFA supports company formation, as well as early research and development of novel oncology therapeutics, devices, treatment-oriented information technology products, diagnostics, or tools. The objective of the SEED Award program is to start with an interesting technology and to progress it toward a commercially viable business opportunity, i.e., make it more attractive to private funding agents. Typically, applicants have completed the following activities: Identified a novel therapeutic, diagnostic technology, or clinical tool and shown a biological effect Conducted preliminary safety and toxicology testing (in the case of therapeutic agents) Shown the product can be manufactured at small scale or as a prototype Assessed the business opportunity and organized a business plan that begins to address key issues (clinical utility, target market, financial plan, IP strategy, technical challenges, etc.) and lays out a preliminary development plan (formulation, toxicology, scale up, IND-enabling studies, phase 1 clinical trials, regulatory pathway, etc.). Established a company

This program provides financial assistance to Vermont businesses involved in value-added processing of forest products to help cover the costs of necessary state and local permits.

This funding opportunity provides financial support to employers and apprenticeship sponsors in Colorado to develop or expand Registered Apprenticeship Programs, promoting a skilled and diverse workforce.

This opportunity invites midway operators to submit proposals for providing and managing rides, games, and concessions at the Great New York State Fair from 2025 to 2034.

This funding opportunity provides financial support for nonprofits, public-private partnerships, and industry consortia in North Dakota to develop and implement innovative autonomous agriculture projects that enhance technology, infrastructure, and workforce systems in the state.

Funding available through this RFA supports the ongoing research and development of innovative products, services, and infrastructure with significant potential impact on patient care. Generally, at this stage, the company has identified and characterized a lead compound; demonstrated efficacy in multiple translationally relevant animal models; completed pilot/dose ranging toxicology studies; determined the feasibility of a scalable, GMP compliant manufacturing process, including release assays; and identified a prototype formulation suitable for further development. The applicant is typically within one year from filing an IND/IDE or already in Phase 1. With appropriate justification, companies may use CPRIT funds to support the following: Studies that establish preclinical proof of concept (safety and efficacy) CMC/manufacturing development GLP safety studies to support INDs Phase 1 in humans to establish safety and a recommended dose for phase 2 Phase 2 studies to determine safety and efficacy in initial targeted patient population

This program provides financial assistance to North Carolina farmers affected by Hurricane Helene in 2024, specifically for agricultural losses not covered by other federal aid or insurance.

The Equitable Energy Future Grant Program, initiated by the Illinois Department of Commerce and Economic Opportunity, aims to promote renewable energy and energy efficiency projects in historically disadvantaged communities. With an estimated total program funding of $25.5 million, the program offers grants ranging from $250,000 to $1 million. These grants are designed to support equity investment eligible communities, provide on-the-job training, and facilitate the development of projects that benefit low-income households and community-based businesses. The program encourages projects that generate or save energy, with a significant focus on involving equity eligible contractors and workforce from CEJA or FEJA programs. Applicants are encouraged to leverage other funding sources to enhance cost-effectiveness and project impact.

This funding opportunity provides financial support to Pennsylvania farmers, agricultural processors, and service providers for adopting innovative technologies and sustainable practices to improve productivity and environmental stewardship.

This program provides funding to New Hampshire public entities and eligible private organizations to replace older diesel vehicles and equipment with cleaner alternatives, reducing harmful emissions and promoting sustainable transportation.

This funding opportunity is designed to support research projects that help California transition away from natural gas by exploring alternatives and strategies for decommissioning gas infrastructure in residential and commercial sectors.

This program provides financial support to small agribusinesses in urban areas of Missouri for projects that enhance infrastructure, improve local food systems, and promote sustainable urban agriculture.

All work supported under this Grant will focus on reducing health disparities for the populations across the state impacted by the high prevalence of cardiovascular (CVD), exacerbated by health inequities and disparities, social determinants, such as low incomes, poor health care, and unfair opportunity structures.  Financial Notes: Funds for the Umbrella Hub Arrangement come from the Centers for Disease Control and Prevention (CDC), A Strategic Approach to Advancing Health Equity for Priority Populations with or at Risk for Diabetes CDC-RFA-DP-23-0020 grant (230020).

This funding opportunity is designed to help mental health providers establish or expand intensive outpatient programs for children and adolescents in New York State, particularly in underserved areas, to improve access to essential mental health services.

This program provides financial assistance to small and medium-sized businesses in New Jersey that have suffered losses due to temporary closures along Route 80 caused by sinkholes.

This funding opportunity supports organizations that provide job skills training and employment pathways for justice-involved youth at the New Beginnings Youth Development Center in Washington, D.C.

The Illinois Environmental Protection Agency (Illinois EPA) offers the Section 319(h) Grant Program to address nonpoint source (NPS) pollution affecting Illinois’ water resources. This program, funded through the Clean Water Act, supports projects that prevent, eliminate, or reduce water quality impairments caused by NPS pollution. Prioritized projects include those implementing approved watershed-based plans or Total Maximum Daily Load (TMDL) Implementation Plans, with activities ranging from BMP implementation to monitoring and outreach efforts. The program encourages applications that demonstrate a comprehensive approach to NPS pollution control and offer sustainable environmental benefits. Grant renewed every year.

This grant program, overseen by the North Dakota Department of Agriculture in consultation with the North Dakota Department of Transportation (NDDOT), is dedicated to supporting infrastructure improvements for roadways and bridges. It aims to facilitate the development or expansion of new or existing value-added agriculture businesses by enhancing access and transportation infrastructure. Political subdivisions are invited to apply for funding to undertake corridor improvements on county and township roadways and improvements to bridges that provide access to value-added agriculture businesses. The program commits to awarding grants up to $1,250,000 or 80% of the project cost, prioritizing projects that demonstrate significant potential for economic impact on the agriculture sector. Rolling application. Deadline is 04/01/2025 unless funds are depleted earlier

Montana Fish, Wildlife & Parks accepts applications twice annually from landowners, watershed groups, and other nonprofits for the Future Fisheries Improvement Program. This program aims to fund habitat projects that benefit Montana's wild fish, focusing on improving or maintaining fish passage, restoring or protecting natural stream channels, riparian areas, essential habitats for spawning, and enhancing stream flow. Applicants must demonstrate public benefits and alignment with specific goals to improve fishing and protect wild fish populations. Preference is given to projects restoring habitats for native fishes. Funding covers design/build, construction, and maintenance costs, excluding administration and other indirect costs. Grant renewed every year. Grant Annual Summer deadline: May 15th

This program provides financial assistance to New Mexico-based meat processing facilities for modernizing operations and improving environmental compliance through targeted investments in waste management and technology upgrades.