Grants for Public Housing Authorities

This cooperative agreement would establish a Center for Home-based Child Care Research to support research about home-based child care (HBCC) in states, territories, This cooperative agreement would establish a Center for Home-based Child Care Research to support research about home-based child care (HBCC) in states, territories, tribes, and/or local community contexts. The purpose of the Center is to provide leadership, build research capacity in the field, and offer support in the development and facilitation of local research to improve understanding of HBCC settings and providers as well as access by the families who seek and utilize HBCC. This research center would promote sound research examining HBCC supply and the factors that support or suppress the availability of HBCC in communities. In addition, this Center would advance the fields understanding of HBCC engagement in public programs and quality improvement efforts. The Centers activities would build research and evaluation capacity in the field and support research in states, territories, and/or tribes that could inform local initiatives designed to sustain and strengthen HBCC.HBCC providers, or individuals and small business owners paid to provide child care in private residences or homes, are an essential segment of the child care landscape. They constitute the largest portion of the child care and early education (CCEE) workforce and serve the vast majority of children birth through school-age who are in regular nonparental care. It is critical for the Administration for Children and Families and for local communities to learn more about HBCC providers, both the individuals providing the care and the characteristics of the programs where they provide child care, in order to inform federal efforts and state, territory, tribal and/or local initiatives to increase access to safe and high-quality child care particularly for families with lower-incomes and working families. The Center would promote sound research examining HBCC and the factors that support or suppress the availability of HBCC in states, territories, and/or tribes. In addition, this Center would advance the fields understanding of HBCC providers engagement in publicly funded programs (e.g., child care subsidies, Head Start) and quality improvement efforts (e.g., Quality Rating and Improvement Systems (QRIS), quality initiatives (QI), and continuous quality improvement (CQI) initiatives). The Centers activities would build research and evaluation capacity in the field and support research in state, territories and/or tribes that could inform local initiatives designed to sustain and strengthen the supply of HBCC. This Center would ideally bring together a team that has experience investigating HBCC, evaluating Child Care and Development Fund (CCDF) program and policies, and assessing the needs and experiences of families with lower-incomes, in tribal communities, and of historically marginalized populations. This Center would be equipped to strengthen the ability of local research partnerships to conduct model research projects that effectively address questions concerning HBCC in local contexts, while contributing to broader understanding in the field about HBCC.

(Reissue PAR-21-058). The purpose of this Program Announcement (PAR) is to enable clinical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of biomarker measurements within the clinical population of interest to establish the positive and negative predictive values of the candidate biomarker consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed and analytically validated, and 3) the research and/or clinical need and potential context of use has been identified.

(Reissue PAR-21-056) The purpose of this Program Announcement (PAR) is to enable analytical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of analytical methods for biomarker measurements, including evaluation of the detection method, its performance characteristics, and the optimal conditions that will generate reproducibility and accuracy consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed, and 3) the research and/or clinical need and potential context of use has been identified.

This funding opportunity supports U.S.-based small businesses in the clinical validation of biomarkers for neurological or neuromuscular disorders, promoting inclusivity and collaboration while ensuring rigorous scientific standards for potential diagnostic and therapeutic applications.

This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field;apos;s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.

This funding opportunity supports early-stage researchers in cancer control and population sciences to explore innovative ideas that can significantly advance cancer research and improve healthcare delivery.

This grant provides funding and protected time for U.S. postdoctoral researchers and junior faculty to conduct mentored research in low- and middle-income countries, focusing on global health priorities.

This funding opportunity supports interdisciplinary research teams in the U.S. working to tackle critical issues at the intersection of HIV and substance use disorders, with a focus on prevention, understanding, and treatment strategies.

The Office of Planning, Research and Evaluation (OPRE), within the Department of Health and Human Services' (HHS) Administration for Children and Families (ACF), plans to solicit applications for cooperative agreements under the Child Care and Development Fund (CCDF) Lead Agency Data and Research Capacity: Planning Grants (Phase I). These projects are meant to support partnerships between CCDF Lead Agencies and researchers to develop and improve state, territory, and Tribal data systems and build the capacity of CCDF Lead Agencies to collect, analyze, and use data to guide child care policy decisions and program improvement efforts. Sponsored projects will work in collaboration to: (1) assess the current data and research capacity of the CCDF Lead Agency; (2) develop questions of interest to investigate state, territory, and Tribal child care policies and practices; (3) develop logic models to identify the data needed to address the questions of interest; (4) identify data sources available to answer questions of interest and assess the accessibility of those data; (5) identify possible data sources from other state, territory, Tribal, and local data systems for linking; (6) determine whether there is a need to collect data to answer policy-relevant questions; and (7) address the barriers to collecting, analyzing, and using data to inform child care policy decisions. These projects are intended to build the capacity of CCDF Lead Agencies to use data, including data on children, families, the workforce, and providers that participate in the child care subsidy system, to make data-informed decisions to improve child care policies and practices. These 18-month projects, with one project and budget period, will fund a planning phase to develop a research plan to address questions of interest to the CCDF Lead Agency, including a plan for identifying, linking, and using state, territory, and Tribal data to inform child care policy decisions. These planning projects may be followed by a second competition (Phase II), under a separate Notice of Funding Opportunity, to support execution of the research plans to develop and improve state, territory, and Tribal data systems. Projects must be conducted through partnerships between CCDF Lead Agencies (i.e., states, territories, Tribes, or local subsidy administering agencies) and researchers from institutions of higher education, within the state agency, research organizations, and/or other organizations with proven expertise conducting policy research. Applications are invited from CCDF Lead Agencies, institutions of higher education, research organizations, and other organizations with proven expertise conducting policy research. The research supported by this program should be collaborative from start to finish. The CCDF Lead Agency and their research partners must work together to assess the current data and research capacity of the CCDF Lead Agency and develop a feasible plan for identifying, linking, and using data to address questions of relevance to the CCDF Lead Agency. Sponsored projects will be expected to participate in a Consortium that will meet and communicate regularly to identify opportunities for coordination, such as to share information on facilitators and barriers to identifying and using data to inform child care policies and methods for linking data across systems, and to develop collective expertise and resources for the field. The Consortiums collaboration will support research capacity and learning within individual projects and across award recipients. Funding is subject to availability of funds and the best interests of the federal government.

The Unaccompanied Children Lived Experience and Youth Engagement Support Program is forecasted to provide funding to establish, manage, and evaluate a Lived Experience Community Council and Lived Experience Leadership Academy comprised of former unaccompanied children and individuals who sponsored children from ORR care. The recipient shall recruit, identify, orient, and train lived experience experts that reflect the demographic diversity (e.g., age, language, etc.) and varied experiences and circumstances (e.g., pregnant/parenting youth, survivors of human trafficking, etc.) of former unaccompanied children and sponsors. Therefore, prior experience developing programming centering lived experience and youth voice and/or supporting unaccompanied children, sponsors, and reunified families is highly desirable. These lived experience bodies have two objectives. The first is to collect feedback from former unaccompanied children and reunified families about their first-hand experience integrating to the United States. The second is to positively impact the lives of Community Council and Leadership Academy members by building their capacity to serve as leaders within their respective communities. The recipient shall provide the necessary resources, such as personnel, to support the implementation of the lived experience bodies. Task areas will include: a) development of the Community Council implementation plan and Leadership Academy curriculum; b) development of a web-based application; c) selection of eligible candidates to the appropriate lived experience body; d) project management; e) interpretation and translation services for, and during, community meetings; f) secure technology for members to participate in virtual meetings; g) compensate members for their time; h) as separate cohorts, coordinate and implement Washington Weeks for the Community Council and Leadership Academy to meet with government leaders and relevant stakeholders, and i) disseminate to the ORR-funded network feedback obtained through the lived experience bodies' work that centers youth voice and lived experience.

This Notice of Funding Opportunity (NOFO) invites applications for sites to participate in the Genomic Medicine eConsult Research Network, hereafter referred to as the eConsult Network. The eConsult Network will consist of 2-3 sites working with NHGRI to conduct research on the impact of and methods for implementing regional clinician-to-clinician genomic medicine eConsult services. Specifically, sites will be funded to research how to best design, develop, and implement regional genomic medicine eConsult services; provide outreach to potential users, including those at underserved settings; and assess the impact on key stakeholders while developing successful implementation strategies and resources that can be broadly shared and adopted.

This funding opportunity supports high-risk, multi-center observational studies aimed at advancing research on diabetes, digestive diseases, kidney disorders, and other related health conditions, encouraging diverse institutions to collaborate and innovate.

This funding opportunity supports high-risk, multi-center clinical trials aimed at addressing significant health issues related to diabetes, digestive diseases, and kidney disorders, encouraging diverse institutions to apply for impactful research that can transform clinical practices.

This funding opportunity supports researchers in planning high-risk, multi-center clinical studies focused on kidney, digestive, diabetes, and metabolic disorders, helping them develop essential protocols and administrative frameworks before conducting the actual trials.

This funding opportunity supports institutions in developing clinician scientists through structured research training in substance use and addiction, enabling them to pursue independent research careers.

This funding opportunity supports researchers and institutions conducting clinical trials and studies to improve stroke treatment, recovery, and prevention through collaboration within a national network.

This funding opportunity supports early stage researchers in pursuing innovative and high-risk scientific projects that significantly diverge from their previous work, without the need for preliminary data.

The National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the TrialNet Clinical Network Hub (HUB). The purpose of this Notice of Funding Opportunity (NOFO) is to continue support for the Type 1 Diabetes TrialNet Clinical Network Hub (HUB), a screening and clinical activities coordination unit for clinical trials focusing on the prevention of and early intervention in type 1 diabetes (T1D). The main objective of the HUB is to increase the efficiency and productivity of the TrialNet network by providing coordination of communications and outreach and developing new tools and approaches to increase screening, recruitment and retention. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Spring 2024 with an expected application due date in Summer 2024. This NOFO will utilize the U01 activity code. Details of the planned NOFO are provided below.

The National Cancer Institute (NCI) intends to issue the U54 Specialized Programs of Research Excellence in Cancer Health Disparities and Minority Health (CHD-MH SPORE) notice of funding opportunity (NOFO). The program will support a network of multidisciplinary, multi-institutional U54 CHD-MH SPOREs, which are multi-project awards uniquely focused on health disparities and/or minority health translational research for improved prevention, early detection, diagnosis, and treatment of cancer in populations who are underserved. U54 CHD-MH SPOREs can investigate more than one cancer type in underserved populations, including groups of highly related cancers (e.g., gastrointestinal or head and neck). The research supported through this program must be translational and must stem from research on human biology, addressing the interplay of various determinants of health with the biology of the disease. U54 CHD-MH SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant, which may include a clinical trial. This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications. The NOFO is expected to be published in late winter 2024 with only one expected application due date in late September 2024.

The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose to establish a national Open Measurement Coordinating Network for Non-Pharmacological Alzheimer's Disease (AD) and AD-related Dementias (ADRD) Primary Prevention Trials. The Network will serve as a centralized hub for developing, validating, standardizing, and disseminating measures and measurement methods for AD/ADRD primary prevention trials. It will incorporate measures and measurement methods across neuropsychological, biomarker, and functional domains to meet the goal of primary prevention of AD/ADRD centered around brain health equity. Brain health equity is the fair distribution of brain health determinants, outcomes, and resources within and between segments of the population, regardless of social standing. Measures and methods of interest will test outcomes and mechanisms of action in settings customized for individuals with different needs and linked to real-world function. Applications must explain how the platform will meet evolving community needs and partner with other NIA-funded programs. Applications must also describe activities that will achieve the following objectives: Develop an organizational and governance structure to support the administration, innovation, and dissemination functions of the Network. Propose activities to establish a framework that will facilitate the development of innovative strategies for standardization and use of methods and measures across NIA-supported projects and support activities for the discovery and development of innovative and novel measures and data. Disseminate Network resources and products to the broader AD/ADRD research community. Ensure that all measures and methods development and validation occurs in a racially, ethnically, geographically, and diagnostically diverse set of participants, including members of NIH-defined Health Disparity Populations. This also includes establishing the acceptability and feasibility of using the proposed instruments in both cognitively normal individuals and persons living with cognitive impairment (PLWCI), including subjective cognitive decline. NIA is particularly interested in proposals that advance equity for populations disproportionately impacted by AD/ADRD. For example, Black and Hispanic Americans have a higher prevalence of AD/ADRD compared to non-Hispanic White Americans. Resources, including measurement instruments, methods, algorithms, code, documentation, and normative data will enable other, future measures and methods development projects that support AD/ADRD primary prevention research needs. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in early 2024 with an expected application due date in Spring/Summer 2024. This NOFO will utilize the U24 activity code.