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Grants for Small Businesses

Explore 4,109 grant opportunities available for Small Businesses

Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 18, 2026

Date Added

Jun 10, 2025

This funding opportunity supports researchers and organizations working to improve the readiness for clinical trials in rare diseases by developing biomarkers and understanding disease progression.

Health
Nonprofits
The Nicor Gas Illinois Innovator Award
$25,000
Evergreen Climate Innovations
Private

Application Deadline

Not specified

Date Added

Jun 10, 2025

This grant provides $25,000 and mentorship to early-stage climate technology companies in Illinois, helping them develop innovative solutions that positively impact the environment.

Environment
For profit organizations other than small businesses
Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports innovative research to identify and develop treatments for central nervous system complications in individuals living with HIV, inviting a diverse range of applicants including governments, nonprofits, and educational institutions.

Health
State governments
California Jobs First Catalyst Funding
$750,000
California Jobs First
Private

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity provides financial support for projects in Orange County that advance pre-development activities aimed at creating good-paying jobs and promoting economic equity in the transition to a clean energy economy.

Infrastructure
Nonprofits
Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports a national resource for clinician-scientists dedicated to aging research, promoting collaboration, mentorship, and interdisciplinary projects to improve care for older adults.

Health
State governments
Rooted Pathways Grant Program 2025
$55,000
First Peoples Fund (FPF)
Private

Application Deadline

Jun 20, 2025

Date Added

Jun 9, 2025

This program provides financial support to Native-led arts and cultural organizations in the U.S. to strengthen their operations and promote Indigenous arts and culture.

Arts
Nonprofits
Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity supports research on how genetic variations interact with each other and environmental factors to influence biological outcomes, inviting a wide range of institutions and organizations to collaborate on innovative studies.

Health
Native American tribal organizations
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (UT1/UT2) Clinical Trial Not Allowed
$1,972,828
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2025

Date Added

Jun 7, 2025

This funding opportunity supports U.S.-based small businesses in developing and manufacturing therapeutic extracellular vesicles for regenerative medicine applications, focusing on tissue and organ repair.

Health
Small businesses
Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity supports research centers that will develop predictive models to understand how genetic variations impact genome function, contributing to a collaborative network aimed at advancing human health through genomic research.

Health
State governments
GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity is designed to establish a central hub for coordinating and sharing data and resources related to rare disease research, inviting a diverse range of organizations, including universities, nonprofits, and government entities, to apply for support in advancing innovative genetic research.

Health
State governments
PRIMED-AI: Validation Center (U54 Clinical Trial Not Allowed)
$3,900,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity supports the establishment of a center dedicated to validating AI-based clinical decision support tools that integrate imaging and health data, aimed at improving personalized healthcare for individuals with significant health conditions.

Health
County governments
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
$1,972,828
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2025

Date Added

Jun 7, 2025

This funding opportunity supports small U.S.-based businesses in developing and scaling innovative therapies using extracellular vesicles for regenerative medicine applications, such as tissue and organ repair.

Health
Small businesses
Title V Competitive Sexual Risk Avoidance Education
$450,000
U.S. Department of Health & Human Services (Administration for Children ; Families - ACYF/FYSB)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This grant provides funding to local organizations in underserved states and territories to implement educational programs that encourage youth aged 10 to 19 to avoid non-marital sexual activity and promote healthy life choices.

Youth
Nonprofits
FedEx E-Commerce Learning Lab Program
$5,000
Accion Opportunity Fund
Private

Application Deadline

Not specified

Date Added

Jun 6, 2025

This program provides funding and resources to U.S.-based small businesses selling packaged products, helping them develop e-commerce skills and grow their online sales.

Business and Commerce
For profit organizations other than small businesses
Tire Incentive Program
$650,000
California Department of Resources Recycling and Recovery
State

Application Deadline

Not specified

Date Added

Jun 6, 2025

This program provides financial incentives to California manufacturers who use recycled tire materials in their products to promote sustainability and reduce waste.

Environment
Small businesses
DoD Toxic Exposures Investigator-Initiated Research Award
$770,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 16, 2025

Date Added

Jun 6, 2025

This funding opportunity supports independent researchers in studying the prevention, diagnosis, and treatment of diseases related to military toxic exposures, benefiting Service Members, Veterans, and their families.

Science and Technology
City or township governments
Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 14, 2026

Date Added

Jun 5, 2025

This funding opportunity provides financial support for early-stage researchers to conduct small-scale studies that inform public health policies related to tobacco use and regulation.

Health
Nonprofits
Community Sleep Health and Public Awareness Grant
$50,000
Academy of Sleep Medicine Foundation (AASM Foundation)
Private

Application Deadline

Not specified

Date Added

Jun 5, 2025

This grant provides funding for nonprofit organizations to implement community-focused projects that promote sleep health and improve access to sleep disorder care, particularly in underserved populations.

Health
Nonprofits
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
$1,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 18, 2025

Date Added

Jun 5, 2025

This funding opportunity provides financial support to academic and research institutions for establishing interdisciplinary centers that advance research on the impact of environmental factors on human health and promote community engagement in public health initiatives.

Environment
State governments
Finish Line Grant Program
$75,000
Aurora Regional Economic Alliance Foundation
Private
Rolling

Application Deadline

Not specified

Date Added

Jun 5, 2025

This program provides financial assistance to small commercial and mixed-use property owners and tenants in Aurora, Illinois, for essential property improvements and renovations.

Infrastructure
Small businesses

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