Grants for Native American tribal organizations - Food and Nutrition

The purpose of this research is to systematically evaluate the diastereomeric composition of LEQVIO (Inclisiran), an FDA-approved, N-acetyl galactosamine (GalNAc)-conjugated siRNA drug, and to understand the biological/pharmacological activity of each diastereomer in LEQVIO through stereo chemically controlled synthesis and biological activity assessment using in vitro and animal models. The proposed studies will focus on 1) synthesis of each diastereomer of LEQVIO (Inclisiran) in stereo chemically pure form; 2) assessment of the biological activity of each stereo chemically pure diastereomer in inhibiting PCSK9 activity using in vitro assays and in a transgenic mouse model; 3) development of analytical methods to identify and characterize the stereochemical structure of each diastereomer in LEQVIO; and 4) assessment of the individual contribution of each diastereomer to the overall pharmacological activity of LEQVIO. Tools developed in this research can also be applied to other similar GalNAc-conjugated siRNAs specifically, and other siRNAs in general. Knowledge gained from this research will also contribute to the sameness evaluation of generic siRNAs, and to the quality control of oligonucleotide drugs.

The GOODS Program is a grant opportunity provided by Greater Good Charities. It aims to distribute food, essential supplies, clothing, housewares, toys, and more to pets and people in need across the world. The program helps various constituents including pets (homeless and owned), families facing economic hardships, unhoused populations, military veterans, domestic violence survivors, victims of disasters, and displaced persons. The GOODS Program works by sourcing and managing excess, re-branded, and short-dated food and supplies from donors such as manufacturers, distributors, and retailers. These products are then made available to qualified distribution groups called Ambassadors who ensure they reach the organizations in need known as Recipients. The program operates through a sustainable hub and spoke model similar to a food bank where goods are donated but costs are covered by handling fees and donations. To apply as a Recipient organization, interested parties can locate the nearest Ambassador on the program's website and apply directly through their website. For general inquiries or to inquire about grants and services, individuals can contact Greater Good Charities through their website or send checks to their designated address in Seattle, WA.

The Connection, Health, & Equity through Food (CHEF) Grant Program is a collaborative initiative across Maine, New Hampshire, Vermont, Eastern Massachusetts, and Upstate New York, administered by the Maine Council on Aging. The program's core mission is to increase older adults’ equitable access to healthy food and social connection, aligning with a broader goal of addressing systemic issues like food insecurity and social isolation. This grant program seeks to support older adults by fostering programmatic infrastructure, expanding existing programs, and launching innovative new initiatives that cater to their food and social connection needs. The target beneficiaries of the CHEF Grant Program are primarily older adults, with a specific focus on underserved and marginalized populations. These include BIPOC (Black, Indigenous, People of Color), LGBTQ+, women, veterans, people living with disabilities, and individuals residing in rural communities. The program's impact goals are centered on enhancing the quality of life for these older adults by improving their access to nutritious food and opportunities for social engagement. Projects that serve diverse older people, veterans, and older people living with disabilities are given priority. The CHEF program prioritizes finding solutions to the root causes of food insecurity and social isolation. These root causes include poverty, transportation barriers, rurality, and language barriers. While the grant does not explicitly detail the foundation's strategic priorities or a formal theory of change, the emphasis on equitable access, addressing systemic issues, and supporting vulnerable populations suggests a strategy focused on community-based interventions and empowerment. The program's design indicates a theory that by investing in local organizations and initiatives, significant improvements can be made in the well-being of older adults. Expected outcomes include increased access to healthy food for older adults, enhanced social connections within communities, and a reduction in the prevalence of food insecurity and social isolation among the target populations. While specific measurable results are not explicitly outlined, the program's focus on data for older people served (50.1% of the overall population served) suggests an intent to track the reach and impact on the primary beneficiary group. The grant duration is not mentioned, but the anticipated grant size of $2,000 – $10,000 for most grants indicates support for projects with tangible, localized impacts.

This funding opportunity provides financial support for organizations to host conferences and scientific meetings that address important public health issues relevant to the FDA's mission.

This funding opportunity supports predoctoral students in dual-degree programs at institutions without NIH-funded training programs, helping them pursue research and clinical training to become future physician-scientists.

This funding opportunity supports the development of innovative tools and technologies aimed at advancing research and treatment in kidney, urologic, and hematologic diseases, encouraging projects that push scientific boundaries and have broad applications beyond individual research interests.

The Resilient Food Systems Infrastructure (RFSI) program, funded by the USDA, allocates approximately $2 million for infrastructure grants to Vermont businesses and organizations aiming to strengthen local and regional food systems. The grants support projects that improve the aggregation, distribution, manufacturing, processing, storing, transporting, and wholesaling of Vermont food products. This track encourages development of Vermont value-added products and promotes fair wages and job creation. A 50% match is required, which can be reduced to 25% for historically underserved farmers. Grants range from $100,000 to $500,000 and are available from fall 2024 through February 2027.

The Food and Drug Administration's (FDA), Center for Drug Evaluation and Research (CDER), Office of New Drugs (OND), is announcing this Funding Opportunity Announcement (FOA) for a Cooperative Agreement. The proposed work directly supports the U.S. FDAs stated goal of protecting public health from unacceptable risks from nitrosamine impurities in human drugs. Although significant experimental and policy/regulatory initiatives have been undertaken in this area, there remains a need for further research into and development and refinement of translational and implementable practices that will protect the public against nitrosamine risks while ensuring continued safe access to critical therapeutic drugs. The aim is to improve the safety of human drugs with potential nitrosamine impurity liabilities. In addition to the work outlined above, the award recipient will assess how best to ensure that this research and practices development continues among industry members, non-profits, and/or academic institutions once the FDA funding for this cooperative agreement ends.

The Cow Creek Umpqua Indian Foundation offers grant opportunities for nonprofit 501(c)(3) organizations and local governmental bodies within Douglas County, Oregon. Focusing on Basic Needs, Abuse Prevention and Intervention, Education, Health and Wellness, and Community Support, the Foundation aims to fund projects that have a significant impact within the communities of Coos, Deschutes, Douglas, Jackson, Josephine, Klamath, and Lane Counties. With a maximum grant amount of $15,000. The Foundation emphasizes support for small grants that contribute meaningfully to the project or program, limiting organizations to one proposal per year unless specified otherwise. A final report is required from all grantees before reapplying. Grant renewed every year. Grant Annual Fall opening/closing deadlines: March 2nd to September 1st

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative multidisciplinary and multi-level research designed to develop and/or test interventions to optimize care of persons with Type 2 diabetes from populations with health/health care disparities concordant with evidence-based guidelines. NIH-designated health disparity populations include racial and ethnic minorities (Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asians, Native Hawaiians and other Pacific Islanders), sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations. Proposed projects would be expected to develop and/or test patient-centered strategies, which in addition to optimal glycemic control, would aim at completing other recommended guidelines (e.g., annual eye/foot and urine albumin exam, optimal blood pressure control, intake of ACEIs or ARBs/statin/aspirin and influenza/pneumonia vaccines).

This Notice of Funding Opportunity (NOFO) invites applications from institutions/organizations that propose to establish a Research Resource Center (RRC) for the NIDDK Nutrition Obesity Research Centers (NORC) Program. The NORC Program consists of eleven Centers across the nation that support and enhance the national research effort in nutrition and obesity through cutting-edge basic, clinical, translational, and health disparities research in nutrition science and obesity. In collaboration with the existing NORC program, the RRC will (1) provide administrative support for the entire NORC Program, (2) establish and curate a NORC Program website and centralized repository of research resources , (3) implement a multipronged approach to support and grow the early-to-midcareer research workforce, including individuals from diverse backgrounds, with a goal of maximizing national outreach and impact, (4) administer and manage a NORC Opportunity Program to address gaps and promote collaboration, and (5) manage a Pilot and Feasibility Program.This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.

This Funding Opportunity Announcement (FOA) invites applications to develop and implement Phase Ib to III clinical trials of promising pharmacological and non-pharmacological interventions that may prevent, delay, or treat the symptoms of Alzheimer's disease (AD) and other age-related dementias using the Alzheimer's disease Clinical Trials Consortium (ACTC) trial coordination and management infrastructure.Research Objectives Utilizing the ACTC, the goal of this FOA is to invite research grant applications that provide clinical testing (Phases Ib-III) of promising pharmacological and/or non-pharmacological interventions for cognitive and neuropsychiatric symptoms in individuals with AD or other aging-related dementias across the spectrum from pre-symptomatic to more severe stages of disease. Working with the ACTC is a cooperative venture between the applicant, the NIA, and the ACTC network. NIA and the ACTC leadership will provide guidance to potential applicants. Potential applicants are strongly encouraged to contact NIA Scientific/Research Contacts (see Agency Contacts, Section VII) and the ACTC study team in order to discuss the feasibility of conducting the proposed trial through the ACTC infrastructure before considering an application. The ACTC infrastructure is welcoming of the following: Academic and industry applicants Pharmacological and non-pharmacological interventions Applications are encouraged that propose the following: Testing candidate therapeutic compounds against novel therapeutic targets Testing repurposed drugs derived from data-driven approaches, including candidates coming from NIA's translational bioinformatics FOA (PAR-17-032) Logistical guidance: Potential applicants undergo initial vetting of proposed study by the ACTC protocol evaluation committee and final review by the steering committee. Applicants should contact the ACTC study team at least 5 months prior to their desired NIA submission cycle. Contact details and more information may be found at actcinfo.org. Applications should anticipate using a centralized IRB. Applicants should be aware of the data and resource sharing requirements. The use of common contract language is strongly encouraged. Note, the ACTC infrastructure is not appropriate for: Single site clinical trials Routine Phase Ia first-in-human Clinical trials funded from this FOA will be implemented through the ACTC. The clinical trials approved for funding will develop their final protocols in conjunction with the ACTC. All ACTC sites will have the option to request participation and will be selected based on their capabilities specific to the individual protocols. Investigators are strongly encouraged to collect blood and other biosamples for future genomic and other 'omic' analyses aimed at interrogating treatment responsiveness and examining predictors of decline and progression. See Section VIII. Other Information for award authorities and regulations.

This funding opportunity provides significant financial support to U.S. higher education institutions and research organizations with established HIV/AIDS research programs, enabling them to enhance their research infrastructure and foster interdisciplinary collaboration in the fight against HIV/AIDS.

This funding opportunity provides financial support to research institutions for developing and sharing essential resources to advance the study of Polycystic Kidney Disease, fostering collaboration and innovation in the field.

The Idaho Department of Environmental Quality (DEQ) is offering 2025 Source Water Protection Grants to fund projects aimed at safeguarding public drinking water sources. These grants are designed to support activities that reduce the risk of contamination to drinking water, ensuring the long-term quality and safety of Idaho's water supply. The program aligns with the federal Safe Drinking Water Act, specifically Section 1452, which provides funding for source water assessment and protection efforts. By focusing on preventative measures and community-wide protection, the DEQ seeks to uphold its mission of protecting human health and the quality of the environment. The primary beneficiaries of these grants are public water systems, local government units, special districts, associations, nonprofit organizations, educational institutions, and tribes within Idaho. The impact goal is to improve the protection of one or more public water supply sources by reducing the threat of contaminants. Projects are expected to provide long-term benefits to source water quality, ultimately ensuring safe and reliable drinking water for communities across the state. The program prioritizes efforts that go beyond normal operational standards and existing infrastructure deficiencies, focusing on proactive and sustainable solutions. The program's priorities and focus areas are diverse, encompassing various strategies to protect source water. These include contaminant source identification through research, contaminant pathway removal such as the closure of abandoned wells, contaminant removal through hazardous waste collection and pollution prevention, and contaminant management via the implementation of best management practices and structures to divert contaminated runoff. Additionally, the grants support the restoration and conservation of ecological functions within source water protection areas, as well as education and information sharing campaigns to raise awareness. Security measures to protect physical extraction structures like wells, springs, and intake structures are also eligible, including fencing, gates, alarms, signs, cameras, locks, and lights directly related to source water area protection. Expected outcomes include a measurable reduction in the risk of drinking water contamination, improved source water quality, and enhanced long-term protection for public water supplies. The grants anticipate fostering a proactive approach to water resource management, leading to more resilient and secure drinking water systems. With up to $750,000 available for project funding in SFY2025, and a maximum request of $24,000 per project proposal, the program aims to support numerous initiatives that collectively contribute to a safer and more sustainable water future for Idaho. The emphasis on community public water supply systems and aquifer/watershed-wide protection efforts reflects a comprehensive strategic approach to water resource stewardship.

The Pennsylvania Department of Agriculture offers Simplified Equipment-Only Grants under the Resilient Food Systems Infrastructure Program, aimed at strengthening food system infrastructure. These grants provide financial support solely for equipment purchases necessary for food production and processing. Each grant ranges from $10,000 to $100,000 and does not require cost-sharing or matching. Recipients must substantiate equipment costs through documentation such as contracts or quotes. The program emphasizes enhancing the capabilities of small and mid-size producers and benefits diverse groups including underserved and veteran farmers. Projects must be completed between July 1, 2024, and June 30, 2026.

This funding opportunity provides financial support to public and nonprofit organizations to deliver comprehensive primary health care services in underserved communities across the United States.

This funding opportunity provides financial support to organizations implementing strategies to prevent diabetes and improve health equity for populations at risk, focusing on statewide, local, or multisectoral approaches.

Fiscal Year 2024 Key Objectives Application proposals must include at least one of the following three objectives identified below. Proposals may contain more than one objective. As noted in Section 4, applicants must map their proposed activities and indicators measuring success to the objective(s) using the Activities/Indicators Tracker. If awarded, grantees will be required to use the FNS-908 Performance Progress Report to report on progress towards activities that align with the required objective(s) listed on the Activities/Indicators Tracker. Carefully considering proposed activities and indicators will prepare grantees for their performance progress reporting requirements if awarded. The project examples aligned with each objective listed below are only suggestions. A PTIG project may assist State agencies in making investments in systems to improve efficiency, provide excellent customer service, and meet Federal standards as they face unprecedented operational challenges. FNS welcomes other projects that support these objectives and encourages applicants to propose innovative ideas to solve both common and unique problems associated with SNAP application and eligibility processes. 1. Modernize SNAP customer service and client communication to improve accessibility, transparency, and responsiveness in processing applications and determining eligibility. 2. Improve administrative infrastructure and day-to-day SNAP operations in processing applications and determining eligibility. 3. Invest in technology and systems to encourage cross collaboration and cross enrollment between SNAP and other Federal, State, and local assistance programs. Please read the full announcement for additional details.

This grant provides funding to Indian Tribes and authorized tribal organizations to develop tailored AmeriCorps programs that address community needs and enhance local capacity for future service initiatives.