Grants for Public housing authorities - Health

This funding opportunity provides financial support for projects that promote healthy relationships and marriage education for adults, with a focus on enhancing family stability and economic well-being.

This grant provides funding for innovative researchers to explore groundbreaking ideas that could transform the prevention and treatment of HIV/AIDS, particularly among individuals with substance use disorders.

The "Blueprint MedTech Translator" grant aims to fund researchers to develop and test therapeutic and diagnostic devices for nervous or neuromuscular system disorders, with support for clinical trials, safety testing, design verification, and regulatory approvals, while also providing access to expert consultants and specialized research organizations.

This program provides funding to public organizations like libraries, schools, and nonprofits in underserved areas to purchase internet-enabled devices and establish public Wi-Fi, promoting digital access and inclusion.

The objective of this research proposal is to develop physiologically based pharmacokinetic (PBPK) model-based mechanistic in vitro in vivo correlations (IVIVCs) for two major types of long acting injectables (LAIs) such as crystalline suspensions and polymer-based implants by considering their distinct characteristics. The goal of the project is to develop a bottom-up mechanistic PBPK model for these two LAI categories by accounting for the influence of critical formulation attributes of each LAI drug product type to predict its in vivo release mechanism. The model formulation parameters and relevant physiology should be informed with suitable in vitro and in vivo experiments. A suitable preclinical animal model can be used to validate the PBPK model based IVIVCs for both LAI suspensions and polymer based implants. The use of PBPK modelling provides a unique opportunity to understand how the physicochemical properties of drug molecules/polymer, implant specific properties, critical formulation attributes, and physiology, among other things, influence the in vivo release mechanisms of LAI drug products and their disposition characteristics. Moreover, once developed, a mechanistic PBPK model can help to define the 'safe space' for critical formulation attributes relevant to the reference listed drug (RLD) product, explain sources of PK variability and extrapolate predictions to human subjects by leveraging animal model data and by accounting for species-specific physiological differences.

This funding opportunity supports research projects that investigate the relationship between HIV and aging, focusing on improving health outcomes for older adults living with HIV, particularly in diverse and underserved populations.

This funding opportunity supports research projects that develop and implement effective tobacco use treatment services for cancer survivors across diverse clinical settings, with a focus on equitable access and reducing health disparities.

This funding opportunity supports graduate students from diverse backgrounds in neuroscience to complete their Ph.D. and transition into postdoctoral research positions, promoting career development and research training.

This funding opportunity provides financial support for early-career researchers from diverse backgrounds to develop their skills in cancer research under the mentorship of experienced scientists, without leading independent clinical trials.

This grant provides funding for research to develop and test combined neuromodulation and behavioral treatment strategies for individuals with Stimulant Use Disorder, particularly targeting those with vulnerable traits like low executive function and impulsivity.

This funding opportunity supports research to improve stem cell-derived islet cells for transplantation therapies, targeting interdisciplinary collaborations among scientists and institutions focused on diabetes and cell biology.

The "Limited Competition: NCI National Clinical Trials Network - Network Group Statistics and Data Management Centers" grant is designed to provide financial support to current awardees for maintaining centers that offer statistical expertise and data management for large-scale, multi-center oncology clinical trials aimed at advancing cancer treatment through precision medicine approaches.

The purpose of the Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01) is to provide support and protected time (three, four, or five years) for an intensive, supervised career development experience in biomedical, behavioral, and social science research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing and that will lead to research independence. Research projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) as mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31.

NLM wishes to accelerate the availability of and access to secure, complete data sets and computational models that can serve as the basis of transformative biomedical discoveries by improving the speed and scope of the curation processes.NLM wishes to accelerate the availability of and access to secure, complete data sets and computational models that can serve as the basis of transformative biomedical discoveries by improving the speed and scope of the curation processes. This Funding Opportunity Announcement is focused on automating curation of biomedical digital assets in support of Goal 1. Objective 1.1 of the NLM Strategic Plan 2017-2027: An important research direction will develop strategies for curation at scale." The ability to re-use, integrate or add to existing data sets will open new avenues of opportunity and can speed discoveries that will improve health. But this promise will go unrealized without advances in automated and autonomous curation. Objective 1.2: Automatic, autonomous curation strategies will allow for operational efficiency as well as accelerate the speed of discovery Digital curation involves characterizing, annotating, managing, and preserving digital assets such as research data sets, computational and other types of models, reusable visualization tools, and other digital assets. Proficient curation of digital assets maximizes their reuse potential, mitigates risk of obsolescence, reduces the likelihood that their long-term value will diminish or be lost, and helps assure reproducibility of research. The evolving digital ecosystem supports data-driven biomedical discovery by providing access to large quantities of biomedical and health-related data, to computational models and to open source software and code. The scope, scale and heterogeneity of digital data alone are vast, ranging from genome sequences to biomedical images, from observational health findings to environmental measurements, from family histories to sensor readings from personal trackers. As the amount and complexity of digital assets continue to grow, manual curation will not scale to meet future needs. At the same time, as researchers make research data sets, models and other tools available for new uses or re-analysis, it is important to minimize duplication and simplify the process of finding, managing, visualizing and mining all types of digital assets. To help researchers who want to find, interoperate and use these data sources to make new discoveries, and to share their findings so others can build upon them, the purpose of this funding announcement is to encourage applications for new approaches that (1) increase the speed and assure quality and security of storage techniques, retrieval strategies, annotation methods, data standards, visualization tools and other advanced data management approaches and (2) improve our ability to make biomedical data and other digital research assets findable, accessible, interoperable and reusable (FAIR).

The purpose of the Pathway to Independence Award in Tobacco Regulatory Research (K99/R00) is to increase and maintain a strong cohort of new and talented independent investigators conducting research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions

This grant provides funding for researchers to develop and test advanced imaging tracers that can help understand and treat mental health and neurodegenerative disorders in humans.

The purpose of this initiative is to: 1.Support mining of SCORCH data to identify cell types, transcripts, enhancers, or transcriptional networks that play a role in HIV/ART or SUD molecular responses 2.Support functional validation studies (e.g. epigenomic or transcriptomic manipulation, high throughput secondary screening, etc.) to confirm or deny a biological role for data-mined cell types, transcripts, enhancers, or transcriptional networks in HIV/ART or SUD molecular responses 3.Provide foundational knowledge for understanding SUD and/or HIV/ART molecular mechanisms and to generate validated targets that could serve as a foundation for new SUD or HIV therapeutics (including NeuroHIV cognitive phenotypes)

This funding opportunity is designed to support researchers exploring how RNA modifications affect brain aging and contribute to Alzheimer's disease and related dementias.

The National Institute of Neurological Disorders and Stroke (NINDS), intends to publish a reissue Notice of Funding Opportunity (NOFO) to solicit applications for innovative, interactive research to answer significant scientific questions that are important for the mission of NINDS, via a synergistic collaboration between outstanding scientists who might not otherwise collaborate. The program project grant is designed to support research in which the funding of several interdependent highly meritorious projects as a group offers significant scientific advantages over support of these same projects as individual research grants.. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in April 2024 with an expected application due dates in May and September 2024. NINDS will not have any receipt dates after September 2024, thus ending the program. This NOFO will utilize the P01 activity code. Details of the planned NOFO are provided below.

This funding opportunity supports U.S.-based organizations in implementing and sustaining effective strategies to prevent substance misuse and use disorders, particularly targeting individuals at risk but not yet diagnosed with a substance use disorder.