Grants for Special district governments - Health

Synopsis: NOFO # DD24-0051 solicits non-research, cooperative agreement applications to conduct population-based surveillance of congenital heart defects (CHD) to describe health outcomes including health equity, with the goal of identifying opportunities to improve the health of all people living with CHD. This project will involve a required component (A) and an optional component (B). The population included in this surveillance activity can be an entire state or a region within a state. Individuals with CHD should be identified through existing data sources including the jurisdiction birth defects surveillance system, electronic health records, administrative data (e.g., Medicaid/Medicare, hospital discharge), or other sources available to funding recipients. Background: Congenital heart defects (CHD) affect about 1% of all births in the United States, and are a leading cause of birth defect-associated infant mortality, morbidity, and healthcare costs. Improvements in early detection and treatment of CHD and consequently in survival have resulted in many people, including those affected by a severe CHD, living into adolescence and adulthood. An estimated two million persons in the U.S. are living with a CHD, including over one million adults; about 12% of these affected adults have a severe CHD. Most current efforts to conduct population-based surveillance of CHD have focused on monitoring newborns. However, little data exist on the descriptive epidemiology of CHD beyond early childhood in the U.S. Despite the public health burden, the lack of population-based surveillance precludes reliable data on people with CHD, their survival, healthcare utilization, and characteristics associated with long-term outcomes. Through this surveillance activity, these data will be assessed, enabling and informing efforts to improve the health and well-being of people with CHD. Objectives: Component A objectives include: (1) assess survival, comorbidities, healthcare utilization during the period 2021-2023, and characteristics associated with long-term outcomes among people with CHD; (2) assess health equity among people with CHD; (3) examine state and national healthcare policies that have an impact on people with CHD; (4) examine COVID-19 and related data such as health care utilization during the pandemic among people with CHD; and (5) work with local/state partners to use site-specific CHD data. Component B objectives include: (1) develop and refine a machine learning algorithm for the surveillance data collected through Component A; and (2) apply this machine learning algorithm to data collected from all recipients funded through Component A.

This funding opportunity supports experienced researchers looking to expand their expertise or shift their career focus through advanced training and research experiences at various institutions.

This funding opportunity supports innovative research into the biological mechanisms behind complex brain disorders, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

This funding opportunity provides financial support to organizations working to reduce lead exposure among children in high-risk communities in Washington, D.C., particularly targeting vulnerable populations such as racial and ethnic minorities, immigrants, and low-income residents.

This funding opportunity supports a wide range of organizations in developing innovative drug therapies for Alzheimer's disease and related dementias, focusing on non-traditional treatment targets and requiring collaboration with NIH throughout the clinical trial process.

This funding opportunity supports innovative research into new risk factors for liver cancer, particularly focusing on non-viral causes and their interactions with established risks, aimed at improving prevention strategies in the U.S. population.

This funding opportunity provides financial support for researchers and organizations to investigate the factors driving tuberculosis transmission and develop innovative methods for prevention and detection in high-burden areas.

This grant provides funding to organizations in Maine, New Hampshire, New York, and Vermont to train and place behavioral health professionals in rural areas facing a shortage of providers.

This funding opportunity supports initiatives that plan to improve health equity and reduce health disparities for women and girls of reproductive age from racial and ethnic minority and underserved communities by integrating comprehensive healthcare services.

This funding opportunity provides financial support for U.S.-based researchers and institutions to develop innovative human models that simulate radiation injuries, aiming to improve understanding and treatment of radiation exposure effects.

The Silvio O. Conte Digestive Diseases Research Core Centers grant, provided by the NIDDK, supports collaborative research on digestive and liver diseases by offering shared resources to enhance productivity and foster new ideas, centered around a theme within the NIDDK's mission.

This funding opportunity supports collaborative research projects in neurology, encouraging diverse teams to tackle significant scientific questions that advance the field through interdependent studies.

The Rural Health Network Development Planning Program supports the planning and development of rural integrated health care networks with specific focus on collaboration of entities to establish or improve local capacity and care coordination in underserved communities. Specifically, the program uses the concept of developing networks as a strategy for linking rural health care network participants together to achieve greater collective capacity to overcome local challenges, expand access and improve the quality of care in the rural communities these organizations serve. The program helps network participants work together on three legislative aims: Achieve efficiencies. Expand access to, coordinate, and improve the quality of basic health care services and associated health outcomes. Strengthen the rural health care system as a whole. The intent is that rural health networks will do the following: Expand access to care. Increase the use of health information technology. Explore alternative health care delivery models. Continue to achieve quality health care across the continuum of care.

This funding opportunity supports the development of diverse cancer research cohorts to improve understanding of cancer causes and outcomes, particularly among underrepresented populations.

This funding opportunity provides support for high-risk clinical trials focused on infectious, immunologic, and allergic diseases, encouraging innovative research that can lead to new treatments and therapies.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA ().

This funding opportunity supports research projects aimed at reducing stigma related to HIV/AIDS in low- and middle-income countries, with a focus on improving health outcomes for affected populations.

This funding opportunity provides financial support for researchers to conduct early-phase clinical trials aimed at developing new treatments or diagnostic tools for heart, lung, blood, and sleep disorders in both adults and children.

This funding opportunity provides financial support to institutions and organizations for creating a centralized data hub and coordinating center that will enhance innovative research methodologies in biomedical science, focusing on alternatives to traditional animal models.

Addressing the Impact of Syndemics on the Health of People with HIV and Diseases and Conditions within the Missions of NIDDK and NHLBI (R01 Clinical Trial Optional)