Grants for Nonprofits - Science and Technology
Explore 3,186 grant opportunities
Application Deadline
Sep 30, 2024
Date Added
Mar 4, 2024
The RHIG Program, established by the Kansas Legislature through House Bill 2208 on May 6, 2021, is designed to strengthen and enhance healthcare services in eligible Kansas counties by providing transitional assistance to hospitals. Funded with $10,000,000 from the American Rescue Plan Act (ARPA) of 2021, the program aims to help hospitals transition their current healthcare delivery models to ones more suitable for their communities. Eligible projects include transitioning to new provider types, service and delivery modifications, market studies, technological advancements such as telemedicine, and personnel acquisition. The program underscores a public-private partnership model requiring a $2 match from private stakeholders for every $1 of state funds. All RHIG funds must be obligated by December 31, 2024, with the program set to expire on June 30, 2025. All counties in Kansas can apply except Douglas, Johnson, Sedgwick, Shawnee, or Wyandotte counties.
Application Deadline
Sep 19, 2024
Date Added
Sep 10, 2024
The mission of the Arizona Department of Health Services (ADHS) Arizona Biomedical Research Centre (ABRC) is to identify and support innovative biomedical research to improve the health of all Arizonans. ABRC is focused on leveraging existing resources, maximizing partnerships, cultivating communication, and promoting innovation. ABRC manages multiple initiatives which are guided by input from leaders and professionals from Arizona’s universities, nonprofit research institutions, hospitals, medical centers, and patient advocacy groups. Financial Notes: Funding Source: The funding source for this Grant is the Health Research Fund (Tobacco Tax) as established by Arizona Revised Statute (ARS) §36-275 (https://www.azleg.gov/ars/36/00275.htm) and §36-773 (https://www.azleg.gov/ars/36/00773.htm). Up to $3,500,000 per year is available for Arizona Investigator Grant (AZ IG) and New Investigator Award (NIA) applications. The maximum award for AZ IG Applications is $225,000.00 annually with a maximum project duration of three (3) years from the award date. The maximum award for NIA Applications is $75,000.00 annually with a maximum project duration of three (3) years from the award date.
Application Deadline
Not specified
Date Added
Oct 9, 2024
This funding opportunity provides financial support to California non-profits and Native American tribes for projects aimed at improving community air quality through education, technical training, and targeted emission reduction strategies.
Application Deadline
Aug 22, 2024
Date Added
Jul 9, 2024
The Catalyst Endowment Fund, managed by the Hartford Foundation for Public Giving, is offering a competitive funding opportunity centered on "Empowering Future Leaders and Community Builders through Youth Sports in Greater Hartford." This initiative aligns with the foundation's broader mission to foster well-being and development within the community. The program aims to leverage the positive effects of youth sports, such as developing teamwork, leadership, and promoting physical and mental health, to create resilient, confident, and empowered individuals. The fund's focus on bridging access gaps to youth sports directly supports the foundation's strategic priority of creating sustainable support systems for the region's youth. The primary beneficiaries of this grant program are youth in Greater Hartford, particularly those in underserved communities who face barriers to accessing sports programs. The overarching impact goal is to empower these young individuals, transforming them into future leaders and community builders. By focusing on sustainable support systems, the program seeks to create lasting positive change beyond the grant duration, addressing systemic inequalities in access to enriching activities. This aligns with a theory of change that posits that providing equitable opportunities in youth sports will lead to enhanced individual development and stronger, more engaged communities. The program's priorities and focus areas are clearly defined to achieve these goals. Infrastructure Development aims to improve existing sports facilities and equipment, ensuring long-term accessibility. Training and Capacity Building initiatives will equip coaches, volunteers, and staff with the skills to deliver high-quality programs, fostering a robust support network. Partnerships and Collaborations are encouraged to strengthen relationships with schools, community organizations, and local businesses, pooling resources and support. Finally, Health and Wellness Integration seeks to embed physical and mental health services within youth sports, promoting holistic well-being and sustained participation. Expected outcomes and measurable results include improved accessibility to youth sports in underserved communities, an increased number of trained coaches and volunteers, stronger community partnerships supporting youth sports, and enhanced physical and mental well-being among participants. The program anticipates fostering increased participation in youth sports, leading to the development of critical life skills such as leadership, teamwork, and resilience. Ultimately, the Hartford Foundation for Public Giving expects these initiatives to contribute to a more equitable and vibrant Greater Hartford, producing a generation of empowered individuals who are prepared to lead and build their communities. The fund has $69,000 available to award, with one or more grants totaling this amount, contingent on the project's size, funding need, and the quality of the proposals submitted in response to the forthcoming Request for Proposal.
Application Deadline
Sep 10, 2025
Date Added
May 27, 2025
This funding opportunity supports innovative research projects aimed at making significant advancements in breast cancer prevention, diagnosis, and treatment, involving collaboration with breast cancer survivors as advocates.
Application Deadline
Not specified
Date Added
Nov 14, 2024
This funding opportunity provides up to $5,000 for neighborhood groups in Montgomery County to implement projects that enhance community pride and improve quality of life through collaboration with local government.
Application Deadline
Not specified
Date Added
Oct 5, 2023
The Research Infrastructure in the Social and Behavioral Sciences Program (RISBS) supports projects that create computational tools and data to facilitate basic research in the social and behavioral sciences that can lead to improved health, prosperity and security. Projects should be aimed at creating computational tools and data to enable research by social scientists. Examples include, but are not limited to, data collection or assembly efforts that result in new resources for a community of researchers or software platforms that facilitate data collection efforts by others. RISBS does not support research by PIs except in service of creation of the infrastructure. Innovation is especially encouraged. RISBS directly supports three key longitudinal surveys and panel studies that provide researchers with data on how American society functions and changes over time (and in 2010 were recognized as among the 60 most significant "discoveries or advances that... have had a large impact or influence on every Americans life... call[ed] the Sensational 60, in honor of NSFs 60th anniversary): The American National Election Study, which started in 1948 and has been funded by NSF since 1977, provides gold standard data on voting, public opinion, and political participation in U.S. national elections. The General Social Survey, a nationally representative interview survey of the U.S. adult population, collects data on a wide range of topics and has been funded by NSF since its inception in 1972. The Panel Study of Income Dynamics, a longitudinal survey of a nationally representative sample of U.S. families begun in 1968 (with NSF taking over most of its funding in 1980) collects data on a wide array of economic, social and health factors. The RISBS program administers separate solicitations for the American National Election Study (ANES), the General Social Survey (GSS) and the Panel Study of Income Dynamics (PSID). These solicitations have specific requirements and submission deadlines. Other infrastructure proposals may be submitted directly to the RISBS program at any time or transferred from other SBE programs following the respective programs submission guidelines. RISBS also collaborates with other programs in the social and behavioral sciences through a co-funding process to support projects that create especially valuable tools for researchers in those fields or are furthering innovations in research infrastructure. Prospective PIs may also be interested in the Human Networks and Data Science Program Infrastructure(HNDS-I), which supports proposals addressing the development of data resources and relevant analytic techniques that support research in the social, behavioral and economic sciences.Prospective PIs are strongly encouraged to contact the RISBS program officers and/or program officers from other SBE programs that may be applicable to the proposal before submitting to RISBS and to refer to the NSF Proposal Award Policies Procedures Guide (PAPPG) policies on duplicate or substantially similar proposals.
Application Deadline
Sep 20, 2024
Date Added
Jun 24, 2024
Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).
Application Deadline
Jun 30, 2024
Date Added
Apr 15, 2024
The Sensata Foundation, established in 2017 as the philanthropic arm of Sensata Technologies, is a 501(c)(3) organization dedicated to strengthening local communities. Its mission aligns with Sensata's sustainability priorities, focusing on community development and STEM education. The Foundation provides grants for specific programs and projects rather than general operating support, prioritizing agencies that serve communities where Sensata employees live and work in the U.S. The Foundation's strategic priorities are centered around two key focus areas: STEM Education and Community Support. In STEM Education, the Foundation aims to ensure equitable access to science, technology, engineering, and mathematics for all youth in grades K-12, particularly those from underserved communities, including racial and ethnic minority groups, students with disabilities, and girls. The goal is to empower critical thinking and problem-solving skills, and to inspire future leaders by providing additional learning avenues like mentorships to further educational growth in STEM. Under Community Support, the Foundation addresses prevailing needs within local communities. Key focus areas include combating food insecurity through support for food banks and distribution centers, assisting individuals experiencing homelessness with shelter and transition services, promoting social and economic mobility to enhance personal stability and quality of life, and supporting environmental programs that create clean and green outdoor spaces for community enjoyment. The expected outcomes and measurable results from these grants involve direct support for qualifying charitable entities, leading to strengthened local communities and advancements in the Foundation's sustainability priorities. While specific metrics are not detailed, the focus on specific programs/projects suggests that the impact will be seen in the successful implementation and outcomes within the two focus areas. The grants typically range from $5,000 to $25,000, are usually one-year awards, and are given to active 501(c)(3) non-profit organizations that have a presence or service area where Sensata Technologies has facilities or employees, and adhere to a non-discrimination policy.
Application Deadline
Mar 14, 2025
Date Added
Mar 15, 2024
Despite huge advances in the development of novel medical therapies, Americans still live with poor health outcomes and suffer from the ill-effects of disease. Current medical research and the medical delivery system in the United States focus primarily on the reactive treatment of illnesses, despite the fact that many diseases or their ill-effects are preventable.The Proactive Health Office (PHO) at ARPA-H is seeking solutions to improve the healthspan and health outcomes of Americans prior to the onset of disease and/or the development of diminished quality of life from illness. Specifically, PHO hypothesizes that 1) population-level improvements in access to and uptake of disease prevention and wellness-promoting behaviors and 2) development of novel early-detection methods and prophylactic interventions could drastically improve the health of American throughout their lives, and 3) that system level innovations are required for delivery of proactive health effectively. Specific PHO interest areas include:Novel prevention, detection and prophylactic treatment methods for disease: Novel and scalable methods for early detection of disease and illness including the use of low/no-cost sensing modalities. Prophylactic approaches to prevention of diseases and harmful disease outcomes. Methods for continuous and widespread sensing of health state and early disease indicators that can be deployed at population-scale.Population-level approaches to increase the adoption of prevention and wellness behaviors: Early indicators of disease and pre-disease states and measures associated with proactive health outcomes that are both inexpensive and effective. Low-cost, high-uptake mental health resiliency and mindfulness building methods for individuals. Methods to inform and educate individuals about healthy behaviors including lifestyle and preventative medical measures. Methods that incentivize individuals to adopt and maintain healthy behaviors. Novel approaches to increasing individual healthspan and independence even in the absence of disease.System innovation for the delivery of proactive health outcomes: Novel, robust and predictive surrogates for long-term health outcomes with associated epidemiological models. Valuation models for long-term treatment effects for vaccination, screening and other public health interventions. New funding and delivery models for preventative intervention.Other high-quality submissions that propose revolutionary technologies that meet the goals of PHO will be considered even if they do not address the topics listed above.Proposals are expected to use innovative approaches to enable revolutionary advances in medicine and healthcare, and the science and technology underlying these areas. While approaches that are disease agnostic are encouraged, ARPA-H welcomes proposals that bring radically new insights to address specific diseases including, but not limited to, cancer, diabetes, neurological diseases, pediatric and maternal/fetal health, infectious diseases, and cardiovascular disease.Specifically excluded are proposals that represent an evolutionary or incremental advance in the current state of the art or technology that has reached the clinical trial stage. An example of this type of proposal might include the request to fund clinical trials of an otherwise developed product. Additionally, proposals directed towards policy advocacy, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission.
Application Deadline
Sep 6, 2024
Date Added
Aug 9, 2024
The Lake County Community Foundation Fall Grant focuses on two key priority areas: Leadership Development and Animal Welfare. The Foundation's mission is aligned with fostering a stronger nonprofit sector through leadership development opportunities that benefit Lake County's broader nonprofit community, rather than individual organizations. For animal welfare, the Foundation, through the Lake County Humane Society Fund, seeks to cultivate innovative approaches and address unmet needs for animals in Lake County. This grant embodies the Foundation's commitment to strategic investments that strengthen the community. Within Leadership Development, the Foundation prioritizes projects that build a pipeline of competent, emerging leaders for the county's nonprofit sector. A crucial aspect is increasing access to quality programming for leaders of color and other underrepresented groups, ensuring a diverse and inclusive leadership base. The ultimate goal is to equip leaders to better serve their nonprofit organizations, clients, and communities, thereby amplifying their collective impact across Lake County. This approach reflects the Foundation's theory of change, which posits that investing in leadership capacity will lead to more effective and sustainable social impact. For Animal Welfare, the grant targets organizations dedicated to the needs of animals in Lake County. The focus is on innovative approaches to support animal welfare and addressing needs where the applicant is the sole service provider. This area aligns with the Foundation's broader aim of addressing critical community needs and fostering a compassionate environment for all residents, including animals. The expected outcome is improved animal welfare through targeted interventions and support for organizations making a significant difference in this area. The Foundation's strategic pillars of Economic Justice, Community Ownership, and Rapid Community Response guide the evaluation criteria for all applications. Successful proposals will demonstrate alignment with these pillars and respond to high-priority needs identified by current Lake County data. The Foundation also emphasizes diversity and equity within applicant organizations, seeking staff, leadership, and boards that reflect the communities they serve. Furthermore, strong, documented partnerships, the potential to leverage other resources, and a high probability of affecting significant change over the next three years are key considerations, along with cost-effective service delivery and a proven track record of achieving outcomes. These criteria underscore the Foundation's commitment to impactful, sustainable change.
Application Deadline
Dec 9, 2024
Date Added
Jul 18, 2024
This funding opportunity provides financial support for research projects that aim to improve the inclusion, independence, and quality of life for individuals with disabilities, particularly focusing on underserved populations and critical issues affecting these communities.
Application Deadline
Not specified
Date Added
Dec 16, 2024
This funding opportunity supports educational institutions, nonprofits, and government agencies in Hawaiʻi to develop projects that boost local business growth, job creation, and sustainability on the island.
Application Deadline
Jan 16, 2025
Date Added
Sep 11, 2024
This funding opportunity provides financial support for innovative projects that develop and scale up biofuel technologies, particularly for transportation sectors that are hard to electrify, with a focus on reducing greenhouse gas emissions and promoting environmental justice.
Application Deadline
Feb 11, 2025
Date Added
Dec 4, 2024
This funding opportunity provides $5 million to support the deployment and commercialization of innovative technologies in public transportation, aimed at federal, state, local, and tribal governments, as well as public transit providers and educational institutions.
Application Deadline
Jun 6, 2024
Date Added
Apr 5, 2024
The National Aeronautics and Space Administration (NASA) Headquarters has released a solicitation, titled Early Stage Innovations (ESI), as an appendix to the Space Technology Mission Directorate (STMD) umbrella NASA Research Announcement (NRA) titled "Space Technology Research, Development, Demonstration, and Infusion 2024 (SpaceTech REDDI 2024), on April 4, 2024. The ESI solicitation is available by opening the NSPIRES homepage at https://nspires.nasaprs.com/, selecting Open under "Solicitations," and searching "Early Stage Innovations (ESI24)" under Keywords. The Space Technology Research Grants (STRG) Program within STMD seeks proposals from accredited U.S. universities to develop unique, disruptive, or transformational space technologies that have the potential to lead to dramatic improvements at the system level performance, weight, cost, reliability, operational simplicity, or other figures of merit associated with spaceflight hardware or missions. The projected impact at the system level must be substantial and clearly identified. Only accredited U.S. universities are eligible to submit proposals. Teaming is permitted see solicitation for complete eligibility requirements as well as teaming restrictions. A Principal Investigator (see solicitation for restrictions) or Co-Investigator may participate in no more than two proposals in response to this solicitation. NASA encourages submission of ESI proposals on behalf of tenure-track or tenured faculty members at all U.S. universities and especially encourages proposals submitted on behalf of and/or that include as team members women, members of underrepresented minority groups, and persons with disabilities. The solicitation exclusively seeks proposals that are responsive to one of the following two topics: Topic 1 Computational Materials Engineering for Lunar Metals Welding Topic 2 Passive Lunar Dust Control through Advanced Materials and Surface Engineering NASA anticipates addressing other topics in future ESI Appendix releases. The financial and programmatic support for ESI comes from the Space Technology Research Grants Program within the Space Technology Mission Directorate. Awards are planned to start in January 2025. NASA plans to make approximately 6 awards as a result of this ESI solicitation, subject to the receipt of meritorious proposals. The actual number of awards will depend on the quality of the proposals received; NASA reserves the right to make no awards under this solicitation. STMD is strongly committed to ensuring that proposal review is performed in an equitable and fair manner that reduces the impacts of any unconscious biases. To this end, this Appendix will employ a Dual-Anonymous Peer Review (DAPR) process to evaluate proposals. Using DAPR, not only are proposers not told the identities of the reviewers, but the identities of the proposers (personnel and organization names) will not be shared with the reviewers until after the technical review of all anonymized proposals has been completed. All proposals must be submitted electronically through NSPIRES by an authorized organizational representative. Notices of Intent (strongly encouraged) are due by May 9, 2024, with proposals due on or before June 6, 2024, 5 pm Eastern. Detailed submission instructions and due dates are provided in the solicitation. Potential proposers and their proposing organizations are urged to familiarize themselves with the submission system, ensure they are registered in NSPIRES, and submit the required proposal materials well in advance of the deadline. All technical and programmatic comments and questions may be addressed by email to the Space Technology Research Grants Program Executive, at hq-esi-call@mail.nasa.gov. Responses to inquiries will be answered by email and may also be included in the Frequently Asked Questions (FAQ) documents located on the NSPIRES page associated with the solicitation; anonymity of persons/institutions who submit questions will be preserved.
Application Deadline
Oct 1, 2024
Date Added
May 6, 2025
This grant provides financial assistance for transportation to local baseball and hockey games for accredited schools and nonprofit organizations in northwest Ohio and southeast Michigan that demonstrate a need.
Application Deadline
Sep 30, 2024
Date Added
Jul 24, 2024
The Visit BG Ohio 2025 Tourism Grant Program offers financial support ranging from $1,000 to $10,000 for projects, events, and activities that promote tourism, increase overnight stays, and provide economic benefits to the City of Bowling Green, with a focus on capital improvement, sports, conferences, festivals, large events, and arts and culture.
Application Deadline
Not specified
Date Added
May 20, 2024
The Pennsylvania HOME-American Rescue Plan Supportive Services (HOME-ARP SS) funds can provide a broad range of supportive services to individuals and families that meet one of the qualifying populations as defined in Notice CPD-21-10: Requirements for the Use of Funds in the HOME-American Rescue Plan Program. Supportive services may be provided to individuals and families who are not already receiving the services outlined in the Notice through another program. Applicants may establish a separate supportive services activity or activities or may combine supportive services with other HOME-ARP activities. Notice CPD-21-10: Requirements for the Use of Funds in the HOME-American Rescue Plan Program HOME-ARP funding is provided by the U.S. Department of Housing and Urban Development (HUD) and administered by DCED. Financial Info: The minimum funding request for Supportive Services projects is $25,000. Up to 5% may be requested for administrative costs.
Application Deadline
Mar 14, 2025
Date Added
Mar 15, 2024
This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change.Considering the current healthcare challenges that we face today, the goal of achieving better health outcomes is a moving target that requires daring and adaptable solutions. HSF awardees will develop innovative technologies, tools, and platforms that can be applied to a broad range of diseases. The following interest areas define the ground-breaking research we seek to support:Breakthrough Technologies: Paradigm shifting technologies that will change how we approach the diagnosis, treatment, and impact of diseases and conditions. Novel approaches to improve maternal and fetal medicine, decrease maternal morbidity and mortality during birth, and the post-partum period. Efforts should include new technology to monitor, detect, and/or treat maternal and/or fetal complications with less invasive and traumatic methods. Foundational advances in genetic, epigenetic, cellular, tissue, and organ replacement therapies that enable personalized medical interventions at scale in a manner that is accessible, cost-effective, and designed to impact the communities of greatest need. Interventions that target and reverse disease pathogenesis and/or enhance plasticity to address diseases of the nervous, neuromuscular, skeletal, lymphatic, cardiovascular, and other organ systems. Novel approaches to diagnose and treat diseases of the lymphatic system, particularly rare diseases, with a focus on the effects of genetic expression in the lymphatic system and/or models demonstrating the relationship between lymphatic dysfunction and health and disease.Transformative Tools: Novel, agile solutions that will move from bench to bedside quickly, facilitating revolutionary advances in medical care. Development of tools that counter idiosyncratic, off-target, or chronic effects of medicines that are commonly used or that are being used experimentally to treat or prevent disease. Development of bionics to restore sight, hearing, taste, or smell. Site-selective neuromodulation to regulate specific physiological functions and treat chronic health conditions such as inflammation, pain, and metabolic or endocrine disorders. Synthetic biology approaches to diagnosing, treating, and/or curing a multitude of diseases. Novel physics and/or chemistry-based approaches to improve imaging that reduces cost, increases availability, expands capability, improves resolution, reduces exposure to radiation, and accommodates pediatric patient populations. Integrated sensing and delivery devices for treating and diagnosing chronic health conditions, including mental health conditions or substance use disorders. Miniaturization of complex hardware to enable broader access to pediatric and other patient populations, as well as portability, such as diagnostic, treatment, imaging, or other devices.Platform Systems: Adaptable, multi-application systems and technologies that are reconfigurable for a wide variety of clinical needs Novel molecular platform approaches, including the modulation of host systems, delivery to targets with spatial and temporal precision, and mitigation of off-target effects to accelerate interventions that dramatically improve health outcomes. New approaches to accelerate and routinize mammalian and microbial cellular engineering to enable next generation therapeutic applications, develop multiscale interventions, and automate hypothesis generation and discovery to expand those applications to disease states in which cellular therapies have not traditionally been employed. Innovative approaches at the intersection of artificial intelligence, high performance computing (including quantum computing) and biological systems, including enabling de novo design of biomolecules with entirely new phenotypes.Other high-quality submissions that propose revolutionary technologies that meet the goals of HSF will be considered even if they do not address the topics listed above.Proposals are expected to use innovative approaches to enable revolutionary advances in medicine and healthcare, and the science and technology underlying these areas. While approaches that are disease agnostic are encouraged, ARPA-H welcomes proposals that bring radically new insights to address specific diseases including, but not limited to, cancer, diabetes, neurological diseases, pediatric and maternal/fetal health, infectious diseases, and cardiovascular disease.Specifically excluded are proposals that represent an evolutionary or incremental advance in the current state of the art or technology that has reached the clinical trial stage. An example of this type of proposal might include the request to fund clinical trials of an otherwise developed product. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission.

