Grants for Nonprofits - Science and Technology

The FY24 PCRP Early Investigator Research Award supports prostate cancer-focused research opportunities for individuals in the early stages of their careers under the guidance of one or more designated mentors. This opportunity allows early-career investigators to develop a research project, investigate a problem or question in prostate cancer research, and further their intellectual development as prostate cancer researchers of the future. All application components for the FY24 PCRP Early Investigator Research Award are to be written by the Principal Investigator (PI), with appropriate direction from the mentor(s).Key elements of this award mechanism are as follows: Principal Investigator: The postdoctoral investigator is considered the PI of the application and must exhibit strong potential for and commitment to pursuing a career as an investigator at the forefront of prostate cancer research; however, the PI is not required to have previous prostate cancer research experience. The PI must have 3 years or less of postdoctoral research experience (excluding clinical residency or clinical fellowship training) as of March 31, 2025. The PCRP strongly encourages applications from PIs who demonstrate a commitment to pursuing a career focused on prostate cancer health disparity research. Mentor(s): Applications must include at least one mentor appropriate to the proposed research project who has experience in prostate cancer research and mentoring as demonstrated by a record of active funding, recent publications, and successful mentorship. The primary mentor can be a junior faculty member, in which case the PI is encouraged to include a secondary mentor with a more robust track record in prostate cancer research and mentorship. Applications that focus on prostate cancer health disparity should include at least one mentor with experience in prostate cancer health disparity research. The selected mentor(s) should also demonstrate a clear commitment to the development of the PI toward independence as a prostate cancer researcher. Research Approach: Proposed research ideas are required to address one or more of the FY24 PCRP Overarching Challenges. Projects that specifically address the FY24 PCRP Overarching Challenge to advance health equity and reduce disparities in prostate cancer are strongly encouraged. The scientific rationale and experimental methodology should demonstrate in-depth analysis of the research problem presented. The feasibility of the research design and methods should be well defined, and a clear plan should be articulated as to how the proposed goals of the project can be achieved. Inclusion of preliminary data relevant to prostate cancer and the proposed project is encouraged but not required. Any preliminary data provided should be from the PI, mentor(s), or member(s) of the collaborating team. Additionally, required resources should be identified and supported through documentation. Research involving human subjects and human anatomical substances is permitted; however, clinical trials are not allowed under this funding opportunity. Researcher Development Plan: The PI must outline an individualized, prostate cancer-focused researcher development plan, which should include a clearly articulated strategy for acquiring the necessary skills, competence, and expertise that will enable the PI to successfully complete the proposed research project and foster the PIs development as an independent prostate cancer researcher. An environment appropriate to the proposed mentoring and research project must be clearly described, although any deficiencies of resources and/or mentorship at the PIs institution can be mitigated through collaboration(s) with other institutions. If the PI will be utilizing resources at another institution to successfully complete the proposed project, then the PI is strongly encouraged to designate a co-mentor at the collaborating institution.Investigators are strongly encouraged to incorporate the following components into their study design, where appropriate, in order to maximize the potential impact of the proposed research project: authentication of proposed cell lines; statistical rigor of preclinical animal experiments; and incorporation of experiments to assess clinical relevance and translatability of findings. Studies utilizing data derived from large patient studies that include long-term health records, biospecimen repositories, and pre-existing research and apply state-of-the-art genomic and/or proteomic analysis, bioinformatics, and/or mathematical models to such data are also encouraged. Investigators are highly encouraged to provide a letter of support indicating access to and the availability of any resources required to support the study.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more-effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (http://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Clinical trials are not allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 PCRP Early Investigator Research Award should not exceed $300,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $6.24M to fund approximately 13 Early Investigator Research Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity supports clinical research projects that extend or enhance existing breast cancer studies, requiring collaboration with consumer advocates to improve outcomes for patients and the community.

The 2025 Massachusetts 250 Grant Program, offered by the Executive Office of Economic Development (EOED) through the Massachusetts Office of Travel and Tourism (MOTT), is a competitive grant designed to fund programming and interpretation related to the American Revolution in Massachusetts. The program aims to increase tourism and travel within the state by highlighting its pivotal role in the nation's founding. This aligns with a broader mission to promote Massachusetts' historical significance and attract visitors, thereby bolstering the state's economic development through tourism. The grant targets municipalities, public agencies, tribal entities, and nonprofit organizations (501(c)3, 501(c)5, or 501(c)6) operating in Massachusetts. Eligible projects must demonstrate a direct connection to the American Revolution, link to themes of revolution and independence, celebrate significant historical "firsts" in Massachusetts, or offer creative approaches to commemorating the nation’s semiquincentennial. The program emphasizes that grant funds can be utilized for both programming and marketing initiatives. The primary priorities and focus areas for this grant include fostering a deeper understanding of the American Revolution's impact in Massachusetts and enhancing the state's appeal as a historical destination. The grant's strategic priorities are centered on supporting projects that interpret and tell these stories effectively, ultimately driving increased tourism. This implicitly supports a theory of change where investments in historical programming and marketing lead to greater engagement, visitor numbers, and economic benefits for the state. Expected outcomes and measurable results include an increase in tourism and travel to and within Massachusetts, successful programming that engages visitors with the American Revolution, and effective marketing campaigns that raise awareness of Massachusetts' historical significance. While specific quantitative metrics are not detailed, the competitive nature of the grant and the emphasis on increasing tourism suggest that successful applicants will demonstrate a clear plan for achieving these outcomes and, presumably, for measuring their impact. The program anticipates awarding up to $1,500,000 in FY25, with individual grants ranging from $5,000 to $100,000. This substantial funding demonstrates the state's commitment to commemorating the American Revolution and leveraging its historical assets for economic growth. Eligibility also requires compliance with regulations such as the MBTA Communities Act for municipal applicants, good standing with the Commonwealth, and current tax payments, ensuring responsible use of public funds.

This grant provides funding to nonprofit organizations and government entities to support projects that enhance community life in Worth County, Iowa, across various sectors such as arts, education, health, and environment.

The Bowker Foundation awards grants to promote the education, health, welfare, and rehabilitation of young women in Indiana, with emphasis on Fort Wayne and Allen County. The foundation invests in programs that expand opportunities and improve outcomes for young women and girls. Funding is available for initiatives in education, health, and human services that directly support the stated purpose. Average grants range from 5,000 to 30,000 dollars, and total annual giving averages 75,000 dollars. Requests should articulate clear objectives, activities, and expected benefits for the target population. Eligible applicants are 501(c)(3) charitable organizations. Applications must be submitted through the online grant application form or an accessible alternative designed for assistive technology users. Grants should focus on Indiana communities, with priority attention to Fort Wayne and Allen County. Applications are due May 1, 2024. Grant duration is not specified. Additional details are available through the trustee materials referenced by Wells Fargo.

The Noble County Community Foundation, in partnership with the Foundation for Appalachian Ohio, is offering grants to nonprofits, schools, and public organizations for projects and programs that benefit Noble County residents and communities. This initiative aligns with the foundation's mission to advance opportunities within the county by addressing key areas of need, known as the Pillars of Prosperity. The program seeks to empower local efforts and unleash the potential within Noble County. The grant program targets individuals of all ages within Noble County. The core impact goal is to create opportunities, meet pressing needs, and foster the potential of the community. The focus is on supporting a wide range of projects and programs that contribute to the overall well-being and development of the county's residents. Priorities for funding are centered around five critical areas: arts and culture, community and economic development, education, environmental stewardship, and health and human services. The foundation emphasizes supporting efforts that are spearheaded by local individuals and organizations. While funding requests typically range from $500 to $2,500, larger requests may be considered based on their potential for significant impact within these priority areas. Expected outcomes include tangible improvements and advancements across the Pillars of Prosperity. Measurable results will likely be tied to the specific goals of each funded project, demonstrating how they address community needs and create opportunities. The foundation's strategic priorities are deeply rooted in community development and empowerment, with a theory of change that posits by investing in these key areas, the overall quality of life and future prospects for Noble County residents will be significantly enhanced.

This grant provides funding to support research and initiatives that promote diversity, equity, inclusion, and accessibility for individuals with disabilities in STEM fields and education.

This funding opportunity provides financial support for nonprofit organizations in Arizona to distribute free HIV self-test kits to at-risk communities, aiming to improve access to testing and reduce barriers related to HIV.

This funding opportunity is designed to support organizations in Beltrami County that provide housing solutions, including construction, rehabilitation, and supportive services, to improve the availability and affordability of safe housing for low to moderate-income families and individuals.

The United Way of Southern Kentucky is seeking proposals for grants aimed at implementing community impact strategies in the areas of Education, Income, Health, and Safety Net, inviting tax-exempt, nonprofit organizations that align with these strategies to apply before the deadline on 09/30/2024.

The Learning Landscapes Challenge, sponsored by Siegel Family Endowment (SFE) and the Walton Family Foundation (WFF), aims to integrate social, digital, and physical infrastructure to bridge current and future learning paradigms. This initiative aligns with the foundations' broader missions to support changemakers and foster innovative approaches to education. By focusing on infrastructure, the challenge seeks to create more connected and effective learning environments, reflecting a strategic priority to enhance educational ecosystems through systemic improvements. The challenge targets "changemakers," including individuals, groups, or entities with innovative ideas, particularly those operating in the United States, as lead individuals or entities must maintain a primary place of operations there to be eligible for monetary prizes. The impact goal is to achieve tangible, transformative effects in learning, extending beyond single communities. The program prioritizes solutions that incorporate multiple dimensions of infrastructure or utilize infrastructure in novel ways to create scaled impact. The Learning Landscapes Challenge is structured in three phases to identify and support infrastructural concepts. Phase 1 is open to all eligible entrants, with up to 40 winners receiving $5,000 and an invitation to the Phase 2 accelerator. Phase 2 is exclusively for Phase 1 winners, with up to five recipients each receiving $200,000 and an invitation to the Phase 3 incubator. Finally, Phase 3 is for Phase 2 winners, with up to two grand-prize winners each receiving $500,000. These phased awards, totaling up to $2.2 million, are designed to progressively refine and scale solutions. Expected outcomes include the development and implementation of innovative learning solutions that integrate various infrastructures, leading to more accessible and effective learning experiences. Measurable results are tied to the progression through the phases and the successful scaling of these solutions beyond initial communities. The foundations' theory of change suggests that by supporting the development of robust and integrated learning infrastructures, they can catalyze significant improvements in educational access, quality, and adaptability, ultimately preparing learners for future challenges and opportunities.

This funding opportunity supports small pilot projects that enhance understanding of the human virome, inviting collaborations from various organizations, including educational institutions and nonprofits, to develop innovative tools and methods for studying the interactions between viruses and human health.

This funding opportunity supports 501(c)(3) organizations in Manhattan and Riley County, Kansas, to create public humanities projects that foster community engagement and exploration of what it means to be human.

This grant provides funding to nonprofit organizations for projects that enhance health, education, arts, and community development in the Homer area of Michigan, particularly benefiting underserved populations.

The Mid-Career Professional Development Grant, provided by Forecast, offers $5,000 to Minnesota-based artists to fund activities like residencies, conferences, travel, study, and project development, aimed at advancing their public art careers, with the grant period running from January 1, 2025, to November 30, 2025.

This funding opportunity provides financial support for small and mid-sized manufacturers in Illinois to develop internship and workforce training programs that enhance skills and address labor shortages.

This funding opportunity supports research on terrestrial ecosystems, focusing on plant-soil-microbe interactions and the ecological challenges of coastal and degraded lands, aimed at universities, nonprofits, and private organizations in the U.S.

This project seeks to develop and prototype advanced electronic warfare solutions for unmanned platforms, inviting technology vendors to collaborate and innovate in addressing current gaps in electromagnetic spectrum operations.

This grant provides financial support to artists in Franklin County, Ohio, for creating public exterior murals, requiring a secured location and partial funding from a commissioning organization.

This program provides funding to enhance research opportunities and collaborations at Minority-Serving Institutions, aiming to diversify the STEM workforce in the social, behavioral, and economic sciences.