Grants for Public and State controlled institutions of higher education - Science and Technology

Orthopaedic injuries have a profound impact on military readiness and return to work/activity/duty. In the military, extremity battle wounds comprise approximately 50% of injuries reported in the Department of Defense Trauma Registry. Additionally, orthopaedic injuries and conditions that occur outside of combat (e.g., during training, leisure activities, resultant from old injuries) present one of the greatest threats to the readiness of our Service Members and military. Early stabilization, treatment, and rehabilitation of orthopaedic injuries in both civilian and military populations have led to better outcomes, particularly in the prevention of secondary complications and in minimizing morbidity. Availability of orthopaedic care and treatment as early as possible, or as close to the point of injury as possible, also minimizes limb loss and affects military readiness.Although the PRORP is interested in supporting military-focused research, research supported by the PRORP is expected to also apply to all individuals who have sustained a major orthopaedic injury.With the initiation of the Arthritis Research Program, the FY24 PRORP may not fund arthritis research; however, research that addresses conditions or health abnormalities related to arthritis is permitted provided the proposed research addresses the selected Focus Area.The PRORP CTRA is intended to support high-impact and/or emerging clinical research that may not be ready for a full-scale randomized controlled clinical trial. Projects should demonstrate potential to impact the standard of care, both immediate and long-term, as well as contribute to evidence-based guidelines for the evaluation and care of military, Veterans, and all patients with orthopaedic injuries. One goal of the FY24 PRORP CTRA is to translate current and emerging techniques and interventions into the clinical space to better serve military and non-military patients. A holistic approach that takes into account the health, functional abilities, and quality of life of individuals who have sustained an orthopaedic injury should be considered. Another goal is to identify the most effective diagnosis, treatment, rehabilitation, and prevention options available to support critical decision-making for patients, clinicians, other caregivers, and policymakers.The FY24 PRORP CTRA differs from the FY24 PRORP Clinical Trial Award (CTA) in that the CTRA allows for clinical research projects that may or may not include a clinical trial, whereas the CTA is restricted to clinical trials only.Funding from this award mechanism must support clinical research and may not be used for animal research.Clinical research encompasses research with patient samples, data, and interaction with patients that may or may not be considered a clinical trial. Clinical research is observational in nature and includes: (1) Research that does not seek to evaluate the effects of interventions. Research conducted with human subjects (or on material of human origin such as data, tissues, specimens, and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects but does not seek to assess the effects of an intervention, qualifies as clinical research. Patient-oriented research may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies. (2) Epidemiologic and behavioral studies that do not seek to study the safety, effectiveness, and/or efficacy outcomes of an intervention. (3) Outcomes research and health services research that do not fit under the definition of clinical trial. Excluded from the definition of clinical research are in vitro studies that utilize human tissues that cannot be linked to a living individual. Note: Studies that meet the requirements for exemption under 46.104(d)(4) of the Common Rule are not considered clinical research as defined by the CDMRP. Exemption category 4 refers to secondary research for which consent is not required.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document_DEC2022.pdf.Proposed studies submitted to the CTRA may be interventional and may involve some retrospective data analysis. Note that purely retrospective or database-related research is not allowed under this funding opportunity. Small pilot clinical trials with human subjects are allowable.Key aspects of the PRORP CTRA mechanism: Preliminary Data Are Required: Inclusion of preliminary data relevant to the proposed clinical research is required. Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical research appropriate to the objectives of the study. Studies utilizing human biospecimens or datasets that cannot be linked to a specific individual, gender, ethnicity, or race (typically classified as exempt from Institutional Review Board [IRB] review) are exempt from this requirement. Intervention Availability: The application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study. Statistical Analysis and Data Management Plans: The application should include a clearly articulated statistical analysis plan, a power analysis reflecting sample size projections that will answer the objectives of the study, and a data management plan that includes use of an appropriate database to safeguard and maintain the integrity of the data. If proposing a clinical trial that requires oversight by a Regulatory Agency, the trial must use a 21 CFR 11-compliant database and appropriate data standards.For the purposes of this funding opportunity, Regulatory Agency refers to the U.S. Food and Drug Administration (FDA) or any relevant international regulatory agency unless otherwise noted.If the proposed clinical research involves the use of a drug that has not been approved by the relevant Regulatory Agency for the country where the research will be conducted, then submission of an Investigational New Drug (IND) application, or equivalent, that meets all requirements under 21 CFR 312 may be required. It is the responsibility of the applicant to provide evidence from the IRB of record or the relevant Regulatory Agency if an IND, or equivalent, is not required. If an IND, or equivalent, is required, the regulatory application must be submitted to the relevant Regulatory Agency within 12 months of the CTRA award start date. The IND, or equivalent, should be specific for the product and indication to be tested in the proposed clinical trial. For more information on IND applications specifically, the FDA has provided guidance at https://www.fda.gov/drugs/types-applications/investigational-new-drug-ind-application.If the investigational product is a device, then submission of an Investigational Device Exemption (IDE), or equivalent, application that meets all requirements under 21 CFR 812 may be required. It is the responsibility of the applicant to provide evidence if an IDE, or equivalent, is not required. If an IDE, or equivalent, is required, the IDE application, or equivalent, must be submitted to the relevant Regulatory Agency within 12 months of the CTRA award start date. The IDE, or equivalent, should be specific for the device and indication to be tested in the proposed clinical trial.Womens Health: The CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health. Applications proposing research that solely address womens health may also consider the FY24 PRORP WHRA mechanism, Funding Opportunity Number HT942524PRORPWHRA.Use of Department of Defense (DOD) or VA Resources: If the proposed research involves access to DOD or VA resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research. Refer to Section II.D.2.b.ii, Full Application Submission Components, for detailed information.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated total costs budgeted for the entire period of performance for an FY24 PRORP CTRA should not exceed $1.5M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $6.0M to fund approximately four CTRA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The GIVE Washington County Fund Grants, offered by the Washington County Community Foundation in Pennsylvania, is inviting applications from eligible nonprofits, governmental or educational institutions for a flexible grant of up to $10,000, to be used in eight focus areas including animal welfare, arts, community improvement, conservation, education, health, human needs, and religion, excluding general operating or routine program support.

This program provides funding to U.S. colleges and universities to foster collaborative research partnerships with industry and government, focusing on innovative solutions to critical national challenges while developing a skilled workforce in science and engineering.

This funding opportunity provides financial support to organizations working to strengthen export controls and compliance measures against the Chinese Communist Party's efforts to acquire advanced technologies for military and economic purposes.

The Fiscal Year 2025 Air Force Young Investigator Research Program (YIP) intends to support individual early in career scientists and engineers who have received Ph.D. or equivalent degrees by 01 April 2017 or later showing exceptional ability and promise for conducting basic research. The program objective is to foster creative basic research in science and engineering; enhance early career development of outstanding young investigators; and increase opportunities for the young investigator to recognize the Air Force and Space Force mission and related challenges in science and engineering.Individual awards are made to U.S. institutions of higher education, industrial laboratories, for- profit, or non-profit research organizations where the principal investigator (PI) is employed on a full-time basis and holds a regular, non-contractor position. A YIP PI must be a U.S. citizen, national, or permanent resident. Researchers working at a Federally Funded Research and Development Center, or a Department of Defense (DoD) Laboratory are not eligible for this competition.YIP awards are funded up to $150,000 per year for three years, for a total of $450,000. No single year may exceed $150,000. Please review the remainder of this announcement for additional information.Under this competition, an anticipated thirty-seven (37) traditionally funded YIPs and two YIPs funded in partnership with the Laboratory for Physical Sciences (LPS) in the Quantum Information Sciences research discipline may be awarded. There may be potential for an additional 37 YIPs funded from other AFOSR research funding. All actions are based on the availability of funds.

This funding opportunity provides financial support for research consortia focused on improving the diagnosis and treatment of rare diseases through collaborative, patient-centered clinical studies involving multiple institutions and patient advocacy groups.

This funding opportunity provides financial support for research projects that enhance understanding of climate variability in the eastern equatorial Pacific, targeting institutions, non-profits, and governments involved in climate science and modeling.

This grant provides funding to support the development of emerging climate scientists and innovators from diverse backgrounds at research institutions, focusing on professional growth and community engagement to address climate change challenges.

This grant provides funding for innovative cancer research projects that address the unique health needs of military personnel, veterans, and their families, focusing on specific cancer types and strategic goals related to prevention, diagnosis, treatment, and survivorship.

This funding opportunity supports a wide range of research in Earth and space sciences, inviting universities, non-profits, private companies, and international entities to advance scientific knowledge and technology development aligned with NASA's strategic goals.

This grant enables U.S. and UK researchers to collaborate on engineering and physical sciences projects by submitting a single proposal for joint funding and review, streamlining international research efforts.

This funding opportunity provides financial support to organizations working to strengthen global efforts against sanctions evasion by China and Russia, focusing on enhancing compliance systems and technical training for public and private sectors.

This grant provides funding to support the development and enhancement of research infrastructure in computer and information science, specifically aimed at fostering diverse research communities across various educational and non-profit organizations.

This funding opportunity provides financial support to rural libraries in Oregon to create community-focused humanities events that explore themes related to public life and community engagement.

The General Operating Support (GOS) Grants, offered by the Illinois Arts Council Agency (IACA), aim to bolster established not-for-profit organizations that deliver arts programming to their communities. This initiative directly aligns with the IACA's mission to support and strengthen the arts in Illinois. The grant provides financial assistance ranging from $1,000 to $10,000 for activities occurring between November 1, 2024, and August 31, 2025. Eligible entities include registered 501(c)(3) not-for-profit organizations, branches of government, charitable trusts, institutions of higher education, religious organizations, and school affiliate organizations, all of whom must be in good standing with the state and meet specific operational and application criteria. The primary beneficiaries of this grant are not-for-profit arts organizations and, by extension, the diverse communities they serve across all counties in Illinois. The IACA's strategic priorities for this initiative are deeply rooted in equity and outreach. The program specifically focuses on under-resourced communities, including rural areas, high-poverty regions, BIPOC (Black, Indigenous, and People of Color) groups, and individuals with disabilities. This targeted approach seeks to ensure that state support reaches a broader and more equitable demographic of Illinois communities. The initiative's core aims include analyzing the demographic distribution of past awards, engaging constituents for feedback on their needs and experiences, identifying areas for improvement in the IACA's funding approach regarding equity, and recommending actionable steps to achieve greater grant-making equity. These objectives are designed to build an evidence base that can be used to advocate for the resources necessary to expand state support to a wider array of Illinois communities. Expected outcomes and measurable results revolve around a more equitable distribution of arts funding and increased access to arts programming for under-resourced communities. The IACA anticipates that by addressing equity strengths and weaknesses and implementing recommended actions, they will successfully reach more diverse communities. Allowable expenses cover a wide range of operational costs, from artist fees and salaries to facilities, supplies, technology, marketing, and general administrative overhead, ensuring that organizations can effectively implement their programs and achieve their community impact goals.

This funding opportunity provides financial support for research and development of innovative rehabilitation technologies aimed at improving the independence and quality of life for children with orthopedic disabilities.

This funding opportunity provides financial support to organizations working to prevent Russia from acquiring and using chemical and biological weapons through enhanced security measures, training, and international collaboration.

This funding opportunity supports collaborative research between U.S. and Danish organizations to develop innovative mooring and anchoring technologies for floating offshore wind energy, with a focus on reducing costs and improving performance while engaging minority-serving institutions and considering environmental impacts.

This Broad Agency Announcement (BAA) for the Foundational Science Research Unit (FSRU) of the U.S. Army Research Institute for the Behavioral and Social Sciences (ARI) solicits new proposals for its fiscal year 2025 program of basic research in behavioral science. It is issued under the provisions of paragraph 6.102(d) (2) and 35.016 of the Federal Acquisition Regulation (FAR), which provides for the acquisition of basic and applied research and that part of development not related to the development of a specific system or hardware procurement through the competitive selection of proposals and 10 U.S.C. 4001, 10 U.S.C. 4021, and 10 U.S.C. 4022.To meet the operational objectives of the U.S. Army over the next two decades, the Army must improve its capability to acquire, develop, employ, and retain Soldiers and leaders who can individually and as part of a group: Prepare for and adapt quickly to dynamic missions, unpredictable operational environments, and a wide spectrum of contexts; Effectively function autonomously and as part of larger systems in complex, information-rich environments; Perform in extended, hybrid, and continuous operations; Interact and collaborate effectively in joint-service and multi-national operations.ARI requests proposals to conduct basic research that will provide a scientific foundation to support these broad capabilities.The Basic Research program focuses on three strategic areas for advancing personnel science.1. Science of Measurement of Individuals and Collectives: Advanced psychometric theory for deriving valid measurements from complex assessments and continuous streams of data2. Understanding Multilevel and Organizational Dynamics: Multilevel theory and methods for understanding dynamic restructuring, coordination, and composition processes in teams and complex organizations3. Formal/Informal Learning and Development: Holistic models of individual and collective learning and development across work settings and contexts throughout the career spanTo be eligible for an award under this announcement, a potential awardee must meet certain minimum standards pertaining to financial resources and responsibility, ability to comply with the performance schedule, past performance, integrity, experience, technical capabilities, operational controls, and facilities. In accordance with Federal statutes, regulations, and Department of Defense and Army policies, no person on grounds of race, color, age, sex, national origin, or disability shall be excluded from participation in, be denied the benefits of, or be subjected to discrimination under any program or activity receiving financial assistance from the Army.Response Dates (Submissions):White Paper submissions must be received by: 5:00 PM/1700 Eastern Standard Time (EST) on 1 March 2024Proposal submissions must be received by: 5:00 PM/1700 Eastern Daylight Time (EDT) on 1 July 20242024 Response Dates (Questions):Questions regarding White Papers must be submitted in writing to meghan.i.huntoon.civ@army.mil by: 5:00 PM/1700 Eastern Standard Time (EST) on 14 February 2024Questions regarding Proposals must be submitted in writing to meghan.i.huntoon.civ@army.mil by: 5:00 PM/1700 Eastern Daylight Time (EDT) on 15 June 2024

This grant provides funding for U.S. institutions to develop and enhance advanced computing resources that support scientific and engineering research, particularly for underserved communities.