Grants for Public housing authorities - Science and Technology

This funding opportunity supports multidisciplinary research centers focused on understanding and improving the transmission of seasonal influenza viruses, inviting applications from a wide range of organizations, including universities, nonprofits, and government entities.

This funding opportunity provides financial support for pilot studies that develop and test innovative interventions aimed at preventing HIV in populations significantly affected by alcohol use, such as men who have sex with men, sex workers, and individuals recently released from incarceration.

This funding opportunity provides financial support for research and evaluation projects aimed at improving policing practices, enhancing community relations, and ensuring evidence-based policymaking, targeting a wide range of eligible applicants including government entities, educational institutions, and nonprofit organizations.

The objective of this research proposal is to develop physiologically based pharmacokinetic (PBPK) model-based mechanistic in vitro in vivo correlations (IVIVCs) for two major types of long acting injectables (LAIs) such as crystalline suspensions and polymer-based implants by considering their distinct characteristics. The goal of the project is to develop a bottom-up mechanistic PBPK model for these two LAI categories by accounting for the influence of critical formulation attributes of each LAI drug product type to predict its in vivo release mechanism. The model formulation parameters and relevant physiology should be informed with suitable in vitro and in vivo experiments. A suitable preclinical animal model can be used to validate the PBPK model based IVIVCs for both LAI suspensions and polymer based implants. The use of PBPK modelling provides a unique opportunity to understand how the physicochemical properties of drug molecules/polymer, implant specific properties, critical formulation attributes, and physiology, among other things, influence the in vivo release mechanisms of LAI drug products and their disposition characteristics. Moreover, once developed, a mechanistic PBPK model can help to define the 'safe space' for critical formulation attributes relevant to the reference listed drug (RLD) product, explain sources of PK variability and extrapolate predictions to human subjects by leveraging animal model data and by accounting for species-specific physiological differences.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to develop systemic drug delivery platforms for medical countermeasures (MCMs). The Hermes program is explicitly seeking transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity. Successful proposals will include a detailed description of the proposed delivery platform including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor immunogenicity/toxicity, and 4) chosen therapeutic cargo and justification. Systemic delivery platforms developed under the Hermes effort will be transferred to U.S. Government stakeholders for further development.

This funding opportunity supports researchers in developing innovative small animal and human cellular models to study the complex interactions between the central nervous system and the immune system in individuals living with HIV who are on antiretroviral therapy.

This grant provides funding for research institutions to conduct large-scale studies that improve understanding of dental, oral, and craniofacial health through the validation of biomarkers and epidemiological data.

With this solicitation, NIJ seeks to fund proposals for rigorous research and evaluation projects examining the impact of court and other criminal justice tools, practices, and policies on the administration of justice and public safety in state, local, and tribal jurisdictions. In FY2024, the solicitation is focused on four research priorities and their impact on charging, case flow, outcomes, and other prosecution functions: 1) advance prosecution practice and resource management; 2) promote fair prosecution and impartial administration of justice; 3) build prosecution data resources, research capacity, and transparency; and 4) enhance the prosecution workforce and court workgroup.

With this solicitation, NIJ seeks proposals for rigorous research and evaluation projects that inform policy and practice in the field of youth justice and delinquency prevention. Specifically, this solicitation seeks proposals for studies that advance knowledge and understanding in the following two categories: 1. Youth Justice Reinvestment Studies which evaluate the effectiveness, including cost-effectiveness, of youth justice system reforms and subsequent reinvestments into programs that serve youth in their communities. 2. Prevention and Intervention Program Effectiveness Studies which evaluate the effectiveness of school and community-based prevention and intervention programs.

This funding opportunity provides financial support for research and evaluation projects that explore the impact of forensic science on the criminal justice system, targeting a wide range of eligible applicants including government agencies, educational institutions, and nonprofit organizations.

This funding program provides financial support to public and private water providers, municipalities, and nonprofit organizations for projects that develop alternative water supplies and implement water conservation technologies in South Florida.

This funding opportunity supports the development of innovative diagnostic tools for rare genetic disorders by establishing a center that will create standards and a comprehensive dataset to improve the accuracy and speed of diagnoses.

This funding opportunity supports innovative research projects that explore new methods for identifying genetic causes of rare disorders, inviting a diverse range of applicants including governments, nonprofits, and businesses.

This funding opportunity provides financial support to a wide range of organizations to establish a central hub for coordinating research efforts aimed at improving the understanding and treatment of inflammatory bowel disease through data integration and collaboration.

This grant provides funding to research institutions and organizations to study gastrointestinal disorders related to the body's ability to sense internal signals, with the goal of improving understanding and treatment options for these conditions.

This funding opportunity provides up to $4 million to institutions and organizations for establishing a center that will coordinate and integrate diverse data related to chronic pain and musculoskeletal conditions, enhancing research and treatment strategies in the context of the opioid crisis.

This funding opportunity supports collaborative biomedical research programs focused on infectious and immune-mediated diseases, aimed at a wide range of eligible organizations, including universities and nonprofits, to enhance scientific understanding and public health outcomes.

This grant provides funding for a collaborative research initiative aimed at understanding how addictive substances affect specific brain cell populations, encouraging multidisciplinary projects that integrate various data types to create comprehensive profiles of neural behavior in addiction.

This funding opportunity supports nonprofit organizations, public agencies, and federally recognized tribes in New Mexico to enhance community engagement, economic opportunities, and social justice for low-income and disadvantaged individuals.

This funding opportunity supports U.S.-based researchers and organizations in developing advanced 3-D tissue models for drug screening, aiming to improve drug testing and accelerate therapeutic discovery while reducing reliance on animal models.