Grants for Small businesses - Science and Technology

This grant provides funding for early-phase clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction in military personnel and veterans.

The PRMRP Technology/Therapeutic Development Award (TTDA) is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the FY24 PRMRP Topic Areas and one of the FY24 PRMRP Strategic Goals. Products in development should be responsive to the health care needs of military Service Members, Veterans, and their Families. The product(s) to be developed under the PRMRP TTDA mechanism may be a tangible item, such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. (A knowledge product is a non-materiel product that addresses an identified need in a topic area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.)The Technology/Therapeutic Development Award is not intended for basic research. Applicants generating preliminary data, basic research, performing high-risk/high-gain studies should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.

The City of Alhambra in California is offering a Small Business Assistance Grant Program to support local small businesses affected by the COVID-19 pandemic. Eligible businesses must either serve a U.S. Department of Housing and Urban Development (HUD) defined low- and moderate-income area within Alhambra or be owned by low- and moderate-income individuals.Groups of neighbors must find a host organization to sponsor the project and act as the project fiduciary. Applications are accepted year-round until funds are exhausted.

This grant provides funding for researchers, especially early-career scientists and students, to develop and test new technologies for studying solar and space physics through low-cost suborbital flights.

The Regional Site Readiness Program’s Planning Grant, funded by the Illinois Department of Commerce and Economic Opportunity, offers $100,000 to $500,000 to local governments, economic development organizations, nonprofits, for-profit organizations, and private landowners for planning and due diligence activities aimed at preparing industrial and manufacturing sites for future development across all counties in Illinois.

This program provides financial support to established small businesses in downtown North Wilkesboro and Wilkesboro, North Carolina, to enhance their operations through equipment upgrades, physical space improvements, and e-commerce development.

Public Health – Seattle & King County is offering a grant of $100,000 to $500,000 for projects that support diverse youth mental health providers, particularly those connected to LGBTQIA and BIPOC communities, with the aim of increasing access to mental health resources, improving retention, and supporting diverse providers in King County, Washington.

This funding opportunity supports a variety of organizations in developing innovative technologies to identify and target senescent cells, which could lead to new treatments for age-related diseases.

The 80MSFC24M0001 Cooperative Agreement Notice is a grant aimed at fostering partnerships with U.S. industry and academic/non-profit organizations to develop technologies that enhance the commercial space sector, support future NASA missions, and promote the U.S. as a leader in aeronautical and space science, with financial support provided by NASA.

This funding opportunity is designed to support U.S.-based researchers and institutions working on projects that enhance the detection, tracking, and mitigation of potentially hazardous asteroids and comets that could threaten Earth.

This funding opportunity provides $10.6 million for innovative projects that improve floating offshore wind technology, targeting advancements in port infrastructure, transmission systems, and environmental monitoring tools.

This program provides funding to organizations worldwide for innovative projects that use an open-source AI model to address social challenges in areas like economic development and public services.

CDBG COVID-19 Small Business Assistance Grant – Illinois: The City of Danville is offering up to $139,820 in funding through its Community Development Block Grant (CDBG) program, funded by the US Department of Housing and Urban Development (HUD), to support small businesses within the city in addressing the challenges posed by the COVID-19 pandemic. The grant aims to supplement existing federal or state programs and provide targeted assistance to help Danville businesses effectively navigate the impact of the pandemic.

This grant provides funding for innovative research to develop ingestible devices that can sense and stimulate the gut's nervous system to improve stress responses and enhance the performance of military personnel.

Key aspects of the MASA: Principal Investigator: The PI (i.e., Scholar) must be an early-career researcher or physician-scientist no more than 7 years from obtaining their first faculty-level appointment. Postdoctoral fellows (and equivalent) are not eligible for this award mechanism. The PIs record of accomplishments and the proposed research will be evaluated regarding their potential for contributing to the FY24 MRP Focus Area(s) in Section II.A.1. Not all of the PIs accomplishments need to be in the field of melanoma. The PIs organization must demonstrate a commitment to the PI through confirmation of independent laboratory space. Impact: The impact of the proposed research must relate to at least one of the FY24 MRP Focus Areas in Section II.A.1. Impactful research, including basic research, should expedite the advancement of promising ideas towards clinical and/or public utility. The application must articulate the short- and long-term impact the proposed research will have on melanoma research and/or patient care. Career Development: A Career Development and Sustainment Plan (Attachment 7) is required and should be prepared with appropriate guidance from the Career Guide. The Career Development and Sustainment Plan should include a clearly articulated strategy for establishing collaborations and acquiring the necessary skills, competencies, and expertise to advance and sustain an independent career at the forefront of the melanoma field. The Scholar must show milestones and career pathways toward achieving the milestones. The Scholar must articulate commitment to interactions with the MA. Career Guide: The Scholar must designate a Career Guide. The Career Guide must be an experienced melanoma researcher, as demonstrated by a strong record of funding and publications in melanoma. In addition, the Career Guide must demonstrate a commitment to advancing the Scholars career in the melanoma field. The Career Guide must also be committed to fully participating in the MA throughout the award period of performance, including interacting with other MA Scholars and Career Guides and participating in MA activities (e.g., serving on the MA Advisory Board) as requested by MA Leadership. The Career Guide must not be the named Career Guide on any previously funded (FY21-FY23) MASA applications, nor may a Career Guide be named on more than ONE FY24 MASA application. Preliminary Data NOT Required: Preliminary data are not required. However, any unpublished, preliminary data presented should originate from the laboratory of the PI or a member of the research team.

This grant provides funding for researchers to develop and improve preclinical models that better mimic glioblastoma biology, with the goal of enhancing research and treatment outcomes for this aggressive brain cancer.

The Walter F. Goodnough Trust offers grants specifically designed to support the rehabilitation of underprivileged disabled children. The foundation's mission is directly aligned with improving the health and well-being of this vulnerable population through hospitalization within the state of Florida. This grant program is a core component of the trust's philanthropic efforts, focusing on a critical area of need within the healthcare sector for children facing both disability and financial hardship. The primary beneficiaries of this grant program are underprivileged disabled children in Florida who require hospitalization for rehabilitation. The program's impact goal is to facilitate their recovery and improve their quality of life by providing financial support for necessary medical interventions. The trust prioritizes health-related programs and aims to ensure that eligible organizations, specifically 501(c)(3) exempt organizations, can access funding to serve these children. The foundation's strategic priorities are centered on direct impact within Florida's healthcare landscape, particularly for disabled children, and their geographic limitation to Florida underscores this focused approach. While specific detailed expected outcomes and measurable results are not explicitly stated beyond "rehabilitation," the implicit outcome is improved health and functional abilities for the children served. Success would likely be measured by the number of children assisted, the types of rehabilitation services provided, and potentially the duration or effectiveness of their hospitalization and recovery. The average grant size of $2,500 to $5,000, with an average total giving of $15,000 per year, indicates a focus on supporting individual or smaller-scale rehabilitation projects. The foundation's theory of change appears to be that by providing financial grants to qualified organizations, they can directly enable access to crucial rehabilitation services that might otherwise be out of reach for underprivileged families. This strategy emphasizes providing direct financial support for hospitalization and rehabilitation services to address specific community needs within their focused program area of Health.

This funding initiative provides financial support to businesses and organizations along the Route 40 corridor in Cecil County, Maryland, for exterior improvements and revitalization efforts, with a special focus on removing blighted structures.

Funding available through this RFA supports the ongoing research and development of diagnostic tests and devices to treat, detect, diagnose, monitor, and assist in the treatment of cancer. Relevant areas include: Devices and assays for cancer detection, diagnosis, prognosis, monitoring, treatment and prediction of response or resistance to treatment Markers for cancer prevention and control, companion diagnostic to a therapy Development of diagnostic tests to distinguish high-risk early lesions Generally, at the time that an applicant applies to CPRIT pursuant to this RFA, the company has developed a commercial prototype of the device or a pictorial representation of the functional components/elements of the device. With respect to diagnostics, the company has developed assays that work on human samples and whose importance is well justified for development into clinical assays. The applicant should be working toward submitting an Investigational Device Exemption (IDE) or a 510(k) or Premarketing Approval (PMA) and is typically within one year from filing an IDE (or later stage work.) Potential applicants that are not at or near this stage of product development should consider applying for a Texas Seed Company Award. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.

This grant provides financial support to small businesses in New Ulm, particularly in the restaurant, retail, childcare, and light manufacturing sectors, to promote local economic development.