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Grants for Small businesses - Science and Technology

Explore 1,472 grant opportunities

Air Dominance Broad Agency Announcement (BAA)
$750,000,000
U.S. Department of Defense (Munitions Directorate)
Federal

Application Deadline

Not specified

Date Added

Apr 15, 2025

This funding opportunity supports a wide range of research and development projects aimed at advancing technologies for national defense and air superiority, inviting participation from educational institutions, nonprofits, private industry, and small businesses.

Science and Technology
Small businesses
FY 2025 Arizona Water Protection Fund (AWPF)
$750,000
Arizona Department of Water Resources
State

Application Deadline

Aug 30, 2024

Date Added

Jul 8, 2024

The Arizona Water Protection Fund (AWPF) is a competitive state grant program that provides funding to interested parties for the development and implementation of measures to protect water of sufficient quality and quantity to maintain, enhance, and restore river and riparian resources throughout Arizona (including projects that benefit fish and wildlife that are dependent on these important resources), and measures to increase water availability and supply. Financial Notes: Matching funds are not required to be eligible for AWPF funding; however, projects that do include matching funds typically receive higher consideration.   Administrative costs must be limited to a maximum of 5% of the total AWPF project funds requested.  Subcontractors or consultants working on your project must also conform to the 5% administrative cost limit if you are paying them out of AWPF funds.   Payments are made on a cost reimbursement basis.  Appropriate documentation (e.g., receipts, invoices, reports, data, and photographs) will be required in order to receive reimbursement.   Adequate accounting practices and record keeping will be required.

Infrastructure
City or township governments
Master Announcement Instructions (MAI)
Contact for amount
Department of Health and Human Services - Advanced Research Projects Agency for Health
Federal

Application Deadline

Oct 20, 2024

Date Added

Jun 26, 2024

Amendment 1 (June 25, 2024): The purpose of this Amendment 1 is to: 1) make administrative updates to Section 1.1, 1.2, 2.1.2, 3.1, 3.2 and 5.2.6; 2) replace Section 2.1.1 with new language pertaining to Federally Funded Research and Development Centers (FFRDCs) and Government Entities. Additionally, Section 4.2, Evaluation Criteria #2 is updated to remove the reference to Government Entities (removal is not highlighted in yellow); 3) change references from Abstract to Solution Summaries (intent behind the document is unchanged); 4) update proposal submission instructions in Section 3.2; and 5) update Section 5.1 to remove the Stage 2 Notification Letter. All changes are highlighted in yellow.Also, please note that the title of this opportunity has bee revised to eliminate confusion. The opportunity should have been titled, "Master Announcement Instruction (MAI)" instead of "ARPA-H BDF Tool Box".The Master Announcement Instructions (MAI) is a new ARPA-H announcement that aims to create standard tiered proposal submission requirements, so the amount of work required to write a proposal is commensurate with the size of the proposed effort. It also aims to reduce the up-front work required to submit cost information to reduce the barrier to entry for non-traditional performers. Module announcements that link to this MAI will provide more specific instructions about how the proposal requirements vary across tiers of effort.All responsible sources capable of satisfying the Governments needs may submit a proposal to a Module Announcement. Specifically, universities, non-profit organizations, small businesses and other than small businesses are eligible and encouraged to propose to Module Announcements.NOTE: Proposals shall NOT be submitted against the MAI. Proposals shall only be submitted against a Module Announcement.

Health
Public and State controlled institutions of higher education
For the Good of Innovation Reagent Grant Program
$10,000
Bio-Techne
Private

Application Deadline

Nov 21, 2025

Date Added

Nov 14, 2025

This grant provides $10,000 in reagent credits to researchers working on innovative stem cell and organoid projects at eligible institutions, helping to advance scientific breakthroughs in these fields.

Science and Technology
Individuals
DoW Prostate Cancer, Physician Research Award
$1,100,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports early-career physician-scientists conducting innovative research to improve outcomes for patients with prostate cancer, while also fostering their professional development through mentorship.

Health
Nonprofits
DOD Lung Cancer, Concept Award
$1,920,000
DOD-AMRAA (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jun 17, 2024

Date Added

Mar 26, 2024

The intent of the FY24 LCRP Concept Award is to support innovative, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies, or applications in lung cancer. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a sound scientific rationale and study design. Research applications only in the area of mesothelioma will not be accepted.Inclusion of preliminary data is not required but is allowed. The strength of the proposed research should be based on sound scientific rationale and logical reasoning. The presentation of substantial preliminary data suggests that the proposed research project would be more appropriately submitted to a different FY24 LCRP funding opportunity. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for future research projects. Absence of preliminary data will not negatively affect scientific or programmatic review of the application.Care Delivery and Health Disparity Option: The FY24 LCRP Concept Award mechanism encourages applications that specifically address the comprehensive lung cancer care and/or health disparities FY24 LCRP Areas of Emphasis by offering a Care Delivery and Health Disparity option. Applications from the Care Delivery and Health Disparity option will be peer and programmatically reviewed separately from applications submitted to the Cancer Research Continuum option.Relevance to Military Health: The LCRP seeks to support research that is relevant to the healthcare needs of military Service Members, Veterans, and their Families. Relevance to military health will be considered in determining relevance to the mission of the Defense Health Program (DHP) and FY24 LCRP during programmatic review. Investigators are strongly encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health:Use of military or Veteran populations, biospecimens, data/databases, or programs in the proposed research Collaboration with Department of Defense (DOD) or Department of Veterans Affairs (VA) investigatorsExplanation of how the project addresses an aspect of lung cancer that has relevance or is unique to the military, Veterans, other Military Health System (MHS) beneficiaries, or Family readiness of Service Members, including environmental exposures other than tobacco.All investigators applying to FY24 LCRP funding opportunities are encouraged to consider leveraging resources from the LCRP-funded Lung Cancer Biospecimen Resource Network (LCBRN) if retrospectively collected human anatomical substances and correlated clinical data are relevant to the proposed studies. Samples from the LCBRN are currently available through the Cooperative Human Tissue Network (CHTN). To request LCBRN samples, contact the Division Coordinator for the CHTN Mid-Atlantic division (email: CHTN-MidAtl@hscmail.mcc.virginia.edu) located at the University of Virginia.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 LCRP priorities.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the VA, and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.

Science and Technology
Nonprofits
DoD Autism, Idea Development Award
$2,640,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 15, 2024

Date Added

Mar 26, 2024

The FY24 ARP Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for Autistic individuals. Applications are strongly encouraged to address one of the FY24 ARP Idea Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in ASD. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation.Research funded by the FY24 ARP should be responsive to the needs of people with ASD, their families, and/or caregivers. Researchers are therefore encouraged to establish and utilize effective collaborations and partnerships with community members to maximize the translational and impact potential of the proposed research.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in womens health outcomes and/or advancing knowledge for womens health.

Science and Technology
Nonprofits
Kidney Precision Medicine Project Tissue Interrogation Sites (U01 Clinical Trial Not Allowed)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 10, 2026

Date Added

Sep 11, 2025

This funding opportunity supports a variety of organizations in analyzing human kidney tissue samples to advance research in kidney disease and develop personalized treatment strategies.

Health
State governments
Specialty Crop Research Initiative
$10,000,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Jun 15, 2026

Date Added

Apr 14, 2026

This funding opportunity supports collaborative research and extension projects aimed at improving the productivity and sustainability of the U.S. specialty crop industry, including fruits, vegetables, and horticultural crops.

Agriculture
Public and State controlled institutions of higher education
NSF Small Business Innovation Research / Small Business Technology Transfer Phase II Programs
$1,250,000
National Science Foundation
Federal

Application Deadline

Nov 5, 2025

Date Added

Jun 2, 2025

This grant provides funding to small businesses and startups that have previously received NSF Phase I awards, helping them advance their innovative research into market-ready products and services.

Science and Technology
Small businesses
GlobalX Challenge 26.1: AI-Native Air Interface for Tactical Communication Networks
$500,000
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Aug 31, 2026

Date Added

Jun 10, 2026

This funding opportunity provides financial support for international research organizations to develop innovative AI-driven communication technologies that enhance tactical networks in challenging environments, with a focus on collaboration and measurable improvements in performance.

Science and Technology
Nonprofits
Rehabilitation Research and Training Center (RRTC) on Interventions to Promote Community Living Among People with Disabilities
$925,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Jul 29, 2026

Date Added

Sep 8, 2025

This funding opportunity supports research and training initiatives to improve community living for individuals with disabilities by addressing barriers to independence and inclusion.

Science and Technology
Nonprofits
NOAA Small Business Innovation Research (SBIR) Program- FY25 Phase I
$190,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jan 15, 2025

Date Added

Nov 18, 2024

This grant provides funding for small businesses to develop innovative technologies that support NOAA's mission in areas like climate change, coastal resilience, and water quality.

Science and Technology
Small businesses
Emerging Health Innovators (EHI) Initiative
$350,000
U.S. Department of Health & Human Services (Advanced Research Projects Agency for Health)
Federal

Application Deadline

Feb 5, 2025

Date Added

Jan 7, 2025

This initiative provides funding to early-career researchers and community organizations to develop innovative health solutions that address critical health challenges in local communities.

Science and Technology
Public and State controlled institutions of higher education
Tribal Colleges and Universities Program Hub and Topical Interest Groups
$17,500,000
National Science Foundation
Federal

Application Deadline

May 31, 2024

Date Added

Feb 22, 2024

This solicitation is offered for support of two types of projects, a TCUP Hub and faculty-led topical interest groups (TIGs). The TCUP Hub will serve the entire TCUP-eligible community with activities such as convening workshops (including the TCUP Leaders' Forum), coordinating faculty/student exchanges, organizing professional development opportunities, and overseeing TCUP Fellowship opportunities with eligible agencies. The Hub will connect people and organizations to facilitate relationships, expand and diversify networks, and support TCUP faculty and staff in building capacity in areas they identify. It will curate shared resources, expertise, and experiences to build the capacity of TCUP institutions. Also, it will build and support a sense of community among all TCUP institutions and elevate the voices within them. Only one Hub will be supported, either to a single institution or to a collaborative submission from multiple institutions. Interested parties may find that a collaborative submission from multiple institutions is more feasible, engaging two or more TCUP institutions to synergistically leverage their different strengths in realizing the Hub's mission. Multiple institutions submitting collaboratively may better address the multiplicity of TCUP institutions, which vary geographically, administratively, and in modes of governance. Clearly, some activities may be best pursued by enlisting specialists as consultants. Two types of collaborative proposals are acceptable: simultaneous submission of proposals from multiple organizations submitting a unified set of certain proposal sections, as well as information unique to each organization, such as unique budgets, key personnel, and activities; or submission of a collaborative proposal from one organization, with collaborating institutions included through subawards (subawards are permitted only to TCUP-eligible institutions; proposers should confer with the TCUP program staff prior to submission). All collaborative proposals submitted from multiple organizations must be submitted via Research.gov. Additionally, this solicitation is offered for support of independent, faculty-led topical interest groups (TIGs) that focus on professional development of faculty and formation of science, technology, engineering, and mathematics (STEM) discipline networks (e.g., engineering, genomics, Indigenous research, environmental science). Up to two new TIGs may be supported. [1] Executive Order 13021 defines Tribal Colleges and Universities ("tribal colleges") as those institutions cited in section 532 of the Equity in Educational Land-Grant Status Act of 1994 (7 U.S.C. 301 note), and other institutions that qualify for funding under the Tribally Controlled Community College Assistance Act of 1978, (25 U.S.C. 1801 et seq.), as well as Navajo Community College as authorized in the Navajo Community College Assistance Act of 1978, Public Law 95-471, Title II (25 U.S.C. 640a note). The term "Alaska Native-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 20 percent Alaska Native students. The term "Native Hawaiian-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 10 percent Native Hawaiian students. Most TCUP-eligible institutions of higher education are two-year or community colleges. See the Who May Submit Proposals section in this solicitation for further details.

Science and Technology
Public housing authorities
Catalyst Micro-Grant for Startups and Emerging Businesses in North Carolina
$2,500
Mountain BizWorks
Private

Application Deadline

Oct 11, 2024

Date Added

Sep 19, 2024

Mountain BizWorks in North Carolina is offering 20 micro-grants of $2,500 each to startups and emerging businesses owned by historically underrepresented groups, aiming to support their growth and contribution to the local community.

Business and Commerce
Small businesses
Magnetic Acceleration Generating New Innovations And Tactical Outcomes Sbir/STTR (Magnito Sbir/STTR)
$3,000,000
U.S. Department of Energy (Advanced Research Projects Agency-Energy)
Federal

Application Deadline

Not specified

Date Added

Aug 26, 2025

This funding opportunity supports U.S. small businesses in developing innovative high-performance magnetic materials for applications in motors and energy systems, with a focus on advanced computational methods and manufacturing scalability.

Science and Technology
Small businesses
Pipeline Safety Research and Development Research Announcement
Contact for amount
U.S. Department of Transportation
Federal

Application Deadline

Not specified

Date Added

Sep 22, 2025

This funding opportunity is designed for universities, nonprofits, and private companies to conduct research projects that improve pipeline safety through innovative technology and knowledge development.

Science and Technology
Nonprofits
DoD Multiple Sclerosis Investigator-Initiated Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 13, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, treatment, and quality of life for individuals affected by multiple sclerosis, particularly benefiting Service Members, Veterans, and their families.

Health
Nonprofits
Kidney Precision Medicine Project Central Hub (U24 Clinical Trial Not Allowed)
$5,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 10, 2026

Date Added

Sep 11, 2025

This funding opportunity provides financial support to a wide range of organizations to establish a central hub for coordinating research efforts aimed at improving kidney disease treatment and outcomes through precision medicine.

Health
State governments