Who May Submit Proposals: Proposals may only be submitted by the following: - Proposals may only be submitted by organizations located in the United States, its territories, or possessions, as follows.

Institutions of higher education (Ph.D.-granting and non-Ph.D.-granting), acting on behalf of their faculty members, that are accredited in and have their main campus in the United States, its territories, or possessions. Distinct academic campuses (e.g., that award their own degrees, have independent administrative structures, admissions policies, alumni associations, etc.) within multi-campus systems qualify as separate submission-eligible institutions.
Not-for-profit, non-degree-granting domestic U.S. organizations, acting on behalf of their employees, for example (but not limited to) independent museums and science centers, observatories, research laboratories and similar organizations that are directly associated with the Nation's research activities. These organizations must have an independent, permanent administrative organization (e.g., a sponsored projects office) located in the United States, its territories, or possessions, and have 501(c)(3) tax status.
Consortia as follows:

a) A legally incorporated, not-for-profit consortium that includes two or more submission-eligible organizations as described in items (1) and (2) above. Such a consortium is one with an independent administrative structure (e.g., a sponsored projects office) located in the United States, its territories, or possessions and has 501(c)(3) status.

b) Submission-eligible organizations as described in items (1) and (2) above, on behalf of an informal consortium. The Cover Sheet of such a proposal must identify both a PI and co-PI(s) from at least two Mid-scale RI-1 submission-eligible organizations (items 1 and/or 2 above) as lead investigators in the consortium. These consortium proposals may also include as partners, via subawards,other U.S. and non-U.S. organizations that are not eligible to submit Mid-scale RI-1 proposals.

In either case, the proposal title should indicate that a consortium is proposing.

For-profit commercial organizations, especially U.S. small businesses with strong capabilities in scientific or engineering research or education, are eligible for infrastructure support through subawards/subcontracts as private sector partners with submitting organizations; they may not submit proposals in response to this solicitation. Such partnerships must be substantive and meaningful and build capacity for infrastructure development withinMid-scale RI-1 submission-eligible organization(s). In addition, the value added by the for-profit commercial organization should be justified as a unique contribution that is otherwise unavailable within organizations described in (1) and (2). Unless otherwise specified in the award, title to the resulting infrastructure should be retained by the Mid-scale RI-1-eligible performing organization. Prospective PIs may contact cognizantMid-scale RI-1 program officers regarding organizational eligibility, and for information on other NSF funding opportunities for instrumentation and research infrastructure.

Additionally:

Proposals that augment MREFC projects: The Mid-scale RI-1 program will not accept proposals for an instrument or other infrastructure that augments an ongoing NSF Major Multi-user Facility or Mid-scale RI-2 project in the construction stage, since the scope of those projects is already defined. A list of Major Facilities projects is available at https://www.nsf.gov/bfa/lfo/docs/major-facilities-list.pdf and the

Grants for Private institutions of higher education - Federal