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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

The Genesis Mission: Transforming Science and Energy with AI
$16,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Dec 17, 2026

Date Added

Mar 18, 2026

This funding opportunity supports interdisciplinary teams from various sectors, including academia and industry, in developing innovative AI-driven solutions to advance scientific discovery and address complex energy and environmental challenges.

Science and Technology
Nonprofits
Affordable Housing Program (AHP) General Fund
$2,000,000
Federal Home Loan Bank of Chicago
Federal

Application Deadline

Jun 12, 2026

Date Added

May 6, 2026

This program provides forgivable grants to financial institutions and project sponsors for developing and preserving affordable housing for low- and moderate-income households in the Chicago area.

Housing
Nonprofits
U.S. Army Combat Capabilities Development Command Soldier Center Broad Agency Announcement for Basic and Applied Research
Contact for amount
U.S. Army Combat Capabilities Development Command Soldier Center
Federal
Rolling

Application Deadline

Feb 27, 2030

Date Added

Mar 18, 2025

This funding opportunity is designed to support universities, research institutes, and businesses in developing innovative technologies to enhance soldier performance and address future military challenges.

Science and Technology
Public and State controlled institutions of higher education
DoD Multiple Sclerosis Exploration-Hypothesis Development Award
$250,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 13, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at understanding and addressing multiple sclerosis, targeting both established and early-career investigators from various organizations.

Health
Nonprofits
DoD Lupus, Idea Award
$300,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 19, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at advancing the understanding and treatment of lupus, targeting scientists and organizations dedicated to improving the lives of those affected by the disease, including military personnel and their families.

Health
Nonprofits
Injury Prevention and Control Research and State and Community Based Programs - RFA-PS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for state, academic, non-profit, and business organizations to conduct research and implement programs focused on preventing and controlling injuries within communities.

Health
State governments
CHIPS Incentives Program Facilities for Semiconductor Materials and Manufacturing Equipment
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Nov 1, 2026

Date Added

Oct 17, 2025

This program provides federal funding to private-sector organizations, nonprofits, and consortia for the construction and modernization of facilities that produce semiconductor materials and manufacturing equipment, aiming to strengthen U.S. semiconductor manufacturing and security.

Science and Technology
For profit organizations other than small businesses
DoW Vision, Mentored Clinical Research Award
$75,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 10, 2026

Date Added

May 4, 2026

This funding opportunity supports military and civilian clinicians in training to conduct patient-oriented research on vision injuries and visual dysfunction related to military service, under the mentorship of established researchers.

Health
Nonprofits
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 11, 2024

This funding opportunity supports ongoing clinical trials aimed at improving the diagnosis, prevention, and treatment of dental, oral, and craniofacial diseases, encouraging applications from a wide range of eligible institutions and organizations.

Health
State governments
Critical Minerals and Materials Accelerator Notice of Funding Opportunity
$2,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Jul 23, 2026

Date Added

Apr 8, 2026

This funding opportunity provides financial support to U.S. entities, including universities and businesses, to develop and commercialize innovative technologies for producing and processing critical minerals essential for energy systems and national security.

Science and Technology
Public and State controlled institutions of higher education
Long Range Broad Agency Announcement (BAA) for NSWC Crane
Contact for amount
U.S. Department of Defense (NSWC CRANE - N00164)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 12, 2024

This grant invites innovative research proposals from academic institutions, industry partners, and research organizations to develop advanced technologies that support national security in areas like electronic warfare and hypersonic weapons.

Science and Technology
For profit organizations other than small businesses
DoD Lupus, Transformative Vision Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 19, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the quality of life for individuals living with lupus, including Service Members, Veterans, and their families, by encouraging collaboration among researchers, clinicians, and lupus advocates.

Health
Nonprofits
Supplemental and Alternative Crops
$460,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Jun 25, 2026

Date Added

May 11, 2026

This funding opportunity supports research and extension projects that promote the development and adoption of nontraditional crops, helping farmers diversify their operations and improve economic resilience across the United States.

Agriculture
Public and State controlled institutions of higher education
Discovery of in vivo Chemical Probes for the Nervous System
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Sep 30, 2025

This funding opportunity provides financial support for researchers developing innovative chemical probes to study biological processes in the nervous system, focusing on understanding brain function and neurological diseases.

Science and Technology
Public and State controlled institutions of higher education
DoW Peer Reviewed Medical, Impact Award
$3,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This funding opportunity supports researchers in developing practical medical solutions that improve health outcomes for military service members, veterans, and their families by translating scientific discoveries into clinical applications.

Science and Technology
Nonprofits
DoW Tuberous Sclerosis Complex, Exploration-Hypothesis Development Award
$350,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative researchers exploring groundbreaking ideas in tuberous sclerosis complex, aiming to generate preliminary data for future studies that benefit service members, veterans, and the public.

Health
Nonprofits
Manufacturing in America E2G Grant Initiative
$5,000,000
U.S. Small Business Administration
Federal

Application Deadline

Jun 15, 2026

Date Added

May 4, 2026

This funding opportunity provides $5 million each to organizations that deliver hands-on manufacturing training and technical assistance to small manufacturing businesses across the United States.

Business and Commerce
Nonprofits
Department of Defense HIV/AIDS Prevention Program
Contact for amount
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Sep 18, 2027

Date Added

Sep 19, 2022

This funding opportunity provides financial support to organizations that develop and implement comprehensive HIV/AIDS prevention and treatment programs for foreign military health systems, enhancing military readiness and public health outcomes.

Health
Nonprofits
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) aims to support the clinical validation of already analytically validated biomarkers and assays for cancer detection, diagnosis, and treatment monitoring, ensuring they are reliable and ready for use in clinical studies without conducting new trials.

Education
State governments
DoW Arthritis Translational Research Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 22, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research projects aimed at developing effective treatments for various forms of arthritis, particularly those that enhance the health and readiness of military personnel and benefit veterans and their families.

Health
Nonprofits