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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

International Programs Trade, Invasive Species Program Funding Opportunity
$250,000
U.S. Department of Agriculture (Forest Service)
Federal

Application Deadline

Sep 30, 2026

Date Added

Aug 4, 2026

This funding opportunity provides financial support to organizations working on innovative strategies to prevent and manage invasive species that threaten U.S. forests, agriculture, and ecosystems, with a focus on international collaboration.

Environment
Nonprofits
DoW Tick-Borne Disease Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 22, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, diagnosis, and treatment of Lyme disease and other tick-borne diseases, targeting both established and early-career researchers.

Health
Nonprofits
Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2027

Date Added

May 15, 2025

This funding opportunity supports U.S. institutions in training and developing the next generation of researchers focused on kidney, urologic, and hematologic diseases through collaborative networks and mentorship programs.

Science and Technology
Public and State controlled institutions of higher education
Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 25, 2027

Date Added

Nov 6, 2024

This funding opportunity supports researchers in planning cancer prevention and control clinical trials by providing resources to gather essential data for future studies aimed at improving public health outcomes.

Health
State governments
NASA Innovative Advanced Concepts (NIAC) Phase II
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Not specified

Date Added

May 15, 2026

This funding opportunity supports innovative research and development projects that advance space technology, inviting a diverse range of applicants, including universities, nonprofits, and private companies, to explore high-risk, high-reward concepts for future NASA missions.

Science and Technology
Nonprofits
Research Experiences for Undergraduates
$155,000
National Science Foundation
Federal

Application Deadline

Aug 18, 2027

Date Added

Aug 30, 2024

This program provides funding for colleges and universities to engage undergraduate students in hands-on research experiences across various scientific fields, with a focus on supporting those from underrepresented backgrounds.

Education
Public and State controlled institutions of higher education
Assisting Specialty Crop Exports: Low Oxygen Storage and Packaging Systems for U.S. Tree Nuts with Phytosanitary Traceability
$2,000,000
U.S. Department of Agriculture (Foreign Agricultural Service)
Federal

Application Deadline

Oct 26, 2026

Date Added

Aug 25, 2026

This funding opportunity provides financial support for U.S. organizations to develop innovative low-oxygen storage and packaging solutions for tree nuts, enhancing export quality and compliance with international phytosanitary standards.

Agriculture
State governments
The Genesis Mission: Transforming Science and Energy with AI
$11,250,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Dec 17, 2026

Date Added

Mar 18, 2026

This funding opportunity provides financial support for interdisciplinary teams, including universities, nonprofits, and private companies, to develop innovative AI-driven solutions that enhance scientific research and energy efficiency in various fields.

Science and Technology
Public and State controlled institutions of higher education
U.S. Army Combat Capabilities Development Command Soldier Center Broad Agency Announcement for Basic and Applied Research
Contact for amount
U.S. Army Combat Capabilities Development Command Soldier Center
Federal
Rolling

Application Deadline

Feb 27, 2030

Date Added

Mar 18, 2025

This funding opportunity is designed to support universities, research institutes, and businesses in developing innovative technologies to enhance soldier performance and address future military challenges.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-PS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for state, academic, non-profit, and business organizations to conduct research and implement programs focused on preventing and controlling injuries within communities.

Health
State governments
CHIPS Incentives Program Facilities for Semiconductor Materials and Manufacturing Equipment
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Nov 1, 2026

Date Added

Oct 17, 2025

This program provides federal funding to private-sector organizations, nonprofits, and consortia for the construction and modernization of facilities that produce semiconductor materials and manufacturing equipment, aiming to strengthen U.S. semiconductor manufacturing and security.

Science and Technology
For profit organizations other than small businesses
Oligonucleotide Toxicity (OligoTox) Open Data Challenge
$500,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Dec 31, 2026

Date Added

Dec 24, 2025

This grant encourages researchers to create and share high-quality datasets that improve the prediction of toxicity in oligonucleotide therapeutics, particularly using human-based testing methods.

Science and Technology
Nonprofits
DoW Vision, Mentored Clinical Research Award
$75,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 10, 2026

Date Added

May 4, 2026

This funding opportunity supports military and civilian clinicians in training to conduct patient-oriented research on vision injuries and visual dysfunction related to military service, under the mentorship of established researchers.

Health
Nonprofits
Contaminated Alaska Native Claims Settlement Act Lands Assistance Program
$8,000,000
U.S. Environmental Protection Agency
Federal

Application Deadline

Dec 31, 2029

Date Added

Dec 28, 2023

This program provides financial assistance to Alaska Native organizations for the assessment and cleanup of contaminated lands conveyed under the Alaska Native Claims Settlement Act, ensuring the protection of human health and the environment.

Environment
Native American tribal organizations
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 11, 2024

This funding opportunity supports ongoing clinical trials aimed at improving the diagnosis, prevention, and treatment of dental, oral, and craniofacial diseases, encouraging applications from a wide range of eligible institutions and organizations.

Health
State governments
ROSES25: A.15 Biosphere
$10,000,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Nov 6, 2026

Date Added

Jul 21, 2026

This funding opportunity supports U.S. organizations conducting research on ecosystems and biodiversity using NASA's remote sensing data to better understand environmental changes and their impacts.

Science and Technology
Public and State controlled institutions of higher education
DoW Bone Marrow Failure, Investigator-Initiated Research Award
$1,250,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding and treatment of inherited and acquired bone marrow failure diseases, targeting researchers and organizations dedicated to advancing biomedical science in this field.

Science and Technology
Nonprofits
NIH Research Education Program - Courses, Curriculum Methods (Parent R25 - Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2026

Date Added

Jun 12, 2025

This funding opportunity supports educational programs that enhance the training of individuals in biomedical, behavioral, and clinical research, aiming to improve research skills and develop innovative instructional methods.

Education
Public and State controlled institutions of higher education
Long Range Broad Agency Announcement (BAA) for NSWC Crane
Contact for amount
U.S. Department of Defense (NSWC CRANE - N00164)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 12, 2024

This grant invites innovative research proposals from academic institutions, industry partners, and research organizations to develop advanced technologies that support national security in areas like electronic warfare and hypersonic weapons.

Science and Technology
For profit organizations other than small businesses
Institute of Education Sciences (IES): National Center for Special Education Research (NCSER): Using Longitudinal Data to Support State Education Policymaking in Special Education
$1,200,000
U.S. Department of Education
Federal

Application Deadline

Oct 1, 2026

Date Added

Aug 7, 2026

This grant provides funding to state agencies and eligible organizations to utilize longitudinal data systems for improving educational outcomes and policies for learners with disabilities from infancy through postsecondary education.

Education
State governments