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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

NEA/AC Regional Annual Program Statement
$30,000,000
U.S. Department of State (Bureau of Near Eastern Affairs)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 1, 2026

This funding opportunity provides financial support for innovative foreign assistance programs that enhance U.S. economic and diplomatic interests while benefiting partner countries in sectors like energy, technology, and infrastructure.

Business and Commerce
Nonprofits
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
$11,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 20, 2029

Date Added

May 29, 2025

This funding opportunity supports the development of safe, non-addictive pain treatments through innovative small molecules and biologics, targeting researchers and organizations focused on translational science in pain management.

Health
Public and State controlled institutions of higher education
Child Protection Compact Annual Program Statement
$10,000,000
U.S. Department of State (Office to Monitor-Combat Trafficking in Persons)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jun 19, 2026

This grant provides funding to organizations working to combat child trafficking in partnership with foreign governments, focusing on prevention, protection, and prosecution efforts in targeted countries.

International Development
Nonprofits
DoW Parkinsons, Investigator-Initiated Research Award
$2,000,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Nov 6, 2026

Date Added

Jun 19, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding and treatment of Parkinson's disease, targeting diverse organizations and independent researchers dedicated to advancing medical knowledge and interventions.

Science and Technology
Nonprofits
Department of Defense HIV/AIDS Prevention Program
Contact for amount
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Sep 18, 2027

Date Added

Sep 19, 2022

This funding opportunity provides financial support to organizations that develop and implement comprehensive HIV/AIDS prevention and treatment programs for foreign military health systems, enhancing military readiness and public health outcomes.

Health
Nonprofits
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) aims to support the clinical validation of already analytically validated biomarkers and assays for cancer detection, diagnosis, and treatment monitoring, ensuring they are reliable and ready for use in clinical studies without conducting new trials.

Education
State governments
DoW Arthritis Translational Research Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 22, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research projects aimed at improving arthritis care and enhancing the health and readiness of military personnel, veterans, and their families.

Health
Nonprofits
FY 2024 2026 Broad Agency Announcement (BAA), National Marine Fisheries Service
Contact for amount
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 30, 2024

This funding opportunity supports innovative projects and research aimed at sustainable fisheries management, protected species recovery, and marine ecosystem enhancement, targeting a wide range of applicants including educational institutions, nonprofits, and government entities.

Environment
State governments
National Science Foundation X-Labs Grant Program
$150,000,000
National Science Foundation
Federal

Application Deadline

May 14, 2028

Date Added

May 15, 2026

This initiative provides funding to interdisciplinary research teams in the U.S. to develop innovative platform technologies that can drive significant advancements in science and technology.

Science and Technology
For profit organizations other than small businesses
DoW Toxic Exposures Investigator Initiated Research Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 19, 2026

Date Added

May 8, 2026

This funding opportunity provides financial support for researchers investigating health issues related to toxic exposures experienced by military personnel, veterans, and their families.

Science and Technology
Nonprofits
NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed) PAR-25-416
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 14, 2027

Date Added

May 14, 2025

This funding opportunity supports the development and maintenance of shared biomedical research resources that provide advanced technologies and services to researchers across multiple states or nationally, ensuring broad access for academic investigators.

Science and Technology
State governments
Sheep Production and Marketing Grant Program FY 2026
$2,400,000
U.S. Department of Agriculture (Agricultural Marketing Service)
Federal

Application Deadline

Oct 2, 2026

Date Added

Jul 30, 2026

This funding opportunity provides financial support to national organizations that will manage subawards for projects aimed at improving sheep production, marketing, and sustainability across the United States.

Agriculture
Nonprofits
Cooperative Centers for Experimental Hematology (CCEHs) (U54- Clinical Trial Not Allowed)
$3,250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 30, 2026

Date Added

Sep 30, 2025

This funding opportunity provides resources to research institutions for developing collaborative centers focused on advancing the study of nonmalignant hematologic diseases and enhancing access to innovative technologies and expertise in the field.

Health
Public and State controlled institutions of higher education
Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
$1,300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2028

Date Added

Jun 10, 2025

This funding opportunity supports the establishment and maintenance of specialized centers that provide high-quality laboratory animals and biological materials to enhance biomedical research across various scientific fields in the United States.

Health
Public and State controlled institutions of higher education
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
$4,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 3, 2027

Date Added

Dec 6, 2024

This funding opportunity supports researchers in analyzing existing data to better understand substance use behaviors and related health issues, particularly focusing on health disparities and innovative analytical methods.

Health
Public and State controlled institutions of higher education
Agriculture Risk Management Education Partnerships Competitive Grants Program
$2,121,750
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Sep 21, 2026

Date Added

Aug 21, 2026

This program provides funding to educational organizations and institutions to deliver risk management training and resources to U.S. farmers, ranchers, and agricultural producers, helping them make informed decisions to enhance their business profitability.

Agriculture
Public and State controlled institutions of higher education
Institute of Education Sciences (IES): National Center for Education Research (NCER): Using Longitudinal Data to Support State Education Policymaking
$1,200,000
U.S. Department of Education
Federal

Application Deadline

Oct 1, 2026

Date Added

Aug 7, 2026

This grant provides funding to state agencies and research institutions to utilize statewide longitudinal data systems for improving education policies and practices that enhance student outcomes across various educational levels.

Education
State governments
Emergency Assistance for Fundamental Freedom Defenders
$983,500
U.S. Department of State (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Sep 8, 2026

Date Added

Aug 25, 2026

This funding opportunity provides emergency assistance to individuals and organizations worldwide facing imminent threats due to their efforts in promoting and defending fundamental freedoms, such as freedom of speech and peaceful assembly.

Social Advocacy
Nonprofits
DoW Bone Marrow Failure, Resource Development Award
$1,250,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 18, 2026

This funding opportunity supports the development of a comprehensive resource for researchers to advance the understanding and treatment of bone marrow failure diseases by creating a multiomic atlas from human samples.

Science and Technology
Nonprofits
DoW Peer Reviewed Cancer, Idea Award
$600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 5, 2026

Date Added

May 7, 2026

This funding opportunity supports innovative cancer research projects that aim to improve understanding and treatment options for military personnel, veterans, and their families.

Health
Nonprofits