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Grants for Small businesses - Federal

Explore 1,841 grant opportunities

NASA Innovative Advanced Concepts (NIAC) Phase II
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Not specified

Date Added

May 15, 2026

This funding opportunity supports innovative research and development projects that advance space technology, inviting a diverse range of applicants, including universities, nonprofits, and private companies, to explore high-risk, high-reward concepts for future NASA missions.

Science and Technology
Nonprofits
Research Experiences for Undergraduates
$155,000
National Science Foundation
Federal

Application Deadline

Aug 19, 2026

Date Added

Aug 30, 2024

This program provides funding for colleges and universities to engage undergraduate students in hands-on research experiences across various scientific fields, with a focus on supporting those from underrepresented backgrounds and institutions with limited STEM opportunities.

Education
Public and State controlled institutions of higher education
FY26 Preparing for Active Shooter Situations (PASS)
$10,350,000
U.S. Department of Justice (Community Oriented Policing Services)
Federal

Application Deadline

Aug 4, 2026

Date Added

Jun 10, 2026

This funding opportunity provides financial support for training programs that prepare law enforcement, first responders, and mental health professionals to effectively handle active shooter situations and improve community resilience nationwide.

Law Justice and Legal Services
State governments
The Genesis Mission: Transforming Science and Energy with AI
$293,760,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Dec 17, 2026

Date Added

Mar 18, 2026

This funding opportunity provides financial support for interdisciplinary teams, including universities, nonprofits, and businesses, to develop and implement AI-driven solutions that address critical challenges in energy, environmental, and national security sectors.

Science and Technology
Nonprofits
U.S. Army Combat Capabilities Development Command Soldier Center Broad Agency Announcement for Basic and Applied Research
Contact for amount
U.S. Army Combat Capabilities Development Command Soldier Center
Federal
Rolling

Application Deadline

Feb 27, 2030

Date Added

Mar 18, 2025

This funding opportunity is designed to support universities, research institutes, and businesses in developing innovative technologies to enhance soldier performance and address future military challenges.

Science and Technology
Public and State controlled institutions of higher education
DoD Multiple Sclerosis Exploration-Hypothesis Development Award
$250,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 13, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at understanding and addressing multiple sclerosis, targeting both established and early-career investigators from various organizations.

Health
Nonprofits
DoD Lupus, Idea Award
$300,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 19, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at advancing the understanding and treatment of lupus, targeting scientists and organizations dedicated to improving the lives of those affected by the disease, including military personnel and their families.

Health
Nonprofits
Injury Prevention and Control Research and State and Community Based Programs - RFA-PS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for state, academic, non-profit, and business organizations to conduct research and implement programs focused on preventing and controlling injuries within communities.

Health
State governments
OVC FY 2026 Increasing Services for American Indian and Alaska Native Victims of Human Trafficking in Urban Centers Program
$450,000
U.S. Department of Justice (Office for Victims of Crime)
Federal

Application Deadline

Jul 23, 2026

Date Added

May 29, 2026

This funding opportunity provides financial support to organizations that deliver essential services to American Indian and Alaska Native victims of human trafficking living in urban areas.

Income Security and Social Services
Native American tribal organizations
CHIPS Incentives Program Facilities for Semiconductor Materials and Manufacturing Equipment
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Nov 1, 2026

Date Added

Oct 17, 2025

This program provides federal funding to private-sector organizations, nonprofits, and consortia for the construction and modernization of facilities that produce semiconductor materials and manufacturing equipment, aiming to strengthen U.S. semiconductor manufacturing and security.

Science and Technology
For profit organizations other than small businesses
Oligonucleotide Toxicity (OligoTox) Open Data Challenge
$500,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Dec 31, 2026

Date Added

Dec 24, 2025

This grant encourages researchers to create and share high-quality datasets that improve the prediction of toxicity in oligonucleotide therapeutics, particularly using human-based testing methods.

Science and Technology
Nonprofits
DoW Vision, Mentored Clinical Research Award
$75,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 10, 2026

Date Added

May 4, 2026

This funding opportunity supports military and civilian clinicians in training to conduct patient-oriented research on vision injuries and visual dysfunction related to military service, under the mentorship of established researchers.

Health
Nonprofits
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 11, 2024

This funding opportunity supports ongoing clinical trials aimed at improving the diagnosis, prevention, and treatment of dental, oral, and craniofacial diseases, encouraging applications from a wide range of eligible institutions and organizations.

Health
State governments
F26AS00062: Great Lakes Fish and Wildlife Restoration Act FY 2026
$500,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Aug 3, 2026

Date Added

Jun 2, 2026

This grant provides financial support to various organizations and governments for projects that restore and protect fish and wildlife habitats in the Great Lakes Basin.

Natural Resources
State governments
DoW Bone Marrow Failure, Investigator-Initiated Research Award
$1,250,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding and treatment of inherited and acquired bone marrow failure diseases, targeting researchers and organizations dedicated to advancing biomedical science in this field.

Science and Technology
Nonprofits
Critical Minerals and Materials Accelerator Notice of Funding Opportunity
$2,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Jul 23, 2026

Date Added

Apr 8, 2026

This funding opportunity provides financial support to U.S. entities, including universities and businesses, to develop and commercialize innovative technologies for producing and processing critical minerals essential for energy systems and national security.

Science and Technology
Public and State controlled institutions of higher education
Long Range Broad Agency Announcement (BAA) for NSWC Crane
Contact for amount
U.S. Department of Defense (NSWC CRANE - N00164)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 12, 2024

This grant invites innovative research proposals from academic institutions, industry partners, and research organizations to develop advanced technologies that support national security in areas like electronic warfare and hypersonic weapons.

Science and Technology
For profit organizations other than small businesses
DoD Lupus, Transformative Vision Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 19, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the quality of life for individuals living with lupus, including Service Members, Veterans, and their families, by encouraging collaboration among researchers, clinicians, and lupus advocates.

Health
Nonprofits
DoW Peer Reviewed Medical, Impact Award
$3,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This funding opportunity supports researchers in developing practical medical solutions that improve health outcomes for military service members, veterans, and their families by translating scientific discoveries into clinical applications.

Science and Technology
Nonprofits
NEA/AC Regional Annual Program Statement
$30,000,000
U.S. Department of State (Bureau of Near Eastern Affairs)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 1, 2026

This funding opportunity provides financial support for innovative projects that promote U.S. economic interests and partnerships in the Near East, targeting sectors like energy, telecommunications, and artificial intelligence.

Business and Commerce
Nonprofits