Grants for Small businesses - Federal

This funding opportunity supports long-term, investigator-led clinical trials aimed at advancing research in allergy, infectious diseases, and aging, available to a wide range of eligible institutions both in the U.S. and internationally.

The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with the National Institute of Mental Health (NIMH), intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications that propose the development and early stage validation of novel humanized small animal models and/or human cellular microphysiological systems for NeuroHIV preclinical research. The goal of this initiative is to promote a significant improvement in the translational relevance of NeuroHIV models, specifically in the context of chronic HIV infection of the central nervous system (CNS) in the modern antiretroviral therapy (ART) era under conditions of viral suppression. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Summer 2024 with an expected application due date in Fall 2024. This NOFO will utilize the R61/R33 activity code. Details of the planned NOFO are provided below.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in advancing freedom of association and improving working conditions in the palm oil sector in Indonesia.

This funding opportunity supports researchers and institutions developing innovative organ-on-a-chip technologies to advance disease modeling and preclinical studies in dental, oral, and craniofacial health.

The United States Agency for International Development (USAID) is seeking applications for a Cooperative Agreement with a Total Estimated Amount of $45,000,000 from qualified entities to implement the program entitled Strengthening Integrated Health Services Activity (SIHSA) in Sierra Leone.USAID anticipates awarding a five-year cooperative agreement (CA) to advance and sustain improved health outcomes for Sierra Leoneans with a focus on, but not limited to: children under five, pregnant and postpartum women, youth and especially adolescent girls, and women and children living in hard-to-reach areas with limited access to health services. Special attention will be paid to those especially vulnerable within these groups, such as the disabled, gender andsexual minorities (GSM), and ethnic and religious minorities.SIHSA seeks to build a sustainable and resilient health system response to improving access, quality, and effectiveness of family planning (FP), reproductive health (RH), maternal, newborn and child health (MNCH), adolescent health, and malaria services. In addition, SIHSA aims at strengthening communities;apos; active engagement for community-driven solutions to improve health outcomes. Finally, SIHSA seeks to promote a paradigm shift within the health system, supporting system-wide action, especially at community and district levels, including reforms that act on the foundations of the health system and create opportunities for partnering with the local civil society and private sector for improved health outcomes.

This funding opportunity supports innovative research projects that improve the early diagnosis and prognosis of Alzheimer’s disease and related dementias, emphasizing community collaboration and inclusivity for underrepresented populations.

With this solicitation, BJA is seeking applications to support DOJs Global Justice Information Sharing Initiative (Global) to engage the full range of criminal justice policymakers and practitioners in the development of innovative strategies to improve the justice information and criminal intelligence sharing and technology capabilities of state, local, Tribal, territorial agencies and associated disciplines.

This grant provides funding for research projects that develop and validate clinical outcomes and biomarkers to improve the understanding and treatment of Amyotrophic Lateral Sclerosis (ALS), with a focus on community collaboration and non-interventional studies.

The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research. The Paleoclimate program of the Division of the Atmospheric and Geospace Sciences together with other Divisions in the Geoscience Directorate have joined in coordinating and supporting the annual Paleo Perspectives on Present and Projected Climate (P4CLIMATE) competition with the objectives to support studies within two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks. Researchers are encouraged to consider the P4CLIMATE competition as a possible source of support for their global change research. Since proposals eligible for funding in the P4CLIMATE competition are not eligible for funding in the Paleoclimate Program, researchers are strongly advised to contact the Directors of the Paleoclimate Program for guidance as to the suitability of their proposed research for either program. The paleoclimate program strongly encourages proposals from: Researchers at all career stages, including through the AGS Postdoctoral Research Fellowship program. Researchers at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. Researchers from traditionally underrepresented groups in Paleoclimate Science.

Grant Title: Ending the Epidemic: New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R34 Clinical Trial Optional) aims to support the development and testing of integrated healthcare models that combine HIV/AIDS, Hepatitis, addiction treatment, and primary care services to improve health outcomes for individuals at risk for or living with these conditions.

This program provides funding for collaborative research projects that use computational methods to explore and understand brain function, targeting interdisciplinary teams from U.S. and international institutions.

This grant provides funding for research and initiatives that address the impacts of drought and climate change, aiming to enhance resilience and inform decision-making for communities and ecosystems across the United States.

The PRMRP Discovery Award is intended to support innovative, untested, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies, or applications. The proposed project may be exploratory, hypothesis-driven, or hypothesis-generating research but must be novel and must be based on a strong scientific rationale and a well-developed study design and plan of analysis. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation or product development. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for groundbreaking future research projects.This award is not intended to support/validate ongoing research and inclusion of preliminary data is not allowed. Inclusion of preliminary data other than serendipitous finding is not consistent with the exploratory nature of this award. Applicants seeking funding for research to further an existing research project should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.

This funding opportunity supports researchers in developing and testing innovative medical devices aimed at treating or diagnosing conditions affecting the nervous and neuromuscular systems.

This funding opportunity supports multidisciplinary teams in developing innovative bioengineering technologies to address specific biomedical challenges, with eligibility for a wide range of organizations including universities, nonprofits, and small businesses.

This funding opportunity provides financial support to various organizations to develop and implement evidence-based self-management programs that improve health knowledge and reduce complications for individuals affected by blood disorders like hemophilia and thalassemia.

The National Institute of Mental Health (NIMH) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications encouraging foundational research projects that seek to refine and test valid methods for characterizing preteen suicide risk and protective factors across multiple domains, and for operationalizing suicide thoughts and behavior (STBs) and nonsuicidal self-injury (NSSI) among preteen youth (ages 8-12). An emphasis is placed on the inclusion of sub-populations of youth that experience health disparities and may have been underrepresented in prior youth suicide research. Studies may focus on developing new or adapting developmentally and culturally appropriate methods for assessing and characterizing risk and protective factors, examining the acceptability and utility of existing assessment methods, evaluating the relevance of risk and protective factors for diverse preteen youth and their families, modeling risk-factor trajectories, and refining sampling strategies. The research projects funded through this announcement will participate in a research consortium with other R01 recipients. In addition, each research site will work with the Data Coordinating Center (DCC) site (supported by a companion announcement) to share and analyze data, recommend candidate measures that will be included as common data elements in future research and practice contexts,and identify optimal approaches for sampling individuals from underrepresented backgrounds. This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects, and to consult with NIH in order to submit responsive applications. The NOFO is expected to be published in Summer 2023, with an expected application due date in Fall 2023. This NOFO will utilize the R01 activity code. Details of the planned NOFO are provided below.

This grant provides funding for U.S.-based organizations to develop and implement innovative tools that use Earth observation data to improve water resource management and address challenges like drought and water scarcity, in collaboration with end users such as water management agencies and utilities.

This grant provides funding for early-stage research on how mitochondrial dysfunction affects aging and immune health in individuals with HIV and substance use disorders, aiming to uncover potential therapeutic strategies.

This funding opportunity supports research projects that develop and implement effective strategies to reduce overdose deaths and improve addiction treatment across various settings, targeting diverse populations and addressing health disparities.