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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Electronics, Photonics and Magnetic Devices
$44,434,393
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for researchers developing innovative electronic, photonic, and magnetic devices to advance technology in areas like communication, healthcare, and energy.

Science and Technology
For profit organizations other than small businesses
Notice of Intent to Publish a Notice of Funding Opportunity for National Cancer Institute's Specialized Programs of Research Excellence (SPOREs) in Cancer Health Disparities and Minority Health (U54 Clinical Trial Optional)
$1,600,000
U.S. Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Sep 25, 2024

Date Added

Dec 21, 2023

The National Cancer Institute (NCI) intends to issue the U54 Specialized Programs of Research Excellence in Cancer Health Disparities and Minority Health (CHD-MH SPORE) notice of funding opportunity (NOFO). The program will support a network of multidisciplinary, multi-institutional U54 CHD-MH SPOREs, which are multi-project awards uniquely focused on health disparities and/or minority health translational research for improved prevention, early detection, diagnosis, and treatment of cancer in populations who are underserved. U54 CHD-MH SPOREs can investigate more than one cancer type in underserved populations, including groups of highly related cancers (e.g., gastrointestinal or head and neck). The research supported through this program must be translational and must stem from research on human biology, addressing the interplay of various determinants of health with the biology of the disease. U54 CHD-MH SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant, which may include a clinical trial. This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications. The NOFO is expected to be published in late winter 2024 with only one expected application due date in late September 2024.

Health
State governments
DRL FY 2025 China Programs
$2,466,699
U.S. Department of State (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Aug 31, 2026

Date Added

Aug 5, 2026

This funding opportunity provides financial support to organizations working to address human rights abuses and promote fundamental freedoms in China, including efforts against censorship, legal repression, and sanctions evasion.

International Development
Nonprofits
The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 20, 2025

Date Added

Oct 28, 2024

This grant provides funding for research projects that explore the complex processes of cancer metastasis, encouraging collaboration among institutions to improve understanding and treatment of metastatic diseases.

Education
State governments
Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 24, 2025

Date Added

Nov 14, 2024

This funding opportunity supports research on policies affecting tobacco, alcohol, and cannabis use in underserved communities, aiming to promote health equity and reduce disparities in substance exposure and use.

Education
State governments
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 16, 2025

Date Added

May 9, 2022

This funding opportunity provides financial support for research aimed at improving the spread and implementation of effective health interventions, particularly in underserved communities, with a focus on promoting health equity and addressing health disparities.

Education
State governments
Elder Justice Innovation Grants FY2026
$500,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support for U.S.-based organizations to develop innovative projects that prevent and address elder abuse, neglect, and exploitation, ultimately enhancing the well-being of older adults.

Income Security and Social Services
Nonprofits
FY 2026 Ocean Technology Transition Program
$1,200,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jul 15, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for universities, nonprofits, and government entities to develop and operationalize advanced ocean and coastal observing technologies that enhance data collection and environmental monitoring.

Environment
Public and State controlled institutions of higher education
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
$275,766
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 4, 2025

Date Added

Sep 15, 2022

This funding opportunity supports small businesses in developing innovative, non-addictive therapies and technologies for effective pain management, addressing the urgent need for alternatives to opioid treatments.

Health
Small businesses
FY25 Ensuring Research Integrity - Conferences and Workshops Program (CWP)
$50,000
U.S. Department of Health & Human Services (Office of the Assistant Secretary for Health)
Federal

Application Deadline

Jul 30, 2025

Date Added

Jul 4, 2025

This funding opportunity provides financial support for organizations to host conferences and workshops that promote research integrity and ethical practices in research across various disciplines.

Health
City or township governments
2025 "$100,000 Start an SUD Startup" Challenge
$10,000
U.S. Department of Health and Human Services (National Institute on Drug Abuse)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This grant provides funding and mentorship to interdisciplinary teams developing innovative solutions for drug use and substance use disorders, aiming to support the formation of early-stage biotech startups in the U.S.

Health
Individuals
Environmental Security Technology Certification Program
$10,000,000
Environmental Security Technology Certification Program
Federal

Application Deadline

Aug 21, 2026

Date Added

Aug 26, 2025

This funding opportunity is designed for businesses, universities, and nonprofits to develop and demonstrate innovative technologies that improve environmental and energy efficiency for the U.S. Department of Defense.

Science and Technology
Small businesses
Defense Production Act Title III Expansion of Domestic Production Capability and Capacity
$25,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

Jul 12, 2026

Date Added

Jul 12, 2019

This funding opportunity provides financial support to U.S. companies and organizations to boost domestic production capabilities for critical defense materials and technologies, ensuring national security and resilience in the industrial base.

Science and Technology
For profit organizations other than small businesses
Restoring Reliability: Coal Recommissioning and Modernization
$175,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Feb 11, 2026

Date Added

Oct 6, 2025

This funding opportunity provides financial support to domestic entities that own or operate coal-fired power plants, enabling them to recommission, modernize, or retrofit their facilities to enhance grid reliability and support energy needs in rural communities.

Energy
For profit organizations other than small businesses
Supporting the implementation of comprehensive HIV prevention and treatment programs to achieve and sustain epidemic control in Zimbabwe under the President's Emergency Plan for AIDS Relief (PEPFAR)
$10,000,000
U.S. Department of Health & Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 18, 2025

Date Added

Jul 22, 2024

This funding opportunity provides financial support to local organizations in Zimbabwe to implement comprehensive HIV prevention and treatment programs, focusing on key populations and improving health services to achieve and maintain epidemic control.

Health
State governments
Centers for Precision Disease Modeling (U54) (Clinical Trials Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 15, 2024

Date Added

Oct 7, 2024

This funding opportunity supports the establishment of research centers that create advanced animal models for studying diseases, enabling better translation of genetic research into human health applications, and is open to a variety of eligible institutions and organizations.

Health
State governments
Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 16, 2025

Date Added

Nov 19, 2024

This funding opportunity supports innovative research projects focused on developing and testing radionuclide-based cancer therapies, particularly in preclinical settings, to improve treatment outcomes and understanding of their effects on tumors and normal tissues.

Education
State governments
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
Defense Advanced Research Projects Agency (DARPA
Federal

Application Deadline

Sep 5, 2025

Date Added

Mar 18, 2025

This funding opportunity seeks innovative research proposals from various entities, including businesses and universities, to develop groundbreaking technologies for national security, focusing on areas like novel materials, quantum computing, and artificial intelligence.

Science and Technology
Small businesses
Engineering Environmental Resiliency (EER)
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Apr 27, 2026

This program provides funding for U.S.-based researchers and institutions to develop innovative technologies and processes that enhance environmental sustainability and resilience while promoting efficient resource use.

Science and Technology
Public and State controlled institutions of higher education
DoD, Melanoma, Team Science Award
$1,500,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 26, 2024

Date Added

May 9, 2024

Key aspects of the TSA: Multidisciplinary Collaboration: The success of the project should depend on the unique skills and perspectives of each partner. The application must clearly define the synergistic components that will facilitate and accelerate progress in melanoma in a way that could not be accomplished through independent efforts. The plans for interactions among all PIs and institutions involved must be clearly articulated. Collectively, the members of the research team should represent the appropriate diversity of expertise necessary for addressing the proposed research question. Participating institutions must be willing to resolve potential intellectual and material property issues and remove institutional barriers to achieving high levels of cooperation. The following components of the proposed multidisciplinary collaboration are encouraged but not required: It is strongly encouraged that the research team has a least one investigator, key personnel, or consultant who can provide input on the ultimate utility/applicability (short- or long-term) of the anticipated outcome(s) to the melanoma field and/or patient care. The inclusion of an early-career investigator is encouraged. An early-career investigator is defined as an independent, early-career researcher or physician-scientist within 7 years of receiving their first faculty appointment by the time of the full application deadline. Investigators in mentored positions, (e.g., postdoctoral fellows) are not eligible to be named as a PI on a TSA application. The inclusion of a military and/or U.S. Department of Veterans Affairs (VA) investigator is encouraged. A military or VA investigator is defined as an investigator who is active-duty, active reserve, active duty detailed to agencies outside of the Department of Defense (DOD), civilian DOD investigators, or an investigator at a VA research facility. If included as PI on the research team, the military/VA investigator should have a substantial role in the research and should not be included only for access to active-duty military and/or VA populations. Impact: The application must articulate the impact the proposed work, including basic research, will have on melanoma research and/or patient care. Outcomes from this award are expected to expedite the advancement of promising ideas toward clinical applications and/or improve the current state of the science/technology in the melanoma field. The proposed research must relate to at least one of the FY24 MRP Focus Areas in Section II.A.1. Preliminary Data Required: Applications must include preliminary data to support feasibility of the study. However, these data do not necessarily need to be derived from melanoma studies. Any unpublished, preliminary data presented should originate from the laboratory of at least one of the PIs or other member(s) of the research team.

Science and Technology
Nonprofits