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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

BJA FY24 National Ashanti Alert Network Training and Technical Assistance Program
$1,000,000
USDOJ-OJP-BJA (Bureau of Justice Assistance)
Federal

Application Deadline

Jul 17, 2024

Date Added

Jun 11, 2024

With this solicitation, BJA is seeking applications for funding under the Ashanti Alert National Network Training and Technical Assistance Program. This program will assist in completing the elements set forth in the Ashanti Alert Act for the development, implementation, and maintenance of this national communication system to assist with the reporting and location of missing adults over the age of 17.

Law Justice and Legal Services
Nonprofits
DOD Spinal Cord Injury Research Program Translational Research Award
$10,320,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 30, 2024

Date Added

Mar 26, 2024

The SCIRP TRA is intended to support translational research that will accelerate the movement of promising ideas in SCI research into clinical applications. Although not all-inclusive, some examples include demonstration studies of pharmaceuticals and medical devices in preclinical systems and/or clinical research on therapeutics, devices, or practice using human tissues or resources.The ultimate goal of translational research is to move an observation forward into clinical application and accelerate the clinical introduction of health care products, technologies, or practice guidelines. Observations that drive a research idea may be derived from a laboratory discovery, population-based studies, or a clinicians first-hand knowledge of patients and anecdotal data. However, applicants should not view translational research as a one-way continuum from bench to bedside. The research plan is encouraged to involve a reciprocal flow of ideas and information between basic and clinical science.

Science and Technology
Nonprofits
NIST MEP Disaster Assessment Program
$1,000,000
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

May 8, 2026

Date Added

Jun 20, 2024

This funding opportunity provides financial support to Manufacturing Extension Partnership Centers to help small- and medium-sized manufacturers recover and improve resilience after major disasters.

Disaster Prevention and Relief
Nonprofits
Resilient Software Systems Capstone
$3,000,000
Defense Advanced Research Projects Agency
Federal

Application Deadline

Nov 5, 2025

Date Added

Sep 8, 2025

This initiative provides funding to defense contractors and formal methods developers to enhance cybersecurity in military software systems by integrating advanced verification tools.

Science and Technology
For profit organizations other than small businesses
Supporting life-saving HIV services and related health systems in Zambia on a pathway to self-reliance under the Presidents Plan for AIDS Relief (PEPFAR)
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 17, 2026

Date Added

Oct 17, 2025

This funding opportunity provides financial support to a variety of organizations to enhance HIV prevention, care, and treatment services in Zambia, while strengthening the local health systems and promoting national ownership of these initiatives.

Health
State governments
Infrastructure Investment and Jobs Act (IIJA) Mines Metals Capacity Expansion Piloting Byproduct Critical Minerals and Materials Recovery at Domestic Industrial Facilities
$75,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Jan 15, 2026

Date Added

Nov 17, 2025

This funding opportunity provides financial support for pilot projects that recover critical minerals and materials from industrial processes in the U.S., targeting both coal-based and other industries to enhance domestic supply chain security.

Energy
Public and State controlled institutions of higher education
FY2026 Research Opportunities in Accelerator Stewardship and Accelerator Development
$3,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

May 21, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for research and development in accelerator technology, targeting academic institutions, national labs, and for-profit companies to advance innovations that benefit multiple scientific fields and enhance domestic manufacturing capabilities.

Science and Technology
Public and State controlled institutions of higher education
Advancing Health Equity through Interventions to Prevent and Address Housing Instability (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 13, 2024

Date Added

Sep 25, 2024

This funding opportunity supports U.S. research institutions and organizations in developing and testing housing interventions that improve health outcomes and reduce disparities for populations facing housing instability, particularly among older adults and marginalized communities.

Education
State governments
NIDCD Low Risk Clinical Trials in Communication Disorders (R01 Clinical Trial Required)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2025

Date Added

Oct 20, 2023

This funding opportunity supports researchers conducting low-risk clinical trials to improve understanding and treatment of communication disorders, such as hearing and speech issues.

Health
State governments
Centers for Accelerating Phage (Bacteriophage) Therapy to Combat ESKAPE Pathogens (CAPT-CEP) (P01 Clinical Trial Not Allowed)
$1,200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 28, 2025

Date Added

Oct 24, 2024

The grant title "Centers for Accelerating Phage (Bacteriophage) Therapy to Combat ESKAPE Pathogens (CAPT-CEP)" aims to fund research centers that will develop innovative tools and models to advance phage therapy against antibiotic-resistant ESKAPE pathogens, fostering collaboration between academia and industry.

Health
State governments
ROSES 2025: A.7 Water Quality Applications
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Dec 16, 2025

Date Added

Jul 12, 2025

This grant provides funding for research and technology development focused on improving water quality applications, targeting a wide range of organizations including government, private, and non-profit entities involved in environmental science.

Science and Technology
Public and State controlled institutions of higher education
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 13, 2024

Date Added

Sep 22, 2021

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligible institutions to enhance predoctoral research training of individuals seeking health professional degrees and help ensure a heterogenous pool of clinical and translational scientist trainees who are equipped with the knowledge, skills and abilities to advance diagnostics, therapeutics, clinical interventions, and behavioral modifications aimed at improving health.

Health
Small businesses
Catalytic Application Testing For Accelerated Learning Chemistries Via High-Throughput Experimentation And Modeling Efficiently (Catalchem-E)
$3,500,000
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Feb 25, 2026

Date Added

Nov 15, 2024

This funding opportunity supports multidisciplinary teams in the U.S. to accelerate the development of advanced catalysts for energy applications through high-throughput experimentation and artificial intelligence.

Opportunity Zone Benefits
Individuals
NOAA RESTORE Science Program FFO-2025: Long-term Trends
$4,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Aug 22, 2024

Date Added

Mar 27, 2024

The purpose of this document is to advise the public that the NOAA RESTORE Science Program is soliciting proposals for projects of five years in duration with the option for a five year, non-competitive renewal award for high-performing projects. This announcement invites proposals that request funding for partnerships that include researchers, resource managers, and other interested parties to conduct a collaborative research project that will identify, track, understand, or predict trends and variability in the Gulf of Mexicos natural resources and the abiotic and biotic factors driving those trends. Funding is contingent upon the availability of funds in the Gulf Coast Restoration Trust Fund. It is anticipated that final recommendations for funding under this Announcement will be made in June 2025, and that projects funded under this Announcement will have a October 1, 2025 start date. Total funding for this competition will be approximately $17.5 million over five years and approximately six projects may be funded. The minimum individual award amount is approximately $1 million over five years (an average of $200,000 per year) and the maximum individual award amount is approximately $4 million over five years (an average of $800,000 per year). An additional $21 million may be available for five year, non-competitive renewals for high performing projects. Information regarding this Announcement, including webinars and additional background information, is available on the Science Programs website (https://restoreactscienceprogram.noaa.gov/funding-opportunities/ffo-2025).The NOAA RESTORE Science Program encourages applicants and awardees to support the principles of diversity, equity, and inclusion when writing their proposals and performing their work. Promoting diversity, inclusion, and equity improves the creativity, productivity, and vitality of the research and management communities and leads to more robust natural resource management decisions.Electronic Access: The NOAA RESTORE Science Program website (http://restoreactscienceprogram.noaa.gov/) furnishes supplementary information. Full proposals should be submitted electronically through Grants.gov (http://www.grants.gov).

Natural Resources
Private institutions of higher education
Limited Competition: Continued Development of INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndromE) Project Data Coordinating Center (U2C Clinical Trial Not Allowed)
$6,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 12, 2024

Date Added

Nov 6, 2024

This funding opportunity is designed for organizations currently involved in Down syndrome research to enhance a data coordinating center that will improve health outcomes for individuals with Down syndrome by facilitating data integration and collaboration.

Health
State governments
Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations
$8,000,000
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention)
Federal

Application Deadline

Jan 26, 2022

Date Added

Oct 28, 2021

This funding opportunity provides financial support to state, territorial, and tribal organizations for cancer prevention and control initiatives, focusing on improving access to screening, building coalitions, and enhancing cancer data collection to reduce disparities and promote health equity.

Health
State governments
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
$375,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Jan 10, 2022

This funding opportunity is designed to support small-scale research projects at health professional and graduate schools that have limited NIH funding, helping to enhance research capabilities and engage students in meaningful research experiences.

Education
State governments
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2025

Date Added

Oct 31, 2024

This grant provides funding for research projects that explore the complex relationship between adolescent social media use and mental health, particularly focusing on risks, resilience factors, and the experiences of underserved youth.

Health
State governments
ITV - Industrial Technology Validation Program
$400,000
U.S. Department of Energy
Federal

Application Deadline

Jan 29, 2026

Date Added

Dec 23, 2025

This program provides funding for technology developers and industrial facilities to collaboratively test and validate innovative energy-efficient technologies in real-world industrial settings, enhancing their performance and adoption.

Energy
Small businesses
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)
$295,924
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Sep 28, 2023

This funding opportunity is designed to support small businesses in developing innovative technologies that address social needs impacting substance use disorders, with a focus on improving access to care and reducing barriers for at-risk individuals.

Education
Small businesses