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Grants for Small businesses - Federal

Explore 1,859 grant opportunities

BJA FY25 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Investigations Training and Technical Assistance (TTA)
$3,000,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

May 13, 2026

Date Added

Apr 16, 2026

This funding opportunity provides financial support to organizations that will deliver specialized training and technical assistance to law enforcement agencies nationwide, enhancing their capabilities to combat illicit drug distribution and improve public safety related to substance use.

Law Justice and Legal Services
Public and State controlled institutions of higher education
NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Nov 20, 2024

This grant provides funding to small U.S.-based businesses developing innovative technologies for heart, lung, blood, and sleep disorders, helping them bridge the gap between research and market readiness.

Health
Small businesses
Request for Information (RFI): Accelerating Speed to Power/Winning the Artificial Intelligence Race: Federal Action to Rapidly Expand Grid Capacity and Enable Electricity Demand Growth
Contact for amount
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Nov 21, 2025

Date Added

Oct 22, 2025

This initiative seeks input from energy stakeholders to identify and develop large-scale electric grid projects that can meet the increasing energy demands of industries like data centers and advanced manufacturing.

Energy
State governments
NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 - Clinical Trial Not Allowed)
$800,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 17, 2025

Date Added

Nov 1, 2024

This funding opportunity supports academic and research institutions in implementing innovative programs to improve research rigor and transparency in neuroscience, ultimately enhancing the quality and reliability of scientific findings.

Health
State governments
2026 Wood Products Infrastructure Assistance Program
$2,000,000
U.S. Department of Agriculture (Forest Service)
Federal

Application Deadline

Apr 22, 2026

Date Added

Feb 19, 2026

This funding opportunity provides financial support to various organizations for improving wood processing facilities that utilize materials from federal or Tribal land restoration projects, aiming to enhance forest health and reduce wildfire risks.

Natural Resources
State governments
Military Unique Sustainment Technology II
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Aug 2, 2025

Date Added

Mar 20, 2025

This funding opportunity is designed to support innovative research and development projects that enhance military logistics, supply chain resilience, and operational readiness for the Department of Defense.

Science and Technology
For profit organizations other than small businesses
FY26 Marine Turtle Conservation for Sustainable U.S. Fisheries Grant Program
$220,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jun 30, 2026

Date Added

Apr 30, 2026

This funding opportunity provides financial support for U.S.-based organizations and individuals to develop projects that conserve endangered marine turtle populations while promoting sustainable practices in U.S. commercial fisheries, particularly in the Pacific Islands Region.

Environment
Nonprofits
Notice of Intent to Issue Infrastructure Investment and Jobs Act (IIJA): Mines and Metals Capacity Expansion Piloting By-Product Critical Minerals and Materials Recovery at Domestic Industrial Facilities
$50,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Dec 15, 2025

Date Added

Aug 14, 2025

This funding opportunity is designed to support domestic industrial facilities in recovering critical minerals and materials from byproducts, enhancing the U.S. supply chain and reducing reliance on foreign sources.

Energy
For profit organizations other than small businesses
NIJ FY25 Research and Evaluation for the Testing and Interpretation of Physical Evidence in Publicly Funded Forensic Laboratories
$1,500,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Jun 3, 2026

Date Added

May 4, 2026

This funding opportunity provides financial support for research projects aimed at improving the testing and interpretation of physical evidence in publicly funded forensic laboratories across the United States.

Science and Technology
State governments
Microsystems Technology Office (MTO) Office-wide
$2,000,000
U.S. Department of Defense (DARPA - Microsystems Technology Office )
Federal

Application Deadline

Mar 2, 2026

Date Added

May 10, 2024

This funding opportunity supports innovative research in microsystems technology, targeting a wide range of applicants including universities, small businesses, and minority institutions, to develop advanced microelectronic systems that enhance U.S. national security.

Science and Technology
For profit organizations other than small businesses
Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Mar 9, 2024

This funding opportunity supports small businesses in the U.S. to develop innovative health solutions that improve outcomes and reduce disparities for minority populations and underserved communities.

Education
Small businesses
Cognitive Terrain Flight Model Development
$250,000
U.S. Department of Defense (DoD)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2025

This funding opportunity is designed to support small businesses in developing advanced AI and machine learning technologies that enhance the safety and effectiveness of Army aviation operations in challenging terrain.

Science and Technology
Small businesses
Infrastructure Investment and Jobs Act (IIJA): Mine of the Future - Proving Ground Initiative
$40,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Jan 30, 2026

Date Added

Nov 17, 2025

This funding opportunity provides financial support for the establishment of national-scale testing facilities for innovative mining technologies, aimed at enhancing the U.S. critical minerals supply chain through collaborative projects among academia, industry, and other stakeholders.

Natural Resources
Public and State controlled institutions of higher education
NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Jan 30, 2024

This funding opportunity provides financial support for small businesses to conduct innovative clinical trials related to allergy and infectious diseases, focusing on high-risk studies and unlicensed products.

Health
Small businesses
Community-led Monitoring of Integrated Primary Health Care Services Activity (INTEG-CLM-PHC) in Togo
$2,400,000
U.S. Agency for International Development (Ghana USAID-Accra)
Federal

Application Deadline

Not specified

Date Added

Aug 22, 2024

This grant provides funding to improve primary health care services in Togo by enhancing their quality and community responsiveness, particularly for vulnerable groups like women, children, and people living with HIV/AIDS.

Health
Individuals
Stimulate Utilization of Plentiful Energy in Rocks through High-temperature Original Technologies SBIR/STTR (SUPERHOT SBIR/STTR)
$4,505,859
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Mar 5, 2026

Date Added

Jan 29, 2026

This funding opportunity provides financial support to small businesses developing innovative technologies to harness superhot geothermal energy, aiming to create sustainable and cost-effective electricity generation systems.

Opportunity Zone Benefits
Small businesses
TechAccess: AI-Ready America
$3,000,000
U.S. National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Mar 26, 2026

This funding opportunity provides financial support to organizations in each state or territory to establish coordination hubs that enhance artificial intelligence readiness by connecting education, workforce, industry, and government stakeholders.

Science and Technology
Public and State controlled institutions of higher education
Farmers Market Promotion Program Fiscal Year 2026
$500,000
U.S. Department of Agriculture (Agricultural Marketing Service)
Federal

Application Deadline

Jun 5, 2026

Date Added

Apr 22, 2026

This grant provides funding to various organizations and businesses to promote and expand direct marketing opportunities for local agricultural products, benefiting farmers and communities across the U.S.

Agriculture
Nonprofits
Notice of Intent to Publish a Funding Opportunity Announcement: Technology Development to Reduce Health Disparities (R01 Clinical Trial Optional)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 26, 2026

Date Added

May 22, 2025

This funding opportunity provides financial support for the development of affordable and culturally appropriate biomedical technologies aimed at reducing healthcare disparities among underserved populations in the United States.

Health
State governments
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 17, 2025

Date Added

Nov 1, 2023

This funding opportunity provides financial support to U.S.-based small businesses and academic researchers for the discovery and development of small molecule drugs targeting disorders of the nervous system.

Education
Small businesses