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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

DoW Orthopaedic, Applied Research Award
$3,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 18, 2026

Date Added

May 22, 2026

This funding opportunity supports applied research projects that develop practical solutions for improving treatment and rehabilitation of orthopaedic injuries in military personnel and veterans.

Science and Technology
Nonprofits
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 2, 2025

This grant provides funding for collaborative projects between academic institutions and industry partners to develop and validate innovative technologies for disease diagnosis and treatment.

Education
State governments
Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Jan 9, 2026

This grant provides researchers access to valuable biospecimens and data from a national health initiative to conduct large-scale studies that advance precision medicine and improve understanding of health outcomes.

Science and Technology
Public and State controlled institutions of higher education
Reducing the burden of parasitic infections in the United States through evidence-based prevention and control activities.
$1,250,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCEZID)
Federal

Application Deadline

Not specified

Date Added

Dec 11, 2025

This funding opportunity provides financial support to a wide range of organizations, including state and local governments, educational institutions, and nonprofits, to implement evidence-based strategies for preventing and controlling parasitic infections across the United States.

Health
Nonprofits
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 11, 2025

This funding opportunity supports U.S. small businesses in collaboration with research institutions to develop innovative technologies that improve health outcomes through research and commercialization efforts.

Health
Small businesses
NIH Directors Early Independence Awards (DP5 Clinical Trial Optional)
$5,100,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Aug 6, 2025

This funding opportunity supports early-career researchers who have recently completed their doctoral or clinical training, allowing them to launch independent research projects without the need for preliminary data.

Health
Public and State controlled institutions of higher education
Sociology
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jan 6, 2025

This funding opportunity supports researchers in sociology to conduct innovative studies that deepen our understanding of social behavior, institutions, and structures across various topics.

Income Security and Social Services
Public and State controlled institutions of higher education
Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2026

Date Added

Jul 9, 2025

This funding opportunity provides financial support for researchers to conduct innovative analyses of existing HIV/AIDS data and specimen collections, focusing on improving health outcomes for mothers, children, and adolescents.

Health
Public and State controlled institutions of higher education
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)
$450,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 26, 2024

This grant provides funding for researchers and organizations to develop and test innovative strategies to prevent and address the effects of prenatal alcohol exposure and Fetal Alcohol Spectrum Disorders.

Health
State governments
Evaluations of Practices for Program Integrity and Fraud Prevention
$425,000
U.S. Department of Health and Human Services (Administration for Children and Families)
Federal

Application Deadline

Aug 3, 2026

Date Added

May 18, 2026

This funding opportunity provides financial support for collaborative research projects between Child Care and Development Fund Lead Agencies and qualified partners to improve program integrity and prevent fraud in child care services across the U.S.

Income Security and Social Services
State governments
Small Business Innovation Research Program (SBIR) Phase II
$287,500
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support to small businesses that have completed an initial research project, enabling them to develop innovative solutions that improve health, community living, and employment outcomes for individuals with disabilities.

Science and Technology
Small businesses
Science of Learning and Augmented Intelligence
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Aug 23, 2024

This grant provides funding for researchers exploring how people learn and enhance their cognitive abilities through technology and collaboration, with a focus on interdisciplinary studies that connect various levels of analysis.

Science and Technology
Public and State controlled institutions of higher education
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 11, 2025

This funding opportunity supports innovative research projects that explore new methods for identifying genetic causes of rare disorders, inviting a diverse range of applicants including governments, nonprofits, and businesses.

Health
State governments
Autism Centers of Excellence R01
$10,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2026

Date Added

Sep 24, 2025

This funding opportunity supports collaborative research projects focused on advancing the understanding of autism spectrum disorders through multi-site partnerships among various research institutions and organizations.

Health
Public and State controlled institutions of higher education
Forecast to Publish a Notice of Funding Opportunity for SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 17, 2025

This funding opportunity provides financial support to small businesses that have previously received federal Phase II awards, helping them advance cancer-related technologies toward commercialization through partnerships with investors.

Health
State governments
Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 6, 2024

This funding opportunity supports research projects aimed at developing innovative interventions to reduce health disparities in liver diseases and liver cancer among underserved populations in the United States.

Education
State governments
Resource and Capacity Building to Advance the Science of Aggression across Species and Disciplines (R24 Clinical Trial Optional)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 26, 2025

This funding opportunity supports the development of resources and infrastructure to improve the understanding, prevention, and treatment of aggressive behavior across various species and disciplines, targeting researchers and institutions involved in behavioral and social sciences.

Health
State governments
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 3, 2024

This grant provides funding to licensed neurologists and neurosurgeons in the NINDS intramural program to help them transition to independent faculty positions at external institutions while conducting neuroscience research.

Health
State governments
Telehealth Nutrition Services Network Grant Program
$300,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Jul 2, 2026

Date Added

May 1, 2026

This program provides funding to a variety of organizations to develop and expand telehealth networks that deliver nutrition services, aiming to improve access to healthy eating support for underserved communities across the U.S.

Health
Nonprofits
NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 3, 2025

This funding opportunity supports researchers in analyzing existing vision-related health data to develop innovative solutions for preventing and treating blindness and impaired vision in the U.S.

Health
State governments