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Grants for Small businesses - Federal

Explore 1,517 grant opportunities

Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports innovative research to identify and develop treatments for central nervous system complications in individuals living with HIV, inviting a diverse range of applicants including governments, nonprofits, and educational institutions.

Health
State governments
Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 18, 2025

This funding opportunity supports research to improve mental health care for older adults with serious mental illness by developing and evaluating effective interventions across various healthcare settings.

Health
Nonprofits
Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
Contact for amount
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 12, 2025

This funding opportunity supports clinical research aimed at developing new treatments for rare diseases, targeting a wide range of eligible organizations, including universities, nonprofits, and businesses, to address significant unmet medical needs.

Health
Public and State controlled institutions of higher education
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This funding opportunity supports researchers conducting observational studies to improve understanding and treatment of musculoskeletal, rheumatic, and skin diseases, ultimately informing future clinical trials.

Health
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports research projects that involve clinical trials to improve health outcomes, targeting a wide range of eligible applicants including universities, nonprofits, and international organizations.

Education
State governments
Spinal Cord Injury (SCI) Model Systems National Data and Statistical Center
$800,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Apr 24, 2026

Date Added

Sep 8, 2025

This funding opportunity provides financial support to a wide range of organizations, including governments, educational institutions, and nonprofits, to establish a national data center that will enhance research and improve rehabilitation outcomes for individuals with spinal cord injuries.

Science and Technology
State governments
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for researchers to study the neurobiological and behavioral mechanisms of mood and psychosis symptoms in women undergoing menopause, with the goal of developing new interventions and improving mental health outcomes.

Health
State governments
Forecast for BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 28, 2025

This funding opportunity supports specialized research projects that develop scalable technologies for mapping brain connectivity, targeting a wide range of institutions and organizations involved in neuroscience research.

Health
For profit organizations other than small businesses
PRIMED-AI: Validation Center (U54 Clinical Trial Not Allowed)
$3,900,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 1, 2026

Date Added

Jun 7, 2025

This funding opportunity supports the establishment of a center dedicated to validating AI tools that improve healthcare decision-making by integrating medical imaging with other health data, targeting a wide range of eligible organizations and institutions.

Health
County governments
Radar Signal Processing Improvements for Probability of Detection
$250,000
U.S. Department of Defense (DoD)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2025

This grant provides funding for small businesses to develop innovative radar signal processing techniques that improve detection capabilities for military applications, while also exploring potential uses in commercial sectors like drone detection and healthcare.

Science and Technology
Small businesses
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research projects that develop innovative and culturally responsive tools for measuring children's language development and identifying predictors of language impairments, with a focus on community engagement and inclusivity.

Health
State governments
AIM-AHEAD & NCATS Training Program
$10,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Not specified

Date Added

Sep 11, 2025

This program provides training and financial support for researchers from diverse backgrounds to learn how to analyze real-world clinical data using artificial intelligence and machine learning methods.

Health
Nonprofits
Magnetic Acceleration Generating New Innovations and Tactical Outcomes (MAGNITO)
$3,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Not specified

Date Added

Aug 26, 2025

This grant provides funding for innovative projects focused on developing advanced magnetic materials that exceed current performance standards, targeting a wide range of applicants including universities, nonprofits, and businesses in the U.S.

Energy
Individuals
Avant Garde/Avenir award for Investigators conducting high risk/high reward research on HIV and Substance Use (or Substance Use Disorders)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 15, 2026

Date Added

May 29, 2025

This funding opportunity supports innovative researchers tackling the complex issues of HIV and substance use disorders, encouraging high-risk, high-reward projects that could lead to significant advancements in public health.

Health
For profit organizations other than small businesses
NSF Analysis Research Program
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Mar 17, 2020

This program provides funding for researchers and institutions in mathematical analysis to support innovative studies and collaborative efforts in various mathematical fields.

Science and Technology
Public and State controlled institutions of higher education
Forecast to Publish a Funding Opportunity Announcement for Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 3, 2025

This funding opportunity supports the development of innovative informatics technologies that improve cancer research and management, targeting a wide range of eligible applicants including educational institutions, nonprofits, and small businesses.

Health
State governments
Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 9, 2025

This funding opportunity supports small-scale clinical trials aimed at improving the prevention, diagnosis, or treatment of diseases related to diabetes, digestive, and kidney health, with a focus on innovative approaches and enhancing diversity in research participation.

Food and Nutrition
State governments
Forecast to Publish a Funding Opportunity Announcement for Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 17, 2025

This funding opportunity supports research organizations conducting cancer epidemiology cohort studies to investigate cancer causes and survivorship, with a focus on maintaining existing cohorts and sharing biospecimens and data.

Health
For profit organizations other than small businesses
Notice of Intent to Publish a Funding Opportunity Announcement for Single Source for Continuation of the Integrated Islet Distribution Program (UC4)
$3,300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 13, 2025

This funding opportunity provides financial support for organizations involved in diabetes research to continue the distribution of human islets, which are vital for advancing scientific understanding and developing new treatments for diabetes.

Health
City or township governments
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 22, 2024

This funding opportunity supports researchers using unique pre-diagnostic biospecimens from the PLCO Biorepository to advance cancer understanding and develop early detection biomarkers.

Education
State governments