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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

Notice of Intent to Publish a Funding Opportunity Announcement for HIV Pediatric, Adolescent and Maternal Clinical Trials
$30,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 26, 2025

This funding opportunity supports clinical trials focused on HIV in children, adolescents, and mothers, encouraging innovative research collaborations among a wide range of eligible organizations.

Health
State governments
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 8, 2024

This funding opportunity supports research projects that enhance digital mental health interventions to improve outcomes for individuals, particularly those facing health disparities, through partnerships between software developers and academic researchers.

Health
State governments
Rural Community Health Support Program
$4,500,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2026

This funding opportunity provides financial support to a wide range of organizations working to improve healthcare access and services for underserved populations in rural communities across the United States.

Health
Public housing authorities
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 19, 2025

This program provides funding to U.S.-based small businesses with prior NIH Phase II or IIB awards to help them advance their biomedical innovations toward commercialization through activities like clinical trials and regulatory preparation.

Health
Small businesses
Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research
$2,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Sep 13, 2025

This funding opportunity supports collaborative research initiatives in neuroscience and mental health, aimed at understanding and addressing the mechanisms underlying mental disorders, and is open to a wide range of organizations, including nonprofits, educational institutions, and government agencies.

Health
State governments
Disability and Rehabilitation Research Projects (DRRP) Program: Employment Among People Who Are Deaf or Hard of Hearing
$700,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Apr 23, 2026

This funding opportunity provides financial support for research projects aimed at improving employment outcomes for individuals who are deaf or hard of hearing, focusing on evidence-based practices that enhance job participation, retention, and career advancement.

Science and Technology
State governments
Rural Northern Border Region Network Planning Program
$100,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Apr 8, 2026

This funding opportunity provides financial support to various organizations in Maine, New Hampshire, New York, and Vermont to develop or strengthen collaborative healthcare networks that improve access and quality of care for underserved rural populations.

Health
Nonprofits
Pregnancy and Postpartum Hypertension Control Initiative
$550,000
U.S. Department of Health & Human Services (Office of the Assistant Secretary for Health)
Federal

Application Deadline

Not specified

Date Added

Aug 2, 2024

This funding opportunity provides financial support to a variety of organizations working to implement self-measured blood pressure practices for pregnant and postpartum individuals in underserved and rural communities, aiming to improve maternal health outcomes.

Health
City or township governments
Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 12, 2025

This funding opportunity supports new and early-stage researchers in developing innovative projects that combine engineering and physical sciences with biomedical research to improve human health.

Health
State governments
Autism Centers of Excellence P50
$10,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2026

Date Added

Sep 24, 2025

This funding opportunity supports innovative research projects aimed at advancing the understanding of autism spectrum disorder, inviting diverse organizations and researchers to collaborate on interdisciplinary studies.

Health
State governments
Digital Cities Innovation Accelerator Small Grant Program
$700,000
U.S. Department of State (Bureau of Cyberspace and Digital Policy)
Federal

Application Deadline

Not specified

Date Added

Feb 19, 2026

This funding opportunity supports U.S. and foreign organizations in implementing innovative digital technologies to improve municipal services and infrastructure in urban areas across Latin America and the Caribbean.

Science and Technology
Nonprofits
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 4, 2025

This funding opportunity provides financial support for researchers to investigate the ethical, legal, and social implications of human genetic and genomic research, encouraging innovative studies that address emerging issues in the field.

Education
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports a wide range of research projects aimed at advancing medical knowledge and improving health, available to various organizations including universities, nonprofits, and businesses.

Education
State governments
Field Initiated Projects Program (Research)
$250,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support for research projects that aim to improve the lives of individuals with disabilities by enhancing their inclusion, independence, and employment opportunities.

Science and Technology
State governments
Ryan White HIV/AIDS Program Part D Coordinated HIV Services and Access to Research for Women, Infants, Children, and Youth (WICY) Existing Geographic Service Areas
$2,000,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Dec 22, 2025

This funding opportunity provides financial support to organizations delivering coordinated, family-centered HIV care for low-income women, infants, children, and youth affected by HIV in designated geographic areas.

Health
Nonprofits
NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 13, 2025

This funding opportunity supports audiologists pursuing a Ph.D. by providing mentorship and resources for their dissertation research in areas related to hearing, balance, speech, and language disorders.

Health
State governments
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for innovative research projects that use invasive techniques to study brain activity related to mental health disorders, targeting researchers and institutions focused on advancing our understanding of neural circuitry and its impact on behavior and emotions.

Health
State governments
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports innovative research projects that explore the underlying mechanisms of neuropsychiatric symptoms in individuals with Alzheimer's disease, aiming to improve understanding and treatment of these symptoms.

Health
State governments
HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Clinical Trial Center and Clinical Centers (U01 Clinical Trial Optional)
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 9, 2026

Date Added

Sep 3, 2025

This funding opportunity provides financial support for academic institutions, nonprofit organizations, and other eligible entities to establish clinical trial centers focused on advancing research and treatment for heart failure with preserved ejection fraction through coordinated clinical trials and patient engagement.

Health
Public and State controlled institutions of higher education
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 4, 2025

This funding opportunity supports organizations in developing and implementing innovative interventions to improve cancer screening and preventive services for populations facing health disparities.

Education
State governments