Grants for Special district governments - Federal

This funding opportunity provides financial support for institutions and organizations to create and manage a resource that supplies human tissues and organs for biomedical research, benefiting studies on various diseases and health conditions.

This funding opportunity announcement (FOA) is a reissue due to an omission of TRAINING RECORD review questions in Section V. This FOA encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low-and middle-income countries (LMICs, as defined by the World Bank classification system). Applications may be for collaborations between institutions in the U.S and an eligible LMIC or may involve just LMIC institutions if there is a previous track record of externally funded research and/or research training programs by the lead LMIC institution. The proposed institutional research training program is expected to sustainably strengthen the NCD research capacity of the LMIC institutions, and to train in-country experts to develop and conduct research on NCDs across the lifespan, with the long-range goal of developing and implementing evidence-based interventions relevant to their countries. The main focus of research training covered in the application must be relevant to the interests of at least one of the participating NIH ICs as stated by each in this FOA. Other NCD topics may be included as secondary and complementary focus areas. This Funding Opportunity Announcement (FOA) allows support of trainees as the lead investigator of an independent clinical trial; or a separate ancillary study to an existing trial; or to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The "Mechanisms of Inducing HIV Immunity in Early Life (MIEL)" grant is a funding opportunity that supports research aimed at understanding and developing methods to establish and maintain immunity against HIV in children from birth to less than 12 years old, with a focus on the use of vaccines and antibodies, and the influence of maternal factors and vaccine adjuvants.

This funding opportunity supports researchers exploring the ethical, legal, and social issues related to human genetic and genomic research, particularly as these technologies become more integrated into healthcare and society.

This program provides funding to organizations and local governments to build broadband networks in rural areas lacking internet access, promoting economic development, education, and healthcare.

The purpose of this Funding Opportunity Announcement (FOA) is to correlate immune system development patterns between two or more age groups - neonates, infants, and children and adolescents and further understand the impact of infectious diseases, microbiome and environmental factors on the ontogeny and development of the pediatric immune system, from birth, transitioning into adolescence and adulthood with the focus of impact during pregnancy and post-natal period.Purpose The purpose of this Funding Opportunity Announcement (FOA) is to correlate immune system in general and development patterns in particular, between two or more age groups - neonates, infants, and children and adolescents and further understand the impact of infectious diseases, microbiome and environmental factors on the ontogeny and development of the pediatric immune system, from birth, transitioning into adolescence and adulthood with the focus of impact during pregnancy and post-natal period. Background Worldwide, mortality in children under the age of 5 is predominantly due to infectious diseases and immune modulations associated with these infections. Pediatric immune system is remarkably different from adult immune system and also forms the basis for overall wellbeing and providing an adequate disease encountering status to adulthood. A protected and systematically trained pediatric immune system results in a robust and efficient adult immune system. Moreover, immune system in children responds strongly, rapidly and robustly in comparison to adult immune system to immunization, diet and environmental factors. Knowledge of development of the pediatric immune system in response to exposure to childhood infections and vaccinations, microbiome and the environmental factors can help chart pathways that provide strategies to prevent and treat infectious diseases more efficiently. These variations between pediatric and adult immune systems offer insight into better understanding strategies for developing immune-therapeutics and vaccines against infections. The research focus in the current announcement is multi-disciplinary. The focus however is in the areas of immune ontogeny and development, the mechanisms of infant and neonatal immunity or relationship between ontogeny of immunosuppression, susceptibility to infection during infancy or studies on effect of early infections or vaccinations that train the immune system. It is expected to diversify areas in existing research and draw comparisons between age groups or specific organ system development (for example, projects of interest might investigate immune cell ontogeny in lung alveoli from infancy to adult hood or immune alterations due to exposure to a specific immunogen (like measles or BCG vaccine) at infancy vs adolescence and the chronic effect of air pollution). More specifically, the aim here is to elucidate immune system development patterns in infants, children and adolescents focusing on both the innate immunity and the development of diverse antibodies or T cell maturation, with relevance to chronic infections (not limited to HIV, CMV, TB and the current SARS-CoV2 pandemic as well). Further, the intention is to expand the science to include additional internal factors like microbial metabolites and/or external factors like the environment that modulate the developing immune system so that a research program that is multi-disciplinary can be developed to address the interaction between host and pathogen. Research Scope The over-arching scope of this FOA is: to correlate immune system in general and development patterns in particular, between two or more age groups - neonates, infants, and children and adolescents to understand the evolution or immune ontogeny in human immune system development focusing on either or both, innate and adaptive immune systems with additional focus on internal factors like the microbiome and/or external factors like the environment. Further, the scope can be covered under these following topics and is not limited to: Study in young children vs adolescents vs adults, development of immunity and variations in immune system in physiology and in response to infectious diseases focusing on MTCT diseases (HIV, CMV, TB, Syphilis, SARS-CoV2 etc.), not limited to, broadly neutralizing antibodies (bNAbs), development of mucosal antibodies, germinal center formation and maturation; correlate with T cell development and identification of immunogens that activate T cells without enhancing infection. Characterize the impact of age, environmental factors, microbial metabolites and microbiome composition in relation to the immune responses against acute or chronic infectious diseases not limited to HIV, TB, CMV, SARS-CoV2 etc., and their contribution towards the development of a robust immune system development using novel technologies (RNA seq, imaging of immunogens and cellular interactions, single cell imaging). Understand cellular and soluble immune system components and the developmental pathways, including the microbiome, that regulate these components in specific age-groups. For example, developing immune profiles of HIV exposed un-infected (HEU) infants in comparison with the immune profile of an adolescent living with HIV and how these immune alterations prepare the immune system to encounter future infections. Study the contribution of increased exposure to environmental factors, pathogens, extensive or scheduled immunization early in life on enhanced cross-talk between innate and adaptive immune systems; specific inflammatory responses generated by innate immune factors and their downstream effect on cellular immune development. Delineate the role of human microbiome in health and disease and the environmental factors to observe correlation of immune responses against acute and chronic infections and focus on transfer of microbes and immune factors from human milk to infants. For example, assess alterations in immune profiles of known oral microbial clusters in CMV infected child vs immune profiles in an adolescent. Understand the impact of variations of microbiome in specific organ systems (gut vs oral vs vaginal microbiomes) in age defined profiles and their effect on immune ontogeny with emphasis on Virome . Influence of maternal microbiome on the effect of microbial composition and development of immunity in the offspring; detailed studies exploring placental microbiome and correlation with maternal oral microbial microbiome are encouraged. Projects that will be considered non-responsive for this FOA include, but are not limited to: Applications proposing vaccine advocacy. Applications proposing to focus exclusively on effects of microbiome and not studying the relevance of these effects on immune system development. Applications proposing to focus exclusively on epigenomic approaches. Applications focusing on immunization strategies in infants for altering early immune responses.

This grant provides funding for research projects aimed at improving the diagnosis and treatment of health conditions related to the September 11, 2001, terrorist attacks, specifically for individuals who were exposed in New York City and surrounding areas.

This funding opportunity provides financial support to states and organizations for developing a coordinated care model that improves health services for children with serious, long-term medical conditions.

This grant provides funding to strengthen the management and evaluation of human resources in Malawi's national HIV and TB programs, focusing on hiring skilled personnel to support epidemic control efforts.

Through this cooperative agreement, the Office of Head Start (OHS) within the Administration for Children and Families (ACF) will make available the funds to enhance coordination and collaboration between the Office of Head Start (OHS) Region XII Office, the OHS Training and Technical Assistance system, Head Start recipients, other providers of early care and education, and stakeholders that provide services related to the development and learning of low-income migrant and seasonal worker children and families. The Collaboration office will promote partnerships with child care that emphasize the Early Head Start-Child Care Partnership Initiatives; collect data regarding early childhood programs and child outcomes; support the expansion and access of high quality workforce and career development opportunities for staff; work with school systems to ensure continuity between Head Start and school system goals; and, support other regional office priorities such as family and community partnerships; and, health, mental health, and oral health.

This grant provides funding to early-stage researchers exploring innovative chemical and pharmacological approaches to understanding and treating substance use disorders.

This funding opportunity provides financial support to U.S. states and territories for innovative projects that improve safety and efficiency in commercial motor vehicle operations through advanced technology and data systems.

The STRIPE program grant is designed to fund pre-clinical research that explores how radiopharmaceutical therapy affects cancer cells and their environment, with the aim of developing new targeting strategies and informing the design of future RPT-based clinical trials.

This funding opportunity supports innovative interventions to improve the health and quality of life for people living with HIV, particularly those from racial and ethnic minority populations and low-income backgrounds, by addressing related health issues and promoting successful aging.

This funding opportunity supports innovative research projects aimed at improving mental health services and addressing disparities in access and quality, particularly for underserved populations.

Federal Awarding Agency Name: U.S. Department of Agriculture (USDA), Natural Resources Conservation Service (NRCS), Commodity Credit Corporation (CCC) Funding Opportunity Title: Regional Conservation Partnership Program (RCPP) Classic for Federal fiscal year (FY) 2024 Funding Opportunity Number: USDA-NRCS-NHQ-RCPP-24-NOFO0001354 Assistance Listing: 10.932, Regional Conservation Partnership Program (RCPP) Due Date: NRCS must receive proposals by 4:59 p.m. Eastern Time on July 12, 2024. Note: The RCPP Classic and Alternative Funding Arrangement (AFA) FY 2024 notices of funding opportunity (NFO) will run concurrently. For information on AFA proposals please see Funding Opportunity Number USDA-NRCS-NHQ-RCPPAFA-24-NOFO0001355. The RCPP promotes the coordination of NRCS conservation activities with partners that offer value-added contributions to expand our ability to address on-farm, watershed, and regional natural resource concerns. Through the RCPP, NRCS seeks to co-invest with partners to implement projects that provide solutions to conservation challenges thereby measurably improving the resource concerns they seek to address. RCPP promotes collaboration with partners, stakeholders, and various communities, which is paramount to achieving equity in NRCS programs and services. Using guidance contained in this notice, partners propose projects that generate conservation benefits by addressing specific natural resource concerns in a state or multistate area by addressing one or more priority resource concerns within an NRCS-designated critical conservation area (CCA). NRCS and partners collaborate to design, promote, and implement RCPP projects on agricultural and nonindustrial private forest land. Through RCPP, NRCS may provide both financial assistance (FA) and technical assistance (TA) funds to project partners and agricultural producers for implementing projects. RCPP proposals are evaluated through a competitive proposal process based on three criteria: impact, partner contributions, and partnership and management. Up to $1.5 billion is available for RCPP projects through this announcement and the FY 2024 AFA announcement, which includes $300 million of the Agriculture Improvement Act of 2018 (2018 Farm Bill) funding and $1.2 billion of Inflation Reduction Act (IRA) funding. Proposals are accepted from all 50 States, the Caribbean Area (Puerto Rico and the U.S. Virgin Islands), and U.S. territories in the Pacific Island Areas (Guam, American Samoa, and the Commonwealth of the Northern Mariana Islands). NRCS will prioritize using IRA funds for projects that will implement climate-smart agriculture and forestry conservation activities as described in section F.(3)a. of this announcement. Up to $100 million is being made available specifically for NRCS to enter into programmatic partnership agreements with Indian tribes. This set aside will be shared by this announcement and the FY 2024 AFA announcement. Any unused funds may be available for other partnership agreements. Submissions: Proposals must be submitted through the RCPP portal. See section E of this announcement for information on using the RCPP portal to submit proposals. Access to the RCPP portal requires a level 2 eAuthentication credential or a Login.gov credential. Obtaining a new Login.gov credential involves multiple steps and can take several days to complete. Instructions are posted on the How to Apply to RCPP web page listed below. For More Information: Applicants are expected to contact the appropriate State Conservationists and state RCPP coordinators prior to submitting a proposal. NRCS will use a state conservation questionnaire to record the results of this conversation. Proposals without a completed questionnaire may have their score and ranking reduced. A list of state RCPP coordinators (as of the date of this announcements posting) is on the NRCS How to Apply to RCPP web page. Applicants can also email the RCPP inbox (rcpp@usda.gov) with any questions about the announcement. The RCPP website is also a great source of current information about the program. Interested applicants are encouraged to participate in one or more of the webinars below to learn about the program and how to apply. 2024 RCPP NFO Applicant Outreach Webinar This webinar will provide general information for applicants submitting proposals for the Regional Conservation Partnership Program (RCPP). The same material will be covered at both webinars followed by a question-and-answer section. Please refer to the RCPP website for more information. Regional Conservation Partnership Program Natural Resources Conservation Service (usda.gov) April 23, 2024, RCPP Applicant Outreach Webinar Registration Link 2pm to 4pm EDT - https://events.gcc.teams.microsoft.com/event/e2f45f75-7ea4-410b-b1c9-567537cd2454@ed5b36e7-01ee-4ebc-867e-e03cfa0d4697 May 30, 2024, RCPP Applicant Outreach Webinar Registration Link 2pm to 4pm EDT - https://events.gcc.teams.microsoft.com/event/226dcb51-0b57-43b1-b340-95e535238713@ed5b36e7-01ee-4ebc-867e-e03cfa0d4697 NRCS will schedule additional webinars on RCPP easements and providing outreach to tribal applicants. Information on all webinars will be posted to the RCPP how to apply page.

This funding opportunity supports projects that strengthen U.S.-U.K. relations through public diplomacy initiatives, targeting a range of organizations and individuals focused on democracy, global challenges, and cultural exchange.

This funding opportunity provides financial support for researchers and institutions to discover and develop new treatments for serious fungal infections that are difficult to treat due to resistance and safety issues.

The 2024 States’ Economic Development Assistance Program (SEDAP), announced by the Delta Regional Authority (DRA), seeks applications for grants to target federal resources toward communities in the Mississippi River Delta and Alabama Black Belt regions. With a focus on economically distressed counties and parishes, SEDAP aims to invest in community-based and regional projects across four congressionally mandated funding categories: basic public infrastructure, transportation infrastructure, business development with an emphasis on entrepreneurship, and workforce development. The program is designed to encourage job creation, regional collaboration, and funding partnerships, leveraging a total of $16,930,642, allocated across the eight-state DRA region with awards ranging from $50,000 to $500,000 depending on project type and application score.

This funding opportunity provides financial support to state and local governments for improving forensic science and medical examiner services, focusing on reducing case backlogs, enhancing training, and addressing challenges related to the opioid crisis.