Federal Science and Technology Grants

This funding opportunity supports research projects that improve forensic science practices in publicly funded laboratories, targeting advancements in areas like DNA testing and toxicology, and is open to a range of eligible applicants including government entities and educational institutions.

To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. Agency Overview: The Advanced Research Projects Agency Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): (A) to enhance the economic and energy security of the United States through the development of energy technologies that (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies. ARPA-E issues this Funding Opportunity Announcement (FOA) under its authorizing statute codified at 42 U.S.C. 16538. The FOA and any cooperative agreements or grants made under this FOA are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established learning curves where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. In contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development. The Office of Management and Budget defines applied research as an original investigation undertaken in order to acquire new knowledgedirected primarily towards a specific practical aim or objective and defines experimental development as creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes. Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts) should contact the DOEs Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). Program Overview: The Technologies to Emend and Obviate Synthetic Nitrogens Toll on Emissions (TEOSYNTE) program aims to lower nitrous oxide (N2O) emissions from the cultivation of corn and sorghum used for United States (U.S.) ethanol production by 50%. The program will emphasize plant and microbial bio-design strategies that lower the application of synthetic nitrogen (N) fertilizer on corn and sorghum fields while maintaining crop yields and reducing 50% of N2O emissions. Lowering the requirements of synthetic N fertilizer will also lower costs to farmers, as the cost of fertilizer is a significant portion of the operating expenses of a farm. This program will enable technologies to reduce N fertilizer consumption and N2O emissions. These technologies will transform agriculture and lower the N2O contribution to the carbon intensity of ethanol produced today for light duty vehicles and in the future for sustainable aviation fuel. Technologies developed under the TEOSYNTE program must achieve specific targets as outlined in Section I.E. in order to meet the programs objectives to reduce greenhouse gas (GHG) emissions and N fertilizer usage over multiple seasons while maintaining crop yields. To view the FOA in its entirety, please visit https://arpa-e-foa.energy.gov.

This is a Request for Information (RFI) only. This RFI is not accepting applications for financial assistance. The purpose of this RFI is solely to solicit input for ARPA-E consideration to inform the possible formulation of future programs. The purpose of this Request for Information (RFI) is to solicit input for a potential ARPA-E program focused on leveraging material, process, equipment, and cross-supply chain manufacturing innovations to catalyze domestic production of cathode active materials (CAMs) and their precursors (pCAMs). Most commercial lithium-ion batteries employ graphite anodes and layered transition metal oxide cathodes. CAMs can account for approximately 50% of total battery cost, while CAM chemistry determines overall battery performance and safety.5 To date, commercial cell-level energy densities exceeding 280 watt-hour per kilogram (Wh/kg) are achievable in batteries where NMC is used as the CAM in combination with a graphite anode.6 Recent optimization efforts have focused on innovations in chemistry to decrease cobalt content and increase nickel content thus simultaneously increasing energy density and reducing cost. Moreover, significant government and private sector research funding has been allocated to develop alternative lithium-based battery chemistries. Thus far, LFP is the most commercially successful nickel-free and cobalt-free cathode to be developed with notable attributes in cost, safety, and cycle life. Recent gains in market share suggest that LFP batteries may become the dominant chemistry for compact, economy EVs, while NMC is likely to continue to be the preferred cathode chemistry for vehicles where torque response and range are priorities. To view the RFI in its entirety, please visit https://arpa-e-foa.energy.gov.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to identify and optimize novel molecules that exhibit inhibitory effects on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated proteins (CRISPR-Cas) gene editing processes. The Broad-Spectrum Antagonists for Editors (B-SAFE) program is explicitly seeking transformative approaches enabling the discovery or design of novel inhibitors of gene editing technologies with enhanced activity, utility, and breadth of coverage. Novel inhibitor activity will be assessed in vitro over the course of the program and a subset of top performing molecules will be selected for scale-up at quantities sufficient for testing and evaluation by Department of Defense (DoD) stakeholders. In concert, DARPA is interested in exploring methods to rapidly discover inhibitor molecules for novel gene editing technologies beyond CRISPR-Cas systems to keep pace with the rapidly advancing field and promote the safe, controlled use of these technologies. Research that generates incremental improvements to the existing state-of-the-art are specifically excluded.

This funding opportunity is designed for researchers and organizations focused on advancing ocean science and technology to enhance national security, economic development, and environmental protection.

This funding opportunity provides financial support for researchers and organizations focused on studying earthquake hazards and developing safety measures to mitigate risks associated with seismic events in the U.S.

This funding opportunity provides financial support for projects that develop innovative strategies and tools to improve employment outcomes for individuals with disabilities, focusing on inclusive practices and diverse populations.

Please note that this program requests optional Notices of Intent, which are due via NSPIRES by April 26, 2024. See the full posting on NSPIRES for details. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

The Water Resources Development Act (WRDA) of 2000 authorized the Comprehensive Everglades Restoration Plan (CERP) as a framework for modifications and operational changes to the Central and Southern Florida Project needed to restore the south Florida ecosystem. Provisions within WRDA 2000 provided for specific authorization for an adaptive assessment and monitoring program. The CEPP is a CERP project expected to provide an additional 370,000 acre-feet of freshwater to the Everglades annually. Freshwater fishes and invertebrates play a critical role at the base of the food chain within Everglades marshes, providing food to iconic apex predators like wading birds and alligators. Changes in water quantity and quality that influence freshwater fish and invertebrate assemblage structure directly influences wading bird ecology and ecosystem integrity of Everglades marshes. Monitoring of fishes and large invertebrates is necessary to track changes in water management associated with restoration projects both within Everglades National Park and upstream within the Water Conservation Areas. Long-term monitoring data are required to support assessment of the changes in water management. This project will conduct field sample collection, process samples, and data analyses and evaluate the long-term data set with regards to natural resource condition assessments. The CEPP Adaptive Management and Ecological Monitoring Plans identify the freshwater fish and macroinvertebrate communities as essential attributes of the ecosystem that need to be monitored to assess the influence of the CEPP and to confirm additional freshwater is improving the production and availability of aquatic fauna (fish and macroinvertebrates) to support higher tropic levels. This monitoring of aquatic fauna will inform CEPP Adaptive Management actions associated with CEPP performance in conjunction with other CERP projects and non-CERP operations. Program Description/Objective: (brief description of the anticipated work) The purpose of this research is to leverage a long-term dataset to monitor the status and trends of freshwater fish and macroinvertebrate populations at established sites within Water Conservation Area 3 (WCA3) in order to determine pre-CEPP implementation baseline conditions for aquatic fauna to inform CEPP Adaptive Management and Ecological Monitoring Plans The project objectives include: Objective 1: Collect samples to monitor status and trends of large (>8cm) and small (<8cm) freshwater fish and macroinvertebrate populations at 10-12 established sites in WCA3 up to 5 times intra-annually. Objective 2: Establish and report the baseline condition of aquatic faunal abundances and biomasses for future use in a Before, After, Control, Impact (BACI) assessment of CEPP project implementation. Objective 3: Demonstrate progress and present results in the form of quarterly status reports, annual reports, and a final report. Public Benefit This project will play a critical role in determining the effect of the CEPP on the aquatic fauna community in WCA3 and continue to build upon the knowledge base for understanding the ecology of the freshwater trophic community in the Greater Everglades ecosystem. Data collected will be used to inform the successful implementation of the CEPP and support the CERP in reaching its restoration goals and objectives. Understanding aquatic faunal dynamics within WCA3 is critical to assess and the effects of hydrologic changes associated with CEPP implementation, ecosystem restoration, and climate change which have potential impacts on the economy of South Florida, including tourism, recreational opportunities, and water management.

This funding opportunity provides financial support for the development of a collaborative data framework that enhances data sharing and innovation among agricultural stakeholders, including universities, producers, and nonprofit organizations across the U.S.

This program provides funding for early-career scientists to conduct innovative research in polar science while promoting diversity and collaboration within the field.

The NSF Ocean Observatories Initiative (OOI) is a community-inspired and community-serving large scale research facility enabling ocean science research. It consists of an integrated network of instrumentation arrays, distributed in various coastal and global ocean locations that collect, archive, and distribute quality oceanic and marine atmospheric data to the ocean and Earth science communities. NSF has established the NSF Ocean Observatories Initiative Facility Board (OOIFB) to engage the user community through workshops, community meetings, and other interactive mechanisms to provide the NSF OOI and the NSF with a better understanding of the current and future community needs as they relate to the scientific and technological innovation that the OOI supports. This solicitation invites proposals for an Administrative Support Office to support the OOIFB in carrying out its responsibilities. The Support Office is responsible for organization of meetings and workshops, coordination and support for travel for OOIFB members and workshop participants, maintenance of the OOIFB website, as well as other activities described within the Program Description section of this solicitation.

Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

The DoD Arthritis, Focused Research Award is a funding opportunity aimed at supporting innovative, high-risk/high-reward arthritis research that could lead to significant discoveries or improvements in patient care and quality of life, with a particular emphasis on the impact of arthritis in the military and on women's health.

The surge in online media usage has surged within recent years, especially within Africa where a growing portion of the population happens to be young adults who have come to find digital technology at the forefront of their everyday lives. Because of its substantial importance in day-to-day life, theres now a major interest in ensuring security, safety, and responsible use within online mediums of communication. A. PROGRAM DESCRIPTION The U.S. Embassy Dar es Salaam / Bureau of African Affairs of the U.S. Department of State announces an open competition for organizations to submit applications to carry out a program to create targeted exchange programs and a conference aimed at relevant Tanzanian policymakers, civil servants, and civil society to explore internet governance structures and strategies that promote a free and open internet governance policy in Tanzania to catalyze the expansion of the local digital economy and lead to economic growth. Please follow all instructions below. Program Objectives: This opportunity seeks to directly engage a Tanzanian civil society organization to identify a cohort of colleagues across a range of sectors, engage the cohort through multiple education and information sessions, and organize a major international conference on the theme of building resilient, open, and democratic digital systems. The conference should include U.S. experts who can advise on regulatory firewalls, policy creation and coordination, and balancing the protection of individual rights, general online safety and security with freedom of expression principles. The selected organization should have demonstrated familiarity with Tanzanias civic space and policy processes. This opportunity also seeks to provide international exchange opportunities where Tanzanian thought leaders can engage with counterparts in international fora such as the UN Internet Governance Forum and/or with American counterparts. Through these engagements, the program will help to build an ecosystem of Tanzanian innovators and champions of democracy who can effectively advocate as citizens and government civil servants to contribute to an economic growth friendly digital infrastructure. Challenges that should be addressed by proposals: Boosting civic participation and engagement Addressing the limited access to accurate and verified information in rural and underserved communities and offered in local languages. Tackling the lack of media literacy to help individuals discern credible sources of information and leveraging digital tools and platforms to build resiliency. Examine the government’s efforts to manage cybersecurity risk and assess threats to critical infrastructure. Reducing and overcoming cultural divides by promoting accessible digital literacy resources and training programs to Tanzanian communities. Providing opportunities for open discussions and exchanges for tech leaders and policy makers in a variety of fields to prepare Tanzania to be an international partner in tech innovation. Discuss efforts to secure an open interoperable secure and reliable cyberspace in accordance with U.S. security standards. Discuss strategies to collaborate and counter cyber threats. Participants and Audiences: Tech industry stakeholders, STEM students, policymakers, social media influencers/reporters, and academic experts. B. FEDERAL AWARD INFORMATION Length of performance period: 6 to 24 months Number of awards anticipated: 2 awards (dependent on amounts) Award amounts: awards may range from a minimum of $75,000 to a maximum of $425,000 Total available funding: $495,000 Type of Funding: FY23 Economic Support Funds under the Foreign Assistance Act Anticipated program start date: 10/01/2024 This notice is subject to availability of funding.

The "Earth and Environmental Systems Science in the Southeast U.S." grant aims to fund collaborative research that enhances understanding and modeling of ecosystems, atmospheric processes, and regional phenomena in the Southeast U.S., with a focus on vegetation, land-atmosphere interactions, spatial heterogeneity, convection, clouds, precipitation, biogenic aerosols, and extreme events.

To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. Agency Overview: The Advanced Research Projects Agency Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): (A) to enhance the economic and energy security of the United States through the development of energy technologies that (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies. ARPA-E issues this Funding Opportunity Announcement (FOA) under its authorizing statute codified at 42 U.S.C. 16538. The FOA and any cooperative agreements or grants made under this FOA are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established learning curves where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. In contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development. The Office of Management and Budget defines applied research as an original investigation undertaken in order to acquire new knowledgedirected primarily towards a specific practical aim or objective and defines experimental development as creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes. Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts)1 should contact the DOEs Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). Program Overview: The Nuclear Energy Waste Transmutation Optimized Now (NEWTON) program will support the research and development of technologies that enable the transmutation of used nuclear fuel (UNF) to alleviate the impact of storage in permanent disposal facilities. This program seeks to fund the development of novel technologies that increase the overall capacity factor, power output, and efficiency of particle generation systems (including but not limited to proton, neutron, and/or photon), by reducing beam trip magnitude and duration (referred to as loss of beam). Additional technologies will focus on increasing the throughput of transmutation by developing target materials that maximize transmutation rates and are easily processible to remove the transmuted material. The United States does not currently have an active facility for the permanent disposal of used nuclear fuel derived from the civilian nuclear sector. Used nuclear fuel comprises several classes of isotopes that could be processed in different ways due to their economic value. Firstly, uranium (U), which comprises greater than 95% of the mass of UNF, can be reprocessed and converted back into fuel for light-water reactors through the addition of small amounts of uranium-235 (U-235). Secondly, plutonium (Pu) and minor actinides (MAs), such as neptunium (Np), americium (Am), and curium (Cm), which together comprise roughly 1.5% of UNF by mass, are produced from nuclear fission. Many of these isotopes are fissionable and could be incorporated into fuels designed for advanced reactor concepts. Intermediate-lived fission products (ILFPs) including strontium-90 (Sr-90) and caesium-137 (Cs-137) have relatively short half-lives of roughly 30 years and have applications in radioisotope thermoelectric generators for space applications. However, ILFPs are largely destined for permanent disposal in a deep geological repository. The major long-lived fission products (LLFPs) have half-lives exceeding 200,000 years and have few commercial applications. LLFPS include selenium-79 (Se-79), technetium-99 (Tc-99), tin-126 (Sn-126), iodine-129 (I-129), and caesium-135 (Cs-135). The last class of isotopes are the stable isotopes produced from nuclear fission and resulting decay. These isotopes could be extracted from UNF, but no commercial processing of these have been undertaken. A deep geological disposal facility for the disposition of UNF in the U.S. has been estimated to cost $96.18 billion over the 150-year lifetime, after which the facility would cease to accept new waste. This facility would be able to store 70,000 metric tons (MT) of unprocessed UNF, which is insufficient for the existing volume of civilian waste. Densification of the waste can be accomplished through removal of the plutonium, minor actinides, and ILFP components of the UNF. Removal of 99.9% of these components would allow a densification factor of 225, based on current disposal requirements, thus allowing a single repository to store upwards of approximately 16 million MT of UNF. The LLFPs are responsible for many of the engineered barriers that are required to be built in the repository due to their long half-lives and environmental mobility. Removal of these LLFPs could decrease the capital expenditure of a permanent geological repository while also improving safety. To view the FOA in its entirety, please visit https://arpa-e-foa.energy.gov.

This grant provides funding for eligible organizations to conduct an archaeological survey and documentation of cultural resources at Florissant Fossil Beds National Monument in Colorado, enhancing historical preservation efforts and educational opportunities.

This funding opportunity provides financial support to research institutions in underrepresented jurisdictions to collaborate with NASA on aerospace research projects that address specific needs identified by the agency.

The LRP IPA encourages applications that support the full spectrum of research projects or ideas that specifically focus on scientific and clinical lupus issues, which, if successfully addressed, have the potential to make a major impact in lupus research and/or lupus disease. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale that is established through inferential reasoning and/or critical review and analysis of the literature. Inclusion of preliminary data is encouraged.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health.