Federal Science and Technology Grants

This grant provides funding to organizations focused on improving the humanitarian data ecosystem by developing workforce skills and establishing data technology standards to enhance crisis response efforts.

This funding opportunity provides a portion of the annual catch limit of Atlantic sea scallops to various eligible organizations and individuals for research projects that enhance scientific understanding and management of the scallop fishery.

The DoD Kidney Cancer, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that have the potential to significantly impact the treatment or management of kidney cancer, with a focus on new products, pharmacologic agents, devices, clinical guidance, and emerging approaches and technologies.

This funding opportunity supports collaborative research projects in energy-related fields by institutions in underfunded U.S. jurisdictions, with a focus on building research capacity and promoting student involvement.

This initiative provides $52.5 million in cash awards to teams developing innovative technologies for capturing carbon dioxide from the atmosphere, with a focus on promoting environmental equity and community benefits.

This funding opportunity is designed to support citizen science projects that enhance federal fisheries stock assessments and improve understanding of climate change impacts on fish stocks and fishing communities.

With a focus on enhancing research capacity and broadening participation of new faculty of biology at minority-serving institutions (MSIs), predominantly undergraduate institutions (PUIs), and other universities and colleges that are not among the nations most research-intensive institutions, the Directorate for Biological Sciences (BIO) offers theBuilding Research Capacity of New Faculty in Biology(BRC-BIO) program. The BRC-BIO program aims to a) broaden participation by expanding the types of institutions that submit proposals to BIO, and b) expand opportunities to groups underrepresented in the biological sciences, including Blacks and African Americans, Hispanics, Latinos, Native Americans, Alaska Natives, Native Hawaiians and other Pacific Islanders, and persons with disabilities, especially those serving at under-resourced institutions. Awards will provide the means for new faculty to initiate and build independent research programs by enhancing their research capacity. These projects might also include biology-focused research collaborations among faculty within the same institution, across peer-, or research-intensive institutions, or partnerships with industry or other non-academic partners that advance the candidates research program. By providing this funding opportunity, BIO recognizes the national urgency to broaden, strengthen, and diversify the science, technology, engineering, and mathematics (STEM) workforce. In particular, these awards will build capacity for research at institutions that have a primary focus on teaching and undergraduate education, or that have limited capacity for research. Projects should enable the establishment of sustainable research programs for faculty and also enrich undergraduate research experiences and thereby grow the STEM workforce. BRC-BIO welcomes proposals from principal investigators who share NSF's commitment to diversity, equity, and inclusion. Proposals in response to this solicitation must be submitted to the Division of Biological Infrastructure (DBI) in the Directorate for Biological Sciences (BIO).

This funding opportunity provides financial support for research projects focused on improving ecological restoration practices in the Colorado Plateau region, particularly in response to climate change and soil water challenges.

This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSOs interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.Aspects of todays health and public health systems remain fragile due to systemic challenges, which include rising healthcare costs, inadequate healthcare coverage for significant populations, outdated infrastructure, and health disparities among different demographic groups. Acute challenges, such as hospital closures, supply chain disruptions, staffing shortages, cyber-attacks, public health crises, and the emergence of new diseases, further exacerbate existing fragilities, making it more difficult to maintain high standards of care. These challenges are compounded by the fact that systems remain fragmented, hindering the ability to gain comprehensive insights, make informed decisions, develop tailored interventions, and share critical health information between stakeholders.RSO seeks solution summaries and proposals that drive innovations to enhance the adaptability, reliability, and interoperability of the health ecosystem. Of interest are innovations that foster flexibility and enable adaptation to system stressors, so that people and systems remain well-positioned to deliver high-quality care and improve health outcomes. The following interest areas categorize the ground-breaking research we seek to support:Sociotechnical System Innovation: Innovate user-centric digital health tools, platforms, technologies, and intervention models that improve outcomes across the health continuum, including prevention, diagnosis, and treatment of physical, mental, and behavioral health. Approaches to build trust in the healthcare system and distribute high-quality health guidance in an understandable manner that improves patient outcomes. Novel real-time measurement tools to track health outcomes, evaluate post-market performance of new interventions, and enable convergence on the most effective strategies to improve the quality of care, especially for underserved communities. Other population centered innovations to create more resilient communities and subpopulations. Innovations might include aggregate improvements to quality of care and better physical, mental, and behavioral health outcomes for the health ecosystem.Health Ecosystem Integration: Novel ways to collect, protect, secure, integrate, analyze, communicate, and present health data, including but not limited to advances in privacy, cyber security, artificial intelligence with enhanced patient safety properties, low-code or no-code technologies, semantic approaches, and rapid integration techniques. Strategies and technologies to leverage homes, community centers, pharmacies, and other accessible locations to enable new modalities of high-quality care, expand the reach of clinical research, or integrate end-user feedback to rapidly iterate prototype designs. Approaches to strengthen the connectivity and interoperability of health data and devices to 5 enable the safe, secure, and seamless exchange of information among healthcare providers, researchers, and stakeholders. Other novel approaches to increase the interoperability of health-related systems in support of improved health outcomes and enhanced transparency across the health ecosystem.Adaptive Antifragile Solutions: Creative approaches to enhance the stability and dependability of the health ecosystem through new adaptive paradigms, methods that anticipate and mitigate disruptions before they occur, and enhancements to emergency response. Approaches that enable health infrastructure to rapidly integrate information from new sensors; create decision support tools; adapt supply chains, manufacturing, and logistics; and better leverage the workforce during public health emergencies. Novel methods to engineer resilient tissues, microbiomes, and biophysical systems to combat disease or maintain health. Other novel approaches to enhance adaptability and reduce fragility within the health ecosystem.Proposals are expected to use innovative approaches to enable revolutionary advances in science, technology, systems, or methodology. Specifically excluded are proposals that represent an evolutionary or incremental advance in the state of the art or technology that has reached the clinical trial stage. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission

The following objective summarizes the work for a maximum of three (3) unique, stand-alone projects. Over the life of the cooperative agreement (3 years), it is anticipated that 3 projects would be completed. Objective 1: Investigator will collaborate with ERDC researchers to develop laboratory or mesocosm and protocols and conduct experiments to determine herbicide efficacy for the operational chemical management of European frogbit. Any needed permitting should be obtained prior to collecting laboratory or mesocosm protocols. Objective 2: Collect mesocosm and field data on chemical control efficacy within managed vs non-managed European frogbit sites. These data should include but are not limited to: percent change in plant abundance following chemical management, biomass and turion production, and comparison of these data between managed vs. non-managed sites. Any needed permitting should be obtained prior to collecting mesocosm of field data. Objective 3: Develop herbicide management guidance based on most up to date frogbit management research. All data shall be incorporated in a report using peer-review publication format. Status and draft reports shall be submitted for ERDC review on a quarterly basis.

This funding opportunity provides financial support for research on oyster pads and wave trip systems to improve coastal resilience and habitat restoration in the Houston Ship Channel, specifically targeting academic and research partners within designated Cooperative Ecosystem Study Units.

Artificial Intelligence (AI) has advanced tremendously and today promisespersonalizedhealthcare; enhanced national security; improved transportation; and more effective education, to name just a few benefits. Increased computing power, the availability of large datasets and streaming data, and algorithmic advances in machine learning (ML) have made it possible for AI research and development to create new sectors of the economy and revitalize industries. Continued advancement, enabled bysustainedfederal investment and channeled toward issues of national importance, holds the potentialfor further economic impact and quality-of-life improvements. The 2023 update to theNational Artificial Intelligence Research and Development Strategic Plan,informed byvisioning activities in the scientific communityas well asinteraction with the public, identifies as its first strategic objective the need to make long-term investments in AI research in areas with the potential for long-term payoffs in AI. AI Institutes represent a cornerstone Federal Government commitment to fostering long-term, fundamental research in AI while also delivering significantly on each of the other eight objectives in that strategy. The National Security Commission on Artificial Intelligence (NSCAI) identifies AI Institutes as a key component of a bold, sustained federal push to scale and coordinate federal AI R funding and to reinforce the foundation of technical leadership in AI. This program is a multisector effort led by the National Science Foundation (NSF), in partnership with the Simons Foundation (SF), the National Institute of Standards and Technology (NIST), Department of Defense (DOD) Office of the Under Secretary of Defense for Research and Engineering (OUSD (R)), Capital One Financial Corporation (Capital One),and Intel Corporation (Intel). This program solicitation expands the nationwide network of AI Research Institutes with new funding opportunities over the next two years.In this round, the program invites proposals for institutes that have a principal focus in one of the following themes aimed at transformational advances in a range of economic sectors, and science and engineering fields: Group 1 - Awards anticipated in FY 2024: Theme 1: AI for Astronomical Sciences Group 2 - Awards anticipated in FY 2025: Theme 2: AI for Discovery in Materials Research Theme 3: Strengthening AI For the institute themes listed in Group 1, NSF anticipates awards to start in FY 2024; and forthemes listed in Group 2, NSF anticipates awards to start in FY 2025. Each group has a specific set of due dates and review timeline pertaining only to that group. Moredetail is found under Due Dates and in the timeline provided in the Program Description.

The MMRDA mechanism is intended to fund the logical continuation of previously DOD-funded research or development efforts relevant to the above FY24 JWMRP Focus Areas with the highest potential to augment and accelerate medical product development and health care solutions for active-duty Service Members, their Families, Veterans, and/or the American public. Collaboration with DOD organizations is encouraged when this alliance would contribute to the success of the research effort, and any funds designated for DOD laboratories or activities should be identified in the application/proposal through submission of a Suggested Intragovernmental/Intramural Budget Form, Attachment 15. Applications/proposals from small businesses and/or partnerships with industry are also encouraged. The MMRDA mechanism supports a wide range of research projects, spanning late-stage preclinical studies, late-state technology development efforts, technology demonstration, and translational research. A Clinical Research or Clinical Trial Option is available to specifically support clinical research/observational studies, all phases of clinical trials/interventional studies, and/or correlative studies in support of the development of promising pharmaceutical or biologic candidates, medical devices, and technologies. Note: Applications/proposals submitted under this option will be required to submit additional relevant application/proposal materials.

This Funding Opportunity Announcement (FOA) describes a newly proposed initiative of the Air Force Research Laboratory (AFRL) concerning standing up a University Center of Excellence (CoE) for Data Assimilation (DA) Driven by Mathematical Features Representing Physics with educational institutions in the United States. The University CoE is defined as a joint effort among multiple technical directorates (TDs) of the Air Force Research Laboratory to include: the Air Force Office of Scientific Research (AFOSR), Aerospace Systems Directorate (RQ), Space Vehicles Directorate (RV), and Munitions Directorate (RW), referred to collectively as we, our, or us, in this FOA, and an outstanding university or team of universities that will perform high priority unclassified and collaborative basic / applied (6.1/ 6.2) research which addresses the United States Air Force (USAF) and United States Space Force (USSF) research needs in the DA area with relevance to high-speed flows and combustion.

This funding opportunity is designed for research institutions affiliated with the Great Rivers Cooperative Ecosystem Studies Unit to investigate floodplain forest dynamics and regeneration in the Upper Mississippi River System.

This funding opportunity provides financial support for innovative breast cancer research projects aimed at preventing the disease, understanding its recurrence, or improving treatment, targeting both early-stage and more developed studies from a range of eligible organizations and researchers.

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

This grant provides funding for collaborative clinical trials aimed at improving the diagnosis and treatment of health issues related to military toxic exposures, targeting researchers and institutions involved in this critical area of study.

This funding opportunity provides financial support for research organizations in California to develop and assess biological control methods for managing the invasive giant cane, which threatens local ecosystems and water resources.

This funding opportunity provides financial support for research and data collection projects focused on geological structures, public lands classification, and natural resources, aimed at federal, state, tribal, and academic partners.