Grants for For Profit Organizations Other Than Small Businesses

This funding opportunity is designed for U.S.-based research institutions to advance the measurement of exoplanet masses, enhancing our understanding of their characteristics and formation processes.

The purpose of this program is to strengthen the behavioral health workforce in rural Northern Border Regional Commission (NBRC) service areas through supporting the recruitment and retention of behavioral health care providers.

This funding opportunity provides financial support to organizations that aim to strengthen the capacity and collaboration of State Offices of Rural Health and improve healthcare services in rural communities across the United States.

The DoD Kidney Cancer, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that have the potential to significantly impact the treatment or management of kidney cancer, with a focus on new products, pharmacologic agents, devices, clinical guidance, and emerging approaches and technologies.

This grant provides $4,250 to support U.S.-based women and minority entrepreneurs in growing their businesses through funding, resources, and mentorship.

This initiative provides $10,000 grants to over 100 LGBTQ small businesses in the U.S. that are owned by and serve LGBTQ people of color, women, and the transgender community, particularly those facing financial challenges due to COVID-19.

The Opelousas Downtown Development District (ODDD), with support from the City of Opelousas and Opelousas Main Street (OMS), is launching the fifth round of funding for its Building Improvement Grant (BIG) program. This program is a grant/reimbursement initiative designed to empower property and business owners in rehabilitating commercial buildings. The overarching mission alignment for this program is to create a positive visual impact within the city, stimulate private investment, and diligently preserve Opelousas' historic identity and cultural assets. The primary beneficiaries of this grant program are property and business owners within the Opelousas Downtown Development District who own commercial buildings. The core impact goals are to foster economic development through private investment, enhance the aesthetic appeal of the downtown area, and ensure the safeguarding of the city's rich historical and cultural heritage. The program directly supports the revitalization of commercial spaces, which, in turn, contributes to a more vibrant and economically robust downtown. The program's priorities and focuses are clearly on tangible and permanent building improvements. Eligible uses of funds are comprehensive, including restoration and renovation of buildings, installation of awnings (without signage), brick cleaning or re-pointing, accent lighting, removal of deteriorating or inappropriate materials visible from the street, and restoration of windows, doors, and original exterior/interior architectural features. Additionally, interior work related to ceiling repair, electrical, and plumbing is covered, as well as work on roofs, cornices, gutters, downspouts, and the cleaning, preparation, and painting of walls and trim. These priorities are aimed at holistic improvement of commercial properties. The expected outcomes include a noticeable improvement in the visual appeal of downtown Opelousas, an increase in private investment in commercial properties, and the successful preservation of historic buildings. While not explicitly stated as "measurable results" in the traditional sense, the program's structure and goals imply that the number of rehabilitated buildings, the amount of private investment stimulated, and the visible improvements in the downtown area would serve as key indicators of success. The program offers a total of $200,000 in grant funds, with a maximum application amount of $10,000 per project, providing a clear framework for financial allocation and impact tracking.

The DoD Kidney Cancer, Academy of Kidney Cancer Investigators - Early-Career Scholar Award is a grant aimed at supporting early-career scholars in conducting kidney cancer research, providing them with funding, networking, and collaborative opportunities, and mentorship for a period of four years, with the ultimate goal of advancing kidney cancer research and developing highly productive kidney cancer researchers.

This program provides $10,000 in funding and mentorship to Black and Brown female-identifying beauty brand founders in the U.S. with annual revenues between $10,000 and $1 million, helping them grow their businesses and potentially reach new markets.

This program recognizes and rewards innovative small and mid-sized businesses in the U.S. with cash prizes and valuable resources to enhance their growth and community impact.

The DoD Kidney Cancer, Idea Development Award is a funding opportunity aimed at supporting innovative, high-impact kidney cancer research projects, with a focus on scientific rationale, preliminary data, innovation, and potential impact, and encourages collaborations among academia, industry, military services, and other federal agencies, with a budget not exceeding $800,000 for individual projects and $1.2M for partnered projects.

With this solicitation, BJA seeks to support the families of fallen and catastrophically injured law enforcement officers, firefighters, and other first responders by providing assistance with filing applications for federal benefits for line-of-duty deaths and catastrophic injuries. This program also provides survivor peer support, counseling services, and resources to survivors of fallen law enforcement officers, firefighters, and other first responders nationwide. Additionally, the program recognizes families and fallen officers at memorial events.

This grant provides financial support to small businesses with 1-50 employees that are Xero subscribers, encouraging innovative projects in sustainability, community connection, technology, and workforce upskilling.

This grant provides funding for evaluators to assess and improve the EMS Corp program's implementation and effectiveness, drawing comparisons to the successful Alameda EMS model, with the goal of enhancing emergency medical services in the community.

The U.S. Embassy Dushanbe, Tajikistan announces an open competition opportunity to implement the English Without Borders (EWB) project in Tajikistan. The EWB project has a number of components and objectives highlighted in this funding opportunity to support English teachers through (1) providing professional development and peer- to- peer engagement and networking; (2) equipping secondary school teachers with modern teaching methodologies, and (3) utilizing the newly designed and published English textbooks. The implementer must be a legally recognized non-governmental organization, that meets U.S. and Tajikistan technical and legal requirements to develop and implement Public Diplomacy Programs as specified in Section C. Background: English Without Borders (EWB) is a project funded by the U.S. Embassy in Tajikistan and implemented since 2021, providing support to English teachers across all regions in Tajikistan. The current EWB project will conclude December 2024; this year PDS seeks to consolidate some English Language Programs under one umbrellanamely continuing EWB networking-type activities, but also providing more targeted support for secondary school (high school) English teachers to use modern teaching methods as well as the new English language textbook. EWB unites English language teachers and students at all levels, supporting them through peer-to-peer networking, the development of pedagogical materials, online and in-person training sessions, and train-the-trainer programs. These online and in-person activities develop teachers capacity to employ modern, student-centric methodologies and design supplementary materials. The U.S. Embassy in Dushanbe has an ambitious slate of English language projects, many in cooperation with the Ministry of Education and Science. These efforts support Tajikistans strategy on improving English language learning by 2030 and President Rahmons 2024 statement on learning foreign languages, including English. While the number of students interested in learning English is on the rise, the number of teachers qualified and prepared to teach them is not. This is due to the relatively sudden increase in the number of classes offered, the relatively recent emergence of English as a foreign language -- resulting in few professional teachers with a specialization in English -- and an insufficient number of English teachers. U.S. Embassy English language programs range from secondary school teacher training programs and providing English language textbooks to English Access Scholarship programs and supporting universities with English Resource Centers and English Language Fellows. In its new iteration, EWB should continue to complement and expand their collaboration with other PDS-funded projects and their participants. Due to the demand for the U.S. Embassy Dushanbes English language programs, the EWB network should continue to utilize its platforms to reach teachers across the country. EWB should continue to expand its partnership with other governmental, non-governmental, private, and international organizations to support a sustainable network for English teachers and students and provide access to learning resources, including collaboration with TESOL International Association, the English-Speaking Nation Project in Uzbekistan, and English Teachers Associations in Dushanbe and across Central Asia. The expected date range for implementation of project is December 1, 2024, to December 1, 2026. Please follow the instructions below for the application. Project Goal: Develop a network of English language educators and educational institutions across Tajikistan to deliver high-quality and effective English language instruction. Project Audience(s): Direct Audience Approximately 4,000 secondary school English teachers of Tajikistan Teachers at higher education institutions teaching in English (English language and other subjects) Tajikistan English Teachers Association members USG English-language program alumni (Fulbright TEA, FLTA, ETM, OPEN online course, SUSI, Access Scholarship programs) Institute of Professional Development members EWB members Project Objectives: Objectives: Objective 1: Increase participation of English language educators from educational institutions, particularly secondary schools, in rural areas of the DRS, Gorno-Badakhshan, Khatlon, and Sughd regions by 10% each year. Objective 2: Increase the ability of secondary school teachers from rural areas (DRS, Gorno Badakhshan, Khatlon, Sughd regions) to use modern teaching methods with the new English language textbook through comprehensive training conducted by EWB regional trainers and mini grants. Objective 3: Increase the number of EWB initiatives implemented at schools, universities and institutions, and local communities in urban and rural areas through .... Objective 4: Increase knowledge sharing between USG English language program alumni and non-alumni English language educators through mentorship programs. Objective 5: Strengthen collaboration and knowledge sharing practices between English teacher associations and English teacher networks in Central Asian countries, including Tajikistan, Kyrgyz Republic, Kazakhstan, Uzbekistan and Turkmenistan. Objective 6: Identify avenues for collaboration with the Ministry of Education and Sciences Institute of Professional Development (IPD), such as joint research, curriculum, or teacher training programs. Activities: Hold an annual leadership development program to support proactive English teachers in the regions to take on new initiatives and cooperate with the EWB regional representatives in promoting EWB activities at schools and in local communities. Create a team of EWB leaders/ambassadors in each of the four regions to hold weekly professional development and capacity building events and organize annual regional meetings. Strengthen the community of USG English language alumni in the regions (Fulbright TEA, FLTA, ETM, OPEN online course, SUSI, FLEX, Access Scholarship programs) and develop mentorship programs in each region to engage the alumni in different EWB activities and events, and to act as mentors to other (non-alumni) English teachers. Sustain dynamic work and explore new avenues for collaboration with the Institute of Professional Development (IPD) under the Ministry of Education and Science. Strengthen and expand upon our partnership with English teacher associations and English teachers networks in Central Asian countries through national and international online collaborative events and activities. Train teachers to use the new English language textbooks, for example through the EWB regional trainers activities and EWB mini grant.

The Walter F. Goodnough Trust offers grants specifically designed to support the rehabilitation of underprivileged disabled children, aligning its mission directly with improving the health and well-being of this vulnerable population. This core grant program focuses on a critical area of need within the healthcare sector for children facing both disability and financial hardship. The foundation supports this mission by funding hospitalization-based rehabilitation services exclusively within the state of Florida. The primary beneficiaries of this grant program are underprivileged disabled children in Florida who require hospitalization for rehabilitation. The overarching impact goal is to facilitate their recovery and improve their quality of life by providing essential financial support for necessary medical interventions. To achieve this, the trust prioritizes health-related programs and aims to ensure that eligible organizations, specifically 501(c)(3) exempt organizations, can access funding to serve these children effectively. Regarding expected outcomes and measurable results, the document notes that specific detailed metrics are not explicitly stated beyond the goal of "rehabilitation." However, the implicit outcome is an improvement in health and functional abilities for the children served. Success would likely be measured internally by proxies such as the number of children assisted, the types of rehabilitation services provided, and potentially the duration or effectiveness of their hospitalization and subsequent recovery. The foundation’s financial support is focused, with an average grant size ranging from $2,500 to $5,000 and an average total giving of $15,000 per year, suggesting a focus on supporting individual or smaller-scale rehabilitation projects. The foundation's strategic priorities are centered on creating a direct and measurable impact within Florida's healthcare landscape, particularly for disabled children. This focused approach is highlighted by the geographic limitation to Florida and the specific program area of Health. The trust's theory of change posits that by providing financial grants directly to qualified organizations, they can enable access to crucial rehabilitation services that would otherwise be out of reach for underprivileged families, thereby addressing a core financial barrier to recovery and improved quality of life.

This funding opportunity is designed to support U.S. organizations with limited NIH funding to conduct innovative research on the ethical, legal, and social implications of advancements in human genetics and genomics, while fostering collaboration with affected communities and developing research capacity.

The grant titled "Phased Multi-Site Clinical Trial: Testing Prevention of Cardiovascular Disease in Young Adults With High Lifetime Risk Using Surrogate Outcomes - Data Coordinating Center (Collaborative U24 Trial Required)" is aimed at funding the development and implementation of a Data Coordinating Center to manage data, provide statistical support, and ensure overall coordination for a multi-site clinical trial focused on preventing cardiovascular disease in young adults at high risk, while also promoting community engagement, diversity, and health equity.

To advance the field of patient-centered clinical decision support through research that tests tools and resources in real-world settings. The mission of the Agency for Healthcare Research and Quality (AHRQ) is to produce evidence to make healthcare safer, higher quality, and more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure the evidence is understood and used. The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research on patient-centered clinical decision support (PC CDS), a nascent area within the larger field of CDS. Through the AHRQ-funded Patient Centered Outcomes Research (PCOR) CDS Initiative and the CDS Innovation Collaborative specifically, PC CDS resources are now publicly available for interested researchers to further build upon, develop, and test, in real-world settings. Innovative research is needed to understand how to make traditional, clinician-facing CDS more patient-centered, while also engaging patients, families, and caregivers in a co-design process to design and implement these tools. BACKGROUND Clinical decision support refers to digital tools that are used to help inform patient care. Patient-centered clinical decision support (PC CDS), in contrast to traditional clinician-facing CDS, is CDS that focuses on the patient, or their caregiver, and facilitates their active involvement in healthcare decision-making with their clinicians. PC CDS uses information from patient-centered outcomes research findings and/or patient-specific information and has the potential to be transformative by enabling higher-quality care delivery and improved outcomes. PC CDS can also support shared decision making (SDM), which AHRQ defines as a collaborative process in which patients and clinicians work together to make healthcare decisions informed by evidence, the care team's knowledge and experience, and the patient's values, goals, preferences, and circumstances. PC CDS can also support shared care planning enabling patients, caregivers, and clinicians to work together to tailor a clinical plan to align with a given patients priorities and goals. PC CDS is a developing field and has the potential to increase the quality and experience of patient care. AHRQ’s CDS Initiative is supported by the Patient Centered Outcomes Research Trust Fund (PCOR TF) and is guided by AHRQ’s PCOR TF strategic framework (https://www.ahrq.gov/pcor/strategic-framework/index.html). Since 2016, AHRQ’s PCOR CDS Initiative has been building tools, concepts, frameworks, and conducting pilot projects. Much of AHRQ’s recent effort has focused on patient-centered CDS, and several past projects have generated resources that could be highly useful to the developing PC CDS field. Examples of these projects include AHRQ’s PC CDS Learning Network and CDS Connect, as well as a project that assessed the current state and future directions with PC CDS. Additional information for CDS projects is available on the PCOR CDS Initiative webpage. AHRQ’s most recent PC CDS project, the CDS Innovation Collaborative, or CDSiC, is a multi-component stakeholder-driven initiative that produced a rich set of resources and tested concepts around different aspects of PC CDS. As part of the CDSiC, four workgroups were formed, each around a specific area of PC CDS, with the charge to create products (e.g., frameworks, guides, checklists) that could be used in the clinical field to establish or measure use of PC CDS. These products could address clinical workflows or the development of CDS technologies, among other areas related to PC CDS. During the first two years of the CDSiC, these workgroups created numerous products that addressed PC CDS in different areas. These areas included CDS outcomes, trust and patient-centeredness, and scaling and dissemination. One workgroup also focused on the existing standards and regulatory frameworks that could impact the future uptake and use of PC CDS. Applicants can examine, using these products and tools, how PC CDS can support shared decision making and care planning among individuals with complex needs including older adults, people living with multiple chronic conditions, frailty, disabilities, and/or socioeconomic disadvantage and how this may foster the delivery of person-centered care. They may also study strategies to scale and spread effective tools including use in lower resourced and safety net instituions. Applicants responding to this NOFO must propose to use the resources developed by AHRQ's PCOR CDS Initiative, or any of the many products developed by the ongoing CDSiC, to further explore their usefulness, impact, and practical application in real-world settings. For example, CDSiC products that could be used may include the Taxonomy of Patient Preferences, Integration of Patient-Centered CDS into Shared Decision Making, Approaches to Measuring Patient-Centered CDS Workflow and Lifeflow Impacts, or the PC CDS Performance Measurement Inventory User Guide. Links to and descriptions of the products are available on the CDSiC Stakeholder Center webpage (https://cdsic.ahrq.gov/cdsic/cdsic-stakeholder-community-outreach-center ) The CDSiC's Innovation Center (https://cdsic.ahrq.gov/cdsic/innovation-center) developed a comprehensive report around measurement of PC CDS and created two pilot dashboards that can help clinicians understand and use Patient Generated Health Data. Additional information on other PCOR CDS projects is available at https://cds.ahrq.gov/about. Examples of Highly Responsive Projects include: A community hospital with a large priority population, selects from the CDSiC portfolio of projects generated by the Trust and Patient-Centeredness workgroup. The recipient selects the source credibility product from the Trust and Patient Centeredness workgroup and conducts a study to understand how their population perceives the information they receive from within their existing electronic health record (EHR) system. Patients provide input, and the approach is assessed against existing CDS tools, as well as the definition of PC CDS as defined by the CDSiC, to assess their level of patient-centeredness. A small startup company is developing applications (apps) to help patients improve their healthcare. The startup leverages two products from the CDSiC standards and regulatory frameworks workgroup: Advancing Standardized Representations for Patient Preferences to Support Patient-Centered Clinical Decision Support and an Environmental Scan that reveals opportunities to evolve standards and regulatory frameworks to advance PC CDS. The company works with a patient advocacy organization to co-design the patient-facing PC CDS app, uses standards to leverage existing patient generated health data (PGHD), and incorporates a final assessment as to the level of patient-centeredness of their technology. A primary care physician group is working to reduce clinician burnout with the goal of improving patient outcomes. The group looks at the CDSiC’s Taxonomy of Patient Preferences and assesses how they can incorporate these concepts into restructured workflows. The group then also uses CDSiC’s product called Approaches to Patient-Centered CDS Workflow and Lifeflow Impact, which provides a framework to help identify the optimal point for a patient-centered CDS tool’s deployment in a patient’s lifeflow. Their study will also assess how increased patient-centeredness in their CDS tools do not inadvertently have a negative impact on clinician workflows or experience. All projects are encouraged to: Incorporate Clinical Quality Language (CQL) and other HL7 standards into their project design, if appropriate for developing, integrating, (or modifying) their CDS with their EHR system or other health information technology (Health IT) components to become more patient-centered. OBJECTIVES AND SCOPE This NOFO aims to support innovative collaborative research to understand how clinical decision support tools in real-world settings can be improved to become more patient centered. Recipients will become part of an existing community of researchers who have an interest in PC CDS including AHRQ, the CDSiC, and other researchers. Interested applicants may include health information technology experts, patient advocates and representatives, clinicians, electronic health record developers, policymakers, payors, as well as leaders from research and academic medical institutions. All projects must: Utilize one or more of the products from the CDSiC or the PCOR CDS Initiative, which are available on the project website: cdsic.ahrq.gov, or another resource available from the PCOR CDS Initiative (cds.ahrq.gov), which includes the PC CDS Learning Network, CDS Connect, or AHRQ's Evaluation project that assessed the current state and future directions with PC CDS; If CDSiC products are used specifically, applicants must identify if any other frameworks are being used to evaluate the performance of their PC CDS (e.g., RE-AIM or other); Apply the definition of patient-centered CDS (available here: https://cdsic.ahrq.gov/cdsic/patient-centered-clinical-cds-infographic) and describe the degree to which each of the 4 elements are incorporated into the patient-centered CDS tool: knowledge, patient data, delivery, and use. Apply an equity lens, consistent with AHRQ's PCOR Strategic Framework. Apply at least 1 of the 4 priorities from AHRQ's PCOR Strategic Framework. Include meaningful and substantial participation from patients and/or patient representatives in the co-design, implementation, and evaluation of their research, to also be reflected in the proposed budget. Fully describe their research ecosystem. If developing or extending a digital tool, be mobile friendly to be more accessible to a broader population (for example, a patient-facing portal, website, etc.). If the research or tool will be incorporated into an EHR system, the facility must have a mature, functioning EHR system (e.g., the facility is not planning any significant system upgrade or migration). Otherwise, an alternative means to test and evaluate the selected CDS product can be described. If the research strategy intends to modify an existing clinical workflow that is currently clinician-focused, to become a patient-centric or patient-facing approach, then the strategy must include an evaluation component to characterize the performance of the PC CDS tool versus the previous clinician-facing workflow. If the proposed project plans to promote implementation of SDM, it should align with AHRQ’s definition of SDM (available here: https://www.ahrq.gov/sdm/about/index.html) and include at least one validated measure of SDM in its evaluation.

The "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II" grant aims to expand the existing mental health research network to include larger studies, provide guidance to the scientific community, and support career development for researchers from low-resource settings worldwide.