Grants for For Profit Organizations Other Than Small Businesses

This program provides matching funds to Michigan municipalities and nonprofits for community-driven projects that enhance public spaces, promoting local engagement and inclusivity.

The DoD Traumatic Brain Injury and Psychological Health, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that can significantly impact psychological health conditions and/or traumatic brain injury through the development of healthcare products, technologies, or practice guidelines.

Maturing research ideas into clinical practice and patient benefit is at the heart of all CDMRP research programs. Despite significant investment, the gap between what is possible and what is achieved remains. Even after information, tools, and interventions have been successfully evaluated in their intended populations, the development of knowledge to support their broader dissemination and implementation has often remained outside the scope. The FY24 TBIPHRP HSRA intends to bridge the gap between research, practice, and policy by building real-world evidence on how interventions, clinical practices/guidelines, and policies can be deployed to targeted populations at the appropriate time.Research Scope: The FY24 HSRA will fund clinical research (including clinical trials). Preclinical and animal research are prohibited. Prospective or retrospective clinical research or clinical trials involving human subjects, human subject data/records, and human anatomical substances are allowed. Proposed clinical trials should include interventions, clinical practices/guidelines, and policies that are well-supported within the literature and in relevant patient population(s). This award may not be used to support studies requiring an exception from informed consent (EFIC).Key aspects of the FY24 TBIPHRP HSRA: Precision Medicine Approaches: When appropriate, the TBIPHRP encourages the use of precision medicine approaches. These tailored treatments deliver the right treatment at the right time while considering an individuals unique characteristics. Community-Based Participatory Research: The application must include Community-Based Participatory Research (CBPR) approaches in the development and execution of the clinical research/trial. CBPR approaches should be documented in Attachment 8. Preliminary data are required: Inclusion of preliminary data relevant to the proposed clinical research/trial is required. Untested novel interventions are discouraged: Novel interventions that have not been evaluated in the intended population(s) are discouraged. Applicants seeking funding for novel interventions should consider one of the other FY24 TBIPHRP announcements. Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical trial appropriate to the objectives of the study. Studies utilizing human biospecimens or datasets that cannot be linked to a specific individual, gender, ethnicity, or race (typically classified as exempt from Inquiry Review Board [IRB] review) are exempt from this requirement. Clinical Trial Start Date: If applicable, the proposed clinical trial is expected to begin no later than 6 months after the award date. Intervention Availability: If applicable, the application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study.The FY24 HSRA applications may include (not all inclusive): Research that accelerates the uptake and implementation of evidence-based research into clinical practice. Comparative effectiveness research comparing the benefits and harms of emerging or established interventions and strategies to prevent, diagnose, treat, and monitor health conditions in real-world settings. Development and evaluation of strategies to overcome barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, tools, policies, and guidelines. Analysis of existing data or resources to inform clinical practice. Modification of established clinical tools for their intended population or environment. Analysis of existing clinical tools to maximize patient-relevant outcomes. Identification and analysis of the circumstances that create a need to stop or reduce (de-implement) the use of interventions, tools, policies, and guidelines that are ineffective, unproven, low-value, or harmful are within scope. Analysis of TBI and/or psychological health outcomes associated with the implementation of clinical practice guidelines, evidence-based practices, and process improvements.Early-Career Investigator Partnering Option: The FY24 TBIPHRP HSRA includes an Early-Career Investigator Partnering Option that is structured to accommodate two Principal Investigators (PIs), one of whom is an Early-Career Investigator. The combined direct costs budgeted for the entire period of performance in the applications of the Initiating PI and Partnering PI should not exceed $2.5M. The PIs may have experience in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application. One PI will be identified as the Initiating PI and will be responsible for most of the administrative tasks associated with application submission. The other investigator will be the Partnering PI. At least one of the Initiating or Partnering PIs must be an Early-Career Investigator. The intent is not to create mentor-mentee arrangement. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application is expected to describe how the PIs unique experience/expertise combined as a partnership will better address the research question, how the unique experience/expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. If recommended for funding, each PI will be named to an individual award within the recipient organization(s). For individual FY24 TBIPHRP HSRA submission requirements for the Initiating and Partnering PI, refer to S Section II.D.2, Content and Form of the Application Submission.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials. For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document.pdf.Clinical trials may be designed to evaluate pharmacologic agents (drugs or biologics), diagnostics, devices, therapies, clinical guidance, behavioral interventions, emerging approaches and technologies, and/or new indications for products currently U.S. Food and Drug Administration (FDA)-approved or -cleared. Interventions that are not FDA-regulated (or international equivalent) are within scope but the regulatory status must be documented in Attachment 12, Regulatory Strategy.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.Multi-Institutional Clinical Research/Trials: As of January 20, 2020, U.S. institutions engaged in non-exempt cooperative research must rely on a single IRB to review and approve the portion of the research conducted at domestic sites (45 CFR 46.114(b)). If the proposed, non-exempt research involves more than one U.S.-based institution, a written plan for single IRB review arrangements must be provided at the time of application submission or award negotiation. The lead institution responsible for developing the master protocol and master consent form should be identified and should be the single point of contact for regulatory submissions and requirements.Communication and data transfer between or among the collaborating institutions, as well as how specimens and/or imaging products obtained during the study will be handled, should be included in the appropriate sections of the application. A separate intellectual and material property plan agreed on by all participating institutions is also required for multi-institutional clinical research/trials.Relevance to Military Health: Relevance to the health care needs of Service Members, their Families, and Veterans is a key feature of this award. Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health: Explanation of how the project addresses an aspect of psychological health conditions and/or TBI that has direct relevance to the health and/or readiness of Service Members, their Families, and Veterans. Description of how the knowledge, information, products, or technologies gained from the proposed research could be implemented in a dual-use capacity to benefit the civilian population and also address a military need. Use of military or Veteran populations, samples, or datasets in the proposed research, if appropriate.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $15.5M to fund approximately four HSRA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity supports international collaborations to improve the detection and response to biological threats, particularly in developing countries, by enhancing biosurveillance and biosecurity capabilities.

To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that is more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.

The Administration for Children and Families (ACF), Office of Head Start (OHS) announces the availability of approximately $14 million to be competitively awarded for the purpose of expanding access to high-quality, comprehensive services to Migrant and Seasonal infants, toddlers, and their families through Early Head Start-Child Care (EHS-CC) Partnerships, and/or through the expansion of Migrant and Seasonal Head Start services. ACF solicits applications from public entities, including states, or private non-profit organizations, including community-based or faith-based organizations, or for-profit agencies that meet eligibility for applying as stated in section 42 U.S.C. 9840A of the Head Start Act. Interested applicants may email OHSgrants@koniag-gs.com for additional information.OHS encourages interested applicants to visit https://www.acf.hhs.gov/grants/how-apply-grant. This webpage provides information on applying for grants, registering and applying through Grants.gov, submitting an application, and understanding the grant review process.

The Bureau of Counterterrorism (CT) of the U.S. Department of State announces a Request for Statements of Interest and Capacity (RSOIC) from organizations interested in implementing a project to facilitate a joint exercise with West African civilian security agencies to promote cross-border coordination, information sharing, and collaboration on counterterrorism threats.

This program provides funding to non-profit organizations in Pennsylvania to develop and promote tourism initiatives that encourage overnight stays through events, facility improvements, and marketing efforts.

This program provides funding to certified community development financial institutions to strengthen their operations and expand services for small businesses and underserved communities in Pennsylvania.

The Seminole County is currently accepting grant applications for the Home-ARP Program, a critical initiative designed to mitigate homelessness and enhance housing stability for qualifying populations within the county. This program is a direct outgrowth of the HOME-American Rescue Plan (HOME-ARP), which saw Congress allocate $5 billion as part of the broader $1.9 trillion COVID-19 pandemic relief efforts on March 11, 2021. The Department of Housing and Urban Development (HUD) administers these funds, with Seminole County having received $3,046,438. This funding was officially approved by the Board of County Commissioners on March 14, 2023, and subsequently by HUD, underscoring its alignment with federal strategies to address housing insecurity exacerbated by the pandemic. The primary target beneficiaries of the Home-ARP Program are individuals and families experiencing or at risk of homelessness, as well as other qualifying populations as defined by HUD. The program's overarching impact goal is to significantly reduce homelessness and increase housing stability across Seminole County. This will be achieved through a multi-faceted approach, including the development of affordable rental housing, provision of supportive services, and capacity building for non-profit organizations. By focusing on these areas, the program aims to create a more resilient and equitable housing landscape for vulnerable residents. The program's priorities and focuses are clearly outlined through its funding allocation. A substantial portion, $2,137,151, is dedicated to the development of affordable rental housing, highlighting a strategic emphasis on increasing the supply of safe and accessible housing units. Additionally, $300,000 is allocated for supportive services, recognizing that stable housing often requires concurrent support for health, employment, and other social needs. Furthermore, $152,321 is earmarked for Non-Profit Capacity Building/Operating Costs, demonstrating an understanding that strong, well-resourced community partners are essential for effective program implementation. Finally, $456,966 is allocated for administration and planning, ensuring efficient oversight and strategic deployment of resources. Expected outcomes include a measurable reduction in the number of individuals experiencing homelessness in Seminole County, an increase in the availability of affordable rental housing units, and improved access to essential supportive services for at-risk populations. The program anticipates strengthening the capacity of local non-profit and for-profit organizations to address community development and housing needs. These outcomes will be achieved through projects implemented either directly by the County or in partnership with qualified non-profit agencies or for-profit organizations, aligning with a theory of change that posits collaborative efforts and strategic investment in housing and support services will lead to enhanced housing stability and a decrease in homelessness.

This grant provides financial support to community-based news organizations in western Iowa to enhance local journalism and ensure residents have access to accurate and engaging news coverage.

This program provides financial assistance and support to new small businesses in Santa Ana, helping them thrive during their first three years of operation.

This program provides funding for community organizations and local governments to acquire technology devices to help bridge the digital divide for those facing affordability challenges.

The Administration for Children and Families (ACF), Office of Head Start (OHS) announces the availability of approximately $102 million to be competitively awarded for the purpose of expanding access to high-quality, comprehensive services to low-income infants, toddlers, and their families through Early Head Start-Child Care (EHS-CC) Partnerships, or through the expansion of Head Start services and/or Early Head Start services. ACF solicits applications from public entities, including states, or private non-profit organizations, including community-based or faith-based organizations, or for-profit agencies that meet eligibility for applying as stated in section 42 U.S.C. 9840A of the Head Start Act. Interested applicants may email OHSgrants@koniag-gs.com for additional information.OHS encourages interested applicants to visit https://www.acf.hhs.gov/grants/how-apply-grant. This webpage provides information on applying for grants, registering and applying through Grants.gov, submitting an application, and understanding the grant review process.

The Effectiveness Monitoring Committee (EMC) is seeking project proposals that: (1)   Address one or more of the EMC’s Research Themes and Critical Monitoring Questions and; (2)   Address natural resource protection issues that are important for California forestlands. The critical monitoring questions are organized under 12 Research Themes. Four prioritized critical questions were determined by vote amongst the current EMC members at the beginning of each calendar year:  Are the FPRs and associated regulations effective in...  Question 1h: managing WLPZs to reduce or minimize potential fire behavior and rate of spread? Question 6c:  managing fuel loads, vegetation patterns and fuel breaks for fire hazard reduction? Question 6d: managing forest structure and stocking standards to promote wildfire resilience? Question 12a: improving overall forest wildfire resilience and the ability of forests to respond to climate change (e.g., in response to drought or bark beetle; reducing plant water stress) and variability, and extreme weather events (evaluate ecosystem functional response to fuel reduction and forest health treatments)? I.       FUNDING AVAILABILITY. Funding available for newly proposed projects is anticipated as follows: $973,392 over three FYs beginning in 2024/25, comprising: $173,232 in FY 2024/25; $375,160 in FY 2025/26; and $425,000 in FY 2025/26. II.     AWARD LIMITATIONS. Applicants requesting more than the stated annual amount available for funding will not be considered. In the case that EMC funding for the full three years is awarded to one new project, project solicitation may not occur in the subsequent two FYs. While the EMC may choose to fund projects that span multiple FYs up to the annual funding cap, the EMC generally prefers to fund multiple research projects annually. Proposers should keep this in mind when developing their project and annual budget requests. Longer-term projects (greater than three years) may re-apply for funding for additional years through the competitive grants process advertised in the EMC’s Request for Proposals. Annual allocations are dependent upon demonstrated progress towards project completion pursuant to the project schedule and workplan.  a.      ELIGIBLE ACTIVITIES. Eligible projects will test one or more specific FPRs or other rule or regulation under the Board’s jurisdiction and which addresses one or more of the EMC’s Research Themes and Critical Monitoring Questions. Proposed projects must clearly apply to management activities on private timberlands in California. Projects on public land may be eligible for EMC funding provided they clearly apply to the activities and systems that also exist on non-federal timberland. b.      ELIGIBLE ORGANIZATIONS. Eligible applicants are local, state, and federal agencies including federal land management agencies; institutions of higher education; special purpose districts (e.g., public utilities districts, fire districts, conservation districts, and ports); Native American tribes; private landowners; for-profit entities; and non-profit 501(c)(3) organizations.

This grant supports the purchase of new, more efficient equipment to enhance business operations in Goshen County. It focuses on helping businesses become more productive and competitive by upgrading their operational tools. Technology upgrades and deferred maintenance are not eligible. Applicants must seek multiple bids, preferably from local contractors. Deadlines: Applications due first Friday of November, February, May, August

This solicitation aims to reduce building dependency on grid electricity, increase energy efficiency of HVAC equipment operating on DC power, decrease burdens – and enhance access – to solar and heat pump adoption, and create business and manufacturing opportunities for those who develop DC HVAC nanogrid modules. The potential technology solution could be a modular system that includes an appropriately-sized PV array and energy storage integrated with a DC HVAC system. Such systems could support cost-effective decarbonization, summer electric demand management, and increased market adoption of clean HVAC electrification while avoiding the complexities of interconnection and stand-alone PV and storage installation, particularly for those in under-resourced communities. These systems could provide the benefits of solar and storage to ratepayers who have limited roof space or cannot afford a larger building-level PV/storage system. The installation would ideally be similar to an HVAC replacement, in that it would not require an inverter, onsite electrician, interconnection agreement, conduits, wiring, electric panel upgrades, or other utility-side requirements. Power from the solar PV and energy storage would be used entirely onsite and would not be exported to the grid. Rather, these systems would gain efficiency benefits from direct DC connections among the solar PV, storage, and HVAC equipment. Projects under this initiative could also eliminate or reduce building HVAC load during peak hours in summer months, improving reliability on the grid. The unit would typically be powered by solar PV and energy storage, except when either solar or stored energy is unavailable; at those times, the HVAC would use an AC/DC converter to be powered by the grid. The HVAC could continue operation uninterrupted during a grid outage when there is adequate solar and storage power available to meet the HVAC system’s load. Funded projects must develop and demonstrate the following technologies in existing buildings: ·       DC-powered HVAC equipment that directly uses onsite solar generated electricity; ·       Energy and/or thermal storage integrated into the system to improve cost effectiveness; and ·                A transfer switch incorporated into the module to isolate generation equipment from the grid and simplify installation. Projects must fall within one of the following project groups: ·       Group 1: Residential DC HVAC Nanogrid; and ·       Group 2: Commercial DC HVAC Nanogrid.

This funding opportunity supports national neuroscience education programs that provide hands-on research experiences and training for graduate students, postdoctoral researchers, and junior faculty to enhance the biomedical research workforce.

This grant provides funding to Goshen County businesses to enhance their workforce training initiatives. It aims to complement potential funding from Wyoming Workforce Development, addressing the increasingly competitive nature of workforce development funds. The grant supports the creation of training programs that improve skills and capabilities, thereby boosting job creation and economic prosperity within the county. Deadlines: Applications due first Friday of November, February, May, August

This grant caters to unique and innovative projects that do not fit the conventional frameworks of the other sub-grants but still demonstrate significant economic development merit. Eligible projects may include feasibility studies, engineered drawings, architecture plans, and planning studies. These projects should aim to significantly impact the economic landscape of Goshen County. Deadlines: Applications due first Friday of November, February, May, August