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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

F26AS00084 Aquatic Invasive Species Grants to Great Lakes Tribes - Fiscal Year 2026 Great Lakes Restoration Initiative
$100,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Dec 31, 2026

Date Added

May 8, 2026

This funding opportunity provides financial support to Great Lakes Tribes for developing and implementing plans to manage and control aquatic invasive species that threaten the region's ecosystems and waterways.

Environment
Native American tribal organizations
Butte Creek/Sutter Bypass Weir 1 Improvement Design and Permitting Project
$850,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Jul 19, 2026

Date Added

May 21, 2026

This funding opportunity provides financial support for organizations to design and permit improvements to a weir structure in California, enhancing fish passage and aquatic ecosystems in the Central Valley.

Natural Resources
Nonprofits
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Sep 6, 2024

This funding opportunity supports researchers investigating how bariatric surgery influences cancer risk through biological mechanisms, encouraging studies that go beyond weight loss to explore long-term health effects.

Education
State governments
DoW Hearing Restoration Focused Research Award
$1,200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 10, 2026

Date Added

May 5, 2026

This funding opportunity supports research projects aimed at developing therapies and diagnostic tools to address hearing loss and auditory system injuries relevant to military personnel and veterans.

Health
Nonprofits
Centers of Excellence in Genomic Science (CEGS)
$5,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 24, 2026

Date Added

Sep 24, 2025

This funding opportunity supports interdisciplinary teams in advancing innovative genomic research and technologies to tackle significant biomedical challenges, welcoming a diverse range of eligible organizations and institutions.

Health
State governments
FY25 ONR Office Of Naval Research (ONR) Science, Technology, Engineering, and Mathematics(STEM) Education and Workforce Program
Contact for amount
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Jun 30, 2026

Date Added

Jul 8, 2025

This grant provides funding to a variety of organizations to enhance STEM education and workforce development initiatives, aiming to increase student engagement and proficiency in science, technology, engineering, and mathematics.

Education
For profit organizations other than small businesses
INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
$3,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2028

Date Added

Sep 26, 2025

This funding opportunity supports innovative clinical trials aimed at improving health and quality of life for individuals with Down syndrome, inviting a wide range of organizations to apply for financial assistance in addressing critical health issues associated with the condition.

Health
Nonprofits
Toolkits for Dissemination of Genomic Technologies
$50,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 24, 2026

Date Added

Sep 24, 2025

This funding opportunity provides resources to a wide range of organizations to create and share comprehensive toolkits that facilitate the adoption and implementation of genomic technologies in health-related research.

Health
City or township governments
Clinical and Translational Science Award (UM1 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 28, 2027

Date Added

Sep 5, 2024

This funding opportunity supports medical research institutions in developing collaborative hubs to accelerate the translation of scientific discoveries into effective treatments and address health disparities through innovative research and training programs.

Health
State governments
DoW Spinal Cord Injury, Clinical Trial Award
$4,960,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This grant provides funding for clinical trials aimed at improving treatment and management strategies for spinal cord injury, benefiting military Service Members, Veterans, and civilians.

Health
Nonprofits
DoW Prostate Cancer, Early Investigator Research Award
$630,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This grant provides funding and mentorship to early-career researchers focused on innovative prostate cancer studies, aiming to improve patient outcomes and advance their professional development.

Health
Nonprofits
Battery Network Broad Agency Announcement
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Sep 1, 2026

Date Added

Mar 20, 2025

This funding opportunity supports innovative research and development projects that improve defense logistics, supply chain resilience, and operational readiness for organizations aligned with national security objectives.

Science and Technology
For profit organizations other than small businesses
DoW Ovarian Cancer, Clinical Trial Award
$2,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 1, 2026

Date Added

May 5, 2026

This funding opportunity supports clinical trials aimed at improving the treatment and management of ovarian cancer, benefiting patients including Service Members, Veterans, and their families.

Health
Nonprofits
Cellular and Biochemical Engineering
$3,350,043
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for researchers to develop innovative engineering solutions that improve the production of therapeutic cells and biochemicals, focusing on fundamental cellular and biomolecular processes.

Science and Technology
For profit organizations other than small businesses
Local Food Promotion Program Fiscal Year 2026
$500,000
U.S. Department of Agriculture (Agricultural Marketing Service)
Federal

Application Deadline

Jun 5, 2026

Date Added

Apr 22, 2026

This funding opportunity supports a variety of organizations in developing and expanding local food systems that connect producers to consumers, enhancing access to local foods and improving economic opportunities for multiple stakeholders.

Agriculture
Nonprofits
DoW Vision, Translational Research Award
$1,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research aimed at developing new treatments and technologies for vision-related injuries and dysfunctions resulting from military service.

Health
Nonprofits
Pathways to Enable Open-Source Ecosystems
$1,500,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jun 2, 2025

This program provides funding to U.S.-based organizations to develop and sustain open-source ecosystems that support community-driven innovations in science and technology.

Science and Technology
Public and State controlled institutions of higher education
Chemical Oceanography
$2,000,000
National Science Foundation
Federal

Application Deadline

Aug 17, 2026

Date Added

Mar 6, 2025

This grant provides funding for researchers at U.S. colleges, universities, and nonprofit organizations to study marine chemistry and its impact on global environmental processes.

Science and Technology
State governments
Pioneering Aerospace Capabilities, Engineering and Research (PACER)
$50,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal
Rolling

Application Deadline

May 10, 2043

Date Added

Jul 26, 2023

This grant provides funding for research and development of innovative aerospace technologies to improve military air vehicle performance and capabilities.

Science and Technology
Small businesses
NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 9, 2026

Date Added

Nov 8, 2024

This funding opportunity supports early-career scientists in neuroscience by providing training and resources to help them become independent researchers through innovative projects and mentorship.

Health
State governments