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Grants for Small businesses - Federal

Explore 1,755 grant opportunities

EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 17, 2026

Date Added

Nov 25, 2024

This funding opportunity supports research partnerships between resource-limited institutions and experienced technology developers to enhance the use of innovative neurotechnologies for better understanding and treating brain-related conditions.

Health
Public and State controlled institutions of higher education
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
DoW Breast Cancer, Breakthrough Award Level 3
$7,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports advanced breast cancer research projects that aim to make significant breakthroughs in prevention, treatment, and understanding of the disease, particularly for Service Members, Veterans, and their families.

Health
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This funding opportunity supports researchers and organizations developing biologics-based therapies for nervous and neuromuscular disorders, facilitating their progression from early discovery to clinical trials.

Education
State governments
NSF Research: National Facilities
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 21, 2024

This grant provides funding to research organizations for the operation of specialized national facilities that offer advanced scientific instruments and resources to support diverse research communities and educational outreach.

Science and Technology
Public and State controlled institutions of higher education
Community Connect Grant Program
$3,000,000
U.S. Department of Agriculture (Rural Utilities Service)
Federal

Application Deadline

Jun 29, 2026

Date Added

May 14, 2026

This program provides financial assistance to various organizations and governments to build high-speed internet infrastructure in underserved rural communities, enhancing access to essential services and economic opportunities.

Infrastructure
State governments
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity supports researchers in developing assays and identifying potential neurotherapeutic agents for neurological and neuromuscular disorders, facilitating early-stage drug discovery efforts.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-25-168
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2027

Date Added

May 14, 2025

This grant provides funding to U.S. institutions to develop research training programs for predoctoral and postdoctoral students in biomedical and related fields, ensuring a skilled workforce to tackle health research challenges.

Education
State governments
Beginning Farmer and Rancher Development Program
$750,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Jun 16, 2026

Date Added

May 14, 2026

This program provides funding to collaborative partnerships that offer education and support to individuals with ten or fewer years of farming or ranching experience, helping them establish and sustain successful agricultural operations.

Agriculture
Nonprofits
DoW Alzheimers Transforming Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 24, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research aimed at reducing the risk and preventing Alzheimer’s disease and related dementias, particularly focusing on military health exposures and diverse risk factors, with an emphasis on community collaboration and health disparities.

Health
Nonprofits
DoD Breast Cancer, Transformative Breast Cancer Consortium Development Award
$140,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Jul 8, 2026

Date Added

May 5, 2026

This grant provides funding to researchers and institutions to form collaborative teams focused on innovative breast cancer research, ultimately aiming to improve prevention, diagnosis, and treatment of the disease.

Health
Nonprofits
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
$5,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 1, 2025

This funding opportunity supports a wide range of fundamental scientific research projects across various disciplines, including energy, environment, and national security, aimed at advancing knowledge and innovation in the United States.

Science and Technology
Individuals
Research and Development of Naval Power and Energy Systems (N00024-19-R-4145 Broad Agency Announcement (BAA))
Contact for amount
U.S. Department of Defense (Department of the Navy)
Federal

Application Deadline

Feb 6, 2028

Date Added

Aug 25, 2025

This grant provides funding for innovative research projects from industry and academia to improve naval shipboard power and energy systems, focusing on efficiency, resilience, and advanced technologies.

Science and Technology
For profit organizations other than small businesses
Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 5, 2026

Date Added

Sep 27, 2025

This funding opportunity supports collaborative pilot studies using advanced microphysiological systems to explore new approaches in understanding and treating type 2 diabetes, inviting a diverse range of applicants from various sectors.

Health
City or township governments
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 24, 2024

This funding opportunity supports a wide range of organizations in planning and conducting clinical trials focused on improving dental, oral, and craniofacial health interventions.

Health
State governments
Collaborative Program Grant for Multidisciplinary Teams (RM1 - Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Feb 3, 2023

This funding opportunity supports multidisciplinary research teams in the U.S. working on complex biomedical questions, with a focus on advancing foundational biological processes and addressing critical health issues.

Health
State governments