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Grants for Small businesses - Federal

Explore 1,841 grant opportunities

NIH Directors Pioneer Award (DP1 Clinical Trial Optional)
$700,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 9, 2026

Date Added

Dec 12, 2025

This funding opportunity supports innovative researchers in the biomedical and health fields who propose groundbreaking ideas that could significantly advance scientific knowledge and improve human health.

Health
Public and State controlled institutions of higher education
DoW Vision, Translational Research Award
$1,600,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research aimed at developing new treatments and technologies for vision-related injuries and dysfunctions resulting from military service.

Health
Nonprofits
Pathways to Enable Open-Source Ecosystems
$1,500,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jun 2, 2025

This program provides funding to U.S.-based organizations to develop and sustain open-source ecosystems that support community-driven innovations in science and technology.

Science and Technology
Public and State controlled institutions of higher education
Great Health for America
$8,000,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCCDPHP)
Federal

Application Deadline

Aug 3, 2026

Date Added

Jul 3, 2026

This funding opportunity provides substantial financial support for community-driven projects aimed at reducing childhood chronic diseases in specific U.S. communities by addressing key health determinants like nutrition and access to care.

Health
State governments
Chemical Oceanography
$2,000,000
National Science Foundation
Federal

Application Deadline

Aug 17, 2026

Date Added

Mar 6, 2025

This grant provides funding for researchers at U.S. colleges, universities, and nonprofit organizations to study marine chemistry and its impact on global environmental processes.

Science and Technology
State governments
Pioneering Aerospace Capabilities, Engineering and Research (PACER)
$50,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal
Rolling

Application Deadline

May 10, 2043

Date Added

Jul 26, 2023

This grant provides funding for research and development of innovative aerospace technologies to improve military air vehicle performance and capabilities.

Science and Technology
Small businesses
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 23, 2025

This funding opportunity supports research projects that develop and test culturally relevant health interventions to improve health outcomes in Native American, Alaska Native, and Native Hawaiian communities, emphasizing community engagement and sustainability.

Health
State governments
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 16, 2027

Date Added

Oct 29, 2024

This funding opportunity provides financial support for researchers to explore and generate preliminary data on understudied proteins linked to rare diseases, with a focus on enhancing knowledge and tools for future studies.

Health
State governments
DoWs Energy, Installations, and Environment Innovation Partners Programs
Contact for amount
U.S. Department of Defense (Washington Headquarters Services)
Federal

Application Deadline

Jan 8, 2028

Date Added

Feb 28, 2025

This funding opportunity supports a variety of organizations and individuals in developing innovative projects that promote environmental stewardship and energy resilience on military installations, enhancing their operational effectiveness and sustainability.

Environment
Nonprofits
DoW Duchenne Muscular Dystrophy, Idea Development Award
$500,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 18, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at developing effective treatments for Duchenne muscular dystrophy, targeting both pediatric and nonambulatory populations, and is open to independent researchers from various sectors worldwide.

Science and Technology
Nonprofits
Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2027

Date Added

Nov 19, 2024

This grant provides funding for researchers to develop innovative computational tools and methods that enhance genomic research and data science, with a focus on broad applications to improve human health.

Education
State governments
Decision, Risk and Management Sciences
Contact for amount
National Science Foundation
Federal

Application Deadline

Aug 18, 2026

Date Added

Feb 3, 2024

This program provides funding for researchers at U.S. institutions to conduct studies that improve decision-making processes across various fields, addressing important societal issues through theoretical and practical insights.

Science and Technology
Nonprofits
Fluid Dynamics
$9,175,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for researchers to explore and advance the science of fluid dynamics, focusing on innovative methods and applications that can benefit society and industry.

Science and Technology
For profit organizations other than small businesses
DoW, Peer Reviewed Cancer, Impact Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 5, 2026

Date Added

May 7, 2026

This funding opportunity supports advanced cancer research projects that aim to improve patient care and treatment outcomes for military personnel, veterans, and their families.

Health
Nonprofits
DoW Peer Reviewed Medical, Lifestyle and Applied Health Research Award
$4,200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 11, 2026

This funding opportunity provides substantial financial support for clinical research and trials focused on nonpharmacological health interventions that improve the well-being of military personnel, veterans, and their families.

Health
Nonprofits
Special Program Announcement for Office of Naval Research Research Opportunity: FY27 Communications and Networking Applied Research
$500,000
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Nov 16, 2026

Date Added

Jun 17, 2026

This funding opportunity supports applied research in communications and networking technologies to enhance the operational effectiveness of the Navy and Marine Corps, targeting a wide range of eligible entities including academic institutions, private industry, and nonprofit organizations.

Science and Technology
Nonprofits
Air Dominance Broad Agency Announcement (BAA)
$750,000,000
U.S. Department of Defense (Munitions Directorate)
Federal

Application Deadline

Oct 31, 2029

Date Added

Apr 15, 2025

This funding opportunity supports a wide range of research and technology development aimed at enhancing the U.S. Air Force's capabilities in air dominance and national defense, inviting participation from educational institutions, nonprofits, private industry, and small businesses.

Science and Technology
Small businesses
DoW Alzheimers Transforming Care Award
$1,900,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 24, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research and clinical trials aimed at improving dementia care for Service Members, Veterans, their families, and caregivers, with a focus on practical solutions that enhance quality of life and reduce caregiver burden.

Health
Nonprofits
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 26, 2027

Date Added

Dec 17, 2024

This funding opportunity supports early career researchers in genomics, particularly those from underrepresented backgrounds, to establish independent research careers through innovative projects that advance the field of genomic sciences.

Science and Technology
Public and State controlled institutions of higher education
DoW Prostate Cancer, Physician Research Award
$1,100,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports early-career physician researchers dedicated to advancing prostate cancer studies that improve patient outcomes and enhance clinical care through mentored research experiences.

Health
Nonprofits