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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 26, 2027

Date Added

Dec 17, 2024

This funding opportunity supports early career researchers in genomics, particularly those from underrepresented backgrounds, to establish independent research careers through innovative projects that advance the field of genomic sciences.

Science and Technology
Public and State controlled institutions of higher education
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 2, 2027

Date Added

Nov 1, 2024

This funding opportunity supports research that investigates how individual biological factors, such as genetics and diet, affect people's responses to probiotic therapies, aiming to develop more effective and personalized treatments.

Education
State governments
DoW Breast Cancer, Clinical Research Extension Award
$8,400,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Nov 18, 2026

Date Added

Aug 21, 2026

This grant provides funding for innovative research projects that extend the data collection and analysis of existing breast cancer clinical studies, aiming to improve patient outcomes and advance the understanding of breast cancer.

Science and Technology
Nonprofits
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Oct 24, 2024

This funding opportunity supports the development of advanced sensor technologies that measure behavior and synchronize it with neural activity, encouraging collaboration among researchers, engineers, and data scientists to enhance our understanding of brain function in real-world settings.

Health
State governments
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 19, 2026

Date Added

Jul 3, 2025

This funding opportunity provides financial support to organizations maintaining and improving established informatics tools that enhance cancer research and management, ensuring they remain effective and relevant for the research community.

Science and Technology
Public and State controlled institutions of higher education
DoW Military Burn, Technology/Therapeutic Development Award
$1,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers and organizations developing innovative technologies and treatments to improve burn care for military personnel in combat and training environments.

Science and Technology
Nonprofits
EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iTeamBCP (RM1 Clinical Trial Optional)
$8,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 7, 2026

Date Added

Aug 29, 2025

This grant provides funding for interdisciplinary research teams to explore how neural circuits function in the brain, focusing on mechanistic insights and integrating experimental and computational approaches.

Science and Technology
Public and State controlled institutions of higher education
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
DoW Breast Cancer, Breakthrough Award Level 3
$7,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports advanced breast cancer research projects that aim to make significant breakthroughs in prevention, treatment, and understanding of the disease, particularly for Service Members, Veterans, and their families.

Health
Nonprofits
DoW Bone Marrow Failure, Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at understanding and curing bone marrow failure diseases, targeting both inherited and acquired conditions, and is open to a wide range of researchers and organizations.

Science and Technology
Nonprofits
BJS FY 2026 Criminal History Record Assessment and Research Program (CHRARP)
$1,750,000
U.S. Department of Justice (Bureau of Justice Statistics)
Federal

Application Deadline

Sep 21, 2026

Date Added

Aug 14, 2026

This funding opportunity provides financial support for organizations to improve the processing and analysis of criminal history records, enabling research on crime and recidivism while enhancing data quality and standardization across jurisdictions.

Information and Statistics
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This funding opportunity supports researchers and organizations developing biologics-based therapies for nervous and neuromuscular disorders, facilitating their progression from early discovery to clinical trials.

Education
State governments
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
$1,750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 6, 2026

Date Added

Nov 19, 2024

This funding opportunity supports researchers in analyzing existing data to improve understanding of cancer risk, prevention, and outcomes, encouraging innovative approaches without the need for extensive new data collection.

Education
Public and State controlled institutions of higher education
Middle East Regional Cooperation (MERC)
$2,000,000
U.S. Department of State (Assistance Coordination)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 7, 2026

This grant provides funding for collaborative scientific research and technology development projects between Israel and eligible countries in the Middle East and North Africa, focusing on practical applications in critical areas like energy, water, agriculture, and health.

Science and Technology
Public and State controlled institutions of higher education
Fostering the Future Together: Empowering Youth for a Safe Digital World
$3,000,000
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Sep 10, 2026

Date Added

Aug 3, 2026

This funding opportunity provides financial support to organizations working in eligible countries to empower youth at risk of child labor through education, digital skills training, and online safety initiatives.

Youth
Nonprofits
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity supports researchers in developing assays and identifying potential neurotherapeutic agents for neurological and neuromuscular disorders, facilitating early-stage drug discovery efforts.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-25-168
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2027

Date Added

May 14, 2025

This grant provides funding to U.S. institutions to develop research training programs for predoctoral and postdoctoral students in biomedical and related fields, ensuring a skilled workforce to tackle health research challenges.

Education
State governments