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Grants for Small businesses - Federal

Explore 1,962 grant opportunities

DoW Alzheimers Transforming Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 24, 2026

Date Added

May 4, 2026

This funding opportunity supports innovative research aimed at reducing the risk and preventing Alzheimer’s disease and related dementias, particularly focusing on military health, traumatic brain injury, and health disparities.

Health
Nonprofits
DoW Parkinsons, Early Investigator Research Award
$1,000,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Nov 6, 2026

Date Added

Jun 19, 2026

This funding opportunity supports early-career researchers in pursuing innovative studies related to Parkinson's disease, with a focus on improving outcomes for military populations and the general public.

Science and Technology
Nonprofits
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
$5,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 1, 2025

This funding opportunity supports a wide range of fundamental scientific research projects across various disciplines, including energy, environment, and national security, aimed at advancing knowledge and innovation in the United States.

Science and Technology
Individuals
Research and Development of Naval Power and Energy Systems (N00024-19-R-4145 Broad Agency Announcement (BAA))
Contact for amount
U.S. Department of Defense (Department of the Navy)
Federal

Application Deadline

Feb 6, 2028

Date Added

Aug 25, 2025

This grant provides funding for innovative research projects from industry and academia to improve naval shipboard power and energy systems, focusing on efficiency, resilience, and advanced technologies.

Science and Technology
For profit organizations other than small businesses
DOW Combat Readiness Medical Research Program Translational Research Award
$2,450,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Nov 18, 2026

Date Added

Jun 25, 2026

This funding opportunity supports innovative medical research projects aimed at improving trauma care for military personnel in combat and austere environments, with potential applications for civilian emergency medicine.

Science and Technology
Nonprofits
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 24, 2024

This funding opportunity supports a wide range of organizations in planning and conducting clinical trials focused on improving dental, oral, and craniofacial health interventions.

Health
State governments
Engineering (ENG): Chemical, Bioengineering, Energy, and Transport Systems (CBET)
$100,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 18, 2026

This funding opportunity supports innovative engineering research in chemical, bioengineering, energy, and transport systems, aimed at advancing foundational knowledge and technology across various disciplines.

Science and Technology
City or township governments
DoW Reconstructive Transplant, Investigator-Initiated Research Award
$1,000,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Aug 5, 2026

This grant provides funding for innovative research projects aimed at improving reconstructive transplantation techniques and patient care for military Service Members, Veterans, and their families.

Science and Technology
Nonprofits
F26AS00083 Aquatic Invasive Species Grants to Great Lakes States - Fiscal Year 2026 Great Lakes Restoration Initiative
$600,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Dec 31, 2026

Date Added

Jun 11, 2026

This funding opportunity provides financial support to Great Lakes state agencies for implementing strategies to combat aquatic invasive species and protect the region's ecosystems and economy.

Natural Resources
State governments
DoW Spinal Cord Injury, Clinical Translation Research Award
$2,160,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 12, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative clinical research projects aimed at improving treatments and outcomes for individuals with spinal cord injuries, particularly those involving military Service Members, Veterans, and civilians.

Health
Nonprofits
Advanced Manufacturing (AM)
Contact for amount
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Jul 6, 2018

This grant provides funding for researchers and innovators to develop advanced manufacturing technologies that enhance American manufacturing capabilities and support national prosperity and security.

Science and Technology
City or township governments
SEFSC Bluefin Tuna Research Program
$300,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Dec 31, 2026

Date Added

Aug 28, 2026

This funding opportunity provides financial support for research projects aimed at improving the management and understanding of Atlantic bluefin tuna fisheries, targeting institutions, nonprofits, and individuals involved in marine science and conservation.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Sep 26, 2024

This funding opportunity provides financial support to U.S. institutions, particularly those historically underfunded, to produce and distribute specialized tools for neuroscience research focused on specific brain cell types.

Education
State governments
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 7, 2027

Date Added

Apr 25, 2024

This grant provides funding and support for early-career researchers in the biomedical, behavioral, or clinical sciences to gain the skills and experience needed to become independent investigators, without leading their own clinical trials.

Health
State governments
ROSES 2025: D.4 Theoretical and Computational Astrophysics Networks
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Dec 3, 2026

Date Added

Sep 1, 2026

This funding opportunity provides financial support for U.S. institutions engaged in theoretical and computational astrophysics research, encouraging collaboration and innovation in the field.

Science and Technology
Nonprofits
Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed
$50,000
U.S. Department of the Interior (National Park Service)
Federal

Application Deadline

Nov 4, 2026

Date Added

Aug 28, 2026

This grant provides funding to various organizations, including local governments and nonprofits, to promote outdoor recreation and heritage tourism in the Chesapeake Bay watershed, fostering community economic development and enhancing visitor experiences.

Community Development
State governments
DoW Duchenne Muscular Dystrophy, Clinical/Translational Research Award
$1,900,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 18, 2026

Date Added

Jun 18, 2026

This funding opportunity supports advanced research projects aimed at developing effective therapies for Duchenne muscular dystrophy, benefiting individuals across all ages and improving their quality of life.

Science and Technology
Nonprofits
Information Processing Techniques Office Office-Wide
Contact for amount
U.S. Department of Defense (DARPA - Information Processing Technologies Office)
Federal

Application Deadline

Jun 22, 2027

Date Added

Jun 23, 2026

This grant provides funding for innovative research and development in advanced information technologies aimed at enhancing national security, particularly in areas like artificial intelligence, security, and resilient computing systems, and is open to a wide range of organizations, including universities and small businesses.

Science and Technology
For profit organizations other than small businesses
Biological Technologies
$2,000,000
U.S. Department of Defense (DARPA - Biological Technologies Office)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 2, 2025

This grant provides funding for innovative research projects that utilize biological technologies to enhance U.S. national security, targeting a wide range of applicants including nonprofits, educational institutions, and businesses.

Science and Technology
Nonprofits
Applied Mathematics
Contact for amount
National Science Foundation
Federal

Application Deadline

Nov 16, 2026

Date Added

Mar 17, 2025

This funding opportunity supports researchers in mathematics who are working on innovative solutions to scientific and engineering challenges, while also promoting the training of emerging applied mathematicians.

Science and Technology
Public and State controlled institutions of higher education