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Grants for Small businesses - Federal

Explore 1,841 grant opportunities

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 2, 2027

Date Added

Nov 1, 2024

This funding opportunity supports research that investigates how individual biological factors, such as genetics and diet, affect people's responses to probiotic therapies, aiming to develop more effective and personalized treatments.

Education
State governments
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Oct 24, 2024

This funding opportunity supports the development of advanced sensor technologies that measure behavior and synchronize it with neural activity, encouraging collaboration among researchers, engineers, and data scientists to enhance our understanding of brain function in real-world settings.

Health
State governments
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 19, 2026

Date Added

Jul 3, 2025

This funding opportunity provides financial support to organizations maintaining and improving established informatics tools that enhance cancer research and management, ensuring they remain effective and relevant for the research community.

Science and Technology
Public and State controlled institutions of higher education
GlobalX Challenge 26.1: AI-Native Air Interface for Tactical Communication Networks
$500,000
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Aug 31, 2026

Date Added

Jun 10, 2026

This funding opportunity provides financial support for international research organizations to develop innovative AI-driven communication technologies that enhance tactical networks in challenging environments, with a focus on collaboration and measurable improvements in performance.

Science and Technology
Nonprofits
Rehabilitation Research and Training Center (RRTC) on Interventions to Promote Community Living Among People with Disabilities
$925,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Jul 29, 2026

Date Added

Sep 8, 2025

This funding opportunity supports research and training initiatives to improve community living for individuals with disabilities by addressing barriers to independence and inclusion.

Science and Technology
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2026

Date Added

Sep 26, 2024

This grant provides funding for researchers to develop small molecule drugs targeting nervous system disorders, with support from NIH resources for drug discovery and clinical testing.

Education
State governments
Maternal Produce Prescription Program (MP3)
$500,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Jul 17, 2026

Date Added

Mar 12, 2026

This funding opportunity provides financial support to organizations that create programs helping low-income pregnant and postpartum women access fresh fruits and vegetables, along with nutrition education, to improve their health and that of their families.

Health
State governments
DoD Multiple Sclerosis Investigator-Initiated Research Award
$1,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 13, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, treatment, and quality of life for individuals affected by multiple sclerosis, particularly benefiting Service Members, Veterans, and their families.

Health
Nonprofits
DoW Military Burn, Technology/Therapeutic Development Award
$1,800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers and organizations developing innovative technologies and treatments to improve burn care for military personnel in combat and training environments.

Science and Technology
Nonprofits
EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
DoW Kidney Cancer, Concept Award
$120,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 11, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at advancing the understanding and treatment of kidney cancer, targeting researchers and organizations dedicated to groundbreaking medical discoveries.

Science and Technology
Nonprofits
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
DoW Breast Cancer, Breakthrough Award Level 3
$7,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports advanced breast cancer research projects that aim to make significant breakthroughs in prevention, treatment, and understanding of the disease, particularly for Service Members, Veterans, and their families.

Health
Nonprofits
DoW Bone Marrow Failure, Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 18, 2026

This funding opportunity supports innovative research projects aimed at understanding and curing bone marrow failure diseases, targeting both inherited and acquired conditions, and is open to a wide range of researchers and organizations.

Science and Technology
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This funding opportunity supports researchers and organizations developing biologics-based therapies for nervous and neuromuscular disorders, facilitating their progression from early discovery to clinical trials.

Education
State governments
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
$1,750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 6, 2026

Date Added

Nov 19, 2024

This funding opportunity supports researchers in analyzing existing data to improve understanding of cancer risk, prevention, and outcomes, encouraging innovative approaches without the need for extensive new data collection.

Education
Public and State controlled institutions of higher education
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity supports researchers in developing assays and identifying potential neurotherapeutic agents for neurological and neuromuscular disorders, facilitating early-stage drug discovery efforts.

Health
State governments