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Grants for Small businesses - Federal

Explore 1,853 grant opportunities

DoW Duchenne Muscular Dystrophy, Clinical/Translational Research Award
$1,900,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 18, 2026

Date Added

Jun 18, 2026

This funding opportunity supports advanced research projects aimed at developing effective therapies for Duchenne muscular dystrophy, benefiting individuals across all ages and improving their quality of life.

Science and Technology
Nonprofits
Information Processing Techniques Office Office-Wide
Contact for amount
U.S. Department of Defense (DARPA - Information Processing Technologies Office)
Federal

Application Deadline

Jun 22, 2027

Date Added

Jun 23, 2026

This funding opportunity supports innovative research in artificial intelligence, security, and complex systems, inviting a wide range of organizations, including academic institutions and private companies, to propose groundbreaking projects that enhance national security.

Science and Technology
Nonprofits
Biological Technologies
$2,000,000
U.S. Department of Defense (DARPA - Biological Technologies Office)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 2, 2025

This grant provides funding for innovative research projects that utilize biological technologies to enhance U.S. national security, targeting a wide range of applicants including nonprofits, educational institutions, and businesses.

Science and Technology
Nonprofits
Applied Mathematics
Contact for amount
National Science Foundation
Federal

Application Deadline

Nov 16, 2026

Date Added

Mar 17, 2025

This funding opportunity supports researchers in mathematics who are working on innovative solutions to scientific and engineering challenges, while also promoting the training of emerging applied mathematicians.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-SH-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 19, 2023

This funding opportunity provides financial support to a wide range of organizations, including state governments, universities, and nonprofits, to develop and implement programs focused on preventing injuries and promoting public health in communities across the U.S.

Health
State governments
Ocean Technology and Interdisciplinary Coordination
Contact for amount
National Science Foundation
Federal

Application Deadline

Feb 15, 2027

Date Added

Mar 5, 2025

This program provides funding for researchers to develop innovative oceanographic technologies and improve interdisciplinary collaboration in ocean science.

Science and Technology
Public and State controlled institutions of higher education
DoW Tuberous Sclerosis Complex, Idea Development Award
$800,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Aug 6, 2026

Date Added

May 6, 2026

This funding opportunity supports innovative research projects aimed at improving understanding and treatment of tuberous sclerosis complex, targeting areas such as neuropsychiatric disorders, tumor management, and patient care advancements.

Science and Technology
Nonprofits
ROSES25: F.17 Research Initiation Awards
$300,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 18, 2026

Date Added

May 21, 2026

This funding opportunity provides financial support to early-stage researchers affiliated with U.S.-based institutions to initiate projects that align with NASA's space and Earth science priorities.

Science and Technology
Public and State controlled institutions of higher education
DoW Neurofibromatosis Investigator-Initiated Research Award
$6,040,000
U.S. Department of Defense (Defense Health Agency Contracting Activity - DHACA)
Federal

Application Deadline

Sep 22, 2026

Date Added

Jun 26, 2026

This funding opportunity supports innovative research projects aimed at improving the understanding, diagnosis, and treatment of neurofibromatosis, a genetic disorder that causes tumors on nerve tissue, and is open to a wide range of researchers and institutions.

Science and Technology
Nonprofits
DoW, Ovarian Cancer, Ovarian Cancer Clinical Trial Academy Early-Career Investigator Award
$1,400,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 1, 2026

Date Added

May 5, 2026

This funding opportunity supports early-career researchers in ovarian cancer by providing financial resources and mentorship to develop their skills in conducting impactful clinical trials and translational research.

Health
Public and State controlled institutions of higher education
Rfa-Tp-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to a variety of organizations, including state governments, universities, and nonprofits, to implement innovative public health programs focused on preventing injuries and promoting safety in communities.

Health
State governments
DoW Traumatic Brain Injury and Psychological Health, Health Services Research Award
$4,000,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 15, 2026

Date Added

May 7, 2026

This funding opportunity provides up to $4 million for high-impact health services research projects that improve the prevention, diagnosis, and treatment of traumatic brain injury and psychological health issues affecting service members, veterans, and their families.

Health
Nonprofits
Biophotonics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This funding opportunity supports innovative engineering research that combines photonics with biology and medicine to develop advanced diagnostic and therapeutic technologies.

Science and Technology
Private institutions of higher education
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 5, 2026

Date Added

Nov 7, 2024

This funding opportunity supports collaborations between academic researchers and industry partners to develop and validate advanced imaging technologies that improve cancer detection and treatment.

Education
State governments
Research Interests of the Air Force Office of Scientific Research
$300,000
U.S. Department of Defense (Air Force Office of Scientific Research)
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 5, 2026

This funding opportunity supports universities, nonprofits, and research institutions in conducting high-risk, foundational scientific research that can advance military capabilities and contribute to commercial technologies.

Science and Technology
Public and State controlled institutions of higher education
Environmental Sustainability
$7,066,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This program provides funding for researchers to develop innovative engineering solutions that promote environmental sustainability and balance human needs with ecological preservation, while also involving graduate students and integrating social sciences.

Science and Technology
Public and State controlled institutions of higher education
Long Range Broad Agency Announcement (LRBAA) 24-01
Contact for amount
U.S. Department of Homeland Security (DHS), Science and Technology Directorate (S&T)
Federal
Rolling

Application Deadline

May 31, 2029

Date Added

Mar 18, 2025

This grant invites industry and academic researchers to propose innovative solutions that enhance homeland security across various mission areas, including counterterrorism, cybersecurity, and public safety.

Science and Technology
For profit organizations other than small businesses
Methodology, Measurement, and Statistics
$3,760,000
National Science Foundation
Federal

Application Deadline

Aug 27, 2026

Date Added

Feb 7, 2025

This program provides funding for innovative research in statistical methods and data collection techniques that benefit social, behavioral, and economic research, particularly through collaboration with federal statistical agencies.

Science and Technology
Individuals
Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
$3,600,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

May 16, 2028

Date Added

Jul 12, 2025

This funding opportunity provides financial support for clinical trials aimed at developing new treatments for rare diseases, benefiting a wide range of organizations involved in medical research and product development.

Agriculture
Nonprofits
Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 28, 2027

Date Added

Oct 31, 2024

This funding opportunity supports the development and clinical testing of innovative neural devices designed to treat nervous system or neuromuscular disorders, encouraging diverse participation and collaboration among various institutions and organizations.

Health
State governments